检索结果-南通市图书馆

The In-Flight Realtime Trigger and Localization Software of GECAM

Research in Astronomy and Astrophysics 2024年第10期24卷 11-24页

作者： xiao-yun zhao Shao-lin Xiong Xiang-Yang wen Xin-Qiao li Ce Cai Shuo xiao Qi Luo wen-Xi Peng Dong-Ya guo zheng-hua An Ke Gong Jin-yuan liao Yan-Qiu Zhang yue huang Lu li Xing wen fei Zhang Jing Duan Chen-Wei Wang Dong-li Shi Peng Zhang Qi-Bin Yi Chao-Yang li Yan-Bing Xu xiao-hua liang Ya-Qing liu Da-li Zhang Xi-Lei Sun Fan Zhang gang Chen huan-yu Wang Sheng Yang xiao-Jing liu Min Gao mao-Shun li Jin-zhou Wang Xing zhou Yi zhao Wang-Chen Xue Chao zheng jia-Cong liu Xing-Bo Han Jin-ling Qi jia huang Ke-Ke Zhang Can Chen Xiong-Tao Yang Dong-Jie Hou yu-Sa Wang Rui Qiao Xiang ma xiao-Bo li Ping Wang Xin-Ying Song li-Ming Song Shi-Jie zheng Bing li Hong-mei Zhang yue Zhu Wei Chen jian-jian he zhen Zhang Jin Hou Hong-Jun Wang Yan-Chao Hao Xiang-yu Wang Zong-yuan Yang Zhi-Long wen Zhi Chang yuan-yuan Du Rui Gao xiao-fei Lan Yan-guo li gang li Xu-Fang li Fang-Jun Lu Hong Lu Bin Meng Feng Shi hui Wang hui-zhen Wang yu-Peng Xu jia-Wei Yang Xue-juan Yang Shuang-Nan Zhang Chao-yue Zhang Cheng-Mo Zhang Zhi-Cheng Tang Cheng Cheng Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China School of Information Science and Technology Southwest Jiaotong UniversityChengdu 611756China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Physics and Space Science College China West Normal UniversityNanchong 637002China Department of Astronomy Beijing Normal UniversityBeijing 100875China Innovation Academy for Microsatellites of CAS Shanghai 201203China Changchun University of Science and Technology Changchun 130022China Chinese Academy of Sciences South America Center for Astronomy National Astronomical ObservatoriesCASBeijing 100101China

Realtime trigger and localization of bursts are the key functions of GECAM,an all-sky gamma-ray monitor launched on 2020 December *** developed a multifunctional trigger and localization software operating in the CPU of the GECAM Electronic *** onboard software has the following features:high trigger efficiency for real celestial bursts with a suppression of false triggers caused by charged particle bursts and background fluctuation,dedicated localization algorithm optimized for both short and long bursts,and low time latency of the trigger information which is downlinked through the Global Short Message Communication service of the global BeiDou navigation *** paper provides a detailed description of the design and development of the trigger and localization software system for *** covers the general design,workflow,the main functions,and the algorithms used in the *** paper also includes on-ground trigger tests using simulated gamma-ray bursts generated by a dedicated X-ray tube,as well as an overview of the performance for real celestial bursts during its in-orbit operation.

关键词： telescopes instrumentation:detectors methods:observational

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Overexpression of γ-aminobutyric acid transporter subtype I leads to susceptibility to Kainic acid-induced seizure in transgenic mice

引用

Cell Research 2001年第1期11卷 61-67页

作者： ma yinghua, jia hua hu, wen juan zhao, jian fei, yun yu, xiao gang zhou, zhen tong mei, li he guo (institute of Biochemistry and Cell Biology, shanghai institutes for Biological Sciences, Chinese Academy of Sciences, shanghai 200031, China) (shanghai inst institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Sciences Shanghai China shanghai institute of Physiology Chinese Academy of Sciences Shanghai China

γ-aminobutyric acid (GABA) is the principal inhibitory neurotransmitter, and the GABAergic synaptic transmission is normally terminated by the rapid uptake through GABA transporters. With transgenic mice ubiquitously overexpressing GABA transporter subtype I (GAT1), the present study explored the pathophysiological role of GAT1 in epileptogenesis. Though displaying no spontaneous seizure activity, these mice exhibit altered electroencephalographic patterns and increased susceptibility to seizure induced by kainic acid. In addition, the GABAA receptor and glutamate transporters are up-regulated in transgenic mice, which perhaps reflects a compensatory or corrective change to the elevated level of GAT1. These preliminary findings support the hypothesis that excitatory and inhibitory neurotransmission, and seizure susceptibility can be altered by neurotransmitter transporters.

关键词： γ-aminobutyric acid transporter seizure susceptibility kainic acid electroencephalography transgenic mice

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

γ-Aminobutyric acid transporter (GAT1) overexpression in mouse affects the testicular morphology

引用

Cell Research 2000年第1期10卷 59-69页

作者： ma YING hua jia hua hu xiao gang zhou zhen tong mei jian fei li he guo(shanghai institute of Cell Biology, Chinese Academy of Science, shanghai 200031, China shanghai institute of Physiology, Chinese Academy of Science, shanghai 200031, China) shanghai institute of Cell Biology Chinese Academy of Science Shanghai China shanghai institute of Physiology Chinese Academy of Science Shanghai China

γ-Aminobutyric acid and GABAergic receptors were previously reported to be distributed in reproductive systems besides CNS and predicted to participate in the modulation of testicular function. γ-Aminobutyric acid transporter was implicated to be involved in this process. However, the potential role of γ-aminobutyric transporter in testis has not been explored. In this study, we investigated the existence of mouse γ-aminobutyric acid transporter subtype I (mGAT1) in testis. Wild-type and transgenic mice, which overexpressing mGAT1 in a variety of tissues, especially in testis, were primarily studied to approach the profile of mGAT1 in testis. Mice with overexpressed mGAT1 develop normally but with reduced mass and size of testis as compared with wild-type. Testicular morphology of transgenic mice exhibited overt abnormalities including focal damage of the spermatogenic epithelium accompanied by capillaries proliferation and increased diameter of seminiferous tubules lumen. Reduced number of spermatids was also found in some seminiferous tubules. Our results clearly demonstrate the presence of GAT1 in mouse testis and imply that GAT1 is possibly involved in testicular function.

关键词： γ-aminobutyric acid transporter testicular morphology mouse.

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Transgenic mice overexpressingγ-aminobutyric acid transporter subtypeⅠ develop obesity

引用

Cell Research 2000年第4期10卷 303-310页

作者： ma YING hua jia hua hu xiao gang zhou RUO WANG ZENG zhen tong mei jian fei li he guo institute of Biochemistry and Cell Biology, shanghai institutes for Biological Sciences, Chinese Academy of Science, shanghai 200031, China shanghai institute of institute of Biochemistry and Cell Biology Shanghai Institutes for Biological Sciences Chinese Academy of Science Shanghai China shanghai institute of Physiology Chinese Academy of Science Shanghai China

Transgenic mice ubiquitously overexpressing murine γ aminobutyric acid transporter subtype Ⅰ were created. Unexpectedly, these mice markedly exhibited heritable obesity, which features significantly increased body weight and fat deposition. Behavioral examination revealed that transgeinc mice have slightly reduced spontaneous locomotive capacity and altered feeding pattern. Tills preliminary finding indicates that the inappropriate level of γ-aminobutyric acid transporters may be directly or indirectly involved in the pathogenic mechanism underlying certain types of obesity.

关键词： γ-aminobutyric acid transporter subtype Ⅰ transgenic mouse obesit€

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

CEPC Technical Design Report

引用

Radiation Detection Technology and Methods 2024年第1期8卷 I0003-I0016,1-1091页

作者： Waleed Abdallah Tiago Carlos Adorno de Freitas Konstantin Afanaciev Shakeel Ahmad Ijaz Ahmed xiaocong Ai Abid Aleem Wolfgang Altmannshofer Fabio Alves Weiming An Rui An Daniele Paolo Anderle Stefan Antusch Yasuo Arai Andrej Arbuzov Abdesslam Arhrib Mustafa Ashry Sha Bai yu Bai Yang Bai Vipul Bairathi Csaba Balazs Philip Bambade Yong Ban Tripamo Bandyopadhyay Shou-Shan Bao Desmond P.Barber Ayse Bat Varvara Batozskaya Subash Chandra Behera Alexander Belyaev Michele Bertucci xiao-Jun Bi yuanjie Bi Tianjian Bian Fabrizio Bianchi Thomas Biekotter Michela Biglietti Shalva Bilanishvili Deng Binglin Denis Bodrov Anton Bogomyagkov Serge Bondarenko Stewart Boogert maarten Boonekamp marcello Borri Angelo Bosotti Vincent Boudry Mohammed Boukidi Igor Boyko Ivanka Bozovic Giuseppe Bozzi Jean-Claude Brient Anastasiia Budzinskaya masroor Bukhari Vladimir Bytev Giacomo Cacciapaglia hua Cai wenyong Cai Wujun Cai Yijian Cai Yizhou Cai yuchen Cai Haiying Cai huacheng Cai Lorenzo Calibbi Junsong Cang guofu Cao jianshe Cao Antoine Chance Xuejun Chang yue Chang Zhe Chang Xinyuan Chang Wei Chao Auttakit Chatrabhuti Yimin Che yuzhi Che Bin Chen Danping Chen Fuqing Chen Fusan Chen gang Chen guoming Chen hua-Xing Chen huirun Chen Jinhui Chen Ji-yuan Chen Kai Chen mali Chen Mingjun Chen Mingshui Chen Ning Chen Shanhong Chen Shanzhen Chen Shao-Long Chen Shaomin Chen Shiqiang Chen Tianlu Chen Wei Chen Xiang Chen xiaoyu Chen Xin Chen Xun Chen Xurong Chen Ye Chen Ying Chen yukai Chen Zelin Chen Zilin Chen gang Chen Boping Chen Chunhui Chen Hok Chuen Cheng huajie Cheng Shan Cheng tongguang Cheng yunlong Chi Pietro Chimenti wen Han Chiu Guk Cho Ming-Chung Chu xiaotong Chu Ziliang Chu Guglielmo Coloretti Andreas Crivellin Hanhua Cui xiaohao Cui zhaoyuan Cui Brunella D'Anzi ling-yun Dai Xinchen Dai Xuwen Dai Antonio De maria Nicola De Filippis Christophe De La Taille Francesca De Mori Chiara De Sio Elisa Del Core Shuangxue Deng Wei-Tian Deng Zhi Deng Ziyan Deng Bhupal Dev Tang Dewen Biagio Di Micco Ran Ding Siqin Dingl Yadong Ding Haiyi Dong jianin AGH University of Science and Technology Faculty of Physics and Applied Computer ScienceKrakow Anhui University HefeiAnhui Applied Physics Department Federal Urdu University of ArtsScience and TechnologyIslamabad Banaras Hindu University Institute of ScienceVaranasi Bandirma Onyedi Eylul University Bandirma Beihang University Beijing Beijing Computational Science Research Center Beijing Beijing Conveyi LTD Beijing Beijing Glass Research institute Co. LtdBeijing Beijing institute of Technology Beijing Beijing Normal University Beijing Brown University ProvidenceRI Budker institute of Nuclear Physics Novosibirsk Cadi Ayyad University Laboratory of Fundamental and Applied PhysicsPolydisciplinary FacultyMarrakech Cairo University Giza Center for Theory and Computation National Tsing Hua UniversityHsinchu Central China Normal University WuhanHubei Central South University ChangshaHunan Centro de Fisica Teorica de Particulas Universidade Tecnica de LisboaLisboa Chengdu KaitengSifang Digital Radio&TV Equipment Co. LtdChengduSichuan China academy of engineering physics MianyangSichuan China building materials academy Beijing China Center of Advanced Science and Technology Beijing China institute of Atomic Energy Beijing China Jiliang University HangzhouZhejiang China Nuclear instrument CO. LTDBeijing China University of Geosciences Beijing China University of Geosciences WuhanHubei China University of Mining and Technology XuzhouJiangsu China West Normal University NanchongSichuan Chongqing University Department of PhysicsChongqing Chulalongkorn University Bangkok City University of Hong Kong Department of PhysicsHong Kong Cockcroft institute Daresbury Cornell University IthacaNY CPPM(AMU/IPhu&CNRS/INP) Marseille Dalian Minzu University DalianLiaoning Dalian University of Technology Department of PhysicsDalian Deutsches Elektronen-Synchrotron DESY Hamburg Dzhelepov Laboratory of Nuclear Problems of Joint institute for Nuclear Research(DLNP JINR) Dubna East China University Of Science And Technol

The Circular Electron Positron Collider(CEPC)is a large scientific project initiated and hosted by China,fostered through extensive collaboration with international *** complex comprises four accelerators:a 30 GeV linac,a 1.1 GeV Damping Ring,a Booster capable of achieving energies up to 180 GeV,and a Collider operating at varying energy modes(Z,W,H,and tt).The linac and Damping Ring are situated on the surface,while the subterranean Booster and Collider are housed in a 100 km circumference underground tunnel,strategically accommodating future expansion with provisions for a potential Super Proton Proton Collider(SPPC).The CEPC primarily serves as a Higgs *** its baseline design with synchrotron radiation(SR)power of 30 MW per beam,it can achieve a luminosity of 5×10^(34)cm^(-2)s^(-1)per interaction point(IP),resulting in an integrated luminosity of 13 ab^(-1)for two IPs over a decade,producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC's capability to generate 4.3 million Higgs bosons,facilitating precise measurements of Higgs coupling at sub-percent levels,exceeding the precision expected from the HL-LHC by an order of *** Technical Design Report(TDR)follows the Preliminary Conceptual Design Report(Pre-CDR,2015)and the Conceptual Design Report(CDR,2018),comprehensively detailing the machine's layout,performance metrics,physical design and analysis,technical systems design,R&D and prototyping efforts,and associated civil engineering ***,it includes a cost estimate and a preliminary construction timeline,establishing a framework for forthcoming engineering design phase and site selection *** is anticipated to begin around 2027-2028,pending government approval,with an estimated duration of 8 *** commencement of experiments and data collection could potentially be initiated in the mid-2030s.

关键词： initiated exceeding precise

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Efficacy and safety of sirolimus early conversion protocol in liver transplant patients with hepatocellular carcinoma:A single-arm, multicenter, prospective study

引用

hepatobiliary & Pancreatic Diseases International 2022年第2期21卷 106-112页

作者： Ren-Yi Su Sun-Bin ling Qiao-Nan Shan Xu-Yong Wei Rui Wang Chang-Ku jia li Zhuang Tian Shen li-Min Ding Zhi-Dan Xu Lai-Bang Luo li-Bo Sun Guang-Ming li Tai-Shi Fang Nan jiang Kun Zhang zhao-Jie Su Zhi-Hai Peng Ren Lang Tao jiang Qiang he lin-Sen Ye Yang Yang yu-Ting he wen-Zhi guo liu-Gen Lan Xu-Yong Sun Dong Chen Zhi-Shui Chen Da-Wei zhou Shao-Jun Ye Qi-Fa Ye Min Tian jian-hua Shi Bo Wang jiang liu Qian Lu Wei Rao Jin-zhen Cai Tao Lv jia-Yin Yang Pu-Sen Wang lin Zhong Jing-Sheng ma Qi-Gen li Sheng-Dong Wu Chang-jiang Lu Cai-De Lu Dong-hua Zhang Xuan Wang Zi-Qiang li Mu-jian Teng Jun-Jie li wen-Tao jiang jian-hua li Quan-Bao Zhang Ning-Qi Zhu zheng-Xin Wang Kang he Qiang Xia Shao-hua Song Zhi-Ren Fu Wei Qiu guo-yue Lv Rui-Peng Song Ji-zhou Wang zheng Wang jian zhou gang Chen Ying-Peng zhao li li Ze-Min hu Qi-Jie Luo Zhong-zhou Si Bin Xie xiao-Shun he Zhi-Yong guo Shu-Sen zheng xiao Xu Department of hepatobiliary and Pancreatic Surgery The Center for Integrated Oncology and Precision MedicineAffiliated Hangzhou First People’s HospitalZhejiang University School of MedicineHangzhou 310006China NHC Key Laboratory of Combined Multi-organ Transplantation Hangzhou 310003China Department of hepatobiliary and Pancreatic Surgery Shulan(Hangzhou)HospitalZhejiang Shuren University School of MedicineHangzhou 310022China Department of hepatobiliary and Pancreatic Surgery The First Affiliated HospitalZhejiang University School of MedicineHangzhou 310003China Department of Transplantation Jiangxi Provincial People’s Hospital Affiliated to Nanchang UniversityNanchang 330006China liver Transplantation Center Beijing You’an HospitalCapital Medical UniversityBeijing 100069China Department of hepatic Surgery National Clinical Research Center for Infectious DiseaseShenzhen Third People’s HospitalThe Second Affiliated Hospital of Southern University of Science and TechnologyShenzhen 518112China Department of General Surgery Xiang’an Hospital of Xiamen UniversityXiamen 361000China Deartment of hepatobiliary and Pancreaticosplenic Surgery Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100020China Department of hepatic Surgery and liver Transplantation Center The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510630China Department of hepatobiliary and Pancreatic Surgery The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052China Department of liver Transplantation The Second Affiliated Hospital of Guangxi Medical UniversityNanning 530000China institute of Organ Transplantation Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China institute of hepatobiliary Diseases of Wuhan University Transplant Center of Wuhan UniversityHubei Key Laboratory of Medical Technology on TransplantationZhongnan Hospital of Wuhan UniversityWuhan 430071China Department of hepatobiliary Surgery The First Affiliated Hos

mammalian target of rapamycin(m TOR) inhibitor as an attractive drug target with promising antitumor effects has been widely investigated. High quality clinical trial has been conducted in liver transplant(LT) recipients in Western countries. However, the pertinent studies in Eastern world are paucity. Therefore, we designed a clinical trial to test whether sirolimus can improve recurrence-free survival(RFS) in hepatocellular carcinoma(HCC) patients beyond the Milan criteria after LT. This is an open-labeled, single-arm, prospective, multicenter, and real-world study aiming to evaluate the clinical outcomes of early switch to sirolimus-based regimens in HCC patients after LT. Patients with a histologically proven HCC and beyond the Milan criteria will be enrolled. The initial immunosuppressant regimens are center-specifc for the frst 4-6 weeks. The following regimens integrated sirolimus into the regimens as a combination therapy with reduced calcineurin inhibitors based on the condition of patients and centers. The study is planned for 4 years in total with a 2-year enrollment period and a 2-year follow-up. We predict that sirolimus conversion regimen will provide survival benefts for patients particular in the key indicator RFS as well as better quality of life. If the trial is conducted successfully, we will have a continued monitoring over a longer follow-up time to estimate indicator of overall survival. We hope that the outcome will provide better evidence for clinical decision-making and revising treatment guidelines based on Chinese population data.

关键词： Sirolimus Immunosuppressive agents hepatocellular carcinoma liver transplantation Conversion

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Data release of the LAMOST pilot survey

引用

Research in Astronomy and Astrophysics 2012年第9期12卷 1243-1246页

作者： A-li Luo Hao-tong Zhang Yong-heng zhao gang zhao Xiang-Qun Cui guo-Ping li Yao-Quan Chu jian-Rong Shi gang Wang jian-Nan Zhang Zhong-Rui Bai xiao-Yan Chen Feng-fei Wang Yan-Xin guo jian-Jun Chen Bing Du xiao Kong Ya-juan Lei Yin-Bi li Yi-Han Song yue Wu Yan-Xia Zhang Xin-lin zhou Fang Zuo Peng Du lin he wen Hou Yi-Qiao Dong jian li Guang-Wei li Shuang li Jing Song yuan Tian Meng-Xin Wang Yong-hui Hou Zhi-Ying huo Hong-Zhuan hu Ning-Sheng hu Zhong-wen hu Lei jia Fang-hua jiang Xiang jiang Zi-Bo jiang Ge Jin Ai-hua li Qi li Yin-Dun mao zheng-Hong Tang Qing-Sheng Tao liang-Ping Tu Da-Qing Wang Dan Wang jian-Ping Wang Lei Wang Shou-Guan Wang Shu-Qing Wang Ya-Nan Wang You Wang yue-fei Wang Ming-Zhi Wei Xiang-Xiang Xue xiao-zheng Xing ling-Zhe Xu Xin-Qi Xu Yan Xu De-hua Yang Shi-Hai Yang zheng-Qiu Yao Yong yu hui yuan Chao Zhai En-Peng Zhang Jing Zhang li-Ping Zhang WeiZhang Yong Zhang zhen-Chao Zhang Ming zhao Fang zhou Yong-Tian Zhu Jie Zhu Si-Cheng Zou National Astronomical Observatories Chinese Academy of Sciences Beijing 100012 China lal @ lamost o rg Nanjing institute of Astronomical Optics and Technology National Astronomical ObservatoriesChinese Academy of Sciences Nanjing 210042 China University of Science and Technologyof China Hefei 230026 China shanghai Astronomical Observatory Chinese Academy of Sciences Shanghai 200030 China institute of Architecture Design and Research Chinese Academy of Sciences Beijing 100190China

This paper describes the data release of the LAMOST pilot survey, which includes data reduction, calibration, spectral analysis, data products and data access. The accuracy of the released data and the information about the FITS headers of spectra are also introduced. The released data set includes 319 000 spectra and a catalog of these objects.

关键词： techniques: spectroscopic survey — data reduction — data release

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Timing analysis of the black hole candidate EXO 1846–031 with Insight-HXMT monitoring

引用

Research in Astronomy and Astrophysics 2021年第3期21卷 193-204页

作者： he-Xin liu yue huang Guang-Cheng xiao Qing-Cui Bu Jin-Lu Qu Shu Zhang Shuang-Nan Zhang Shu-mei jia Fang-Jun Lu Xiang ma lian Tao Wei Zhang li Chen li-Ming Song Ti-Pei li yu-Peng Xu Xue-Lei Cao Yong Chen Cong-Zhan liu Ce Cai Zhi Chang gang Chen Tian-Xiang Chen Yi-Bao Chen yu-Peng Chen Wei Cui Wei-Wei Cui Jing-Kang Deng Yong-Wei Dong yuan-yuan Du Min-Xue Fu Guan-hua Gao he Gao Min Gao Ming-yu Ge yu-Dong Gu Ju Guan Cheng-Cheng guo Da-Wei Han jia huo Lu-hua jiang Wei-Chun jiang Jing Jin Yong-Jie Jin ling-Da Kong Bing li Cheng-Kui li gang li mao-Shun li Wei li Xian li xiao-Bo li Xu-Fang li Yang-guo li zheng-Wei li xiao-hua liang Jing-yuan liao Bai-Sheng liu guo-Qing liu Hong-Wei liu xiao-Jing liu Yi-Nong liu Bo Lu Xue-Feng Lu Qi Luo Tao Luo Bin Meng Yi Nang jian-Yin Nie Ge Ou Na Sai Ren-Cheng Shang Xin-Ying Song liang Sun Ying Tan You-li Tuo Chen Wang guo-Feng Wang juan Wang ling-Jun Wang weng-Shuai Wang yu-Sa Wang Xiang-Yang wen Bai-Yang Wu Bo-Bing Wu mei Wu Shuo xiao Shao-lin Xiong he Xu jia-Wei Yang Sheng Yang Yan-Ji Yang Yi-Jung Yang Qi-Bin Yi Qian-Qing Yin yuan You Ai-mei Zhang Cheng-Mo Zhang Fan Zhang Hong-mei Zhang juan Zhang tong Zhang Wan-Chang Zhang wen-zhao Zhang Yi Zhang Yi-fei Zhang Yong-Jie Zhang yuan-Hang Zhang yue Zhang zhao Zhang Zhi Zhang Zi-liang Zhang Hai-Sheng zhao xiao-Fan zhao Shi-Jie zheng Yao-Guang zheng Deng-Ke zhou jian-Feng zhou yu-Xuan Zhu Ren-lin Zhuang yue Zhu Key Laboratory of Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Chinese Academy of SciencesBeijing 100049China institut fur Astronomie und Astrophysik Kepler Center for Astro and Particle PhysicsEberhard Karls Universität72076 TubingenGermany Department of Astronomy Beijing Normal UniversityBeijing 100088China Department of Astronomy Tsinghua UniversityBeijing 100084China Department of Physics Tsinghua UniversityBeijing 100084China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Space Astronomy and Technology National Astronomical ObservatoriesChinese Academy of SciencesBeijing 100101China College of Physics Sciences&Technology Hebei UniversityBaoding 071002Hebei ProvinceChina

We present the observational results from a detailed timing analysis of the black hole candidate EXO 1846-031 during its outburst in 2019 with the observations of Insight-HXMT,NICER and *** outburst can be classified roughly into four different ***-C quasi-periodic oscillations(QPOs)observed by NICER(about 0.1-6 Hz)and Insight-HXMT(about 0.7-8 Hz)are also reported in this ***,we study various physical quantities related to QPO *** QPO rms-frequency relationship in the energy band 1-10 keV indicates that there is a turning pointing in frequency around2 Hz,which is similar to that of GRS 1915+105.A possible hypothesis for the relationship above may be related to the inclination of the source,which may require a high inclination to explain *** relationships between QPO frequency and QPO rms,hardness,total fractional rms and count rate have also been found in other transient sources,which can indicate that the origin of type-C QPOs is non-thermal.

关键词： X-ray binaries black hole candidate QPO EXO 1846–031

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

基于个体化机器学习的原发性免疫性血小板减少症危重出血预测模型:一项全国前瞻性队列研究

引用

科学通报:英文版 2023年第18期68卷 2106-2114,M0004页

作者： Zhuo-yu An Ye-Jun Wu yu Hou heng mei Wei-Xia Nong wen-Qian li hu zhou Ru Feng jian-Ping Shen Jun Peng Hai zhou Yi liu Yong-Ping Song lin-hua Yang mei-yun Fang jian-Yong li yun-Feng Cheng Peng liu Ya-Jing Xu zhao Wang Yi Luo zhen Cai hui liu Jing-wen Wang juan li Xi Zhang Zi-Min Sun xiao-yu Zhu Xin Wang Rong Fu liang huang Shao-yuan Wang tong-hua Yang li-Ping Su liang-Ming ma Xie-Qun Chen Dai-Hong liu Hong-Xia Yao jia Feng Hong-yu Zhang Ming jiang Ze-Ping zhou wen-Sheng Wang Xu-liang Shen Yangjin Baima yue-Ying li Qian-fei Wang Qiu-Sha huang Hai-Xia Fu xiao-Lu Zhu yun he Qian jiang Hao jiang Jin Lu Xiang-yu zhao Ying-Jun Chang Tao Wu Yao-Zhu Pan lin Qiu Da Gao A-Rong Jin Wei li Su-Jun Gao Lei Zhang Ming Hou xiao-Jun huang xiao-hui Zhang on behalf of the National Cooperative ITP Working Group Peking University People’s Hospital Peking University Institute of HematologyBeijing 100044China Collaborative Innovation Center of hematology Peking UniversityBeijing 100044China Beijing Key Laboratory of hematopoietic Stem Cell Transplantation Beijing 100044China National Clinical Research Center for hematologic Disease Beijing 100044China Department of hematology Qilu HospitalCheeloo College of MedicineShandong UniversityJinan 250014China institute of hematology Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430074China Department of hematology First Affiliated HospitalSchool of MedicineShihezi UniversityShihezi 832002China Department of hematology Qinghai Provincial People’s HospitalXining 810007China henan Cancer Hospital Affiliated Cancer Hospital of Zhengzhou UniversityHenan Institute of HematologyZhengzhou 450008China Department of hematology Beijing HospitalBeijing 100044China Department of hematology Zhejiang Provincial Hospital of Traditional Chinese MedicineHangzhou 310006China Department of hematology Senior Department of Hematologythe Fifth Medical Center of PLA General HospitalBeijing 100044China Department of hematology the Second Hospital of Shanxi Medical UniversityTaiyuan 030001China Department of hematology Affiliated Zhongshan Hospital of Dalian UniversityDalian 116001China Department of hematology The First Affiliated Hospital with Nanjing Medical University(Jiangsu Province Hospital)Nanjing 210029China Department of hematology Zhongshan HospitalFudan UniversityShanghai 200032China Department of hematology Xiangya HospitalCentral South UniversityChangsha 410008China Department of hematology Beijing Friendship HospitalCapital Medical UniversityBeijing 100044China institute of hematology the First Affiliated HospitalZhejiang UniversityHangzhou 310058China Department of hematology Beijing Tongren HospitalBeijing 100005China Department of hematology The First Affiliated HospitalSun Yat-sen UniversityGuang

原发性免疫性血小板减少症(ITP)中少见但至关重要的危重出血事件,给患者的预后、生活质量和治疗决策带来严重影响。尽管有一些研究探讨了ITP中与危重出血相关的风险因素,但目前尚缺乏大样本数据、大规模多中心研究结果以及针对ITP患者... 详细信息

原发性免疫性血小板减少症(ITP)中少见但至关重要的危重出血事件,给患者的预后、生活质量和治疗决策带来严重影响。尽管有一些研究探讨了ITP中与危重出血相关的风险因素,但目前尚缺乏大样本数据、大规模多中心研究结果以及针对ITP患者致命出血事件的预测模型。本研究首次采用国际血栓与止血学会新提出的ITP致命出血标准,利用大样本数据开发了首个基于机器学习的在线应用,用于预测ITP患者的致命出血.研究中,我们使用中国各地大型多中心数据进行开发,并对全国39家医疗中心进行为期一年的外部测试,得到了较好的训练、验证和测试数据集预测能力该基于新算法的便捷网络工具能够快速识别ITP患者的出血风险,辅助临床决策,有望未来降低不良事件的发生。

关键词： Critical bleeding Severe bleeding Immune thrombocytopenia machine learning Prediction model

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

肺癌适应性治疗中国专家共识

引用

循证医学 2024年第4期24卷 193-200页

作者：吴一龙陆舜程颖周清张嘉涛潘燚汪斌超韩宝惠陈海泉周清华王绿化陈明王洁周彩存刘晓晴马智勇黄诚宋启斌莫树锦钟文昭朱正飞宋勇陈蓉蓉陈克终刘基巍杨帆胡晓桦胡毅杨懿岳东升王群赵军范江陈椿孟庆威闫小龙董晓荣朱波邢力刚李兆澄李子明褚倩陈元林根段建春田攀文范云刘安文刘慧刘哲峰杨农汪步海张同梅信涛刘思阳王志杰马锐于起涛林劼涂海燕姚煜赵明芳王慧娟张海波蔡尚立张绪超李慧杜瀛瀛吴芳严令华崔久嵬王燕邬麟周建娅汪笑男黄媚娟冯卫能周进李力中国抗癌协会肺癌专业委员会广东省临床试验协会/中国胸部肿瘤研究协作组广东省肺癌研究所南方医科大学附属广东省人民医院(广东省医学科学院)广州510080 上海交通大学医学院附属胸科医院上海200030 吉林省肿瘤医院长春130021 复旦大学附属肿瘤医院上海200032 四川大学华西医院成都610041 中国医学科学院肿瘤医院深圳医院广东深圳518116 中山大学肿瘤防治中心广州510060 中国医学科学院肿瘤医院北京100021 同济大学附属上海市肺科医院上海200433 解放军总医院第五医学中心北京100039 郑州大学附属肿瘤医院/河南省肿瘤医院郑州450003 福建省肿瘤医院福州350011 武汉大学人民医院肿瘤中心武汉430060 香港中文大学医学院中国香港东部战区总医院南京210002 北京吉因加科技有限公司北京102206 北京大学人民医院北京100044 大连医科大学附属第一医院辽宁大连116011 广西医科大学第一附属医院南宁530020 解放军总医院北京100071 成都市第三人民医院/西南交通大学医学院成都610031 天津医科大学肿瘤医院天津300060 复旦大学附属中山医院上海200032 北京大学肿瘤医院北京100142 上海交通大学附属上海市第一人民医院上海200025 福建医科大学附属协和医院福州350001 哈尔滨医科大学附属肿瘤医院哈尔滨150081 空军军医大学唐都医院西安710038 华中科技大学同济医学院附属协和医院武汉430022 陆军军医大学第二附属医院-新桥医院重庆400037 山东省肿瘤医院济南250117 华中科技大学同济医学院附属同济医院武汉430030 中国医学科学院肿瘤医院山西医院太原030013 中国科学院大学附属肿瘤医院/浙江省肿瘤医院杭州310022 南昌大学附属第二医院南昌330006 湖南省第二人民医院长沙410035 南京大学医学院附属苏北人民医院江苏扬州225001 首都医科大学附属北京胸科医院北京101149 哈尔滨医科大学附属第二医院哈尔滨150001 暨南大学附属第一医院广州510630 辽宁省肿瘤医院沈阳110042 广西医科大学附属肿瘤医院南宁530012 昆明医科大学第二附属医院昆明650101 西安交通大学第一附属医院西安710061 中国医科大学附属第一医院沈阳110001 广东省中医院广州510120 广州燃石医学检验所有限公司广州510300 安徽医科大学第一附属医院合肥230022 中南大学湘雅二医院长沙410011 上海桐树生物科技有限公司上海200444 吉林大学白求恩第一医院长春130021 湖南省肿瘤医院长沙410013 浙江大学医学院附属第一医院杭州310031 南京世和基因生物技术股份有限公司南京210032 佛山市第一人民医院广东佛山528000 四川省肿瘤医院成都610042 陆军军医大学大坪医院重庆400042 不详

由中国抗癌协会肺癌专业委员会和广东省临床试验协会/中国胸部肿瘤研究协作组主办的“第21届中国肺癌高峰论坛”于2024年3月2日在广州顺利召开。此次论坛以肺癌适应性治疗为主题,从肺癌适应性治疗定义、早中晚期临床应用以及生物标志物... 详细信息

由中国抗癌协会肺癌专业委员会和广东省临床试验协会/中国胸部肿瘤研究协作组主办的“第21届中国肺癌高峰论坛”于2024年3月2日在广州顺利召开。此次论坛以肺癌适应性治疗为主题,从肺癌适应性治疗定义、早中晚期临床应用以及生物标志物对适应性治疗的指导价值等角度展开探讨并达成了专家共识。

关键词：肺癌适应性治疗共识

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：