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Highly efficient Nd:(La_xGd_(1-x))_3Gd_5O_(12) laser operation at 1.33 μm

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Chinese Optics Letters 2016年第2期14卷 51-54页

作者：贾志泰尹延如杨合张百涛何京良 mauro tonelli 陶绪堂 State Key Laboratory of Crystal materials Shandong University Key Laboratory of Functional Crystal materials and Device (Shandong University Ministry of Education) NEST-CNR and Dipartimento di Fisica Università di Pisa

The continuous wave （CW） and passively Q-switched （PQS） performances of diode-pumped Nd：（LaxGd1-x）3Gd5O12 （Nd：LaGGG） at 1.33 μm are achieved for the first time to our knowledge. The maximum CW output power of 5.1 W is obtained with the optical-optical conversion efficiency of 25.3% and the slope efficiency of 26.6%. In the PQS operation, by using the V3＋：YAG crystal as the saturable absorber, the maxi- mum average output power, shortest pulse width, largest pulse energy, and highest peak power are measured to be 1.1 W, 27.54 ns, 75.78 μJ, and 2.44 kW, respectively.

关键词： Optics Physics

Comparison of Wirsung-jejunal duct-tomucosa and dunking technique for pancreatojejunostomy after pancreatoduodenectomy

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Hepatobiliary & Pancreatic Diseases International 2005年第3期4卷 450-455页

作者： Unita di Chirurgia, Dipartimento di Fisiopatologia Clinica (Batignani G, Fratini G, Zuckermann m and tonelli F) and Dipartimento di Statistica (Bianchini E), Universitd degli Studi di Firenze, Flo rence, Italy Unita di Chirurgia-Dipartimento di Fisiopatologia Clinica Universita degli Studi di Firenze Viale GB Morgagni 85 50134-Firenze Italy. giacomo.batignani@unifi.it

Pancreato-enteric reconstruction after pancreatoduodenectomy (PD) is still a source of debate because of the high incidence of complications. Among the various types of pancreato-jejunostomies we don't know yet which is the best in terms of anastomotic failure and related complications rates. Wirsung-jejunal duct-to-mucosa anastomosis (WJ) and 'dunking' pancreato-jejunal anastomosis (DPJ) are the two most used ones worldwide but conflicting results are reported. To determine which is the safer anastomosis and to define when an anastomosis should be preferred, we retrospectively reviewed two groups of patients who underwent WJ or DPJ. mETHODS:Twenty-three patients underwent PD with WJ (n=17) with dilated (WJD) (n=9) or not-dilated Wirsung's duct (WJND) (n=8) or with a DPJ (n=6) over a 3-year period at a single institution. RESULTS: The complications rate was high in all groups of patients (33.3% in WJD, 37.5% in WJND and 66.7% in DPJ). A pancreatic fistula developed in one patient in each group (11. 1% in WJD, 12. 5% in WJND and 16. 7% in DPJ). All these patients were managed conservatively. Anastomotic disruption took place in the WJ patients especially in the WJND group (n=2) compared to the WJD (n=1) (25% vs 11.1%) or DPJ groups (0%) : these three patients required a re-operation. Overall, the anastomotic defects were higher in patients who underwent WJND (37.5%), compared to WJD (22.2%) and to DPJ (16.7%). However, no statistical differences were found among the groups. Delayed gastric emptying (DGE) and total parenteral nutrition (TPN) along with anastomotic defects were responsible for a prolonged hospital stay. CONCLUSIONS:Our results were not able to demonstrate any statistical difference between the two different techniques in preventing anastomotic failure. WJ can represent a valid choice in case of a dilated duct and a firm, fibrotic enlarged gland that could not be properly invaginated in a small jejunal loop. DGE may occur in those patients who experienc

关键词： pancreatoduodenectomy pancreas jejunal anastomosis Wirsung

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钢包和中间包内衬耐火材料与碳钢的化学反应

世界钢铁 2012年第4期12卷 34-41页

作者： F Cirilli A mazzarano m.tonelli 沈钟铭意大利材料研究中心

在有些情况下,对钢产品内部质量的影响并不取决于生产过程中的误操作,而是低估了液态钢水与不同工序中接触到的材料间的化学反应。尤其是在铸锭生产中,这一点尤为明显。讨论了钢包与中间包内衬耐材与普碳钢间发生的化学反应。这些试验... 详细信息

在有些情况下,对钢产品内部质量的影响并不取决于生产过程中的误操作,而是低估了液态钢水与不同工序中接触到的材料间的化学反应。尤其是在铸锭生产中,这一点尤为明显。讨论了钢包与中间包内衬耐材与普碳钢间发生的化学反应。这些试验涉及高铝质、铝硅质、铝镁尖晶石质耐火材料,研究了它们在液态钢水中形成夹杂物的倾向性。试验结果表明,在钢水—耐材接触面上会产生一个富含mnO的新相,这一新相的量与二氧化硅在耐材中的活性及锰在钢液里的活性成正比。试验还表明,由液态钢水与耐火材料相互反应产生的接触面可产生新的外来夹杂物进入钢液中。试验结束后,对钢样中新的夹杂物成分做的分析表明,成分取决于耐材—钢水接触面的组成。因此,不同钢厂应该结合自身生产的钢种产品化学组成来选用耐火材料的化学成分设计。

关键词：耐火材料钢锭夹杂物二氧化硅氧化铝

冠状动脉疾病患者的蛋白尿、受损肾功能和不良预后:对一项先前进行的随机试验的分析

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世界核心医学期刊文摘（心脏病学分册） 2007年第3期3卷 1-2页

作者： tonelli m. Jose P. Curhan G. 郭俊 Prof.Department of medicine University of AlbertaEdmontonAlta.T6G2C3Canada

目的:确定蛋白尿资料是否有助于改进仅依据肾功能的风险评估,肾功能检测结果是否是对蛋白尿资料的有力补充。设计:对一项随机试验的资料进行分析。肾功能受损的定义为低肾小球滤过率[<60ml/(min·1.73m2)]和浸渍片尿液分析为蛋白尿(≥1... 详细信息

目的:确定蛋白尿资料是否有助于改进仅依据肾功能的风险评估,肾功能检测结果是否是对蛋白尿资料的有力补充。设计:对一项随机试验的资料进行分析。肾功能受损的定义为低肾小球滤过率[ml/(min·1.73m2)]和浸渍片尿液分析为蛋白尿(≥1+蛋白)。

关键词：肾功能低肾小球滤过率尿液分析随机试验心肌梗死病史全因死亡普伐他汀风险评估心血管事件

早发非波动性脊髓小脑共济失调与CACNA1A基因的一种新错义突变

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世界核心医学期刊文摘(神经病学分册) 2006年第4期 54-55页

作者： tonelli A. D'Angelo m.G. Salati R. 刘凯 IRCCS Eugenio medea Via don Luigi Monza 20 Bosisio Parini Lecco Italy

mutations in the brain-specific P/Q type Ca2+ channel α 1 subunit gene, CACNA1A, have been identified in three clinically distinct disorders, spinocerebellar ataxia type 6 (SCA6), episodic ataxia type 2 (EA2), and familial hemiplegic migraine type 1 (FHm1). SCA6 is associated with small expansions of a CAG repeat at the 3′ end of the gene, while point mutations are mostly responsible for its two allelic disorders, FHmI and EA2. From the electrophysiological point of view, while FHmI mutations lead to a gain of function [Tottene A, Fellin T, Pagnutti S, Luvisetto S, Striessnig J, Fletcher C, et al. Familial hemiplegic migraine mutations increase Ca(2+ ) influx through single human CaV2.1 channels and decrease maximal CaV2.1 current density in neurons. Proc Natl Acad Sci 99 (20)- (2002) 13284- 13289.], EA2 mutations usually generate a loss of channel function [Guida S, Trettel F, Pagnutti S, mantuano E, Tottene A, Veneziano L, et al. Complete loss of P/Q calcium channel activity caused by a CACNA1A missense mutation carried by patients with episodic ataxia type 2. Am J Hum Genet 68 (3) (2001) 759- 764, WapplE, Koschak A, Poteser m, Sinnegger mJ, Walter D, Eberhart A, et al. Functional consequences of P/Q-type Ca2+ channel Cav2.1 missense mutations associated with episodic ataxia type 2 and progressive ataxia. J Biol Chem 277 (9) (2002) 6960- 6966.]. In the present study, we describe a child affected by permanent non-fluctuating limb and trunk ataxia with a quite early age of onset. Interestingly, the size of the CACNA1A triplet repeat region in the patient is within the normal range while he carries a novel de novo missense mutation in this gene, p.R1664Q. Although functional data are not available, based on the literature data indicating that severe reductions in P/Q-type channel activity favour episodic and/or progressive ataxic symptoms [Wappl E, Koschak A, Poteser m, Sinnegger mJ, Walter D, Eberhart A, et al. Functional consequences of P/Q type Ca2+ channel Cav2.1

关键词：共济失调运动失调神经系统疾病脊髓小脑 CACNA1A 波动性基因

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掺铥氟化钇钡晶体光谱性能研究

掺铥氟化钇钡晶体光谱性能研究

中国光学学会2010年光学大会

作者：李春张学建张莹董仲伟 mauro.tonelli 刘景和长春理工大学材料科学与工程学院吉林建筑工程学院外事处 NEST-NanoscienceInstitute-CNR and Dipartimento di Fisica Universita'Di Pisa Largo B.Pontecorvo356127PisaItaly

采用提拉法,生长掺铥氟化钇钡[分子式:Tm3+:BaY2F8,简称Tm:BYF]激光晶体。工艺参数:拉速0.5mm/h,转速5rad/min,冷却速率10℃/h。XRD分析表明:晶体属于单斜晶系,空间群C12/m1,计算的晶胞参数:a=6.9928 A,b=10.5293A,c=4.2751A,β=99.69°。测试了晶体的吸收及荧光光谱,在791nm处的半高宽是42nm,计算此处的吸收系数和吸收截面分别为4.56cm-1,7.77×10-21cm2。Tm:BYF晶体在1879.6nm附近有很强的荧光发射峰,半高宽为79nm,发射截面为2.13×10-21cm2,荧光寿命为8.7ms,有利于Tm:BYF晶体实现2μm激光输出。

关键词：掺铥氟化钇钡激光晶体提拉法吸收光谱荧光光谱

来源： cnki会议评论

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大型发电厂凝汽器酸洗时的防腐问题

清洗世界 1989年第S1期13卷 41-44页

作者： R.Cigna S.Di Simone G.Gusmano R.tonelli 马奇

由于循环清洗液的量大,且材料种类繁多,如果铜管表面上又粘附着各种氧化物,则酸洗大型发电厂铜合金凝汽管束的过程中将涉及许多问题。因清洗液中有三价铁离子,碳铜和铝铜合金两者的腐蚀率都非常高,为此加入缓蚀剂以抑制三价铁离子的作用... 详细信息

由于循环清洗液的量大,且材料种类繁多,如果铜管表面上又粘附着各种氧化物,则酸洗大型发电厂铜合金凝汽管束的过程中将涉及许多问题。因清洗液中有三价铁离子,碳铜和铝铜合金两者的腐蚀率都非常高,为此加入缓蚀剂以抑制三价铁离子的作用,并将碳钢的腐蚀率由20mm/y以上降低到2mm/y,铝铜合金的腐蚀率由数mm/y降低到20～30μm/y。但是,缓蚀剂的加入给清洗过程终点的判断带来了不便。由于配制和排放清洗液的时间较长,且在这种大型凝汽器中清洗液流速较低,所以还必须把清洗时问考虑进去。本文以不同浓度、流速的盐酸及硫酸溶液在同一试验装置中进行试验,并应用了电化学技术,测定了腐蚀电位及线性极化电阻,以判断清洗过程的终点。

关键词：大型发电厂铝铜合金酸洗过程腐蚀率三价铁离子硫酸溶液凝汽器管腐蚀电位清洗过程电化学技术

治疗高血压的医疗保健费用:一项基于加拿大人口的队列研究

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中华高血压杂志 2015年第7期23卷 666-666页

作者：李金凤叶鹏 Weaver CG Clement Fm Campbell NR James mT Klarenbach SW Hemmelgarn BR tonelli m mcBrien KA

准确地记录目前以及未来治疗高血压的费用对于全面认识现行乃至未来防治高血压的干预措施对经济的潜在作用至关重要。该研究旨在评估加拿大目前治疗高血压的医疗保健费用并预测至2020年的相应治疗费用。通过2002-2010年加拿大Alberta省... 详细信息

准确地记录目前以及未来治疗高血压的费用对于全面认识现行乃至未来防治高血压的干预措施对经济的潜在作用至关重要。该研究旨在评估加拿大目前治疗高血压的医疗保健费用并预测至2020年的相应治疗费用。通过2002-2010年加拿大Alberta省（居民〉300万）人群管理数据鉴别个体是否患有高血压。

关键词：医疗保健费用治疗费用高血压加拿大队列研究人口潜在作用干预措施

Tm,Ho：BaY2F8晶体光谱性能与能量传递

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无机化学学报 2011年第1期27卷 6-10页

作者：李春张学建王成伟张莹董仲伟 mauro Tonell 刘景和长春理工大学材料科学与工程学院长春130022 吉林建筑工程学院外事处长春130021 NEST-CNR and Dipartimento di Fisica Universita di PisaLargo B.Pontecorvo 356127 PisaItaly

采用提拉法,生长钬铥双掺氟化钇钡[分子式:Tm3+,Ho3+∶BaY2F8,简称Tm,Ho∶BYF]激光晶体。工艺参数:拉速0.5 mm.h-1,转速5 ***-1,冷却速率10℃.h-1。XRD表明:属于单斜晶系,空间群C12/m1。计算出晶格参数:a=0.69973 nm,b=1.05293 nm,c=0.427 84 nm,β=99.71°。测试了晶体的吸收及荧光光谱,同时计算了784 nm处吸收峰的半高宽、吸收系数及吸收截面,分别为3.2 nm,2.23 cm-1,7.44×10-21 cm2。该吸收峰对应于Tm3+离子从基态3H6到激发态3H4的跃迁。Tm,Ho∶BYF晶体在2.06μm附近有很强的荧光发射峰,在该荧光峰的发射截面和荧光寿命分别为4.96×10-21 cm2,10.1 ms。Tm3+→Ho3+的正向、反向能量转换系数之比是10.4。

关键词：钬铥双掺氟化钇钡晶体吸收光谱荧光光谱能量传递