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Debaryomyces hansenii supplementation in low fish meal diets promotes growth,modulates microbiota and enhances intestinal condition in juvenile marine fish

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Journal of Animal Science and Biotechnology 2024年第1期15卷 253-276页

作者： Ignasi Sanahuja Alberto Ruiz Joana P.Firmino Felipe E.Reyes-López Juan B.Ortiz-delgado Eva Vallejos-Vidal Lluis Tort Dariel Tovar-Ramírez Isabel M.Cerezo Miguel A.Moriñigo carmen Sarasquete Enric Gisbert Aquaculture Program Institute of Agrifood Research and Technology(IRTA)La Rapita 43540Spain Centro de Biotecnologia Acuicola Universidad de Santiago de ChileSantiagoChile Instituto de Ciencias marinas de Andalucia(ICmaN-CSIC) Avda.Republica Saharaui no 2Campus Universitario Rio San PedroPuerto RealCadiz 11510Spain Nucleo de Investigaciones Aplicadas en Ciencias Veterinarias y Agronomicas Facultad de Medicina Veterinaria y AgronomiaUniversidad de Las AmericasSantiagoChile Department of Cell Biology Physiologyand ImmunologyUniversitat Autonoma de BarcelonaBarcelonaSpain Centro de Investigaciones Biologicas del Noroeste SC CIBNORLa PazMexico Department of Microbiology Instituto de Biotecnologia Y Desarrollo Azul(IBYDA)Faculty of SciencesUniversity of Malaga29010 MalagaSpain SCBI Bioinformatic UnitUniversity of Malaga29590 MalagaSpain

Background The development of a sustainable business model with social acceptance,makes necessary to develop new strategies to guarantee the growth,health,and well-being of farmed *** hansenii is a yeast species that can be used as a probiotic in aquaculture due to its capacity to i)promote cell proliferation and differen-tiation,ii)have immunostimulatory effects,iii)modulate gut microbiota,and/or iv)enhance the digestive *** provide inside into the effects of *** on juveniles of gilthead seabream(Sparus aurata)condition,we inte-grated the evaluation of the main key performance indicators coupled with the integrative analysis of the intestine condition,through histological and microbiota state,and its transcriptomic *** After 70 days of a nutritional trial in which a diet with low levels of fishmeal(7%)was supplemented with 1.1%of ***(17.2×10^(5) CFU),an increase of ca.12%in somatic growth was observed together with an improve-ment in feed conversion in fish fed a yeast-supplemented *** terms of intestinal condition,this probiotic modu-lated gut microbiota without affecting the intestine cell organization,whereas an increase in the staining intensity of mucins rich in carboxylated and weakly sulphated glycoconjugates coupled with changes in the affinity for certain lectins were noted in goblet *** in microbiota were characterized by the reduction in abundance of several groups of Proteobacteria,especially those characterized as opportunistic *** microarrays-based transcrip-tomic analysis found 232 differential expressed genes in the anterior-mid intestine of ***,that were mostly related to metabolic,antioxidant,immune,and symbiotic *** Dietary administration of *** enhanced somatic growth and improved feed efficiency param-eters,results that were coupled to an improvement of intestinal condition as histochemical and transcriptomic tools *** probiotic ye

关键词： Debaryomyces hansenii Intestine condition Low fish meal diet Microbiota Transcriptomics Yeast probiotic

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Morphometrics confirms the conspecific between Blaptica dubia(Serville) and B. interior Hebard(Blattodea:Blaberidae)

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Zoological Systematics 2019年第2期44卷 111-122页

作者： maría marta.gonzález Alejandra del carmen Valverde Mónica Sandra Iglesias Francisco Antonio Crespo Laboratorio de Artrópodos Departamento de Biodiversidad y Biología Experimental Facultad de Ciencias Exactas y Naturales Universidad de Buenos Aires Pabellón Ⅱ Ciudad Universitaria Centro de diagnóstico e investigación en endemo-epidemias. Administración nacional de laboratorios e institutos de salud "Dr. Carlos G. malbrán"

Blaptica dubia(Serville, 1838) and B. interior Hebard, 1921 were considered to be cryptic species. The characteristics originally proposed for their identification are not *** the relationship between the two species should be re-considered. As a comparative approach and to analyze intraspecific variability, morphological and morphometric methods were performed. Traditional and new characters such as wing shape and pronotum contour were utilized. We found significant differences between both species(p male genitalia or the pronotal *** on the obtained results, B. interior Hebard 1921 is considered to be a junior synonym of B. dubia(Serville, 1838).

关键词： Cockroaches pronotum genitalia geometric morphometric analysis synonymy

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Reduction of the closure time of postoperative enterocutaneous fistulas with fibrin sealant

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World Journal of Gastroenterology 2010年第22期16卷 2793-2800页

作者： Jorge Avalos-gonzález Eliseo Portilla-deBuen Caridad Aurea Leal-Cortés Abel Orozco-Mosqueda maría del carmen Estrada-Aguilar Gabriela Abigail Velázquez-Ramírez Gabriela Ambriz-gonzález Clotilde Fuentes-Orozco Aldo Emmerson Guzmán-Gurrola Alejandro gonzález-Ojeda Research Unit in Clinical Epidemiology High Specialized Medical Unit Surgical Research Division National Western Medical Center Department of Surgery Regional General Hospital #1 of the Mexican Institute for Social Security Avenida Héroes de Nocupetaro y Nicolás de Regules Colonia Centro Department of Pediatric Surgery Children's Hospital National Western Medical Center

AIM: To assess whether the use of fibrin sealantshortens the closure time of postoperative enterocutaneous fistulas (ECFs). METHODS: The prospective case-control study included 70 patients with postoperative ECFs with an output of 2 cm and without any local complication. They were divided into study (n = 23) and control groups (n = 47). Esophageal, gastric and colocutaneous fistulas were monitored under endoscopic visualization, which also allowed fibrin glue application directly through the external hole. Outcome variables included closure time, time to resume oral feeding and morbidity related to nutritional support. RESULTS: There were no differences in mean age, fistula output, and follow-up. Closure-time for all patients of the study group was 12.5 ± 14.2 d and 32.5 ± 17.9 d for the control group (P ch group died during follow-up as a consequence of septic complications related to parenteral nutrition. CONCLUSION: Closure time was significantly reduced with the use of fibrin sealant, and oral feeding was resumed faster. We suggest the use of fibrin sealant for the management of stable enterocutaneous fistulas.

关键词： Enterocutaneous fistulas Fibrin sealant Spontaneous closure

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The Iberian Roma Population Variant Server(IRPVS)

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Journal of Genetics and Genomics 2024年第7期51卷 769-773页

作者： Fabiola mavillard Javier Perez-Florido Francisco M.Ortuño Amador Valladares Miren L.Álvarez-Villegas Gema Roldán Rosario Carmona manuel Soriano Santiago Susarte Pilar Fuentes Daniel López-López Ana maría Nuñez-Negrillo Alejandra Carvajal Yolanda Morgado Daniel Arteaga Rosa Ufano Pablo Mir Juan F.Gamella Joaquín Dopazo carmen Paradas macarena Cabrera-Serrano Instituto de Biomedicina de Sevilla(IBiS) Hospital Universitario Virgen del Rocío/CSIC/Universidad de SevillaSevillaSpain Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas(CIBERNED) Instituto de Salud CarlosⅢSevillaSpain Plataforma Andaluza de Medicina Computacional Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevillaSpain Grupo de medicina computacional de sistemas Instituto de Biomedicina de Sevilla(IBiS)Hospital Virgen del RocíoSevillaSpain Nodo de Genómica Funcional (INB-ELIXIR-es)Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevilla 41013Spain Bioinformática en Enfermedades raras(BiER) Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER)Instituto de salud CarlosⅢSevillaSpain Departamento de Ingeniería de Computadores Automática y RobóticaUniversidad de GranadaGranadaSpain Servicio de Urgencias de Atención Primaria Distrito SevillaSevillaSpain Centro de Servicios Sociales Negociado de Servicios EspecializadosAyuntamiento de SevillaSevillaSpain Departamento de Enfermería Facultad de Ciencias de la SaludUniversidad de GranadaGranadaSpain Departamento de Neurología Hospital Virgen de las NievesGranadaSpain Departamento de Neurología Hospital Virgen de ValmeSevillaSpain Centro de Salud Utrera Sur SevillaSpain Centro de Salud Polígono Sur SevillaSpain Unidad de Trastornos del Movimiento Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain Departamento de Medicina Facultad de MedicinaUniversidad de SevillaSevilleSpain Departamento de Antropología Social Universidad de GranadaSpain Unidad Enfermedades Neuromusculares Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain

In recent years,the number of known disease genes has exponentially grown due to the widespread adoption of cost-effective massive parallel *** identify new disease variants,especially in monogenic disorders,a frequen... 详细信息

关键词： Server filtering massive

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Effect of Zn, Cd and Cr on growth, water status and chlorophyll content of barley plants (<i>H. vulgare L.</i>)

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Agricultural Sciences 2012年第4期3卷 572-581页

作者： águeda.gonzález Valerio chumillas maría del carmen Lobo Dpto. de Investigación Agroambiental CAM Apdo. 127 28800 Alcalá de Henares (Madrid) Spain

To evaluate the potential of barley for the phytoremediation of soils contaminated by metals, we conducted a growth chamber experiment with plants exposed to various concentrations of Zn, Cd and Cr. Growth parameters, chlorophyll content and chlorophyll fluorescence were measured at 15 and 29 days after treatment application, and the metal concentration in the aerial part of the plant, the root and the soil was also measured. In all cases, the amount of metal accumulated in the plant increased by increasing the concentration of the applied metal, and the roots accumulated more metal than did the aerial part of the plant. The amount of Cr found in the soil was significantly lower than that of Cd and Zn. The toxic effect of Zn and Cd on the plant was low, affecting growth only at the highest concentrations. For Zn and Cd at the concentrations used, the decrease in water content was 14% compared with the control and 26% for Cr. For plants treated with the highest metal concentrations, the most significant differences were found in chlorophyll content, which had the lowest values compared with the control (23% for Zn, and 42% for Cd and Cr), and in chlorophyll fluorescence (2% for Zn, 23% for Cd and 29% for Cr). These decreases occurred 29 days after applying the Zn and Cd treatments. In plants treated with Cr, the decrease occurred 15 days after treatment application. Under our experimental conditions, barley is more tolerant to Zn and Cd than to Cr.

关键词： Heavy Metal Growth chlorophyll Fluorescence chlorophyll Content Barley

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Gingival enlargement induced by cyclosporine in Medullary aplasia:A case report

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World Journal of Clinical Cases 2022年第34期10卷 12750-12760页

作者： Giovanna Victory Rodríguez Alondra del carmen Ruiz Gutiérrez Juan Ramón Gómez Sandoval Sarah Monserrat Lomelímartínez Periodontics Program Department of Integrated Dentistry ClinicsCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico Research Institute of Dentistry Department of Integrated Dentistry ClinicsCentro Universitario de Ciencias de la SaludUniversidad de GuadalajaraGuadalajara 44340JaliscoMexico Department of Medical and Life Sciences Centro Universitario de la CiénegaUniversidad de GuadalajaraOcotlán 47810JaliscoMexico

BACKGROUND Cyclosporine is an immunosuppressive agent used effectively for treatment of a rare haematological disorder known as medullary *** drug prevents several side effects,including gingival enlargement(GE)which compromises aesthetics,phonetics and chewing,and also predisposes patients to *** SUMmaRY This clinical case reports a 41-year-old woman who presented with cyclosporineinduced GE with underlying periodontitis and medullary *** management of the disease was approached through multidisciplinary strategy which allowed for accurate diagnosis and a strategic treatment based on the systemic condition and severity of oral *** diagnosis was confirmed through histopathological *** treatment was carried out in phases:Initial(oral hygiene motivation,mechanical supragingival plaque control,and non-surgical therapy);systemic treatment,corrective treatment,and *** Multidisciplinary management of cyclosporine-induced GE and medullary aplasia allows for correct diagnosis and effective treatment of this pathological expression through a phased therapeutic approach.

关键词： Cyclosporine Gingival enlargement Medullary aplasia Periodontal surgery Case report

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Effectiveness of sacubitril-varsartan versus angiotensin converting enzyme inhibitors in patients hospitalized for acute heart failure:a retrospective cohort study of the RICA registry

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Journal of Geriatric Cardiology 2022年第11期19卷 802-810页

作者： Llanos Soler-Rangel manuel Méndez-Bailón JoséPérez-Silvestre Josémaría Fernández-Rodríguez Beatriz Cuesta García Adrián Argüelles-Curto Álvaro gonzález-Franco Alicia Conde-martel Sara Carrascosa-García marta Sánchez-marteles Josémanuel Cerqueiro-gonzález Noel Lorenzo-Villalba manuel Montero-Pérez-Barquero Llanos Soler-Rangel Servicio de Medicina InternaHospital Universitario Infanta SofíaFIIB HUIS HHENMadridSpain Servicio de Medicina Interna Hospital Clínico San CarlosInstituto de Investigación San Carlos(IdISSC)Spain Servicio de Medicina Interna Consorcio Hospital General Universitario de ValenciaSpain Servicio de Medicina Interna Hospital Carmen y Severo OchoaCangas del NarceaAsturiasSpain Servicio de Medicina Interna Hospital Universitario Central de AsturiasOviedoSpain Servicio de Medicina Interna Hospital Universitario de Gran Canaria Dr NegrínSpain Servicio de Medicina Interna Hospital Clínico Universitario Lozano Blesa de ZaragozaZaragozaSpain Hospital Universitario Lucus Augusti de Lugo LugoSpain Service de Médecine Interne Diabète et Maladies MétaboliquesHôpitaux Universitaires de StrasbourgFrance Servicio de Medicina Interna IMIBIC/Hospital Universitario Reina SofíaCórdobaSpain

BACKGROUND Sacubitril-valsartan has been shown to reduce hospitalizations and mortality in patients with heart failure(HF)and reduced ejection *** PIONEER-HF trial demonstrated that initiation of the drug during acute HF hospitalization reduced NT-proBNP levels and a post-hoc analysis of the trial found a reduction in HF hospitalizations and ***-life studies in the elderly population are *** aim of our study was to assess the effectiveness of sacubitril-valsartan versus angiotensin converting enzyme inhibitors(ACEI)in elderly patients who initiate this treatment during hospitalization for acute *** We conducted a retrospective cohort study using the Spanish acute heart failure registry(RICA)comparing rehospitalizations and deaths at 3 months and 1 year among patients aged 70 years or older who had initiated treatment with sacubitrilvalsartan during hospitalization for acute HF versus those treated with *** One hundred and ninety-nine patients hospitalized between October 2016 and November 2020 were included,with a median age of 82 years and high rate of *** these,107 were treated with sacubitril-valsartan and 92 with *** adjusted OR for readmission for HF at 3 months was 0.906(95%CI:0.241-3.404)and for the combined variable readmission for HF or death at 3 months was 0.696(95%CI:0.224-2.167).The adjusted OR for HF readmission at one year was 0.696(95%CI:0.224-2.167).and for the combined variable HF readmission or death at one year 0.724(95%CI:0.325-1.612).CONCLUSION Treatment with sacubitril-valsartan initiated early in hospitalization for HF in elderly patients with high comorbidity was associated with a trend towards a reduction in readmissions and death due to HF compared to treatment with ACEI,which did not reach statistical significance either at 3 months or 1 year of follow-up.

关键词： patients initiated admission

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Laser trimming for lithography-free fabrications of MoS_(2)devices

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Nano Research 2023年第4期16卷 5042-5046页

作者： Yong Xie OnurÇakıroğlu Wenshuai Hu Kexin He Sergio Puebla Thomas Pucher Qinghua Zhao Xiaohua ma carmen Munuera Andres Castellanos-Gomez Key Laboratory of Wide Band-Gap Semiconductor Technology School of Advanced Materials and NanotechnologyXidian UniversityXi’an 710071China materials Science Factory Instituto de Ciencia de Materiales de MadridConsejo Superior de Investigaciones Científicas28049 MadridSpain

Single-layer MoS_(2)produced by mechanical exfoliation is usually connected to thicker and multilayer *** show a facile laser trimming method to insulate single-layer MoS_(2)regions from thicker *** demonstrate,through electrical characterization,that the laser trimming method can be used to pattern single-layer MoS_(2)channels with regular geometry and electrically disconnected from the thicker *** photocurrent microscope further confirms that in the as-deposited flake(connected to a multilayer area)most of the photocurrent is being generated in the thicker flake *** laser trimming,scanning photocurrent microscopy shows how only the single-layer MoS_(2)region contributes to the photocurrent *** presented method is a direct-write and lithography-free(no need of resist or wet chemicals)alternative to reactive ion etching process to pattern the flakes that can be easily adopted by many research groups fabricating devices with MoS_(2) and similar twodimensional materials.

关键词： 2D materials transition metal dichalcogenides laser trimming differential reflectance

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Temporal dynamics of shallow subtidal meiobenthos from a beach in Tenerife (Canary Islands, northeast Atlantic Ocean)

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Acta Oceanologica Sinica 2013年第8期32卷 44-54页

作者： Rodrigo Riera Jorge Núez maría del carmen Brito Centro de Investigaciones Medioambientales del Atlántico (CIma SL) Arzobispo Elías Yanes 4438206 La Laguna Tenerife Canary Islands Spain Benthos Laboratory Department of Animal Biology Faculty of Biology University of La Laguna

A shallow subtidal （3 m deep） meiofaunal assemblage in Los Abrigos Bay, Tenerife, Canary Islands was sam- pled during may 2000-April 2001. The main aims were to （1） find temporal variations in meiofaunal assem- blage structure and overall abundance, as well as in the most abundant meiofaunal species throughout the study period, and （2） identify environmental variables （sedimentary composition, organic matter content, and total nitrogen） that better explain meiofaunal assemblage structure during the study year. The most abundant species were the nematodes Siphonolaimus sp. 2 and Catanema sp., which represented 46.2% of the overall meiofaunal abundances and varied significantly throughout the study duration. Overall meio- faunal abundance and the most abundant taxonomic groups （nematodes, copepods, and oligochaetes） showed significant temporal variations during the study period. Nematodes overwhelmingly dominated during the study period, ranging from 78% in may to 97.34% in February. Multivariate analyses showed seasonality in meiofaunal community structure during the study year, with the lowest abundances in may. Keywords： Meiofauna, assemblage structure, subtidal, Canary Islands, Atlantic Ocean

关键词： Meiofauna assemblage structure subtidal Canary Islands Atlantic Ocean

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QualiTeam: A Support Tool When Learning Software Quality and Testing Concepts

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Journal of Software Engineering and Applications 2022年第1期15卷 1-17页

作者： Jorge Cervantes-Ojeda maría del carmen Gómez-Fuentes Department of Applied mathematics and Systems Universidad Autónoma Metropolitana Mexico City Mexico

QualiTeam is a web application to support the teaching-learning process on Software Quality Assurance, Quality Control and Testing introductory concepts. It has two main objectives: to facilitate the understanding of concepts learned in theory and to facilitate the monitoring of SW projects that students develop. The system gives the teacher control and the students a guide on the activities that must be carried out throughout a software project development. QualiTeam is a tool conceived to help in the challenge of providing students with concrete examples with which they can practice and clarify the topics taught in the classroom. With it, students can apply concepts that, in the initial training of a software engineer, are generally taught only at a theoretical level such as: review process, change requests, trouble reports, document version control and testing documentation management. QualiTeam is free and available online. It has been in operation for 5 years, through which improvements have been made until achieving a quite stable version.

关键词： Software Engineering Education Review Process Testing Documentation Teaching of SW Quality Assurance

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