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World Journal of Clinical Cases 2025年第5期13卷 1-12页

作者： Mona Mohamed Ibrahim abdalla Jaiprakash Mohanraj Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetic retinopathy(DR)remains a leading cause of vision impairment and blindness among individuals with diabetes,necessitating innovative approaches to screening and *** editorial explores the transformative potential of artificial intelligence(AI)and machine learning(ML)in revolutionizing DR *** and ML technologies have demonstrated remarkable advancements in enhancing the accuracy,efficiency,and accessibility of DR screening,helping to overcome barriers to early *** technologies leverage vast datasets to identify patterns and predict disease progression with unprecedented precision,enabling clinicians to make more informed ***,AI-driven solutions hold promise in personalizing management strategies for DR,incorpo-rating predictive analytics to tailor interventions and optimize treatment *** automating routine tasks,AI can reduce the burden on healthcare providers,allowing for a more focused allocation of resources towards complex patient *** review aims to evaluate the current advancements and applic-ations of AI and ML in DR screening,and to discuss the potential of these techno-logies in developing personalized management strategies,ultimately aiming to improve patient outcomes and reduce the global burden of *** integration of AI and ML in DR care represents a paradigm shift,offering a glimpse into the future of ophthalmic healthcare.

关键词： Diabetic retinopathy Artificial intelligence Machine learning Screening Management Predictive analytics Personalized medicine

ECCM schemes in netted radar system based ontemporal pulse diversity

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Journal of Systems Engineering and Electronics 2016年第5期27卷 1001-1009页

作者： ahmed abdalla zhao yuan bin tang School of Electronic Engineering University of Electronic Science and Technology of China Chengdu 611731 China

For a netted radar system to counteract the deceptionelectronic countermeasure （ECM） signals, an effective electroniccounter countermeasure （ECCM） approach is proposed. The proposedapproach is realized based on the new signaling strategyfor the temporal pulse diversity, which makes use of transmittingpulses at each pulse repetition interval （PRI） with specific transmissionpulse block, and then following proper processing andinformation fusion. The existence of the deceptive ECM signal isconfirmed by one station, while the other stations in the nettedradar with same parameters applied the pulse diversity ***, this method ensured that, pulse diversity can be appliedin netted radar. The performance assessment shows that theproposed solutions are effective in presence of ECM signals. Thisalgorithm has been demonstrated by simulations. The presentedsimulation results are in excellent consensus with theoretical predictions.

关键词： pulse diversity electronic counter countermeasure(ECCM) digital radio frequency memory (DRFM) electronic countermeasure(ECM) netted radar matching filter.

Multi Criteria Decision Making System for Parking System

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Computer Systems Science & Engineering 2021年第1期36卷 101-116页

作者： Manjur Kolhar abdalla Alameen College of Arts and Science Prince Sattam bin Abdulaziz University11990Saudi Arabia

System supported smart parking can reduce traffic by making it stress free to locate empty parking spaces,hence lowering the risk of unfocussed *** this study,we propose a smart parking system using deep learning and an application-based *** system has two modules,one module detects and recognizes a license plate(LP),and the other selects a parking space;both modules use deep learning *** used two modules that work independently to detect and recognize an LP by using an image of the *** detect parking space,only deep learning techniques were *** two modules were compared with other state-of-the-art *** utilized the You Only Look Once(YOLO)architecture to detect and recognize an LP because its performance in the context of Saudi Arabian LP numbers was superior to that of other *** with existing state-of-the-art solutions,the performance of the proposed solution was more *** solution can be further improved for use in the city and large organizations that have priority parking spaces.A dataset of LP-annotated images of vehicles was *** results of this study have considerable implications for smart parking,particularly in universities;in addition,they can be utilized for smart cities.

关键词： Parking LBP DL CNN license plate

Molecular mechanisms of the anti-obesity potential effect of Moringa oleifera in the experimental model

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Asian Pacific Journal of Tropical Biomedicine 2017年第3期7卷 214-221页

作者： Fateheya Mohamed Metwally Hend Mohamed Rashad Hanaa Hamdy Ahmed Asmaa Ahmed mahmoud Ehab Ragaa Abdol Raouf Aboelfetoh Mohamed abdalla Environmental and Occupational Medicine National Research CentreGizaEgypt Department of Hormones National Research CentreGizaEgypt Department of Zoology Faculty of ScienceAin Shams UniversityCairoEgypt Department of Research on Children with Special Needs National Research CentreGizaEgypt Department of Horticulture Crops Technology National Research CentreGizaEgypt

Objective: To elucidate the molecular mechanisms of the potent anti-obesity effect of Moringa oleifera Lam.(M. oleifera) ethanolic extract and to clarify the link between these mechanisms and the associated metabolic and vascular risks in the experimental model of visceral ***: M. oleifera ethanolic extract was orally administered at 600 mg/kg body weight in obese female rats daily for 12 weeks. At the end of treatment, body weight was determined, and the atherogenic index, coronary artery index, glucose level, insulin resistance status, liver and kidney functions were assessed. Also, the m RNA of leptin, adiponectin and resistin in visceral adipose tissue was determined by quantitative real ***: The results showed that M. oleifera extract down-regulated m RNA expression of leptin and resistin, while it up-regulated adiponectin gene expression in obese rats relative to untreated obese control counterparts. This amelioration of genes expression was paralleled by a reduction in body weight and improvement of the atherogenic index and coronary artery index, as well as glucose level and insulin resistance value without adverse effects on liver or kidney functions, versus the untreated obese control ***: It is reasonable to assume that the anti-obesity, anti-atherogenic and antidiabetic properties of M. oleifera are mechanistically achieved via working directly on the adipokines of the visceral adipose tissue. Therefore, M. oleifera may be a good therapeutic candidate for the symptoms of metabolic syndrome.

关键词： Moringa oleifera Lam Visceral adipose tissue Adipokines Gene expression Rats

New phase transitions for formulas in Lukasiewicz logic

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Frontiers of Computer Science 2020年第6期14卷 197-199页

作者： Mohamed EL HALABY Areeg abdalla Department of Mathematics Faculty of ScienceCairo UniversityGiza 12613Egypt

1 Introduction L-clausal forms is an interesting class of formulas in Eukasiewicz logic that was shown to be NP-complete[1].These formulas are defined over the following Lukasiewicz operations:negation-x=1-x strong di... 详细信息

关键词： formulas transitions Lukasiewicz

Gain and Emission Spectrum Characteristics of 465 nm Laser Diode Pumped Tm3+-Doped Telluride Glass Fibers

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Journal of Shanghai Jiaotong university(Science) 2017年第4期22卷 402-405页

作者： abdalla Saadelnour 姜淳 State Key Laboratory of Advanced Optical Communication Systems and Networks Shanghai Jiao Tong UniversityShanghai 200240China

Gain and emission spectrum characteristics of Tm3+-doped telluride glass fibers pumped with 465 nm lasers are analyzed. The rate and power propagation equation groups of the fibers are solved numerically and the effects of the fiber parameters including active ion concentration, length and pump power on the gain spectra and amplified spontaneous emission (ASE) spectra are analyzed. The results show that with a pump parameter of 465 nm/200mW, a doping concentration of 2.5×1025ion/m3and a fiber length of 16m, the gain and ASE spectra can cover from 1.100 to 1.900 μm, and the gain and ASE power peaks can reach 52 dB and 8mW, respectively. © 2017, Shanghai Jiaotong University and Springer-Verlag GmbH Germany.

关键词： gain thulium-doped tellurite glass fiber 465 nm pump laser

Serum resistin and the risk for hepatocellular carcinoma in diabetic patients

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World Journal of Gastroenterology 2023年第27期29卷 4271-4288页

作者： Mona Mohamed Ibrahim abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Hepatocellular carcinoma(HCC),the predominant type of liver cancer,is a major contributor to cancer-related fatalities across the *** has been identified as a significant risk factor for HCC,with recent research indicating that the hormone resistin could be involved in the onset and advancement of HCC in diabetic *** is a hormone that is known to be involved in inflammation and insulin *** with HCC have been observed to exhibit increased resistin levels,which could be correlated with more severe disease stages and unfavourable ***,the exact processes through which resistin influences the development and progression of HCC in diabetic patients remain *** article aims to examine the existing literature on the possible use of resistin levels as a biomarker for HCC development and ***,it reviews the possible pathways of HCC initiation due to elevated resistin and offers new perspectives on comprehending the fundamen-tal mechanisms of HCC in diabetic *** a better understanding of these processes may yield valuable insights into HCC’s development and progression,as well as identify possible avenues for prevention and therapy.

关键词： Hepatocellular carcinoma Resistin Insulin resistance Obesity Diabetes Liver cancer

Role of visfatin in obesity-induced insulin resistance

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World Journal of Clinical Cases 2022年第30期10卷 10840-10851页

作者： Mona Mohamed Ibrahim abdalla Physiology Department Human Biology DivisionSchool of MedicineInternational Medical UniversityKuala Lumpur 57000Bukit JalilMalaysia

The growing worldwide burden of insulin resistance(IR) emphasizes the importance of early identification for improved ***,particularly visceral obesity,has been a key contributing factor in the development of *** obesity-associated chronic inflammatory state contributes to the development of obesity-related comorbidities,including ***,which are released by adipose tissue,have been investigated as possible indicators of *** was one of the adipocytokines that attracted attention due to its insulinmimetic *** is released from a variety of sources,including visceral fat and macrophages,and it influences glucose metabolism and increases *** relationship between visfatin and IR in obesity is *** a result,the purpose of this review was to better understand the role of visfatin in glucose homeostasis and to review the literature on the association between visfatin levels and IR,cardiovascular diseases,and renal diseases in obesity.

关键词： Homeostatic model assessment for insulin resistance Insulin resistance Obesity Visfatin pre-B cell colony enhancing factor Nicotinamide phosphoribosyl-transferase enzyme Diabetes Adipocytokines

Enteric neuropathy in diabetes:Implications for gastrointestinal function

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World Journal of Gastroenterology 2024年第22期30卷 2852-2865页

作者： Mona Mohamed Ibrahim abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetes,commonly known for its metabolic effects,also critically affects the enteric nervous system(ENS),which is essential in regulating gastrointestinal(GI)motility,secretion,and *** development of diabetes-induced enteric neuropathy can lead to various GI dysfunctions,such as gastroparesis and irregular bowel habits,primarily due to disruptions in the function of neuronal and glial cells within the ENS,as well as oxidative stress and *** editorial explores the pathophysiological mechanisms underlying the development of enteric neuropathy in diabetic ***,it discusses the latest advances in diagnostic approaches,emphasizing the need for early detection and intervention to mitigate GI complications in diabetic *** editorial also reviews current and emerging therapeutic strategies,focusing on pharmacological treatments,dietary management,and potential neuromodulatory ***,this editorial highlights the necessity of a multidisciplinary approach in managing enteric neuropathy in diabetes,aiming to enhance patient quality of life and address a frequently overlooked complication of this widespread disease.

关键词： Diabetic neuropathy Gastrointestinal Insulin resistance Diabetes Enteric nervous system Enteric neuropathy

Advancing diabetes management: Exploring pancreatic beta-cell restoration’s potential and challenges

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World Journal of Gastroenterology 2024年第40期30卷 4339-4353页

作者： Mona Mohamed Ibrahim abdalla Department of Human Biology School of MedicineInternational Medical UniversityBukit Jalil 57000Kuala LumpurMalaysia

Diabetes mellitus,characterized by chronic hyperglycemia due to insulin deficiency or resistance,poses a significant global health *** to its pathogenesis is the dysfunction or loss of pancreatic beta cells,which are res-ponsible for insulin *** advances in beta-cell regeneration research offer promising strategies for diabetes treatment,aiming to restore endogenous insulin production and achieve glycemic *** review explores the physiological basis of beta-cell function,recent scientific advan-cements,and the challenges in translating these findings into clinical *** highlights key developments in stem cell therapy,gene editing technologies,and the identification of novel regenerative *** the potential,the field faces hurdles such as ensuring the safety and long-term efficacy of regen-erative therapies,ethical concerns around stem cell use,and the complexity of beta-cell differentiation and *** review highlights the importance of interdisciplinary collaboration,increased funding,the need for patient-centered approaches and the integration of new treatments into comprehensive care strategies to overcome these *** continued research and collab-oration,beta-cell regeneration holds the potential to revolutionize diabetes care,turning a chronic condition into a manageable or even curable disease.

关键词： Diabetes therapies Beta cell regeneration Regenerative medicine Stem cell therapy Gene editing Molecular therapeutics