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Schistosomiasis control in Senegal:results from community data analysis for optimizing preventive chemotherapy intervention with praziquantel

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Infectious Diseases of Poverty 2023年第6期12卷 101-102页

作者： Boubacar Diop Khadime Sylla NDèye MbackéKane Oumou Kaltoum Boh babacar Guèye mady ba Idrissa Talla Malang Mané Rose Monteil Boniface Kinvi Honorat Gustave Marie Zoure Jorge Cano Ortega Pauline Mwinzi Moussa Sacko babacar Faye Programme National de Lutte Contre les Bilharzioses et les Géo-Helminthiases Direction de la Lutte Contre la Maladie (DLM) Ministère de la Santé et de l’Action Sociale (MSAS) Dakar Senegal Department of Parasitology and Mycology Faculty of Medicine Pharmacy and Odontology Université Cheikh Anta Diop de Dakar (UCAD) Dakar Senegal WHO Country Office Dakar Senegal Département de Santé Publique Faculté des Sciences de la Santé Université Amadou Hampathé Ba Dakar Senegal FHI 360 Chargé des Enquêtes et Evaluation des Maladies et des Campagnes de DMM Dakar Senegal Expanded Special Project for Elimination of Neglected Tropical Diseases (ESPEN) WHO Africa Regional Office Brazzaville Congo Service de Parasitologie Institut National de Santé Publique (INSP) Bamako Mali

background Over the past two decades,preventive chemotherapy(PC)with praziquantel(PZQ)is the major strategy for controlling schistosomiasis in *** objective of this analysis was to update the endemicity of schistosomiasis at community level for better targeting mass treatment with PZQ in *** Demographic and epidemiological data from 1610 community health areas were analyzed using the schistosomiasis community data analysis tool of Expanded Special Project for Elimination of Neglected Tropical Diseases which developed by World Health Organization/Africa Ofce(WHO/AFRO).The tool uses a WHO/AFRO decision tree for areas without epidemiological data to determine whether mass treatment should be continued at community *** analysis was *** Overall,the endemicity of 1610 community health areas were updated based on the data from the district endemicity(33.5%)and the form of Join request for selected PC medicine(40.5%).Up to 282(17.5%)and 398(24.7%)of community health areas were classifed as moderate and high endemicity.41.1%of communities were non *** endemicity was more important in Tambacounda,Saint Louis,Matam,Louga and Kedougou.A change in endemicity category was observed when data was disagregted from district level to community *** units classifed non endemic were more important at community level(n=666)compared to district level(n=324).Among 540 areas previously classifed high endemic at district level,392(72.6%)remained high prevalence category,while 92(17.0%)became moderate,43(8.0%)low and 13(2.4%)non-endemics at community *** of implementation units requiring PC was more important at district level(1286)compared to community level(944).Number of school aged children requiring treatment was also more important at district level compared to community *** The analysis to disaggregate data from district level to community level using the WHO/AFRO schistosomiasis sub-distric

关键词： Schistosomiasis Community data analysis Endemicity Praziquantel Senegal

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Improving the Quality of baobab Oil by Filtration on Activated Carbon from the Fruit Capsules

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Journal of Materials Science and Chemical Engineering 2024年第1期12卷 69-83页

作者： Edouard Mbarick Ndiaye Alioune Sow Papa Guédel Faye Kalidou ba Mouhamed Ndoye Omar Ibn Khatab Cisse Nicolas Cyrille Ayessou mady Cisse Laboratory of Water Energy Environment and Industrial Processes (LE3PI) ESP-UCAD Dakar Senegal Laboratoire of Biological Agronomic Food Sciences and Modeling of Complex Systems (LABAAM) UFR of Agronomic Sciences Aquaculture and Food Technologies (S2ATA) Gaston Berger University of Saint-Louis Saint-Louis Senegal National School of Agriculture University Iba Der Thiam of Thiès Thiès Senegal Center of Studies on Food Security and Functional Molecules (CESAM-RESCIF) ESP-UCAD Dakar Senegal

The baobab, Adansonia digitata L., plays an important role in the economy of local populations. Nowadays, baobab seed oil is highly prized for its many cosmetic and therapeutic applications, and for its composition of unsaturated fatty acids, sterols, and tocopherols. However, it undergoes numerous reactions during production, processing, transport, and storage, leading to undesirable products that make it unstable. The aim of this study was to provide local processors with innovative solutions for the treatment of unrefined vegetable oils. To this end, an experimental device for filtering crude oil on activated carbon made from fruit capsules was designed. The results obtained after the treatment show a significant decrease at (p 2/Kg), chlorophyll concentration (1.81 to 0.50 mg/Kg) and primary and secondary oxidation products. According to these results, activated carbon’s adsorptive power eliminates oxidation products and certain pro-oxidants such as chlorophyll, resulting in a cleaner, more stable and better storable oil.

关键词： Activated Carbon Adansonia digitata L. baobab Fruit baobab Oil Stability

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Percutaneous Coronary Intervention in Acute Coronary Syndromes at the Mother-Child University Hospital Luxembourg in bamako

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World Journal of Cardiovascular Diseases 2024年第4期14卷 288-294页

作者： Mamadou Toure Hamma Sankare baba I. Diarra Mariam Dagnogo Modibo Doumbia Abdoul W. Terra Samba Sidibe Coumba A. Thiam Boubacar Sonfo Boubacar Diarra Asmaou Keita Ousmane Traore Daouda Fofana Almou A. Diall mady Sow Massama Konate Hamidou O. ba Ichaka Menta Cardiology Department CHU-Mother Child Bamako Mali Cardiology Department CHU-Gabriel Tour&#233 Bamako Mali Faculty of Medicine University of Sciences Techniques and Technologies of Bamako Bamako Mali Department of Cardiac Surgery Center Andre FESTOC Bamako Mali Cardiology Department CHU-Point G Bamako Mali

Introduction: Acute coronary syndromes (ACS) are a diagnostic and therapeutic emergency. Objective: Studying the feasibility, difficulties and results of coronary angioplasty in acute coronary syndromes at the Luxembourg Mother-Child University Hospital in bamako. Patients and Methods: Cross-sectional, descriptive study with prospective recruitment over 18 months from September 2020 to February 2022. All patients aged at least 18 years old admitted for SCA and having undergone PCI during the study period were included. Result: We collected 249 patients for SCA, of whom 160 underwent angioplasty, either an angioplasty/SCA ratio of 0.64. The average age of the patients was 59.54 ± 11.62 with extremes of 32 and 92 years. The age group of 45 to 65 years was the most representative. The predominance was male, sex ratio of 2.4. The main cardiovascular risk factors were high blood pressure (58.23%) and diabetes (45.78%). Persistent ST-segment elevation on the electrocardiogram was present in 71.48%. The treatment time was more than 12 hours after the first medical contact in 95.5%. The approach was radial in 96.5% of cases. Coronarography was pathological in 91.16% of our patients. The lesions were tri-truncular in 34.13% with the anterior inter ventricular as culprit artery in 72% of cases. The majority of patients (64%) had undergone angioplasty with implantation of an active stent. Angioplasty was performed successfully in 98% and per procedural mortality was 1.87%. Only 6.45% of ACS with ST elevation benefited from primary angioplasty. Conclusion: Percutaneous coronary intervention is performed routinely in our center with satisfactory results. Difficulties exist, related to the diagnostic delay of ACS and the high cost of angioplasty.

关键词： Acute Coronary Syndromes Coronary Angiography Angioplasty Mother-Child University Hospital Luxembourg bamako Mali

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Acute Coronary Syndrome of Young Subjects at the Luxembourg Mother-Child University Hospital in bamako

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World Journal of Cardiovascular Diseases 2024年第3期14卷 157-165页

作者： Mamadou Toure Mariam Dagnogo Massama Konate Mariam Sako Daouda Fofana Hamma Sankare Almou A. Diall Modibo Doumbia baba I. Diarr mady Sow Abdoul Wahhab Terra Coumba A. Thiam Boubacar Sonfo Boubacar Diarra Asmaou Keita Ousmane Traore Hamidou O. ba Ichaka Menta Cardiology Department CHU-Mother Child Bamako Mali Cardiology Department CHU-Gabriel Tour&#233 Bamako Mali Faculty of Medicine University of Sciences Technics and Technologies of Bamako Bamako Mali Center Andre FESTOC Department of Cardiac Surgery of Bamako Mali Bamako Mali

Introduction: Acute coronary syndrome is often the first event of coronary disease of young subjects. Objective: To study sociodemographic, clinical, paraclinical, therapeutic and evolutionary aspects of acute coronary syndrome of young subjects. Patients and Methods: Descriptive cross-sectional study with prospective recruitment from October 01, 2020 to March 31, 2022. Were included all patients admitted for acute coronary syndrome whose age was less or equal to 45 years and who had undergone coronary angiography at the Mother-Child University Hospital on Luxembourg from bamako. Results: During the study period, we collected 60 patient files out of 198. These 60 patient files met our inclusion criteria. Hospital frequency was 30.30%. Average age of patients was 40.43 ± 3.9 years. Sex ratio M/F was 5.3. Main cardiovascular risk factor was smoking tobacco (23.42%), followed by dyslipidemia (13.92%). Functional signs were dominated by angina 62% followed by dyspnea 25.3%. Persistent ST-segment elevation on electrocardiogram was present in 76.4%. Left ventricular systolic dysfunction was present in 26.5%. Time to first medical contact was more than 12 hours in 62.7% of cases. Radial approach was adopted in 94% of cases. Coronary angiography was pathological in 85% (n = 51) of cases. Lesions were single-vessel disease in 47.1% and culprit artery was anterior interventricular in 51% of cases. Dual anti-platelet aggregation was aspirin and ticagrelor in 91.8% of cases. Angioplasty was performed in all patients who had significant abnormalities at coronary angiography. In-hospital mortality was 3.9%. Conclusion: Acute coronary syndromes exist in young Africans with a male predominance. Main cardiovascular risk factor is smoking tobacco. Coronary lesions are single vessel disease in the majority of case. Most of patients meet medical team after 12 hours. Time to first medical contact is a main challenge in our country.

关键词： Acute Coronary Syndrome Young Subjects Coronary Angiography CHU Luxembourg bamako

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Processes for the Clarification of the Crude Oil of baobab Seeds Extracted by Pressing on Activated Carbon Elaborated from the Capsules of the Fruit (Adansonia digitata L.)

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Advances in Chemical Engineering and Science 2023年第2期13卷 105-118页

作者： Edouard Mbarick Ndiaye Alioune Sow Kalidou ba Mouhamed Ndoye Yousra El Idrissi Seyni Ndiaye Hamza El Moudden Papa Guedel Faye Hicham Harhar Nicolas Ayessou Mohamed Tabyaoui mady Cisse Laboratory of Water Energy Environment and Industrial Processes (LE3PI) ESP-UCAD ESP-UCAD Cheikh Anta Diop University Dakar Senegal Laboratory of Materials Nanotechnology and Environment Faculty of Sciences-Rabat Mohammed V University of Rabat Rabat Morocco Laboratory of Biological Agronomic Food Sciences and Modeling of Complex Systems (LABAAM) UFR of Agronomic Scienc-es Aquaculture and Food Technologies (S2ATA) Gaston Berger University of Saint-Louis Saint-Louis Senegal Higher School of Technology of El Kelaa of The Sraghna Cadi Ayyad University Marrakech Morocco

The baobab, Adansonia digitata L. plays an important role in the economy of local populations. The oil from the seeds of the baobab fruit is nowadays highly prized because of its numerous cosmetic and therapeutic applications and its composition of unsaturated fatty acids, sterols and tocopherols. However, unlike refined oils, locally extracted baobab oil has not undergone purification operations to ensure its quality. Only a filtration on special cloths is carried out after decantation. Indeed, the oil obtained after pressing is cloudy because of the presence of various impurities. It therefore requires treatment operations to make it more attractive and of higher quality. Therefore, in order to provide innovative solutions to local companies to improve the quality of vegetable oils, a study of clarification (treatment) of crude oil is necessary. An experimental device has been developed in the laboratory. It includes a glass column and a filter bed of dune sand and activated carbon. This study has shown the efficiency of the experimental device. Indeed, the activated carbon, thanks to its adsorbing power, has allowed a significant decrease in turbidity at the 5% threshold, from 14.61 NTU for the raw oil to 0.08 NTU for the oil filtered on 3% carbon and 0.033 NTU for the oil filtered on 5% carbon. That is to say an abatement higher than 95%. This decrease in turbidity could be correlated with the decrease in brown index from 187.39a for the initial crude oil to 128.53d for the oil treated with 3% activated carbon versus 187.59a for the oil filtered on cloths. The lowest brown index was observed with the filtration using 5% activated carbon (35.99b). Thus, for the yellowness index, only the filtration on 5% charcoal allowed to obtain a significant decrease in yellowness. The yellowing index of the oil with 5% was 44.67b against 79.04a for the oil filtered with 3% activated carbon, 86.33a fo

关键词： Activated Carbon baobab Oil Clarification Filtration Process

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Process Diagnosis and Aging Effects on a Traditional Millet-based Drink: <i>Boumkaye</i>

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Food and Nutrition Sciences 2018年第5期9卷 464-473页

作者： Oumar Ibn Khatab Cisse Nicolas Cyrille Ayessou Papa Guedel Faye mady Cisse Aida Coly Camara Aba Bodian Cheikh Ndiaye Mama Sakho Codou Mar Diop Ecole Supé rieure Polytechnique Cheikh Anta Diop University Dakar S&eacute né gal Centre d’Etudes sur la Sé curité Alimentaire et les Molé cules Fonctionnelles (CESAM) Dakar S&eacute né gal Entreprise AFbaRD Dakar S&eacute né gal Producteur de Boumkaye originaire de ba& amp la Dakar S&eacute né gal Institut de technologie alimentaire (ITA) Dakar S&eacute né gal

Boumkaye is a traditional fermented millet-based drink (Pennisetum glaucum L.) produced in Casamance (region in Senegal). Unknown and circumcised beverage, it has therapeutic properties due to aqueous creeper extracts from Abrus pulchellus plant and naturally present during the process. The objective of this work was to investigate the fabrication process of a millet-based beverage as an alternative source of nutrients. The diagnosis of beverage production by monitoring its physical and chemical parameters during two months of storage at room temperature was studied. The established manufacturing process, composed by a production of aqueous extracts after maceration of the Abrus pulchellus vines, a preparation of millet slurry, and a fermentation step to obtain the Boumkaye, has several features. The study of aging process showed probable lactic and alcoholic fermentations. Further, the finished Boumkaye was characterized by a high acidity (pH of 3), an alcohol content of 5 g/100g and contains an appreciable amount of polyphenols (54.46 mg/100g).

关键词： Pennisetum glaucum L. Abrus pulchellus Traditional Drinks Fermentation Boumkaye

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Valorization of Natural Residue into Activated Carbon:Example of the Shells of the African baobab Fruit(Adansonia digitata)L.

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材料科学与工程（中英文A版） 2022年第2期12卷 41-54页

作者： Edouard Mbarick Ndiaye Kalidou ba Alioune Sow Adama Diop Yousra El Idrissi Hamza El Moudden Papa Guedel Faye Hicham Harhar Nicolas Ayessou Mohamed Tabyaoui mady Cisse Laboratory of Water Energy Environment and Industrial Processes(LE3PI) ESP-UCADESP-UCADCheikh Anta Diop UniversityBP 5085DakarSenegal Laboratory of Biological AgronomicFood Sciences and Modeling of Complex Systems(LABAAM)UFR of Agronomic SciencesAquaculture and Food Technologies(S2ATA)Gaston Berger University of Saint-LouisNgallele RoadBP 234Saint-LouisSenegal Laboratory of Materials Nanotechnology and EnvironmentFaculty of Sciences-RabatMohammed V University of RabatBP 1014RabatMorocco Higher School of Technology of El Kelaa of the Sraghna Cadi Ayyad UniversityBP 104El Kelaa of the SraghnaMorocco

This study deals with the valorization of natural residues into activated carbon prepared from waste“baobab fruit shell”from the Fatick Region,***,after the preparation of the baobab shell,a chemical activation with orthophosphoric acid H3PO4(85%)was performed followed by pyrolysis at 530°*** eliminate possible carbonization residues,the activated carbons were impregnated in 0.1 M hydrochloric acid and/or soda solutions and then washed thoroughly with distilled water to obtain a pH between 6.5 and *** latter were then dried in an oven at 105°C for 24 h.A characterization was carried out to determine the moisture content,the ash content,the iodine and methylene blue indices,the surface functions and the pH at zero charge point(pHpzc).The moisture and ash contents were 1.87%and 0.72%,*** iodine and peroxide indices obtained were 939,09 mg/g and 575.73 mg/g,*** function analysis by Boehm’s method showed that the acidic functions were higher than the basic functions and their pHpzc was lower than *** best efficiency of methylene blue removal was 99.75%and was obtained with a mass of 0.150 g of activated carbon,pH equal to 10,an initial concentration of methylene blue of 200 mg/L and a contact time of 35 min.

关键词： Orthophosphoric acid activated carbon baobab fruit shell pyrolysis valorization

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