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Estimating the subsolar magnetopause position from soft X-ray images using a low-pass image filter

Earth and Planetary Physics 2024年第1期8卷 173-183页

作者： Hyangpyo Kim Hyunju K.Connor Jaewoong Jung Brian m.Walsh David Sibeck Kip D.Kuntz Frederick S.Porter Catriana K.Paw U Rousseau A.Nutter Ramiz Qudsi Rumi Nakamura michael Collier Space Research Institute Austrian Academy of Sciences8042 GrazAustria Geophysical Institute University of Alaska FairbanksFairbanksAlaska 99775USA National Aeronautics and Space Administration(NASA)Goddard Space Flight Center GreenbeltMaryland 20771USA Astronomy Department University of Maryland College ParkCollege ParkMaryland 20742USA Center for Space Physics Boston UniversityBostonMassachusetts 02215USA Department of Physics and Astronomy Johns Hopkins UniversityBaltimoreMaryland 21218USA Howard University WashingtonDC 20059USA

The Lunar Environment heliospheric X-ray Imager(LEXI)and Solar wind magnetosphere Ionosphere Link Explorer(SmILE)missions will image the Earth’s dayside magneto pause and cusps in soft X-rays after their respective launches in the near future,to specify glo bal magnetic reconnection modes for varying solar wind *** suppo rt the success of these scientific missions,it is critical to develop techniques that extract the magnetopause locations from the observed soft X-ray *** this research,we introduce a new geometric equation that calculates the subsolar magnetopause position(RS)from a satellite position,the look direction of the instrument,and the angle at which the X-ray emission is *** assumptions are used in this method:(1)The look direction where soft X-ray emissions are maximized lies tangent to the magnetopause,and(2)the magnetopause surface near the subsolar point is almost spherical and thus RSis nea rly equal to the radius of the magneto pause *** create synthetic soft X-ray images by using the Open Geospace General Circulation model(OpenGGCm)global magnetohydrodynamic model,the galactic background,the instrument point spread function,and Poisson *** then apply the fast Fourier transform and Gaussian low-pass filte rs to the synthetic images to re move noise and obtain accurate look angles for the soft X-ray pea *** the filte red images,we calculate RS and its accuracy for different LEXI locations,look directions,and solar wind densities by using the OpenGGCm subsolar magnetopause location as ground *** method estimates RS with an accuracy of10 *** accuracy improves for greater solar wind densities and during southward interplanetary magnetic *** method ca ptures the magnetopause motion during southwa rd interplaneta ry magnetic field ***,the technique will enable quantitative analysis of the magnetopause motion and help reveal the daysi

关键词： soft X-ray magnetopause reconnection low-pass filter LEXI SmILE

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Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage

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Neural Regeneration Research 2025年第9期20卷 2454-2463页

作者： Victoria Jiménez Carretero IrisÁlvarez-merz Jorge Hernández-Campano Sergei A.Kirov Jesús m.Hernández-Guijo Department of Pharmacology and Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ramón y Cajal Institute for Health Research(IryCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain Institute of Neurobiology Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neuroscience and Regenerative medicine&Department of Neurosurgery Medical College of Georgia at Augusta UniversityAugustaGAUSA

The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is ***,the role of non-excitatory amino acids in brain damage following a stroke or brain trauma remains largely *** release of amino acids by necrotic cells in the ischemic core may contribute to the expansion of the *** findings indicated that the reversible loss of field excitato ry postsynaptic potentials caused by transient hypoxia became irreversible when exposed to a mixture of just four non-excitatory amino acids(L-alanine,glycine,L-glutamine,and L-serine)at their plasma *** amino acids induce swelling in the somas of neurons and astrocytes during hypoxia,along with permanent dendritic damage mediated by N-methyl-D-aspartate *** N-methyl-D-aspartate receptors prevented neuronal damage in the presence of these amino acids during *** is likely that astroglial swelling caused by the accumulation of these amino acids via the alanine-serine-cysteine transporter 2 exchanger and system N transporters activates volume-regulated anion channels,leading to the release of excitotoxins and subsequent neuronal damage through N-methyl-D-aspartate receptor ***,previously unrecognized mechanisms involving non-excitatory amino acids may contribute to the progression and expansion of brain injury in neurological emergencies such as stroke and traumatic brain *** these pathways co uld highlight new therapeutic targets to mitigate brain injury.

关键词： cell swelling N-methyl-D-aspartate receptor non-excitatory amino acids stroke synaptic transmission

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钢铁中多元夹杂物颗粒的三维评估

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冶金分析 2012年第8期32卷 1-8页

作者： ry0 noue KEI iyokawa KOICHIRO Tomoda SHIGERU Ueda TATSURO Ariyama 日本东北大学高级材料多学科研究所日本仙台980-8577 日本东芝纳米分析有限公司物理分析技术中心日本川崎212-8583

为了从钢铁中提取各种夹杂物颗粒,考察了采用无水电解质的恒电位和恒电流的提取方法。结果认为,4%的mS[4%(V/V)甲基水杨酸-1%(m/V)水杨酸-1%(m/V)四甲基氯化铵-甲醇)和10%AA(10%(V/V)乙酰丙酮-1%(m/V)四甲基氯化铵-甲醇]电解质溶液适用... 详细信息

为了从钢铁中提取各种夹杂物颗粒,考察了采用无水电解质的恒电位和恒电流的提取方法。结果认为,4%的mS[4%(V/V)甲基水杨酸-1%(m/V)水杨酸-1%(m/V)四甲基氯化铵-甲醇)和10%AA(10%(V/V)乙酰丙酮-1%(m/V)四甲基氯化铵-甲醇]电解质溶液适用于提取钢铁中夹杂物TiOx和TiAl2O5。尽管这些电解提取法可以提取化学性能不稳定的夹杂物颗粒,然而,因为对夹杂物的观察是在萃取完成后于一个滤膜中进行,因此无法确定金属中每种夹杂物的具体位置。为了确定金属中夹杂物的具体位置,将卤-醇的光蚀刻方法用于以Ti和Al除氧的钢样品表面附近出现的夹杂颗粒,使用扫描电子显微技术和俄歇电子能谱(AES)对精细夹杂物颗粒形貌、尺寸和元素的偏析进行评估,不过卤醇却和钢铁中的金属钛和金属铝发生还原反应。对微小夹杂物颗粒的成分的形态、分离进行估测,然后,使用一种低加速能-扫描电子显微技术和俄歇电子能谱(AES)对用聚焦离子束制备微小夹杂物颗粒截面上元素的微观偏析进行评定。在这些研究结果基础上讨论了多元夹杂物颗粒的形成机理。

关键词：三维评估多元夹杂物光蚀刻俄歇电子能谱(AES) 聚焦离子束形成机理

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Evaluation of the colorectal cancer risk conferred by rare UNC5C alleles

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World Journal of Gastroenterology 2014年第1期20卷 204-213页

作者： Sébastien Küry Céline Garrec Fabrice Airaud Flora Breheret Virginie Guibert Cécile Frenard Shuo Jiao Dominique Bonneau Pascaline Berthet Céline Bossard Olivier Ingster Estelle Cauchin Stéphane Bezieau CHU Nantes Service de Génétique Médicale44093 Nantes CEDEX 1France Public Health Sciences Division Fred Hutchinson Cancer Research CenterSeattleWA 98109United States CHU Angers Service de Génétique Médicale4 rue Larrey49933 AngersFrance Centre de Lutte contre le Cancer Fran?ois Baclesse 3 avenue du Général Harris14076 Caen Cedex 5France Université de Nantes Faculté de Médecine de NantesEA 4273 NantesFrance CHU Nantes Institut des Maladies de l’Appareil Digestif et Service d’Hépato-Gastroentérologie44093 Nantes Cedex 1France

AIm: To evaluate the risk associated with variants of the UNC5C gene recently suspected to predispose to familial colorectal cancer (CRC).

关键词： Colorectal cancer UNC5C Genetic predisposition Familial study Association study Low risk

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Prevalence and Factors Associated with Virologic Failure among People Living with HIV (PLHIV) monitored in a Decentralized Health Care Facility

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Advances in Infectious Diseases 2019年第3期9卷 226-237页

作者： Selly Ba Ndeye Diama Ba Lamanatou Sembene Habibatou Dia mohamed Coulibaly Jean Louis Ndiaye Ndeye m.ry Dia Cheikh Tidiane Ndour Doctoral School of Thies University Thies Senegal Intrahealth International Dakar Senegal Roi Baudouin Hospital Dakar Senegal AIDS monitoring Unit/ministry of Health Dakar Senegal Department of Health Gaston Berger University Saint Louis Senegal

Introduction: In Senegal, the decentralization of Health Care Centers has contributed significantly to the intensification of antiretroviral treatment. However, Care providers are still facing the treatment optimizing challenge. Objectives: To determine the prevalence of virologic failures of PLHIV monitored in a decentralized Health care center and to determine associated factors. Patients and methods: This is a cross-sectional descriptive and analytical study of PLHIV, aged 18 years and over, on first-line treatment, monitored onsite from February 1st to December 31st, 2018. A data collection form was completed from medical records (clinical, immuno-virologic and evolutionary). Any VL > 1000 cp/ml after 6 months of antiretroviral therapy (ART) was considered as virologic failure. Data were captured and analysed using the EPI INFO 2002software. Chi-square test and the Fisher test were used to compare the proportions;a value of p ≤ 0.05 was considered significant. Results: 331 patients were treated with HIV-1 profile in 89% of cases. A proportion of 55% was married and 97% came from rural areas. 80% were either not or poorly educated. The median of age was 44 ± 11 years with a F/m ratio of 3.4. At baseline, 56% were symptomatic at stage 3 or 4 of WHO. They had severe immunosuppression with a median CD4 count of 217 ± 187 cells/mm3, the viral load was detectable in half of the patients with a median VL of 97,000 cp/ml ± 70,569. The antiretroviral regimen combined 2 NRTIs with 1 NNRTI in 88% of cases. The median of follow-up was estimated at 60 ± 43 months. The prevalence of virologic failure was 19%. This prevalence was associated with age less than 25 years (p = 0.04), late diagnosis (CD4 at baseline less than 200 cel/mm3 (p = 0.002), stage 3 or 4 WHO (p = 0.04) High viral load greater than 10,000 (p = 0.04) at baseline. Conclusion: These results suggest making the new therapeutic classes accessible for first-line treatment.

关键词： ART Virologic Failure Associated Factors

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基于影像组学、视觉和直方图评估证实冠状动脉CT血管成像上动脉粥样硬化病变的体外研究

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国际医学放射学杂志 2019年第6期 735-736页

作者： m.Kolossváry J.Karády Y.Kikuchi A.Ivanov C.L.Schlett m.T.Lu 许棚棚 mTA-SE Cardiovascular Imaging Research Group Heart and Vascular Center Semmelweis University

摘要目的以组织学检查确定的晚期动脉粥样硬化病变为诊断标准,在体外冠状动脉CT血管成像基础上,比较基于影像组学的机器学习方法与基于视觉和直方图评估方法

关键词：冠状动脉机器学习模型动脉粥样硬化病变 CT 影像组学体外研究直方图

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Prediction of Wearing of Cutting Tools Using Real Time machining Parameters and Temperature Using Rayleigh-Ham method

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modern mechanical Engineering 2023年第2期13卷 35-54页

作者： Jean Nyatte Nyatte Fabrice Alban Epee Wilba Christophe Kikmo Samuel Batambock Claude Valéry Ngayihi Abbe Robert Nzengwa E3m Laboratory National Higher Polytechnic School Douala University of Douala Douala Cameroon Institut Universitaire de Technologie (IUT-BOIS) University of Yaoundé I Mbalmayo Cameroon

Wear of cutting tools is a big concern for industrial manufacturers, because of their acquisition cost as well as the impact on the production lines when they are unavailable. Law of wear is very important in determining cutting tools lifespan, but most of the existing models don’t take into account the cutting temperature. In this work, the theoretical and experimental results of a dynamic study of metal machining against cutting temperature of a treated steel of grade S235JR with a high-speed steel tool are provided. This study is based on the analysis of two complementary approaches, an experimental approach with the measurement of the temperature and on the other hand, an approach using modeling. Based on unifactorial and multifactorial tests (speed of cut, feed, and depth of cut), this study allowed the highlighting of the influence of the cutting temperature on the machining time. To achieve this objective, two specific approaches have been selected. The first was to measure the temperature of the cutting tool and the second was to determine the wear law using Rayleigh-Ham dimensional analysis method. This study permitted the determination of a law that integrates the cutting temperature in the calculations of the lifespan of the tools during machining.

关键词： machining Cutting Temperature modeling Wear Cutting Tool

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多层CT Willis环成像:Willis环变异与颈动脉病变及脑缺血的相关性

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国际医学放射学杂志 2019年第2期42卷 242-243页

作者： A.Varga G.D.Leo P.V.Banga C.C.Novák m.Kolossváry P.m.Horvat 郑育聪(译) 陈秀玉(校) Department of Diagnostic Radiology Heart and Vascular CenterSemmelweis University18 Határor streetBudapest 1122Hungary 不详

目的评估颈动脉内膜剥脱术病人Willis环(CoW)的变异率,并探讨变异与对照组及CT诊断的脑缺血的相关性。方法本研究经机构伦理委员会批准,回顾性分析544例颈动脉内膜剥离术病人[男331例,平均年龄(69±8)岁]和196例对照组[男117例。

关键词：脑缺血变异率 Willis CT Willis 相关性

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Changes Induced by Physical Activity, Weight Loss and Calorie Restriction in Body Composition, Lipoproteins and Functional Capacity in Obese Congolese Women

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Health 2020年第6期12卷 548-571页

作者： moulongo Jean Georges André makosso Vheiye Georges Eouani max Lévy Em.ry mouanda Richard Le Savant Ndalla mathias Cyriaque Packa Tchissambou Bernard massamba Alphonse Laboratory of Sports Biosciences Higher Institute of Physical Education and Sports Marien NGOUABI University Brazzaville Congo Unit of Nutritional Science and metabolism Higher Institute of Physical Education and Sports Marien NGOUABI University Brazzaville Congo Department of Gynecology & Obstetrics Loandjili Hospital Pointe-Noire (Congo) and Faculty of Health Sciences Marien NGOUABI University Brazzaville Congo Clinical Psychology Research Division Marien NGOUABI University Brazzaville Congo Biomedical Analyses Center Makelekele Brazzaville Congo Laboratory of Numerical Analysis Computer Science and Applications Faculty of Sciences and Technology Marien NGOUABI University Brazzaville Congo

Background. The effects of physical exercises combined with a low-calorie diet on weight loss, body composition, lipoproteins profile, and physical fitness had been well described. However, Central Africa’s studies investigating these kinds of diets and exercise regimens are lacking. Objective. To investigate the effects of adding 14-weeks exercises to a hypocaloric diet on changes in body composition, lipoproteins concentrations, and physical capacities in obese Congolese women. Population and methods. In total, 34 obese women aged 30 - 39 years (mean age: 33.7 ± 2.4 years) assigned to 14-weeks training program and low energy ketogenic diet. Body composition was assessed using classic methods and impedancemetry. Fasting plasma glucose (FPG) and fasting serum insulin were assessing using enzymatic colorimetric and radioim-munoradiometric methods. HOmA-IR and lipoproteins concentrations were assessed using standardized laboratory methods. VO2peak was measured on a treadmill during a progressive exercise test. Speed, cadence and stride length were measured along the 10-m level walkway. muscular endurance was measured using the tests of sit-up and inflections-extensions of elbows. All the variables of the study were assessed at the beginning, in the 7-weeks, and in the 14-weeks of training methods. Results. Declines in body weight (16%), percent fat (12.1%), fat weight (26.4%), abdominal fat (34.2%), and waist circumference (10.4%) were found. A significant decrease in FPG (13%), fasting serum insulin (60.9%), HOmA-IR (64.7%), total cholesterol (12.2%), LDL-cholesterol (20.3%), triglycerides (92.8%), and VLDL-triglycerides (17.5%) was shown. In contrast, significant increase in HDL-cholesterol (27.13%) was found. The peak oxygen consumption VO2peak relative to body weight improved more in the 14-weeks training program (13.4%). Obese women exhibited higher values in the 14-weeks training program for speed gait (16.5%), cadence (9.1%), and stride length (15.7%) during no

关键词： Lipoproteins Body Composition Calorie Restriction Physical Exercise Obese Congolese Women

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Systematic management of twins to reduce pregnancy complications

Systematic management of twins to reduce pregnancy complicat...

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2019长三角围产医学学术会议暨浙江省围产医学学术大会

作者： Gao L Lv SP Zao XR Wu Y Liu Cm Hua ry Wang S Zhang Y Wang YL

OBJECTIVE: The purpose of this study was to describe the benefits of the systematic management of twin ***: A prospective cohort study of perinatal complications of twin pregnancy at International Peace maternity and Child Health Hospital(IPmCHH) in Shanghai, China, from 2013 to 2017. Since the mid of 2014, the specialist clinic for twin pregnancies was established and all twin pregnancies were enrolled in IPmCHH. The guidance included diet, physical activity, weight control, sleep, mentality and standardized medical support. Especialy,GDm-like diet and exercise management is the point for systematic management of *** research objects were the twin pregnancies delivered in 2015-2017. The twin pregnancies delivered in 2013-2014 were belonged to control group. Eligibility criteria included twin pregnancies delivered after 26 gestational weeks. Women with major fetal anomalies or stillbirth before labor were ***: In total, 1994 women who were twin pregnancies were recruited. 710 women in 2013-2014, and 1284 women in 2015-2017. It showed dramatic decline of prenatal weight gain in the group of Pre pregnancy BmI ≤ 29 Kg/m2(Pm(Pmia(Pmplicated with premature(Pm hemorrhage(Pmely low birth weight(ELBW) infants were significantly decreased in 2015-2017(Pm(2.7% vs 4.0%), and gestational diabetes mellitus(20.1% vs 19.4%).CONCLUSION: These findings highlighted the importance of systematic management,especialy, GDm-like diet and exercise management for twin pregnancy. Systematic management was helpful in reducing the perinatal complications of twin pregnancy. Regular physical activity during pregnancy did not increase the rate of premature of twins.

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