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Changes in smoking behavior and adherence to preventive guidelines among smokers after a heart attack

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Journal of Geriatric Cardiology 2013年第2期10卷 146-150页

作者： Yoon-Jung Choi Jong-Seon Park Ung kim Sang-Hee Lee Jang-Won Son Dong-Gu Shin Young-Jo kim Myung-Ho Jeong Young-Keun Ahn myeong-Chan Cho Jang-Whan Bae Chong-jin kim jin-Man Cho Kyoo-Rok Han Jun-Hee Lee Divison of Cardiology Department of Internal Medicine Yeungnam University Hospital 170 Hyeonchung-ro Nam-gu Daegu 705-717 South Korea Division of Cardiology Department of Internal Medicine Chonnam National University Hospital 42 Jebong-ro Dong-gu Kwangju 501-757 South Korea Divison of Cardiology Department of Internal Medicine Chungbuk National University Hospital 410 Sungbong-ro Heungdeok-gu Cheongju Chungcheongbuk-do 361-711 South Korea Division of Cardiology Department of Internal Medicine Kyunghee University Hospital 892 Dongnam-ro Gandong-gu Seoul 134-727 South Korea Division of Cardiology Department of Internal Medicine Hanrim University Hospital 94-195 Yeongdeungpo-dong Yeongdeungpo-gu Seoul 150-030 South Korea

Objective Risk factor modification is key to preventing subsequent cardiac events after a heart attack. This study was designed to investigate the disparity between preventive guidelines and clinical practice among smoking patients. Methods The study was carried out in smokers admitted with myocardial infarction (MI). Atotal of 275 patients who had been regularly followed for over one year after MI were randomly selected and enrolled in this *** investigated changes in smoking behavior and the adherence rate to ACC/AHA Guidelines for secondary prevention in patients with coronary artery disease at the time of, and one year after, the index event. Results The study population consisted of 275 patients (97.1% males) with a mean age of 57.0 ±11.2 years. Achievement of target goals at one year was as follows: smoking cessation, 52.3%; blood pressure, 83.9%; HbA1c, 32.7%; lipid profile, 65.5%; and body mass index (BMI), 50.6%. Over one year, 80% of the patients attempted to quit smoking; 27% of them re-started smoking within one month after discharge while 65% succeeded in cessation of smoking. At one year, only 52% of the patients overall had stopped smoking. From the multivariate logistic analysis including smoking patterns and clinical characteristics, the severity of coronary artery disease was the only independent predictor for smoking cessation (Relative risk (RR): 1.230; P = 0.022). Conclusions Only a small percentage of MI patients adhere to guidelines for secondary prevention and a sizable proportion fail to stop smoking. These findings underscore the need for an effective patient education system.

关键词： Coronary artery disease Myocardial infarction Prevention Smoking

Acupuncture for Bell's Palsy:A Systematic Review and Meta-analysis

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Chinese Journal of Integrative Medicine 2012年第1期18卷 48-55页

作者： Jong-In kim myeong Soo Lee Tae-Young Choi Hyangsook Lee Hyo-Jung Kwon Department of Acupuncture and Moxibustion College of Korean MedicineKyung Hee UniversitySeoulRepublic of Korea Brain Disease Research Center Korea Institute of Oriental Medicine DaejeonRepublic of Korea Acupuncture and Meridian Science Research Center College of Korean MedicineKyung Hee UniversitySeoulRepublic of Korea

Objective： To assess the clinical evidence for and against acupuncture as a treatment for Bell＇s palsy. Methods： We conducted a literature search of 15 databases from their inception to December 2010 without language restrictions. We included all randomized clinical trials （RCTs） regardless of their controls. Methodological quality was evaluated using the Cochrane risk of bias assessment tool. Results： Of the 3 474 articles, only eight RCTs met our inclusion criteria. Four RCTs tested the effects of acupuncture against drug therapy on disease response rate. The meta-analysis of these data showed significant improvements in the acupuncture group [n=463, risk ratio （RR）=1.07, 95% CI： 1.02 to 1.13; P=0.006, I^2=0%]. Six RCTs tested the effects of acupuncture plus drug therapy versus drug therapy alone. The meta-analysis of this set of RCTs also showed the favorable effects of acupuncture on disease response rate （n=512, RR=1.11, 95% CI： 1.05 to 1.17; P=0.001, I^2=13%）. Conclusions： The evidence supporting the effectiveness of acupuncture for treating Bell＇s palsy is limited. The number and quality of trials are too low to form firm conclusions. Further rigorous RCTs are warranted but need to overcome the many limitations of the current evidence.

关键词： acupuncture Bell's palsy systematic review

Moxibustion for Managing Type 2 Diabetes Mellitus:A Systematic Review

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Chinese Journal of Integrative Medicine 2011年第8期17卷 575-579页

作者： Tae-Hun kim Tae-Yong Choi Byung-Cheul Shin myeong Soo Lee Department of Cardiovascular and Neurologic Diseases College of Oriental MedicineGraduate SchoolKyung Hee University Acupuncture Moxibustion and Meridian Research CenterKorea Institute of Oriental Medicine Brain Disease Research Centre Korea Institute of Oriental Medicine Division of Clinical Medicine School of Korean MedicinePusan National University

Objective：Moxibustion is currently used for treating diabetes mellitus（DM） as a non-drug intervention in East Asian *** systematic review aims to evaluate the effectiveness of moxibustion for managing the symptoms of type 2 DM ***：We searched MEDLINE,AMED,EMBASE,CINAHL, The Cochrane Library,six Korean databases,and four Chinese *** of bias was used for evaluating the quality of the included ***：A total of 5 studies met the inclusion criteria for this *** of the included studies had high risks of *** randomized clinical trial（RCT） compared the effectiveness of one-time moxibustion use with oral administration of glibenclimide and showed the significant effects of moxibustion on glycemic *** RCT tested the effectiveness of moxibustion plus conventional treatment,and the moxibustion group reported significant improvement in fasting and postprandial blood glucose levels compared with the conventional treatment *** RCTs compared the effectiveness of moxibustion versus acupuncture or moxibustion plus acupuncture,and the combined treatment showed the most favorable effects on the control of blood glucose,urine glucose,and glycocylated hemoglobin A_（1C）（HbA_（1C））.One uncontrolled observational study showed favorable effects of moxibustion on the response ***：It is difficult to conclude that moxibustion is an effective intervention for the control of type 2 DM due to the scarcity of trials and the low methodological quality of included *** rigorous RCTs may be necessary to evaluate the effectiveness of moxibustion for type 2 DM.

关键词： moxibustion diabetes mellitus type 2 diabetes mellitus blood glucose systematic review

Attractor landscape analysis of the cardiac signaling network reveals mechanism-based therapeutic strategies for heart failure

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Journal of Molecular Cell Biology 2018年第3期10卷 180-194页

作者： Daebeom Park Ho-Sung Lee Jun Hyuk Kang Seon-myeong kim Jeong-Ryeol Gong Kwang-Hyun Cho Laboratory for Systems Biology and Bio-inspired Engineering Department of Bio and Brain Engineering Korea Advanced Institute of Science and Technology (KAIST) Daejeon 34141 Republic of Korea Graduate School of Medical Science and Engineering KAIST Daejeon 34141 Republic of Korea

Apoptosis and hypertrophy of cardiomyocytes are the primary causes of heart failure （HF）, a global leading cause of death, and are regulated through the complicated intracellular signaling network, limiting the development of effective treatments due to its complexity. To identify effective therapeutic strategies for HF at a system level, we develop a large-scale comprehensive mathematical model of the cardiac signaling network by integrating all available experimental evidence. Attractor landscape analysis of the network model identifies distinct sets of control nodes that effectively suppress apoptosis and hypertrophy of cardiomyocytes under ischemic or pressure overload-induced HF, the two major types of HF. Intriguingly, our system-level analysis suggests that intervention of these control nodes may increase the efficacy of clinical drugs for HF and, of most importance, different combinations of control nodes are suggested as potentially effective candidate drug targets depending on the types of HF. Our study provides a systematic way of developing mechanism-based therapeutic strategies for HF.

关键词： heart failure mathematical modeling cardiac signaling network systems analysis disease mechanism mechanism-based therapeutic strategy systems biology

Source Rate Bound for Feedback-based Video Transmission under the End-to-End Delay Constraint

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Source Rate Bound for Feedback-based Video Transmission unde...

Development of a simple model for batch and boundary information updation for a similar ship's block model

亚太地区通信会议暨光电子通信会议

作者： myeong-jin Lee Jae-Kyoon kim Visual Communications Lab Dept.of Electrical Engineering KAIST373-1Kusong-dong Yusong-gu Taejon305-701 Korea Visual Communications Lab Dept.of Electrical Engineering KAIST373-1Kusong-dong Yusong-gu Taejon305-701 Korea

In this paper,we consider a feedback-based video transmissionsystem over ATM ABR service under the constraints of fixed end-to-end *** lower bound of future available rates is obtainedby the states of leaky-buckets for high-priority connections and theoccupancy of switch *** on this bound,an upper boundof feedback rates are derived,that guarantees the end-to-end *** results are given for some test sequencesand operation parameters.

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Science China(Information Sciences) 2012年第5期55卷 1019-1031页

作者： LEE Hyeon-deok SON myeong-jo OH Min-jae LEE Hyung-woo kim Tae-wan Daewoo Shipbuilding & Marine Engineering Co. LTD.Geoje 656-714South Korea Department of Naval Architecture and Ocean Engineering Seoul National UniversitySeoul 151-744South Korea Research Institute of Marine Systems Engineering Seoul National UniversitySeoul 151-744South Korea

In early 2000,large domestic shipyards introduced shipbuilding 3D computer-aided design (CAD) to the hull production design process to define manufacturing and assembly *** production design process accounts for most of the man-hours (M/H) of the entire design process and is closely connected to yard production because designs must take into account the production schedule of the shipyard,the current state of the dock needed to mount the ship’s block,and supply ***,many shipyards are investigating the complete automation of the production design process to reduce the M/H for ***,these problems are still currently unresolved,and a clear direction is needed for research on the automatic design base of manufacturing rules,batches reflecting changed building specifications,batch updates of boundary information for hull members,and management of the hull model change history to automate the production design *** this study,a process was developed to aid production design engineers in designing a new ship’s hull block model from that of a similar ship previously built,based on AVEVA *** automation system that uses the similar ship’s hull block model is proposed to reduce M/H and human errors by the production design ***,scheme files holding important information were constructed in a database to automatically update hull block model ***,for batch updates,the database’s table,including building specifications and the referential integrity of a relational database were *** particular,this study focused on reflecting the frequent modification of building specifications and regeneration of boundary information of the adjacent panel due to changes in a specific ***,the rollback function is proposed in which the database (DB) is used to return to the previously designed panels.

关键词： ship design production design model reuse model history management referential integrity scheme file

A Web-based machining process monitoring system for E-manufacturing implementation

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2006年第9期7卷 1467-1473页

作者： SHIN Bong-cheol kim Gun-hee CHOI jin-hwa JEON Byung-cheol LEE Honghee CHO myeong-woo HAN jin-yong PARK Dong-sam Division of Mechanical Engineering Inha University Incheon 402-751 Korea Department of Mechanical Engineering University of Incheon Incheon 402-749 Korea

Recently, with the rapid growth of information technology, many studies have been performed to implement Web-based manufacturing system. Such technologies are expected to meet the need of many manufacturing industries who want to adopt E-manufacturing system for the construction of globalization, agility, and digitalization to cope with the rapid changing market requirements. In this research, a real-time Web-based machine tool and machining process monitoring system is developed as the first step for implementing E-manufacturing system. In this system, the current variations of the main spindle and feeding motors are measured using hall sensors. And the relationship between the cutting force and the spindle motor RMS (Root Mean Square) current at various spindle rotational speeds is obtained. Thermocouples are used to measure temperature variations of important heat sources of a machine tool. Also, a rule-based expert system is applied in order to decide the machining process and machine tool are in normal conditions. Finally, the effectiveness of the developed system is verified through a series of experiments.

关键词： E-manufacturing Web-based system Internet Machining process monitoring Expert system

An evaluation of the influence of impurity concentration and composition in concrete on activation and radiation dose in the reactor facility

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辐射防护 2020年第6期40卷 486-490页

作者： Jae Hyun kim myeong Hyeon WOO Chang Ho SHIN Jong Kyung kim Department of Nuclear Engineering Hanyang University222Wangsimni-roSeongdongSeoulKorea

The content analysis of radioactive waste and radiation dose evaluation is considered as one of the important factors in the reactor facility *** kind of buildings consists of the concrete for the most part and uses it as the structure and shield of the ***,the concrete has impurities such as cobalt,europium,nickel,and cesium with specific content depending on the production method or manufacturing *** radioactive nuclides generated from the fundamental components of concrete are considered that it is less contributed to the radiation dose because they are beta decay nuclides in ***,impurities of irradiated concrete in the reactor facilities,are considered occasionally an important evaluation factor for induced *** this study,the influence on the activation of impurities in concrete was evaluated from the radiation dose and induced activity *** calculation was evaluated at the bio-shield which is one of the areas with the highest neutron irradiation among the concrete structure in the reactor *** results show that radioactive nuclides with gamma decay were produced in these ***,the radiation dose of concrete with impurities was higher than concrete without *** increased radiation dose was quantified through the content of impurities.

关键词： radiation dose concrete impurity activation analysis

Protective effects of electroacupuncture on acetylsalicylic acid-induced acute gastritis in rats

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World Journal of Gastroenterology 2009年第8期15卷 973-977页

作者： Hye Suk Hwang Kyung-Ju Han Yeon Hee Ryu Eun jin Yang Yoo Sung kim Sang Yong Jeong Young-Seop Lee myeong Soo Lee Sung Tae Koo Sun-Mi Choi Department of Medica Research Korea Institute of Oriental Medicine Daejeon 305-811 South Korea Division of Meridian and Structural Medicine School of Oriental Medicine Pusan National University Pusan 609-735 South Korea

AIM: To investigate the protective effects of electroacupuncture (EA) pretreatment on acetylsalicylic acid (ASA)-induced ulceration in rats. METHODS: We randomly divided 72 rats into three groups including control (administered with distilled water), ASA group (administered 100 mg/kg ASA) and EA group (administered EA + 100 mg/kg ASA). Each rat was fasted for 18 to 24 h before experimentation, and lesion scores, gastric acidity, cyclooxygenase (COX)-1 and -2 mRNA levels, and total nitric oxide (NO) concentration were measured. RESULTS: The lesion scores of the EA group were significantly lower than those of the ASA group. Gastric acidity of the ASA and EA groups was reduced compared to the control group. COX-1 and -2 mRNA levels were significantly increased in the EA group as compared to the control and ASA groups, and NO levels were also significantly increased in the EA group as compared to the ASA group. CONCLUSION: These results suggest that EA-mediated protection against ASA-induced ulceration in rats may occur via gastric defense components.

关键词： Electroacupuncture Acute gastritis Cyclooxygenase Nitric Oxide