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Fracture Healing in a Denervation and/or Nerve Ending Interpositioning Model in the Rat

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International Journal of Clinical Medicine 2011年第3期2卷 301-306页

作者： Cagri Yegengil mahmut pekedis Hasan Yildiz 不详

Background: In this experimental study, we aimed to determine the possible changes in fracture healing due to denervation and/or nerve ending interpositioning. Methods: 50 Wistar Albino type male rats were divided into three study groups. A standard transverse diaphysial fracture in the femurs of the same side of all subjects under anesthesia was created and the fracture were fixed intramedullarily. While preserving the structural integrity of the sciatic nerve in the first group, neurectomy to the nerve in the second group was performed. In the third group, following the sciatic nerve cut, the proximal end of the nerve were interposed the fracture line. After a 28-day observational period, the callus formation in the subjects was examined radiologically, biomechanically and histopathologically. Results: Among all groups, the third group subjects showed significant increase in radiological area measurements when they are compared to the second group rats. There was no significant difference in biomechanical measurements of fractured femurs of the three groups. In histopathological evaluations, it was observed that denervation had increased the thickness of the cartilage and the number of the chondrocytes and osteoclasts significantly but decreased the number of fibroblasts compared to the control group. In addition to the denervation nerve ending interpositioning increased the bone thickness and the number of the osteoblasts but decreased the number of the osteoclasts significantly. Conclusions: While radiological observations exhibit that nerve ending interpositioning has resulted more hypertrophic callus formation, histopathological evaluations led us to that denervation created partial (immature) callus formation and nerve ending interpositioning demonstrated larger but immature callus formation.

关键词： Denervation Nerve Ending Interposition Fracture Healing Callus Formation

Fracture Healing in a Denervation and/or Nerve Ending Interpositioning Model in the Rat

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Single incision laparoscopic surgery for hepatocellular carcinoma

International Journal of Clinical Medicine（临床医学国际期刊） 2011年第3期

作者： Cagri Yegengil mahmut pekedis Hasan Yildiz

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World Journal of Gastrointestinal Surgery 2024年第10期16卷 3078-3083页

作者： Ilhan Karabicak Kadir Yildirim mahmut Fikret Gursel Zafer Malazgirt Department of General Surgery Samsun VM Medicalpark HospitalSamsun 55200Türkiye

Single incision laparoscopic liver resection(SILLR)is the most recent develop-ment in the laparoscopic approach to the *** for hepatocellular carci-noma(HCC)has developed much more slowly than multiport *** far,195 patients completed SILLR for *** this paper,we reviewed all published papers about SILLR for HCC and discussed the feasibility of the SILLR,peri and postoperative findings,tricks of patient selection and whether SILLR compromise the oncological principles.

关键词： Single incision Laparoscopic liver surgery Liver resection Hepatocellular carcinoma Multiport laparoscopic liver resection

The Impact of Black Sea Sand Treatment Effectively Reducing Different Type of Pain

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Open Journal of Therapy and Rehabilitation 2024年第1期12卷 18-27页

作者： mahmut Tokaç Abdulbari Bener Fatma Nur Kesiktaş Bahar Dernek Semra Alkal Akkaya Zeynep Esra Akgün Department of Medicine and Education Unit School of Medicine Istanbul Medipol University Istanbul Türkiye Department of Biostatistics & Medical Informatics School of Medicine Istanbul Medipol University Istanbul Türkiye Department of Evidence for Population Health Unit School of Epidemiology and Health Sciences The University of Manchester Manchester UK Faculty of Medicine Health Sciences University Istanbul Physiotherapy Rehabilitation Training and Research Hospital Istanbul Türkiye Faculty of Medicine Health Sciences University Department of Physical Medicine and Rehabilitation Umraniye Training and Research Hospital Istanbul Türkiye Physical Medicine and Rehabilitation Vatan Clinics School of Medicine Istanbul Medipol University Istanbul Türkiye

Purpose: Low back pain (LBP), Gonarthrosis, knee, and Carpal Tunnel Syndrome have been regarded as affecting more than three-quarters’ of individuals in their lifetime. The aim of this study was conducted to determine and compare the effects of topical patients with sand compared with control related to Gonarthrosis, LBP, knee, and Carpal Tunnel Syndrome pain. Methods: This is a prospective case and control designed study based on 101 pain case with Sand and 101 control subjects. The interventional groups in addition either topical sand or without sand 2 months after the intervention were assessed. We assessed tolerability of an established pain perception scale by the Numeric Rating Scale (NRS). Categorical variables were compared using the chi-square (χ2) test. The paired t-test was used to compare the two groups before and after the intervention. One-way analysis of variance (ANOVA) was employed for comparison of several group means. Results: The study was based on 202 patients, 41 males (20.3%) and 161 females (79.7%). There were statistically significant differences between subjects with and without Sand in term of Gonarthrosis, Rheumatoid Arthritis LBP, knee, and Carpal Tunnel Syndrome pain (p = 0.033). Majority of patients were over age 55 years old (55%) and females 78 (77.2%). The mean score of total pain experience before and after the intervention was 7.41 ± 1.1 for black sand, and 4.24 ± 2.38 for without sand as control group. The mean scores of these 5 groups were highly significant before and after the intervention (p There was statistically highly significant in regarding subjects with Sand as compared with those before Sand after treatment mean score specifically with gonarthrosis before pain 7.23 ± 1.86 vs after treatment 4.54 ± 2.18 p < 0.001;rheumatoid arthritis before 8.28 ± 1.48 vs after treatment 4.80 ± 3.71 p < 0.001;Low Back Pain before 8.42 ± 1.83 vs after treatment 4.37 ± 1.52 p < 0.001;knee pain before 8.93 ± 0.89 vs after treat

关键词： Therapies Sand LBP Musculoskeletal Rheumatoid Arthritis Carpal Tunnel Syndrome

Correlating common breakage modes with impact breakage and ball milling of cement clinker and chromite

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International Journal of Mining Science and Technology 2020年第6期30卷 901-908页

作者： mahmut Camalan Mining Engineering Department Middle East Technical UniversityAnkara 06800Turkey

Understanding the mechanisms of the breakage of ore particles is important to predict the particle size distribution in size reduction *** paper aims to show the presence of common breakage modes in impact breakage and ball milling of the cement clinker and chromite *** that purpose,narrow size fractions of the two samples were broken in a drop-weight tester or ball mill by changing the degree of applied *** the resultant size distributions were evaluated to seek evidence for the common breakage *** results showed that increasing the breakage energy will produce a systematic change in the shapes of the size distributions,suggesting a sequential set of breakage *** breakage is initially due to tensile stresses at low breakage energies and compressive stresses at high breakage *** studies should be done to assess if these breakage modes occur at sizereduction of different ores.

关键词： Progeny distribution Impact breakage Ball mill Self-similarity Breakage modes Cone of fines

Prediction of Excess Air Factor in Automatic Feed Coal Burners by Processing of Flame Images

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Chinese Journal of Mechanical Engineering 2017年第3期30卷 722-731页

作者： Muhammed Fatih TALU Cem ONAT mahmut DASKIN computer engineering department inonu university44280 MalatyaTurkey mechanical engineering department inonu university44280 MalatyaTurkey

In this study, the relationship between the visual information gathered from the flame images and the excess air factor 2 in coal burners is investigated. In conventional coal burners the excess air factor 2. can be obtained using very expensive air measurement instruments. The proposed method to predict ） for a specific time in the coal burners consists of three distinct and consecutive stages; a） online flame images acquisition using a CCD camera, b） extrac- tion meaningful information （flame intensity and bright- ness）from flame images, and c） learning these information （image features） with ANNs and estimate 2. Six different feature extraction methods have been used： CDF of Blue Channel, Co-Occurrence Matrix, L-Frobenius Norms, Radiant Energy Signal （RES）, PCA and Wavelet. When compared prediction results, it has seen that the use of co- occurrence matrix with ANNs has the best performance （RMSE = 0.07） in terms of accuracy. The results show that the proposed predicting system using flame images can be preferred instead of using expensive devices to measure excess air factor in during combustion.

关键词： Excess air factor Flame images Coal burner

Enhancement of pacemaker induced stochastic resonance by an autapse in a scale-free neuronal network

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Science China(Technological Sciences) 2016年第3期59卷 364-370页

作者： YILMAZ Ergin BAYSAL Veli PERC Matjaz OZER mahmut epartment of Biomedical Engineering Engineering Faculty bülent Ecevit University Zonguldak 67100 Turkey Department of Physics Faculty of Sciences King Abdulaziz University Jeddah 21431 Saudi Arabia Faculty of Natural Sciences and Mathematics University of Maribor Korogka cesta 160 Maribor SI-2000 Slovenia Department of Electrical and Electronics Engineering Engineering Faculty bülent Ecevit University Zonguldak 67100 Tarkey

An autapse is an unusual synapse that occurs between the axon and the soma of the same neuron. Mathematically, it can be described as a self-delayed feedback loop that is defined by a specific time-delay and the so-called autaptic coupling strength. Recently, the role and function of autapses within the nervous system has been studied extensively. Here, we extend the scope of theoretical research by investigating the effects of an autapse on the transmission of a weak localized pacemaker activity in a scale-free neuronal network. Our results reveal that by mediating the spiking activity of the pacemaker neuron, an autapse increases the propagation of its rhythm across the whole network, if only the autaptic time delay and the autaptic coupling strength are properly adjusted. We show that the autapse-induced enhancement of the transmission of pacemaker activity occurs only when the autaptic time delay is close to an integer multiple of the intrinsic oscillation time of the neurons that form the network. In particular, we demonstrate the emergence of multiple resonances involving the weak signal, the intrinsic oscillations, and the time scale that is dictated by the autapse. Interestingly, we also show that the enhancement of the pacemaker rhythm across the network is the strongest if the degree of the pacemaker neuron is lowest. This is because the dissipation of the localized rhythm is contained to the few directly linked neurons, and only afterwards, through the secondary neurons, it propagates further. If the pacemaker neuron has a high degree, then its rhythm is simply too weak to excite all the neighboring neurons, and propagation therefore fails.

关键词： autapse self-delayed feedback neuron channel noise scale-free network

Effects of fractional-order PI controller on delay margin in single-area delayed load frequency control systems

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Journal of Modern Power Systems and Clean Energy 2019年第2期7卷 380-389页

作者： Vedat CELIK mahmut Temel OZDEMIR Kwang Y.LEE Department of Electrical and Electronics Engineering Faculty of EngineeringFirat UniversityElazigTurkey Department of Electrical and Computer Engineering Baylor UniversityWacoUSA

This study aims to determine the improvement effect on the delay margin if fractional-order proportional integral(PI) controller is used in the control of a singlearea delayed load frequency control(LFC) system. The delay margin of the system with fractional-order PI control has been obtained for various fractional integral orders and the effect of them has been shown on the delay margin as a third controller parameter. Furthermore,the stability of the system that is either under or over the delay margin is examined by generalized modified Mikhailov *** stability results obtained have been confirmed numerically in time domain. It is demonstrated that the proposed controller for delayed LFC system provides more flexibility on delay margin according to integer-order PI controller.

关键词： Delay dependent stability Delay margin Fractional-order proportional integral(PI) Generalized modified Mikhailov criterion Load frequency control with delay

Reciprocating sliding wear properties of sintered Al-B_(4)C composites

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International Journal of Minerals,Metallurgy and Materials 2022年第6期29卷 1261-1269页

作者： mahmut Can Şenel Yusuf Kanca Mevlüt Gürbüz Mechanical Engineering Department Ondokuz Mayıs UniversitySamsun 55169Turkey Mechanical Engineering Department Hitit UniversityÇorum 19169Turkey

The fabrication of boron carbide reinforced aluminum matrix composites(Al-B_(4)C)with various contents of B_(4)C(1wt%,6wt%,15wt%,and 30wt%)was performed by powder metallurgy,and the influence of the content of B_(4)C on their mechanical and tribological behavior was *** Al-30B_(4)C composites recorded the highest density(~2.54 g/cm^(3)),lowest porosity(4%),maximum Vickers hardness(HV~75),lowest weight loss(0.4 mg),and lowest specific wear rate(0.00042 mm^(3)/(N·m))under a load of 7 N,with an enhancement of 167%in hardness,a decrease of 75.8%in weight loss,and a decrease of 76.7%in the specific wear rate compared with pure *** addition,the scanning electron microscope images of the worn surface revealed that the Al-B_(4)C composite has the narrowest wear groove of 0.85 mm at a load of 7 N,and the main wear mechanism was observed as an abrasive wear *** to the friction analysis,the coefficient of friction between surfaces increased with increasing boron carbide content and with decreasing applied *** conclusion,B_(4)C is an effective reinforcement material in terms of tribological and mechanical performance of the Al-B_(4)C composites.

关键词： aluminum boron carbide composite wear friction