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基于改进邻域空间的高维混合数据特征选择算法

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控制与决策 2024年第3期39卷 929-938页

作者：张腾飞张宇迪马福民南京邮电大学自动化学院人工智能学院南京210023 南京财经大学信息工程学院南京210023

作为数据挖掘领域中一项重要的数据预处理技术,特征选择算法能够有效应对高维数据带来的“维数灾难”问题.然而,如何对高维的混合数据进行特征选取仍然是当前研究的重点和难点之一.基于邻域关系的邻域粗糙集模型因其能够处理名词型属性... 详细信息

作为数据挖掘领域中一项重要的数据预处理技术,特征选择算法能够有效应对高维数据带来的“维数灾难”问题.然而,如何对高维的混合数据进行特征选取仍然是当前研究的重点和难点之一.基于邻域关系的邻域粗糙集模型因其能够处理名词型属性与数值型属性并存的混合数据,已成功应用于混合数据的特征选择.但是,现有邻域粗糙集对混合数据邻域关系的度量,仍然是基于等价关系的名词型数据划分与基于相似关系的数值型数据划分的简单融合,在利用模型划分的邻域空间和预定义的评价函数对高维混合数据进行特征选取时,适应性较差.为此,在邻域粗糙集模型的基础上,提出一种改进的邻域空间构造方法,并设计相应的邻域空间度量公式作为判别指标,自适应地调节邻域空间下邻域粒的大小;为了准确地表征高维混合数据邻域空间的判别能力,设计一种考虑边界数据和邻域空间大小的评价函数;在此基础上,提出一种启发式的高维混合数据特征选择算法.通过UCI标准数据集验证所提出算法的有效性.

关键词：特征选择邻域空间高维混合数据邻域粗糙集评价函数

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3个品牌毛豆腐风味成分对比研究

中国调味品 2024年第3期49卷 150-156页

作者：王凤杰吕伟黄一承段翠翠马福敏李晓磊李丹长春大学农产品加工吉林省普通高等学校重点实验室长春130022

毛豆腐的风味决定了消费者的喜好程度。以3个品牌的毛豆腐为研究对象,对比分析了它们的非挥发性成分和挥发性成分。结果表明,采用高效液相色谱法共检测出7种有机酸,其中琥珀酸含量最高,其次是乳酸,含量范围分别为1.77~7.47 mg/mL,2.46~3... 详细信息

毛豆腐的风味决定了消费者的喜好程度。以3个品牌的毛豆腐为研究对象,对比分析了它们的非挥发性成分和挥发性成分。结果表明,采用高效液相色谱法共检测出7种有机酸,其中琥珀酸含量最高,其次是乳酸,含量范围分别为1.77~7.47 mg/mL,2.46~3.20 mg/mL;共检测出21种游离氨基酸,其中含量最高的氨基酸分别为谷氨酰胺、苏氨酸和精氨酸,在品牌A、B、C中含量分别为2566.55,1282.69,1465.81 mg/g;采用气相色谱-质谱法共检测出61种挥发性风味物质,品牌A、B、C中分别检测出41,38,33种;电子鼻分析显示,毛豆腐在气味上的差异主要体现在硫化物、芳香成分和氮氧化合物方面,能整体显著区分挥发性成分。OAV≥1的挥发性风味物质共15种。正交偏最小二乘判别分析表明,9种VIP>1的挥发性成分为主要差异性成分。结论:3个品牌毛豆腐风味物质之间存在显著性差异。

关键词：毛豆腐有机酸游离氨基酸非挥发性风味挥发性风味

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Synthesis and characterization on a novel series of protic pyrrolidinium surfactants

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Chinese Chemical Letters 2010年第4期21卷 385-387页

作者： ma, fu min Chen, Xiao Wang, Xu Dong Zhao, Yu Rong Li, Qiu Hong Yue, Xiu Lv, Chao Shandong Univ Minist Educ Key Lab Colloid & Interface Chem Jinan 250100 Peoples R China

A novel series of protic tertiary pyrrolidinium surfactants were prepared and characterized by different *** compounds show good conductivity and efficient ability to reduce surface *** analysis proves their high thermal stability at decomposition temperatures over 250℃.Their lyotropic and thermotropic liquid crystalline properties are also discussed.

关键词： Protic pyrrolidinium surfactants Liquid crystal Conductivity Surface tension

Paeoniflorin,the main Monomer Component of Paeonia lactiflora,Exhibits Anti-inflammatory Properties in Osteoarthritis Synovial Inflammation

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Chinese Journal of Integrative Medicine 2024年第5期30卷 433-442页

作者： CHEN Pu ZHOU Jun RUAN An-min ma Yu-feng WANG Qing-fu Department of Orthopaedic Surgery Beijing University of Chinese Medicine Third Affiliated HospitalBeijing 100029China Department of Orthopaedic Surgery Guangdong Provincial Hospital of Chinese MedicineGuangzhou 510120China Department of Orthopaedic Surgery Beijing Longfu HospitalBeijing 100010China

Objective:To explore the mechanism of paeoniflorin(PF)on osteoarthritis(OA)synovial inflammation from network pharmacology to experimental ***:Targets of OA were constructed by detecting the database of network database platforms(Therapeutic Target database,Drug Bank and Gene Cards),and the targets of PF were constructed by Pub Chem and Herbal Ingredients'Targets *** Ontology(GO)and Kyoto Encyclopedia of Genes and Genomes(KEGG)analysis of these co-targeted genes were conducted via Database for Annotation,Visualization,and Integrated Discovery(DAVID)database,and protein-protein interaction(PPI)networks were conducted via the search tool for the retrieval of interacting genes(STRING)*** counting kit-8(CCK-8)assay was performed to assess the potential toxicity of PF on human OA fibroblast-like synoviocytes(FLS),quantitative real-time polymerase chain reaction(q PCR),enzyme-linked immunosorbent assay(ELISA)and Western blot were used to verify the potential mechanism of PF in synovial ***:Twenty-six co-targeted genes were *** enrichment results showed that these co-targeted genes were most likely localized in the cytoplasm,and the biological processes mainly involved'cellular response to hypoxia''lipopolysaccharide(LPS)-mediated signaling pathway'and'positive regulation of gene expression'.KEGG pathway analysis indicated that these co-targeted genes may function through pathways associated with'hypoxia-inducible factor-1(HIF-1)signaling pathway'and'tumornecrosis factor(TNF)signaling pathway'.The PPI network showed that the top 3 hub genes were TP53,TNF,and *** docking results showed that PF was well docking with ***-8 showed no potential toxicity of 10,20 and 50μmol/L PF on human OA *** PF significantly decreased the expression levels of interleukin-1β,interleukin-6,TNF-αmatrix metalloproteinase 13(MMP13),and a disintegrin and metalloproteinase with thrombospondin motifs 5(ADAMTS5)and TNF

关键词： paeoniflorin osteoarthritis synovial inflammation tumor necrosis factor-α network pharmacology Paeonia lactiflora

Optimizing surgical approaches for lacrimal gland adenoid cystic carcinoma to minimize cross-organ invasion

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International Journal of Ophthalmology(English edition) 2024年第10期17卷 1949-1952页

作者： ming-Shen ma Ting-Ting Ren fu-Xiao Luan Jing Li Nan Wang Yong Tao Jian-min ma Department of Ophthalmology Beijing Chaoyang HospitalCapital Medical UniversityBeijing 100027China Department of Ocular Oncology Beijing Tongren HospitalCapital Medical UniversityBeijing 100005China Gies College of Business University of Illinois at Urbana-ChampaignChampaignIL 61820United States

AIM:To evaluate the outcomes of eye-sparing surgery for lacrimal gland adenoid cystic carcinoma and the impact on tumor recurrence and orbital ***:The study enrolled four patients with recurrent lacrimal gland adenoid cystic *** outcome focused on the relevance of the integrity of the lateral orbital wall to the occurrence of extraorbital metastasis in the local recurrence of lacrimal gland adenoid cystic ***:Three patients underwent eye-sparing surgery via lateral orbitotomy without postoperative radiotherapy,and one patient who underwent eye-sparing surgery via sub-brow *** four patients all demonstrated a recurrence involving the invasion of extraorbital tissues as metastatic form through surgical bone ***:Preserving intact orbital bone tissue is crucial for mitigating direct cross-organ metastasis of lacrimal gland adenoid cystic *** findings suggest avoiding the lateral orbitotomy approach with no or limited orbital bone wall invasion.

关键词： lacrimal gland adenoid cystic carcinoma recurrence eye-sparing surgery

面向企业能源消耗过程的模糊Petri网模型研究

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计算机集成制造系统 2007年第9期13卷 1679-1685页

作者：马福民王坚同济大学CIMS研究中心上海200092

针对企业能源消耗系统模型的需求性,在分析企业能源消耗过程的特点和模糊Petri网基本原理的基础上,从实用、可行的角度探索基于模糊Petri网的企业能耗过程模型,详细阐述了面向企业能源消耗过程的模糊Petri网模型的定义和运行规则,并依... 详细信息

针对企业能源消耗系统模型的需求性,在分析企业能源消耗过程的特点和模糊Petri网基本原理的基础上,从实用、可行的角度探索基于模糊Petri网的企业能耗过程模型,详细阐述了面向企业能源消耗过程的模糊Petri网模型的定义和运行规则,并依据特定的建模原则,进行举例说明。模型的建立独立于特定的能源类型和用能设备,全面反映企业能耗过程及其影响因素,为进一步仿真分析企业能耗状况提供了依据。

关键词：能源消耗模糊Petri网过程建模

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支持企业能效评估的能源消耗过程仿真方法

计算机集成制造系统 2008年第12期14卷 2361-2368页

作者：马福民王坚同济大学CIMS研究中心上海200092

为定量和定性分析企业能源消耗情况,结合企业能源消耗过程多装置、多过程、多工序的并行、串行、返流等特性,在研究面向企业能源消耗过程的模糊扩展Petri网的基础上,深入分析了模型的有效冲突及其解决策略,提出了基于该模型的企业能源... 详细信息

为定量和定性分析企业能源消耗情况,结合企业能源消耗过程多装置、多过程、多工序的并行、串行、返流等特性,在研究面向企业能源消耗过程的模糊扩展Petri网的基础上,深入分析了模型的有效冲突及其解决策略,提出了基于该模型的企业能源消耗过程仿真方法,并详细地给出了仿真模型和仿真算法的具体实现。实例仿真表明,该方法可以有效地模拟企业生产过程中能源使用与消耗的动态行为,为企业提供直接能耗、间接能耗等相关数据,是一种行之有效的企业能效评估方法。

关键词：能效评估能源消耗模糊扩展Petri网模型过程仿真

An unexpected stereochemical effect of thio-substituted Asp in native chemical ligation

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Chinese Chemical Letters 2024年第8期35卷 278-281页

作者： min fu Pan He Sen Zhou Wenqiang Liu Bo ma Shiying Shang Yaohao Li Ruihan Wang Zhongping Tan State Key Laboratory of Bioactive Substance and function of Natural Medicines Institute of Materia MedicaChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijing 100050China Center of Pharmaceutical Technology School of Pharmaceutical SciencesTsinghua UniversityBeijing 100084China Chemical Engineering College Hebei Normal University of Science and TechnologyQinhuangdao 066600China

This study presents an unexpected finding that the cis isomer of β-thio-Asp exhibits higher ligation ac-tivity than the trans *** discovery sheds light on the intricate nature of native chemical ligation and highligh... 详细信息

关键词： Native chemical ligation Stereochemistry Ligation activity β-Thio-Asp Intramolecular hydrogen bond

Digital twin driven and intelligence enabled content delivery in end-edge-cloud collaborative 5G networks

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Digital Communications and Networks 2024年第2期10卷 328-336页

作者： Bo Yi Jianhui Lv Xingwei Wang Lianbo ma min Huang College of Computer Science and Engineering Northeastern UniversityShenyang110169China Pengcheng Lab. Shenzhen518055China College of Software Northeastern UniversityShenyang110819China College of Information Science and Engineering Northeastern UniversityShenyang110819China

The rapid development of 5G/6G and AI enables an environment of Internet of Everything(IoE)which can support millions of connected mobile devices and applications to operate smoothly at high speed and low ***,these massive devices will lead to explosive traffic growth,which in turn cause great burden for the data transmission and content *** challenge can be eased by sinking some critical content from cloud to *** this case,how to determine the critical content,where to sink and how to access the content correctly and efficiently become new *** work focuses on establishing a highly efficient content delivery framework in the IoE *** particular,the IoE environment is re-constructed as an end-edge-cloud collaborative system,in which the concept of digital twin is applied to promote the *** on the digital asset obtained by digital twin from end users,a content popularity prediction scheme is firstly proposed to decide the critical content by using the Temporal Pattern Attention(TPA)enabled Long Short-Term Memory(LSTM)***,the prediction results are input for the proposed caching scheme to decide where to sink the critical content by using the Reinforce Learning(RL)***,a collaborative routing scheme is proposed to determine the way to access the content with the objective of minimizing *** experimental results indicate that the proposed schemes outperform the state-of-the-art benchmarks in terms of the caching hit rate,the average throughput,the successful content delivery rate and the average routing overhead.

关键词： Digital twin IoE Content delivery Caching Routing