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degradable magnesium-hydroxyapatite interpenetrating phase composites processed by current assisted metal infiltration in additive-manufactured porous preforms

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Journal of Magnesium and Alloys 2022年第12期10卷 3641-3656页

作者： Mariano Casas-Luna Edgar B.Montufar Norbert Hort Sebastian Díaz-de-la-Torre JoséClaudio Méndez-García Lucie Vištejnová Adam Brínek AlešDanhel Karel Dvorak Jozef Kaiser Ladislav Celko Central European Institute of Technology Brno University of TechnologyPurkynova 123Brno 61200Czech Republic Institute of Metallic Biomaterials Helmholtz-Zentrum HereonMax-Planck-Straße 1Geesthacht 21502Germany Institute of Product and Process Innovation Leuphana University LüneburgUniversitätsallee 1Lüneburg 21335Germany Centro de Investigación e Innovación Tecnológica Instituto Politécnico NacionalCerrada de Cecati s/nMexico City 02250Mexico Biomedical Center Faculty of Medicine in PilsenCharles UniversityAlej Svobody 1655/76Plzen 32300Czech Republic Institute of Biophysics of the Czech Academy of Sciences Královopolská135Brno 61265Czech Republic Faculty of Civil Engineering Brno University of TechnologyPurkynova 139Brno 61200Czech Republic

This work explores ceramic additive manufacturing in combination with liquid metal infiltration for the production of degradable interpenetrating phase magnesium/hydroxyapatite(Mg/HA) composites. Material extrusion additive manufacturing was used to produce stoichiometric,and calcium deficient HA preforms with a well-controlled open pore network, allowing the customization of the topological relationship of the composite. Pure Mg and two different Mg alloys were used to infiltrate the preforms by means of an advanced liquid infiltration method inspired by spark plasma sintering, using a novel die design to avoid the structural collapse of the preform. Complete infiltration was achieved in 8 min, including the time for the Mg melting. The short processing time enabled to restrict the decomposition of HA due to the reducing capacity of liquid Mg. The pure Mg-base composites showed compressive yield strength above pure Mg in cast state. Mg alloy-based composites did not show higher strength than the bare alloys due to grain coarsening, but showed similar mechanical properties than other Mg/HA composites that have significantly higher fraction of metallic phase. The composites showed faster degradation rate under simulated body conditions than the bare metallic component due to the formation of galvanic pairs at microstructural level. Mg dissolved preferentially over HA leaving behind a scaffold after a prolonged degradation period. In turn, the fast production of soluble degradation products caused cell metabolic changes after 24 h of culture with not-diluted material extracts. The topological optimization and reduction of the degradation rate are the topics for future research.

关键词： Interpenetrating phase composite Biodegradable metal Topological relationship Direct ink writing Metal infiltration Computed aided design

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Multi-omics Analysis of Young Portulaca oleracea ***’Responses to High NaCl Doses Reveals Insights into Pathways and Genes Responsive to Salinity Stress in this Halophyte Species

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Phenomics 2023年第1期3卷 1-21页

作者： Vivianny Nayse Belo Silva Thalliton Luiz Carvalho da Silva Thalita Massaro Malheiros Ferreira Jorge Candido Rodrigues Neto AndréPereira Leão JoséAntônio de Aquino Ribeiro Patrícia Verardi Abdelnur Leonardo Fonseca Valadares Carlos Antônio Ferreira de Sousa Manoel Teixeira Souza Júnior Graduate Program of Plant Biotechnology Federal University of LavrasCP 3037LavrasMG 37200-000Brazil Institute of Chemistry Federal University of GoiásCampus SamambaiaGoiâniaGO 74690‐900Brazil Brazilian Agricultural Research Corporation Embrapa Mid-NorthTeresinaPI 64008-780Brazil Brazilian Agricultural Research Corporation Embrapa AgroenergyBrasíliaDF 70770‐901Brazil

Soil salinity is among the abiotic stressors that threaten agriculture the most,and purslane(Portulaca oleracea L.)is a dicot species adapted to inland salt desert and saline habitats that hyper accumulates salt and has high phytoremediation *** researchers consider purslane a suitable model species to study the mechanisms of plant tolerance to drought and salt ***,a robust salinity stress protocol was developed and used to characterize the morphophysiological responses of young purslane plants to salinity stress;then,leaf tissue underwent characterization by distinct omics platforms to gain further insights into its response to very high salinity *** salinity stress protocol did generate different levels of stress by gradients of electrical conductivity at field capacity and water potential in the saturation extract of the substrate,and the morphological parameters indicated three distinct stress *** expected from a halophyte species,these plants remained alive under very high levels of salinity stress,showing salt crystal-like structures constituted mainly by Na^(+),Cl^(−),and K^(+)on and around closed stomata.A comprehensive and large-scale metabolome and transcriptome single and integrated analyses were then employed using leaf *** multi-omics integration(MOI)system analysis led to a data-set of 51 metabolic pathways with at least one enzyme and one metabolite differentially expressed due to salinity *** data sets(of genes and metabolites)are valuable for future studies aimed to deepen our knowledge on the mechanisms behind the high tolerance of this species to salinity *** conclusion,besides showing that this species applies salt exclusion already in young plants to support very high levels of salinity stress,the initial analysis of metabolites and transcripts data sets already give some insights into other salt tolerance mechanisms used by this species to support high levels of salinity stress.

关键词： Purslane RNA-Seq Chemometrics High-resolution mass spectrometry Abiotic stress Multi-omics integration

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前曲扭角增加式叶尖气动特性研究

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太阳能学报 2022年第3期43卷 288-293页

作者：田德陶立壮新能源电力系统国家重点实验室(华北电力大学) 北京102206

以某150 kW水平轴的风电机组叶片为研究对象,提出一种朝来流风方向圆弧式前曲、扭角增加的降载叶尖外形;建立以扭角增量A、弯曲角度B为变量的16组叶尖几何模型,为探究该降载设计叶片最佳适用风况,建立考虑扭角增量、弯曲角度及风速的三... 详细信息

以某150 kW水平轴的风电机组叶片为研究对象,提出一种朝来流风方向圆弧式前曲、扭角增加的降载叶尖外形;建立以扭角增量A、弯曲角度B为变量的16组叶尖几何模型,为探究该降载设计叶片最佳适用风况,建立考虑扭角增量、弯曲角度及风速的三因素四水平正交试验表,借助ICEM完成多组仿真模型的网格划分,利用Fluent单一旋转坐标系法对叶片进行流场分析,获得各组模型的转矩、推力等参数,采用因子效应对风速、弯曲角度、扭角增量进行评估。结果表明,在接近约9 m/s风速时,叶尖扭角增量为10°,弯曲角度为30°的前曲增扭叶片具有最优的降载特性,相较于初始叶片,在保证功率基本不损失的情况下,轴向推力减少约6.5%。

关键词：风电机组叶片优化流场正交试验

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Stretchable and self-healable spoof plasmonic meta-waveguide for wearable wireless communication system

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Light(Science & Applications) 2022年第11期11卷 2725-2737页

作者： Bu-Yun Yu de-Wei Yue Ke-Xin Hou Lu JU Hao Chen Cong Ding Zhen-Guo Liu Yun-Qian Dai Hari Krishna Bisoyi Ying-Shi Guan Wei-Bing Lu Cheng-Hui Li Quan Li State Key Laboratory of Millimeter Waves School of Information Science and EngineeringSoutheast UniversityNanjing 210096China Center for Flexible RF Technology Frontiers Science Center for Mobile Information Communication and SecuritySoutheast UniversityNanjing 210096China Purple Mountain Laboratories Nanjing 21111China State Key Laboratory of Coordination Chemistry School of Chemistry and Chemical EngineeringNanjing UniversityNanjing 210023China Institute of Advanced Materials and School of Chemistry and Chemical Engineering Southeast UniversityNanjing 211189China Advanced Materials and Liquid Crystal Institute and Chemical Physics Interdisciplinary Program Kent State UniversityKentOH 44242USA

Microwave transmission lines in wearable systems are easily damaged after frequent mechanical deformation,posing a severe threat to wireless ***,we report a new strategy to achieve stretchable microwave transmission lines with superior reliability and durability by integrating a self-healable elastomer with serpentine-geometry plasmonic meta-waveguide to support the spoof surface plasmon polariton(SSPP).After mechanical damage,the self-healable elastomer can autonomously repair itself to maintain the electromagnetic performance and mechanical ***,the specially designed SSPP structure exhibits excellent stability and damage *** if the self-healing process has not been completed or the eventual repair effect is not ideal,the spoof plasmonic meta-waveguide Can still maintain reliable ***-healing material enhances strength and durability,while the SSPP improves stability and gives more tolerance to the self-healing *** design coordinates the structural design with material synthesis to maximize the advantages of the SSPP and self-healing material,signifcantly improving the relability and durability of stretchable microwave transmission *** also perform communication quality experiments to demonstrate the potential of the proposed meta-waveguide as interconnects in future body area network systems.

关键词： process durability maintain

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Palm Red Mite Management with Soursop Seed Plant Residue Extracts

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Agricultural Sciences 2023年第4期14卷 541-552页

作者： Ana Beatriz Mamedes Piffer Evellyn Zuqui Bolsoni Isabella Merlo Fornaciari Anderson Mathias Holtz Johnatan Jair de Paula Marchiori Jose Romário de Carvalho Ronilda Lana Aguiar Patrícia Soares Furno Fontes Bruna de Oliveira Magnani Campus Itapina Federal Institute of Espírito Santo Colatina Brazil Campus Seropédica Federal University Rural of Rio de Janeiro Seropédica Brazil Secretary of State for Education of Espírito Santo Gua&#231uí Brazil

Raoiella indica Hirst, 1924 (Prostigmata: Tenuipalpidae), is one of the leading pest mites in palm and banana trees, however, there are few control methods available for this pest species. Therefore, this work aimed to evaluate the acaricidal effect of soursop seed extract (Annona muricata L.) on R. indica adults. The experiment was conducted in a completely randomized design using soursop seed extract with 7 replicates and 12 individuals of R. indica per replicate. The experimental units consisted of discs of coconut palm leaves (4 cm in diameter), with cotton moistened at the bottom of the Petri dish (10.0 × 1.2 cm) and around the disc to maintain turgor and prevent mites from escaping. The application was performed using an airbrush, connected to a calibrated compressor with a constant pressure of 1.3 psi and 1 mL of solution per repeat plate. The acaricidal effect was evaluated 24, 48, and 72 hours after spraying. Mortality data were corrected and submitted to Probit analysis (p ≤ 0.05) using the statistical program R, with the LC50 and LC90 calculated for the extract. At the maximum concentration (15%), the soursop seed extract showed mortality of 70% of individuals of R. indica, and the LC50 was 6.58%. It was concluded that the soursop seed extract showed acaricidal potential on R. indica in the laboratory.

关键词： Annona muricata Raoiella indica Alternative Control Agro-Industrial Residue

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Predictive value of preoperative albumin-bilirubin score and other risk factors for short-term outcomes after open pancreatoduodenectomy

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世界临床病例杂志 2023年第26期11卷 6051-6065页

作者： Hana Zavrtanik Davide Cosola David Badovinac Benjamin Hadžialjević Gašper Horvat Danaja Plevel Selene Bogoni Paola Tarchi Nicolòde Manzini AlešTomažič department of Abdominal Surgery University Medical Centre LjubljanaLjubljana 1000Slovenia Clinica Chirurgica Azienda Sanitaria Universitaria Giuliano IsontinaCattinara HospitalTrieste 34149Italy department of Medical Surgical and Health SciencesUniversity of TriesteTrieste 34149Italy Faculty of Medicine University of LjubljanaLjubljana 1000Slovenia

BACKGROUND Pancreatoduodenectomy represents a complex procedure involving extensive organ resection and multiple alimentary *** is still associated with high morbidity,even in high-volume *** tools including preoperative patient-related factors to preoperatively identify patients at high risk for postoperative complications could enable tailored perioperative management and improve patient *** To evaluate the clinical significance of preoperative albumin-bilirubin score and other risk factors in relation to short-term postoperative outcomes in patients after open *** This retrospective study included all patients who underwent open pancreatic head resection(pylorus-preserving pancreatoduodenectomy or Whipple resection)for various pathologies during a five-year period(2017-2021)in a tertiary care setting at University Medical Centre Ljubljana,Slovenia and Cattinara Hospital,Trieste,***-term postoperative outcomes,namely,postoperative complications,postoperative pancreatic fistula,reoperation,and mortality,were evaluated in association with albumin-bilirubin score and other risk *** logistic regression models were built to identify risk factors associated with these short-term postoperative *** Data from 347 patients were *** complications,major postoperative complications,postoperative pancreatic fistula,reoperation,and mortality were observed in 52.7%,22.2%,23.9%,21.3%,and 5.2%of patients,*** was no statistically significant association between the albumin-bilirubin score and any of these short-term postoperative complications based on univariate *** controlling for other predictor variables in a logistic regression model,soft pancreatic texture was statistically significantly associated with postoperative complications[odds ratio(OR):2.09;95%confidence interval(95%CI):1.19-3.67];male gender(OR:2.12;95%CI:1.15-3.93),soft pan

关键词： Pancreatoduodenectomy Albumin Bilirubin Postoperative complications Pancreatic fistula Perioperative care

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Promoting integrative medicine by computerization of traditional Chinese medicine for scientific research and clinical practice: The SuiteTCM Project

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Journal of Integrative Medicine 2013年第2期11卷 135-139页

作者： Arthur de Sá Ferreira Laboratory of Computational Simulation and Modeling in Rehabilitation Post-graduation Program of Rehabilitation Science Augusto Motta University Center

BACKGROUND： Chinese and contemporary Western medical practices evolved on different cultures and historical contexts and, therefore, their medical knowledge represents this cultural divergence. Computerization of traditional Chinese medicine （TCM） is being used to promote the integrative medicine to manage, process and integrate the knowledge related to TCM anatomy, physiology, semiology, pathophysiology, and therapy. METHODS： We proposed the development of the SuiteTCM software, a collection of integrated computational models mainly derived from epidemiology and statistical sciences for computerization of Chinese medicine scientific research and clinical practice in all levels of prevention. The software includes components for data management （DataTCM）, simulation of cases （SimTCM）, analyses and validation of datasets （SciTCM）, clinical examination and pattern differentiation （DiagTCM, TongueTCM, and PulseTCM）, intervention selection （AcuTCM, HerbsTCM, and DietTCM）, management of medical records （ProntTCM）, epidemiologic investigation of sampled data （ResearchTCM）, and medical education, training, and assessment （StudentTCM）. DISCUSSION： The SuiteTCM project is expected to contribute to the ongoing development of integrative medicine and the applicability of TCM in worldwide scientific research and health care. The SuiteTCM 1.0 runs on Windows XP or later and is freely available for download as an executable application.

关键词： traditional Chinese medicine evidence-based practice computer-assisted decision making

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超声评估类风湿关节炎患者手和前足滑膜炎的相关性

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风湿病与关节炎 2024年第3期13卷 13-17页

作者：苗青温德惠高辰玮胡敏霞任占芬张文静徐大奎唐山市工人医院河北唐山063000 河北北方学院附属第一医院河北张家口075000

目的:通过对类风湿关节炎患者手部及足部关节进行超声检查,结合临床指标,预测类风湿关节炎患者前足滑膜炎存在的相关因素,便于临床医师关注病情变化,及时调整治疗方案。方法:收集类风湿关节炎患者69例,对其均行二维和能量多普勒(PDUS)检... 详细信息

目的:通过对类风湿关节炎患者手部及足部关节进行超声检查,结合临床指标,预测类风湿关节炎患者前足滑膜炎存在的相关因素,便于临床医师关注病情变化,及时调整治疗方案。方法:收集类风湿关节炎患者69例,对其均行二维和能量多普勒(PDUS)检查,并收集其临床指标。根据二维超声跖趾关节滑膜是否增厚将患者分为前足受累组19例和前足未受累组50例,对比2组之间临床指标和超声结果的差异,评估临床指标及手部关节超声结果与足部关节超声结果之间的相关性。结果:①前足受累组关节肿胀数(SJC)、患者的总体评估(PGA)、医师的总体评估(EGA)、DAS28评分、临床疾病活动度评分(CDAI)、手PDUS总分、手PDUS阳性关节数均明显高于前足未受累组,差异有统计学意义(P5分时与跖趾关节滑膜炎有关,敏感性为90%,特异性为78%,提示手部PDUS评分与跖趾关节滑膜炎存在相关性。结论:手PDUS总分对于提示类风湿关节炎患者跖趾关节滑膜炎的存在具有很好的价值。

关键词：类风湿关节炎超声检查跖趾关节滑膜炎

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Are Off-Field Activities an Underestimated Risk for Hamstring Injuries in Dutch Male Amateur Soccer Players?An Exploratory Analysis of a Prospective Cohort Study

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Journal of Science in Sport and Exercise 2022年第1期4卷 28-36页

作者： Jur J.Brauers Peter Alexander van de Hoef Maarten van Smeden Frank J.G.Backx Michel S.Brink department of Rehabilitation Physical Therapy Science and SportsUtrecht UniversityUniversity Medical Center UtrechtBrain CenterUtrechtThe Netherlands Julius Center for Health Sciences and Primary Care University Medical Center UtrechtUtrecht UniversityUtrechtThe Netherlands Center for Human Movement Sciences University of GroningenUniversity Medical Center GroningenGroningenThe Netherlands

Purpose The purpose of this study was to explore what extent male amateur soccer players participate in off-field activities and whether these off-field activities are associated with the development of hamstring *** Amateur soccer players(n=399)from first-class selection teams(n=32)filled out a baseline screening question-naire concerning off-field activities(i.e.,work and study type and hours,traveling time,sleep,energy costs,and time spent on other activities)and their history of hamstring injury as a part of a cluster-randomized controlled *** one competition,the players reported weekly their hamstring injuries,which were verified by medical/technical ***-able Firth corrected logistic regression models were used to explore associations between off-field activities and hamstring *** Sixty-five hamstring injuries were *** injury was significantly associated with hamstring injuries(OR ranging from 1.94[95%CI 1.45-2.61]to 2.02[95%CI 1.49-2.73]),but off-field activities were *** Although amateur soccer players spent a relatively large amount of time on off-field activities,we did not find off-field activities measured at baseline to be associated with hamstring injuries in the subsequent competitive soccer *** contrast,previous hamstring injury was found to be strongly associated with(recurrent)hamstring injuries.

关键词： Risk factors Activities of daily living Psychosocial factors Football Athletic injuries

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The Dialectics of China＇s Foreign Aid： Interactions Shaping China＇s Aid Policy

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Fudan Journal of the Humanities and Social Sciences 2015年第4期8卷 617-648页

作者： Ward Warmerdam Arjan de Haan Kortenaerkade 12 2518LT Den Haag The Netherlands

China’s foreign aid has received much attention, but the knowledge of its determinants is limited. We show how domestic political forces interact with international circumstances to shape Chinese aid policies. The article applies Carol Lancaster’s framework on the interaction of domestic ideas, institutions, and interests in the development of foreign aid policy. We describe the dynamics of the Chinese domestic context and the interaction of these forces with international circumstances. The article concludes that shifts in ideology and interest both facilitated and required changes in the foreign aid program. While other countries are subject to similar domestic political forces, China appears relatively unique as donor because of large oscillations and simultaneous continuity of its aid program under the pressure of these domestic political forces.

关键词： Chinese foreign aid Domestic political forces Aid determinants Geopolitics

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