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Successful treatment of pyoderma gangrenosum with concomitant immunoglobulin A nephropathy: A case report and review of literature

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World Journal of Clinical Cases 2018年第13期6卷 703-706页

作者： Xiao-Li Li Zhi-gang ma Wen-Hui Huang Er-Qing Chai Yun-Fei Hao Department of Nephrology Gansu Provincial Hospital Cerebrovascular Disease Center Gansu Provincial Hospital

Pyoderma gangrenosum(PG)is an uncommon ulcerative cutaneous condition of an unknown etiology and is often associated with immune ***,PG rarely shows visceral involvement,especially in the kidney.A 20-year-old female presented with pedal edema and skin ulceration of both lower *** skin lesion began as an erythematous plaque and then became a *** also complained of abdominal distension and a decreasing urine *** data showed high proteinuria,hypoalbuminemia and *** skin and kidney were *** pathological results indicated PG and immunoglobulin A(IgA)*** patient was finally cured with prednisolone in combination with cyclosporine A(CsA).

关键词： Pyoderma gangrenosum Immunoglobulin A nephropathy Treatment

不同运动模式影响心肌梗死致心力衰竭大鼠骨骼肌重塑的机制

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中国组织工程研究 2025年第2期29卷 221-230页

作者：付常喜何瑞波马刚朱政马文超徐州工程学院体育学院江苏省徐州市221008 中国人民武装警察部队后勤学院卫生勤务系天津市300309

背景:急性心肌梗死可引起心脏重塑和心力衰竭,同时导致骨骼肌病变,影响患者生活质量。运动疗法是心力衰竭患者的重要康复手段,然而最佳运动处方尚未明确。目的:对比不同运动模式(有氧运动、抗阻运动)对急性心肌梗死诱导心力衰竭模型大... 详细信息

背景:急性心肌梗死可引起心脏重塑和心力衰竭,同时导致骨骼肌病变,影响患者生活质量。运动疗法是心力衰竭患者的重要康复手段,然而最佳运动处方尚未明确。目的:对比不同运动模式(有氧运动、抗阻运动)对急性心肌梗死诱导心力衰竭模型大鼠骨骼肌重塑的影响,探讨其可能的作用机制,为优化运动康复方案提供依据。方法:48只SD大鼠随机分为假手术组、心肌梗死组、有氧运动组和抗阻运动组。利用冠状动脉结扎术进行心力衰竭模型制作,3个月后有氧运动组和抗阻运动组进行12周相应运动模式干预,假手术组和心肌梗死组于鼠笼内安静饲养。实验后,利用递增负荷跑台运动实验和爬梯实验分别测定大鼠最高跑速和最大负重,超声心动图评估心脏结构与功能;分离出心脏,分别行苏木精-伊红染色和天狼星红染色观察心脏重塑情况;分离出腓肠肌,行ATP酶染色观察肌纤维类型和细胞横截面积改变,二氢乙锭法评估活性氧水平,酶联免疫吸附法测定丙二醛含量以及抗氧化酶活性,免疫印迹法测定泛素-蛋白酶体系统蛋白表达量,双重免疫荧光染色检测活化的卫星细胞数(Pax7^(+)/MyoD^(+))。结果与结论:①运动能力:与假手术组比较,心肌梗死组最高跑速和最大负重下降(P0.05)。③骨骼肌重塑:与假手术组比较,心肌梗死组腓肠肌质量、腓肠肌质量指数、细胞横截面积、超氧化物歧化酶活性、谷胱甘肽过氧化物酶活性、活化的卫星细胞数量下降(PmaFbx蛋白表达量上调(PmaFbx蛋白表达量降低(P<0.05);与有氧运动组比较,抗阻运动组腓肠肌质量、腓肠肌质量指数、细胞横截面积、活性氧水平、丙二醛含量、活化的卫星细胞数量升高(P<0.05),超氧化物歧化酶活性、谷胱甘肽过氧化物酶活性下调(P<0.05)。结果表明:有氧运动和抗阻运动均可提升心力衰竭大鼠的运动能力,其机制与减轻氧化应激、抑制泛素-蛋白酶体系统活性以及激活卫星细胞进而改善骨骼肌重塑有关。有氧运动对于改善骨骼肌氧化应激作用更佳,而抗阻运动促进骨骼肌再生方面效果更为显著。

关键词：心肌梗死心力衰竭运动心脏骨骼肌重塑

Hypernuclei as a laboratory to test hyperon–nucleon interactions

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Nuclear Science and Techniques 2023年第6期34卷 5-8页

作者： Yu-gang ma Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai200433China Shanghai Research Center for Theoretical Nuclear Physics NSFC and Fudan UniversityShanghai200438China

Directed flow(v_(1))of the hypernuclei ^(3)_(Λ)H and ^(4)_(Λ)H have been observed in mid-central Au+Au collisions at√^(s)NN=3 GeV at *** measurement opens up a new possibility for studying hyperon–nucleon(Y–N)interaction under finite *** addition,multi-strangeness hypernuclei provide a venue to probe hyperon–nucleon–nucleon(Y–N–N)and even hyperon–hyperon–nucleon(Y–Y–N)*** are important for making connection between nuclear collisions and the equation of state which governs the inner structure of compact stars.

关键词： nucleon addition equation

Stochastic Equations for Two-type Continuous-state Branching Processes with Immigration

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Acta mathematica Sinica,English Series 2013年第2期29卷 287-294页

作者： Ru gang ma School of mathematical Sciences Beijing Normal University

A two-dimensional stochastic integral equation system with jumps is studied. We first prove its unique weak solution is a two-type continuous-state branching process with immigration. Then the comparison property of the solution is established. These results imply the existence and uniqueness of the strong solution of the stochastic equation system.

关键词： Continuous-state branching process immigration stochastic integral equation comparison property strong solution

New type of double‑slit interference experiment at Fermi scale

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Nuclear Science and Techniques 2023年第1期34卷 175-177页

作者： Yu‑gang ma Key Laboratory of Nuclear Physics and Ion‑beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China Shanghai Research Center for Theoretical Nuclear Physics NSFC and Fudan UniversityShanghai 200438China

A new approach that using polarized photon–gluon collisions reported by STAR Collaboration is used to do tomography of the ultrarelativistic *** collision can be treated as a double-slit experiment at Fermi scale and... 详细信息

关键词： Fermi double radius

Nuclear Zpif-Type Plots

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Chinese Physics Letters 2000年第5期17卷 340-342页

作者： ma Yu-gang Shanghai Institute of Nuclear Research Chinese Academy of SciencesShanghai 201800 CCAST(World Laboratory) P.O.Box 8730Beijing 100080

Isospin dependent classical molecular dynamics model is used to investigate the nuclear disassembly of^(129)***-type plot in the field of linguistics is tested for the rank-classified cluster arrangement from this *** is found that the average cluster charge(or mass)of rank n in the charge(or mass)list is exactlyinverse to its rank,*** exists Zpif's law at the point of the liquid gas phase *** novel criterioncan be used to diagnose the nuclear liquid gas phase transition experimentally and theoretically.

关键词： transition cluster rank

α-clustering effect on flows of direct photons in heavy-ion collisions

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Nuclear Science and Techniques 2021年第6期32卷 122-132页

作者： Chen-Zhong Shi Yu-gang ma Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China Key Laboratory of Nuclear Physics and Ion-beam Application(MOE) Institute of Modern PhysicsFudan UniversityShanghai 200433China University of the Chinese Academy of Sciences Beijing 100080China

In this study,we reconstruct theγ-photon energy spectrum,which is in good agreement with the experimental data of ^(86)Kr+^(12)C at E/A=44 Me V within the framework of the modified EQMD *** directed and elliptic flows of free protons and direct photons were investigated by considering theα-clustering structure of ^(12)*** with free protons,direct photon flows provide clearer information about the early stage of a nuclear *** difference in the collective flows between different configurations of ^(12)C is observed in this *** indicates that the collective flows of direct photons are sensitive to the initial ***,theγbremsstrahlung process might be taken as an alternative probe to investigate theα-clustering structure in a light nucleus from heavy-ion collisions within the Fermienergy region.

关键词： Nuclear reaction Direct photon Collective flow α-clustering configuration

Measurements of momentum correlation and interaction parameters between antiprotons

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Nuclear Science and Techniques 2016年第6期27卷 67-73页

作者： Zheng-Qiao Zhang Yu-gang ma Shanghai Institute of Applied Physics Chinese Academy ofSciencesShanghai 201800China University of Chinese Academy of Sciences Beijing 100049China

The two-particle momentum correlation is influenced by the nuclear force between two particles,which has been intensively studied for nucleons and nuclei,but not much for antinucleons or *** this proceeding,we present our STAR measurements on momentum correlation function of antiproton-antiproton and proton-proton in Au+Au collisions at S_(NN)^(1/2)= 200 GeV at the Relativistic Heavy Ion *** nuclear force between two antiprotons is demonstrated,and the strong interaction parameters(the scattering length and the effective range) are *** measurement serves as an additional verification of CPT *** present information on the strong force in the antiproton-antiproton system provides a fundamental ingredient towards understanding the structure of more sophisticated antinuclei.

关键词：动量相关作用相互作用参数反质子测量重离子对撞机散射长度核力量金+金

Recent progress in the study of Hedgehog signaling

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Journal of Genetics and Genomics 2008年第3期35卷 129-137页

作者： gang ma Yue Xiao Lin He Bio-X Center Shanghai Jiao Tong University Shanghai 200030 China Institute for Nutritional Sciences Shanghai Institutes for Biological Sciences （SIBS） Chinese Academy of Sciences Shanghai 200031 China Institutes of Biomedical Sciences Fudan University Shanghai 200032 China

The Hedgehog （Hh） family of secreted signaling proteins plays a critical role in regulating the development of several tissues and organ systems. The ability of Hh proteins to exert their biological effects is regulated by a series of post-translational processes. These processes include an intramolecular cleavage, covalent addition of cholesterol and/or palmitate, and conversion into a multimeric freely diffusible form. The processing of Hh proteins affects their trafficking, potency, and ability to signal over several cell diameters. Here we review the current understanding of the Hh signaling mechanisms that govern the establishment of the Hh gradient and the transduction of the Hh signal in the light of recent data.

关键词： Hedgehog processing signal transduction