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Profile and Antibiotic Sensitivity of Acute Pyelonephritis in Children at Gabriel Toure Teaching Hospital, Bamako

Open Journal of Pediatrics 2020年第1期10卷 94-108页

作者： Djeneba Konate Lala N’Driany Sidibe Karamoko Sacko Bakary Kone Adama Kone Aminata Doumbia Fatoumata Tiero Pierre Togo Fatouamata Leonie Diakite abdoul Karim Doumbia Belco maiga Fousseyni Traore Aamadou Toure Hawa Diall Mohamed Elmouhouloud Cisse Adama Dembele Oumar Coulibaly Yacouba Aba Coulibaly H.Konare Isabelle Traore Guediouma Dembele Issiaka Kone Leyla maiga Ibrahima Ahamadou abdoul aziz Diakite Boubacar Togo Mariam Sylla Fatoumata Dicko-Traore Pediatric Department CHU Gabriel ToureBamakoMali Pediatric Unit Hospital Center Mother-ChildLuxembourgLuxembourg

Background: Very common symptom in children, fever, perhaps a warning sign of more or less severe pathology, rapidly progressive, including an invasive bacterial infection such as acute pyelonephritis (APN). The aim of this work was to study the bacteriological profile and antibiotic sensitivity of APN in children. Methods: A prospective study involving any infant or child aged 3 months to 15 years with an acute fever (≥38°C) in which a urine test strip was performed in the pediatric department of the teaching hospital Gabriel Toure between April 1st and May 15th, 2019 (45 days). Results: 124 children were included out of 244 febrile patients. Infants (3 - 23 months) predominated (52.8%) with a sex ratio of 2. Seventy-five percent of children came directly from home and 30.6% were on antibiotic prior to admission. The urine bag sample was taken in 55.6% and the urine was macroscopically cloudy in 32.3%. Stigmas of urinary tract infection at the urinary strip were present in 56.5%. Confirmation of acute pyelonephritis (APN) by CytoBacteriological Urine Examination (CBUE) was 29% with Escherichia coli (63.9%) or Enterococcus faecalis (30.5%). Sensitivity was excellent for ciprofloxacin and imipenem (100%). The overall resistance was greater for gentamicin, cotrimoxazole, ceftriaxone, cefotaxime and amoxicillin-clavulanic acid (Threshold: 17.9% - 95.6%). APN was associated with bacteremia in 2.8% with hospitalization for 45.2% and mortality of 11.1% (due to severe acute malnutrition, severe dehydration and multifocal infection). Conclusion: The APN, daily activity of pediatrician in Bamako, is observed in one third of febrile children associated with a major life-threatening condition of risk factors, then the likely antibiotherapy could be amikacin in our context.

关键词： APN Fever Child Bamako

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Clinico-Pathological Profile of Malignant Abdominal Tumors in Children: Experience of the Pediatric Oncology Unit in Bamako

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Open Journal of Pediatrics 2021年第4期11卷 608-617页

作者： abdoul Karim Doumbia Adama Dembele Pierre Togo Oumar Coulibaly Arsene Dackono Mohamed Elmouloud Cissé Fousseyni Traoré Hawa Diall Boubacar Togo abdoul aziz Diakité Yakaria Coulibaly Cheick Bougadary Traore Lala N’drainy Sidibe Belco maiga Diakite Fatoumata Léonie Francois Karamoko Sacko Djeneba Konaté Guediouma Dembele Hacimi Poma Adama Bah Djibril Kassogue Oumar Keita Ibrahim Ahamadou Department of Pediatrics at CHU Gabriel Touré Bamako Mali Pediatric Surgery Department of the Gabriel Touré CHU Bamako Mali Pathological Anatomy and Cytology Department of the “Point G” CHU Bamako Mali

Introduction: the objective was to describe the epidemiological and histological aspects of malignant abdominal tumors in children. Methodology: This was a descriptive, cross-sectional study conducted from January 1, 2017 to December 31, 2018. We included all patients aged 0 to 15 years with histologically confirmed abdominal malignancies. Results: We collected 46 files of malignant tumors of the abdomen (35% of pediatric cancers). The majority of patients were under 5 years old (65%). The sex ratio was 1.7. They were generally from disadvantaged socio-economic backgrounds (67%). The average consultation time was 50 days. The main reasons for consultation were abdominal mass (48%), pain (17%) or distension (9%). The mass was large, hard (89%), immobile (71%) and painful (46%). Malnutrition was found in 80% of patients. The mass was retro-peritoneal in 63% of cases and renal in 54%. It was solid in 94% of cases and heterogeneous in 76% of cases. The assay for tumor markers was not performed. Anemia was present in all patients. Fine needle aspiration was performed in 43%, biopsy in 37% and myelogram in 15% of cases. spinal cord involvement was observed in 28% of Burkitt’s cases. The main cancers diagnosed were nephroblastoma (52%), Burkitt’s lymphoma (26%) and neuroblastoma (13%). Stage 1 and stage 2 were frequent in 20% and 22% of cases, respectively;36% of cases were not staged. The average duration of chemotherapy was 11 weeks. Total resection was performed in 30% of cases. The outcome of the patients was marked by total remission in 65%. Conclusion: Abdominal malignancies are very common in children. The diagnosis of certainty is late in our context.

关键词： Cancer Abdomen Child Sub-Saharan Africa

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Epidemiologic Features of the First Flare of Ne-phrotic Syndrome in Children in Bamako Pedi-atric Hospitals

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Open Journal of Pediatrics 2022年第2期12卷 389-395页

作者： Djeneba Konaté Lala Ndrayni Sidibé Amadou Touré Adama Fomba abdoul Karim Doumbia Karamoko Sacko Aminata Doumbia Oumar Coulibaly Mohamed Elmouloud Cissé Pierre Togo Adama Dembélé Awa Konaré Belco maiga Harber Balilé Fatoumata Léonie Françoise Diakité Fousseyni Traoré Hawa Gouro Diall Ibrahima Ahamadou Guédiouma Dembélé abdoul aziz Diakité Fatoumata Dicko Traoré Boubacar Togo Department of Pediatrics CHU Gabriel Touré Bamako Mali

Introduction: The most frequent glomerular pathology in children, nephrotic syndrome (NS) is a cosmopolitan affection. It is an immunological disease and certain environmental factors, in particular viral infections and allergens, influence its occurrence. The climatic and environmental differences coupled with the frequency of infectious pathologies signing the African particularity and the absence of data in Mali on this affection, motivated us to carry out this work. Objective: To study the epidemiological aspects of nephrotic syndrome in hospitalized children aged 0 - 15 years. Patients and Methods: This was a descriptive prospective study from January 1 to December 31, 2021 in the Pediatrics Department of the University Teaching Hospital (UTH) Gabriel Touré, anational pediatric reference service in Mali. Diagnostic confirmation was provided by biology. Results: In one year, 120 children were hospitalized for nephrotic syndrome with a sex ratio of 2.75. Male exclusivity was observed at the ages of one year, eight years and 14 years and a reversal at 13 years (sex-ratio = 0.33). The median age was 6 years for an average age of 6.4 years ± 2.4 years with extremes ranging from one year to 14 years. The first attack of nephrotic syndrome occurred outside the classic age (>10 years) in 16.67%. Nephrotic syndrome is observed throughout the year with two peaks in summer (July to September) and winter (December to February). Many ethnic groups were affected by this condition with a high frequency among ethnic groups where endogamy is common. All patients were melanoderms. No cases of NS were recorded in Caucasian children from Northern Mali. The patients came from Bamako in 47.5% of cases. Two brothers from the same siblings had had their first attack of nephrotic syndrome the same year, ten months apart. Conclusion: Nephrotic syndrome in pediatric hospitals of Bamako occurs at a median age of six years all along the year with a summer and winter peaks. It is more obser

关键词： Epidemiology Nephrotic Syndrome Child University Teaching Hospital Ga-briel Toure

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Initial Experience with Open Heart Surgery in Sub-Saharan Africa:Challenges in Mali with Minimum Standards for Practice

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World Journal of Cardiovascular Surgery 2019年第9期9卷 108-118页

作者： Seydou Togo Moussa abdoulaye Ouattara abdoul aziz maiga Moussa Bazongo Issa Boubacar maiga Cheik Ahmed Sekou Toure Ibrahim Coulibaly Sounkalo Diop Allaye Ombotimbe Sitta Illiassou Souleymane Coulibaly Mamadou Solo Koita Koumba Nelly Dora Ignanga Sanibe Dramane Kone Moussa Oscar Kamano Fatoumata Konate Adama Issa Kone Amadou Sidibe Ahmadou Drame Nouhoum Oueloguem Bourama Kane Boubacar Drame Sekou Koumare Zimogo Zie Sanogo Sadio Yena Department of Thoracic and Cardiovascular Surgery Mali HospitalBamakoMali Department of Anesthesiology and Critical Care Mali HospitalBamakoMali Department of Cardiologie Mali HospitalBamakoMali Department of Pediatrics Mali HospitalBamakoMali Department of Biomedical Laboratory Mali HospitalBamakoMali Department of Surgery“A” Point G HospitalBamakoMali

Introduction: There has been limited experience with Open Heart Surgeries (OHS) in Sub-Saharan Africa. In west Africa especially in Mali, most fledgling centers are unable to overcome the myriad of challenges encountered in establishing OHS though there is a high prevalence of surgically correctable heart diseases. The aim of this paper is to review our initial experience of our first cases in developing OHS program and discuss the challenges and prospects that need to be overcome to further develop it. Methods: A total of 6 patients who underwent OHS during the first “cardiac mission” in July 2016 were included in this retrospective study. The medical records of the patients were examined and data on age, sex, diagnosis, EuroSCORE, type of surgery, cardiopulmonary bypass details, complications and length of hospital stay were extracted. Results: Six patients with a male to female ratio of 1, ages ranging between 12 and 35 years (mean of 22.5 ± 12 years) were studied. The mean of EuroSCORE was 6 ± 41. Pericardial patch closure of isolated atrial septal defect was performed in one patient. One patient had mitral valve repair for rheumatic mitral regurgitation consisting of chordal shortening with a tricuspid valvuloplasty. Three patients had mitral valve replacement with tricuspid valvuloplasty. Four patients had mitral valve replacement. Sixty-day mortality?was 0%. Conclusion: Safe conduct of open heart surgery in Mali Hospital setting is feasible. Grant financial aid is required for rapid growth of Open-Heart Surgery in this part of Sub-Saharan Africa.

关键词： Open-Heart Surgery Mali Africa

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Hemorrhagic Stroke: About a Pediatric Case

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Open Journal of Pediatrics（儿科学期刊） 2021年第4期

作者： abdoul Karim Doumbia Oumar Coulibaly Hawa Gouro Diall GuedioumaDembélé Agaly Hamadassaliha Fatou S. Mangara Pierre Togo AdamaDembélé Belco maiga Karamoko Sacko abdoul aziz Diakité Boubacar Togo

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Early Management of Nephroblastoma: A Single-Center Study in a Sub-Saharan African Country

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Open Journal of Pediatrics（儿科学期刊） 2021年第4期

作者： abdoul Karim Doumbia Pierre Togo Mariam maiga Mohamed Elmouloud Cissé GuédioumaDembélé Oumar Coulibaly Karamoko Sacko Belco maiga Djeneba Konaté Abdou Diarra Yakaria Coulibaly Fatoumata Léonie Diakité abdoul aziz Diakité Boubacar Togo Check Bougadary Traore Adama Bah

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Study of the Management of Children with Major Sickle Cell Disease in Pediatric Emergencies at the Gabriel Toure University Hospital

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Open Journal of Pediatrics（儿科学期刊） 2023年第2期

作者： Mohamed Elmouloud Cissé abdoul aziz Diakité AdamaDembélé Belco maiga Fatoumata Nampomo Diarra Oumar Coulibaly Hawa Diall Pierre Togo abdoul Karim Doumbia abdoulaye Barry Karamoko Sacko Fousseyny Traore Djeneba Konaté Kalirou Traoré LalaN’DrainySidibé Ibrahim Ahamadou Amadou Touré Fatoumata Dicko Boubacar Togo Mariam Sylla

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Systemic Lupus Erythematosus Complicated by Pericarditis:A Case Report from the Guindo Clinic in Bamako, Mali

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Open Journal of Pediatrics（儿科学期刊） 2023年第1期

作者： Kalirou Traoré Karamoko Sacko Souleymane Mariko Belco maiga Hawa Konaré AdamaDembélé Mohamed Cissé Fousseyni Traoré Ibrahim Dollo Fatoumata Traore Arouna Ouattara Aminata Doumbia Mamadou Traore Djeneba Konate Pierre Togo abdoul Karim Doumbia Gassama Diaby abdoul aziz Diakité Ali Guindo Fatoumata Dicko Mariam Sylla Boubacar Togo

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Study of Cerebral Vascular Accidents in Children with Sickle Cell from 6 Months to 15 Years of Age at the Gabriel Toure University Hospital Center

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Open Journal of Pediatrics（儿科学期刊） 2023年第6期

作者： Mohamed Elmouloud Cissé abdoul aziz Diakité Adama Dembélé Belco maiga Moussa Diallo abdoul Karim Doumbia Oumar Coulibaly Pierre Togo Hawa Gouro Diall abdoulaye Barry Karamoko Sacko Amadou Touré Issa Sanou Fousseyny Traore Djeneba Konaté Kalirou Traoré LalaN’Drainy Sidibé Bory Traoré Ibrahim Ahamadou Yacouba Aba Coulibaly Hawa Konaré Aminata Doumbia

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Seizures in Children under Five in a Pediatric Ward: Prevalence, Associated Factors and Outcomes

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Open Journal of Pediatrics（儿科学期刊） 2021年第4期

作者： abdoul Karim Doumbia OumouKoné GuédioumaDembélé Adama Dembelé Oumar Coulibaly Hawa Gouro Diall Karamoko Sacko Amadou Touré Pierre Togo abdoul aziz Diakité Mohamed Elmouloud Cissé Belco maiga Djeneba Konaté Fatoumata Léonie Diakité Lala N’drainy Sidibe Fousseyni Traoré Adama Bah Djibril Kassogue Boubacar Togo Madou Traoré

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