检索结果-南通市图书馆

Design and evaluation of Swift routing for payment channel network

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Blockchain(Research and Applications) 2024年第2期5卷 62-72页

作者： Neeraj Sharma Kalpesh Kapoor v.Anirudh Department of Computer Science and Engineering Indian Institute of Technology GuwahatiGuwahati 781039AssamIndia Department of mathematics Indian Institute of Technology GuwahatiGuwahati 781039AssamIndia

Payment Channel Networks(PCNs)are a promising alternative to improve the scalability of a blockchain network.A PCN employs off-chain micropayment channels that do not need a global block confirmation procedure,thereby sacrificing the ability to confirm transactions *** uses a routing algorithm to identify a path between two users who do not have a direct channel between them to settle a *** performance of most of the existing centralized path-finding algorithms does not scale with network *** rapid growth of Bitcoin PCN necessitates considering distributed ***,the existing decentralized algorithms suffer from resource *** present a decentralized routing algorithm,Swift,focusing on fee *** concept of a secret path is used to reduce the path length between a sender and a receiver to optimize the ***,we reduce a network structure into combinations of cycles to theoretically study fee optimization with changes in cloud *** secret path also helps in edge load sharing,which results in an improvement of *** routing achieves up to 21%and 63%in fee and throughput optimization,*** results from the simulations follow the trends identified in the theoretical analysis.

关键词： Blockchain Payment channel networks Bitcoin Lightning network Routing protocols Layer 2 protocols

How Common can the Origin of Clusters Cha Ⅰ, Cha Ⅱ, ∈Cha and η Cha be?

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第5期24卷 28-34页

作者： v.v.Bobylev A.T.Bajkova Pulkovo Astronomical Observatory St.-Petersburg 196140Russia

The trajectories of the groupings η Cha,∈Cha and Cha I,Cha II,constructed backward in time,have been *** concluded that the hypothesis about the joint formation of all four of these clusters from one molecular cloud cannot be completely ***,10–15 myr ago,all these four clusters were located at approximately the same height above the plane of the ***,the gas-dust clouds from which all these four clusters were formed were located on one broad *** is possible that the appearance of the Cha I,Cha II,∈Cha and η Cha clusters may be associated with the impact on such a front of shock waves formed after supernova explosions in the Scorpius–Centaurus *** estimates of the kinematic ages of the clusters Cha I and Cha II are obtained as 0.12±0.19 and 0.05±0.15,*** is shown that the minimum size of the Cha I-north and Cha I-south clusters corresponded to the time of 0.55±0.24 myr and 0.04±0.18 myr ago,respectively,and approximately1.5 myr ago the distance between the trajectories of these two groupings was minimal.

关键词： stars distances-stars kinematics and dynamics-galaxies star formation

RANKL inhibition reduces lesional cellularity and Gαs variant expression and enables osteogenic maturation in fibrous dysplasia

在线全文

学校读者我要写书评

暂无评论

Bone Research 2024年第1期12卷 165-179页

作者： Luis F.de Castro Jarred m.Whitlock Zachary michel Kristen Pan Jocelyn Taylor vivian Szymczuk Brendan Boyce Daniel martin vardit Kram Rebeca Galisteo Kamran melikov Leonid v.Chernomordik michael T.Collins Alison m.Boyce Skeletal Disorders and mineral Homeostasis Section National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaMDUSA Section on membrane Biology Eunice Kennedy Shriver National Institute of Child Health and Human DevelopmentNational Institutes of HealthBethesdaMDUSA metabolic Bone Disorders Unit National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaMDUSA Department of Plastic and Reconstructive Surgery The Johns Hopkins Medical InstitutionsBaltimoreMDUSA Department of Pathology and Laboratory medicine University of Rochester Medical CenterRochesterNYUSA NIDCR Genomics and Computational Biology Core National Institute of Dental and Craniofacial ResearchNational Institutes of HealthBethesdaMDUSA

Fibrous dysplasia(FD)is a rare,disabling skeletal disease for which there are no established *** evidence supports inhibiting the osteoclastogenic factor receptor activator of nuclear kappa-B ligand(RANKL)as a potential treatment *** this study,we investigated the mechanisms underlying RANKL inhibition in FD tissue and its likely indirect effects on osteoprogenitors by evaluating human FD tissue pre-and post-treatment in a phase 2 clinical trial of denosumab(NCT03571191)and in murine in vivo and ex vivo preclinical *** analysis of human and mouse tissue demonstrated increased osteogenic maturation,reduced cellularity,and reduced expression of the pathogenic Gαs variant in FD lesions after RANKL *** sequencing of human and mouse tissue supported these *** interaction between osteoclasts and mutant osteoprogenitors was further assessed in an ex vivo lesion model,which indicated that the proliferation of abnormal FD osteoprogenitors was dependent on *** results from this study demonstrated that,in addition to its expected antiosteoclastic effect,denosumab reduces FD lesion activity by decreasing FD cell proliferation and increasing osteogenic maturation,leading to increased bone formation within *** findings highlight the unappreciated role of cellular crosstalk between osteoclasts and preosteoblasts/osteoblasts as a driver of FD pathology and demonstrate a novel mechanism of action of denosumab in the treatment of bone disease.

关键词： dysplasia treatment finding

Cross-method Analysis of Corotation Radii Data Set for Spiral Galaxies

在线全文

学校读者我要写书评

暂无评论

Research in Astronomy and Astrophysics 2024年第7期24卷 95-110页

作者： v.S.Kostiuk A.A.marchuk A.S.Gusev Sternberg Astronomical Institute Lomonosov Moscow State UniversityUniversitetsky pr.13119234 MoscowRussia Central(Pulkovo)Astronomical Observatory Russian Academy of SciencesPulkovskoye chaussee 65/1196140 St.PetersburgRussia Saint Petersburg State University Universitetsky pr.28198504 St.PetersburgRussia

A corotation radius is a key characteristic of disk galaxies that is essential to determine the angular speed of the spiral structureΩ_p,and therefore understand its *** the literature,there are plenty of methods to estimate this value,but do these measurements have any consistency?In this work,we collected a data set of corotation radius measurements for 547 galaxies,300 of which had at least two *** initial analysis reveals that most objects have rather inconsistent corotation radius ***,a significant fraction of galactic disks is distinguished by a large error coverage and almost uniform distribution of *** findings do not have any relation to spiral type,Hubble classification,or presence of a *** other reasons,obtained results could be explained by the transient nature of spirals in a considerable part of *** have made our collected data sample publicly available,and have demonstrated on one example how it could be useful for future research by investigating a winding time value for a sample of galaxies with possible multiple spiral arm patterns.

关键词： galaxies fundamental parameters-galaxies kinematics and dynamics-galaxies structure

Crafting chirality in three dimensions via a novel fabrication technique for bound states in the continuum metasurfaces

在线全文

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第3期13卷 390-392页

作者： Zaid Haddadin Anna my Nguyen Lisa v.Poulikakos Department of Electrical&Computer Engineering University of California San DiegoLa JollaCAUSA Department of mechanical&Aerospace Engineering University of California San DiegoLa JollaCAUSA Program of materials Science&Engineering University of California San DiegoLa JollaCAUSA

An additional deposition step was added to a multi-step electron beam lithographic fabrication process to unlock the height dimension as an accessible parameter for resonators comprising unit cells of quasi-bound stat... 详细信息

关键词： dimensions dimension intrinsic

Formation of diffuse and spark discharges between two needle electrodes with the scattering of particles

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Plasma Science and Technology 2024年第9期26卷 32-39页

作者： victor F TARASENKO Dmitry v BELOPLOTOv Alexei N PANCHENKO Dmitry A SOROKIN Institute of High Current Electronics Siberian BranchRussian Academy of SciencesTomsk 634055Russia National Research Tomsk State University Tomsk 634050Russia

The development of a nanosecond discharge in a pin-to-pin gap filled with air at atmospheric pressure has been studied with high temporal and spatial resolutions from a breakdown start to the spark *** and negative nanosecond voltage pulses with an amplitude of tens of kilovolts were ***-resolved images of the discharge development were taken with a fourchannel Intensified Charge Coupled Device(ICCD)*** minimum delay between the camera channels could be as short as≈0.1 *** made it possible to study the gap breakdown process with subnanosecond *** was observed that a wide-diameter streamer develops from the high-voltage pointed *** ionization processes near the grounded pin electrode started when the streamer crossed half of the *** bridging the gap by the streamer,a diffuse discharge was *** development of spark leaders from bright spots on the surface of the pointed electrodes was observed at the next *** was found that the rate of development of the spark leader is an order of magnitude lower than that of the wide-diameter *** thin luminous tracks were observed against the background of a discharge plasma *** has been established that the tracks are adjacent to brightly glowing spots on the electrodes and are associated with the flight of small particles.

关键词： needle electrodes short voltage pulses atmospheric air streamer breakdown diffuse and spark discharges scattering metal particles

In vivo femtosecond laser nanosurgery of the cell wall enabling patch-clamp measurements on filamentous fungi

在线全文

学校读者我要写书评

暂无评论

microsystems & Nanoengineering 2024年第2期10卷 251-267页

作者： Tanja Pajić Katarina Stevanović Nataša v.Todorović Aleksandar J.Krmpot miroslav Živić Svetlana Savić-Šević Steva m.Lević marina Stanić Dejan Pantelić Brana Jelenković mihailo D.Rabasović Institute of Physiology and Biochemistry“Ivan Djaja” Faculty of BiologyUniversity of BelgradeStudentski trg 1611158BelgradeSerbia Institute for Biological Research“Siniša Stanković” University of BelgradeNational Institute of the Republic of SerbiaBulevar Despota Stefana 14211000BelgradeSerbia Institute of Physics Belgrade University of BelgradeNational Institute of the Republic of SerbiaPregrevica 11811080BelgradeSerbia University of Belgrade Faculty of AgricultureNemanjina Street 611080BelgradeSerbia Institute for multidisciplinary Research University of BelgradeKneza Višeslava 111030BelgradeSerbia

Studying the membrane physiology of filamentous fungi is key to understanding their interactions with the environment and crucial for developing new therapeutic strategies for disease-causing ***,their plasma membrane has been inaccessible for a micron-sized patch-clamp pipette for pA current recordings due to the rigid chitinous cell ***,we report the first femtosecond IR laser nanosurgery of the cell wall of the filamentous fungi,which enabled patch-clamp measurements on protoplasts released from hyphae.A reproducible and highly precise(diffraction-limited,submicron resolution)method for obtaining viable released protoplasts was *** release from the nanosurgery-generated incisions in the cell wall was achieved from different regions of the *** plasma membrane of the obtained protoplasts formed tight and high-resistance(GΩ)contacts with the recording *** entire nanosurgical procedure followed by the patch-clamp technique could be completed in less than 1 *** to previous studies using heterologously expressed channels,this technique provides the opportunity to identify new ionic currents and to study the properties of the ion channels in the protoplasts of filamentous fungi in their native environment.

关键词： patch recording laser

Interatomic Interaction models for magnetic materials:Recent Advances

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Physics Letters 2024年第6期41卷 54-66页

作者： Tatiana S.Kostiuchenko Alexander v.Shapeev Ivan S.Novikov Emanuel Institute of Biochemical Physics RAS 4 Kosygin StreetMoscow119334Russian Federation Independent investigator

Atomistic modeling is a widely employed theoretical method of computational materials *** has found particular utility in the study of magnetic ***,magnetic empirical interatomic potentials or spinpolarized density functional theory(DFT)served as the primary models for describing interatomic interactions in atomistic simulations of magnetic ***,in recent years,a new class of interatomic potentials known as magnetic machine-learning interatomic potentials(magnetic mLIPs)has *** mLIPs combine the computational efficiency,in terms of CPU time,of empirical potentials with the accuracy of DFT *** this review,our focus lies on providing a comprehensive summary of the interatomic interaction models developed specifically for investigating magnetic *** also delve into the various problem classes to which these models can be ***,we offer insights into the future prospects of interatomic interaction model development for the exploration of magnetic materials.

关键词： materials interaction empirical

Why lowland riparian trees are difficult to use for streamflow reconstruction

在线全文

学校读者我要写书评

暂无评论

Journal of Forestry Research 2024年第3期35卷 219-230页

作者： Xiaomei Peng Shengchun Xiao Bao Yang Quanyan Tian vladimir v.Shishov Key Laboratory of Ecological Safety and Sustainable Development in Arid Lands Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou 730000People's Republic of China School of Geography and Ocean Science Nanjing UniversityNanjing 210023People's Republic of China Institute of Fundamental Biology and Biotechnology Siberian Federal UniversityKrasnoyarskRussia 660041

Existing streamflow reconstructions based on tree-ring analysis mostly rely on species from upland,mainly montane areas,while lowland species(generally plain)areas are rarely *** limits the understanding of streamflow change history in the lowlands,which is an important basis for water resource *** study focused on Populus euphratica stands located along the main stream,eastern and western tributaries in the lower reaches of the Heihe River basin(HRb),in arid northwestern *** investigated how streamflow regulation interferes with ripar-ian trees in lowlands when they used for streamflow ***-ring width chronologies were developed and analyzed in conjunction with meteorological and hydrologic observation *** results show streamflow regulation leads in sharp fluctuations in the streamflow allocation between the eastern tributaries and western *** resulted in instability of the correlation between streamflow at the two tributaries and at the Zhengyixia hydrologic station,with corresponding fluctuations in radial growth of poplar trees on the banks of the two tributaries and at the *** regulation altered the natural patterns of seasonal streamflow below the station,changing the time window of poplar *** study provides useful insight into tree-ring width based streamflow reconstruction in the lowlands.

关键词： Tree-ring width-Dendrochronology Populus euphratica The Ejina Oasis Streamflow