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Approach to traumatic cardiac arrest in the emergency department: a narrative literature review for emergency providers

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World Journal of Emergency medicine 2024年第1期15卷 3-9页

作者： Rashed Alremeithi Quincy K.Tran megan T.Quintana soroush Shahamatdar Ali Pourmand Department of Emergency medicine George Washington University School of Medicine and Health SciencesWashington DC 20037USA Department of Emergency medicine University of Maryland School of MedicineBaltimore 21201USA Program in Trauma the R Adams Cowley Shock Trauma CenterUniversity of Maryland School of MedicineBaltimore 21201USA Center for Trauma and Critical Care Department of Surgerythe George Washington University School of Medicine&Health SciencesWashington DC 20037USA

BACKGROUND:Traumatic cardiac arrest(TCA)is a major contributor to mortality and morbidity in all age groups and poses a significant burden on the healthcare *** there have been advances in treatment modalities,survival rates for TCA patients remain *** narrative literature review critically examines the indications and eff ectiveness of current therapeutic approaches in treating ***:We performed a literature search in the Pubmed and Scopus databases for studies published before December 31,*** search was refi ned by combining search terms,examining relevant study references,and restricting publications to the English *** the search,943 articles were retrieved,and two independent reviewers conducted a screening ***:A review of various studies on pre-and intra-arrest prognostic factors showed that survival rates were higher when patients had an initial shockable *** were conflicting results regarding other prognostic factors,such as witnessed arrest,bystander cardiopulmonary resuscitation(CPR),and the use of prehospital or in-hospital *** thoracotomy was found to result in more favorable outcomes in cases of penetrating trauma than in those with blunt *** endovascular balloon occlusion of the aorta(REBOA)provides an advantage to emergency thoracotomy in terms of occupational safety for the operator as an alternative in managing hemorrhagic *** implemented in the setting of aortic occlusion,emergency thoracotomy and REBOA resulted in comparable mortality ***-venous extracorporeal life support(V-V ECLS)and veno-arterial extracorporeal life support(V-A ECLS)are viable options for treating respiratory failure and cardiogenic shock,*** the context of traumatic injuries,V-V ECLS has been associated with higher rates of survival to discharge than V-A ***:TCA remains a signifi cant challenge for emergency medical services due to its high m

关键词： Traumatic cardiac arrest Emergency thoracotomy Resuscitative endovascular balloon occlusion of the aorta

Experimental study on nanoparticles-assisted low-salinity water for enhanced oil recovery in asphaltenic oil reservoirs

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Petroleum 2023年第3期9卷 395-402页

作者： Ali Amraeiniya soroush Shojaei Amir Ali mohseni Behzad Haj Abbasi mahani Sogand Saatchi Arash Barahooie Bahari Seyyed mohammad mousavi Sisakht Department of Petroleum Engineering Faculty of EngineeringIslamic Azad UniversityTehranIran Department of Petroleum Engineering Semnan UniversitySemnanIran Department of Chemistry and Chemical Engineering Rasht BranchIslamic Azad UniversityRashtIran Department of Petroleum Engineering Lamerd Higher Education CenterLamerdIran

The purpose of this research is to look into the augmentation of silica nanoparticles(NPs)with low salinity(LowSal)brine for EOR.A series of analyses,including oil/water interfacial tension(IFT)and rock wettability tests were undertaken to determine an optimal dispersion to flood into a porous carbonate core with a defined pore size *** 60℃and 14.5 psi,the maximum drop(i.e.,roughly 12.5 mN/m)in oil/water IFT by 0.3 wt%brine occurred,but when 0.08 wt%silica was added to the brine,the IFT reduced to 14.51 mN/m at 60℃and 14.5 *** wettability analysis revealed a significant reduction in contact angle,from 142°to 72°and 59°,using 0.04 and 0.08 wt%silica in LowSal brine,but the extent reduced by brine alone was *** results of rock pore size characterization were discussed in terms of the accomplishment of operating EOR in the porous medium in the presence of *** addition of 0.08 wt%silica to the injected brine resulted in an additional oil recovery of 16.3%OOIP as well as a significant shift in the endpoints/cross-points of the oil/water relative permeability *** findings of this research might help improve oil recovery from asphaltenic oil reservoirs or,more environmentally friendly,remediate petroleum crude-oil polluted soil.

关键词： Silica nanoparticles Low salinity brine Enhanced oil recovery Carbonate Relative permeability

Targeted chemotherapy via HER2-based chimeric antigen receptor(CAR)engineered T-cell membrane coated polymeric nanoparticles

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Bioactive materials 2024年第4期34卷 422-435页

作者： Serkan Yaman Harish Ramachandramoorthy Priyanka Iyer Uday Chintapula Tam Nguyen manoj Sabnani Tanviben Kotadia soroush Ghaffari Laurentiu m.Pop Raquibul Hannan Jon A.Weidanz Kytai T.Nguyen Department of Bioengineering University of Texas at ArlingtonTXUSA Department of Biology University of Texas at ArlingtonTXUSA Joint Bioengineering Program University of Texas Southwestern Medical CenterTXUSA Department of Radiation Oncology University of Texas Southwestern Medical CenterTXUSA Department of Kinesiology University of Texas at ArlingtonArlingtonTXUSA

Cell membrane-derived nanoparticles(NPs)have recently gained popularity due to their desirable features in drug delivery such as mimicking properties of native cells,impeding systemic clearance,and altering foreign body *** NP technology,adoptive immunotherapy has emerged due to its promise in cancer specificity and therapeutic *** this research,we developed a biomimetic drug carrier based on chimeric antigen receptor(CAR)transduced T-cell *** that purpose,anti-HER2 CAR-T cells were engineered via lentiviral transduction of anti-HER2 CAR coding lentiviral ***-HER2 CAR-T cells were characterized by their specific activities against the HER2 antigen and used for cell membrane ***-cancer drug Cisplatin-loaded poly(D,L-lactide-co-glycolic acid)(PLGA)NPs were coated with anti-human epidermal growth factor receptor 2(HER2)-specific CAR engineered T-cell ***-HER2 CAR-T-cell membrane-coated PLGA NPs(CAR-T-mNPs)were characterized and confirmed via fluorescent microscopy and flow ***-coated NPs showed a sustained drug release over the course of 21 days in physiological ***-loaded CAR-T-mNPs also inhibited the growth of multiple HER2+cancer cells in *** addition,in vitro uptake studies revealed that CAR-T-mNPs showed an increased uptake by A549 *** results were also confirmed via in vivo biodistribution and therapeutic studies using a subcutaneous lung cancer model in nude ***-T-mNPs localized preferentially at tumor areas compared to those of other studied groups and consisted of a significant reduction in tumor growth in tumor-bearing *** Conclusion,the new CAR modified cell membrane-coated NP drug-delivery platform has demonstrated its efficacy both in vitro and in ***,CAR engineered membrane-coated NP system could be a promising cell-mimicking drug carrier that could improve therapeutic outcomes of lung cancer treatments.

关键词： Nanoparticles CAR-T cells membrane-based drug delivery Cancer chemotherapy

Phase change materials as quenching media for heat treatment of 42Crmo4 steels

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Journal of Central South University 2020年第3期27卷 752-761页

作者： milad SAKKAKI Farhad SADEGH mOGHANLOU soroush PARVIZI Haniyeh BAGHBANIJAVID Aziz BABAPOOR mehdi SHAHEDI ASL Department of mechanical Engineering University of Mohaghegh ArdabiliArdabilIran Department of materials Engineering Shahid Rajaee Teacher Training UniversityLavizanTehranIran Department of Chemical Engineering University of Mohaghegh ArdabiliArdabilIran

In the present work,paraffin phase change material is used as quenchant for the heat treatment of 42Crmo4 alloy and compared with water,air,and CuO doped *** samples were prepared based on ASTm E 8m-98 standard for tensile test and then heated up to 830°C,kept for 4 h in an electric resistance furnace and then quenched in the mentioned *** modulus,yield strength,ultimate tensile strength,elongation,and modulus of toughness were determined according to the obtained stress?strain ***,the hardness and microstructural evolution were investigated after the heat treatment at different *** samples quenched in paraffin and CuO-doped paraffin are higher in ultimate tensile strength(1439 and 1306 mPa,respectively)than those quenched in water(1190 mPa)and air(1010 mPa).The highest hardness,with a value of HV 552,belonged to the sample quenched in CuO-doped *** microstructural studies revealed that the non-tempered steel had a ferrite/pearlite microstructure,while by quenching in water,paraffin and CuO-doped paraffin,ferrite/martensite microstructures were *** is also observed that using the air as quenchant resulted in a three-phase bainite/martensite/ferrite microstructure.

关键词： phase change materials heat treatment quenchant 42Crmo4 steel microstructure mechanical property

Augmenting prostate magnetic resonance imaging reporting to incorporate diagnostic recommendations based upon clinical risk calculators

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World Journal of Radiology 2022年第8期14卷 249-255页

作者： Karisma Gupta Jordan D Perchik Andrew m Fang Kristin K Porter soroush Rais-Bahrami Department of Radiology University of WashingtonSeattleWA 98195United States Department of Radiology University of Alabama at BirminghamBirminghamAL 35233United States Department of Urology University of Alabama at BirminghamBirminghamAL 35233United States O'Neal Comprehensive Cancer Center University of Alabama at BirminghamBirminghamAL 35233United States

Risk calculators have offered a viable tool for clinicians to stratify patients at risk of prostate cancer(PCa)and to mitigate the low sensitivity and specificity of screening prostate specific antigen(PSA).While initially based on clinical and demographic data,incorporation of multiparametric magnetic resonance imaging(mRI)and the validated prostate imaging reporting and data system suspicion scoring system has standardized and improved risk stratification beyond the use of PSA and patient parameters ***-naïve patients with lower risk profiles for harboring clinically significant PCa are often subjected to uncomfortable,invasive,and potentially unnecessary prostate biopsy *** risk calculator data into prostate mRI reports can broaden the role of radiologists,improve communication with clinicians primarily managing these patients,and help guide clinical care in directing the screening,detection,and risk stratification of PCa.

关键词： Prostatic adenocarcinoma multiparametric magnetic resonance imaging Nomograms Risk calculators Biopsy

Surface-illuminated photon-trapping high-speed Ge-on-Si photodiodes with improved efficiency up to 1700 nm

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Photonics Research 2018年第7期6卷 734-742页

作者： HILAL CANSIZOGLU CESAR BARTOLO-PEREZ YANG GAO EKATERINA PONIZOVSKAYA DEVINE soroush GHANDIPARSI KAZIm G.POLAT HASINA H.mAmTAZ TOSHISHIGE YAmADA ALY F.ELREFAIE SHIH-YUAN WANG m.SAIF ISLAm Electrical and Computer Engineering University of California-Davis W&WSens Devices Inc. Electrical Engineering Baskin School of Engineering University of CaliforniaSanta Cruz

In this paper, high-speed surface-illuminated Ge-on-Si pin photodiodes with improved efficiency are demonstrated. With photon-trapping microhole features, the external quantum efficiency(EQE) of the Ge-on-Si pin diode is >80% at 1300 nm and 73% at 1550 nm with an intrinsic Ge layer of only 2 μm thickness, showing much improvement compared to one without microholes. more than threefold EQE improvement is also observed at longer wavelengths beyond 1550 nm. These results make the microhole-enabled Ge-on-Si photodiodes promising to cover both the existing C and L bands, as well as a new data transmission window(1620–1700 nm),which can be used to enhance the capacity of conventional standard single-mode fiber cables. These photodiodes have potential for many applications, such as inter-/intra-datacenters, passive optical networks, metro and longhaul dense wavelength division multiplexing systems, eye-safe lidar systems, and quantum *** CmOS and Bi CmOS monolithic integration compatibility of this work is also attractive for Ge CmOS,near-infrared sensing, and communication integration.

关键词：锗硅光电二极管通讯技术理论分析

Achieving higher photoabsorption than groupⅢ-Ⅴsemiconductors in ultrafast thin silicon photodetectors with integrated photon-trapping surface structures

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Advanced Photonics Nexus 2023年第5期2卷 33-43页

作者： Wayesh Qarony Ahmed S.mayet Ekaterina Ponizovskaya Devine soroush Ghandiparsi Cesar Bartolo-Perez Ahasan Ahamed Amita Rawat Hasina H.mamtaz Toshishige Yamada Shih-Yuan Wang m.Saif Islama University of California DavisDepartment of Electrical and Computer EngineeringDavisCaliforniaUnited States W&WSens Devices Inc.Los AltosCaliforniaUnited States University of California Baskin School of EngineeringDepartment of Electrical and Computer EngineeringSanta CruzCaliforniaUnited States

The photosensitivity of silicon is inherently very low in the visible electromagnetic spectrum,and it drops rapidly beyond 800 nm in near-infrared *** have experimentally demonstrated a technique utilizing photon-trapping surface structures to show a prodigious improvement of photoabsorption in 1-μm-thin silicon,surpassing the inherent absorption efficiency of gallium arsenide for a broad *** photon-trapping structures allow the bending of normally incident light by almost 90 deg to transform into laterally propagating modes along the silicon ***,the propagation length of light increases,contributing to more than one order of magnitude improvement in absorption efficiency in *** high-absorption phenomenon is explained by finitedifference time-domain analysis,where we show an enhanced photon density of states while substantially reducing the optical group velocity of light compared to silicon without photon-trapping structures,leading to significantly enhanced light–matter *** simulations also predict an enhanced absorption efficiency of photodetectors designed using 30-and 100-nm silicon thin films that are compatible with CmOS *** a very thin absorption layer,such photon-trapping structures can enable high-efficiency and high-speed photodetectors needed in ultrafast computer networks,data communication,and imaging systems,with the potential to revolutionize on-chip logic and optoelectronic integration.

关键词： photoabsorption photon trapping group-velocity reduction photodetectors silicon photonics