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Cognitive changes associated with ADT： a review of the literature

Asian journal of Andrology 2012年第2期14卷 232-238页

作者： Rhoda j jamadar m.ry j winters Pauline m maki Center for Cognitive medicine Department of Psychiatry university of Illinois at Chicago Chicago IL 60612 USA Department of Psychology University of Illinois at Chicago Chicago IL 60612 USA

The use of androgen deprivation therapy （ADT） has increased since the early 1990s after early detection efforts and greater use of the prostate-specific antigen （PSA） test. Although ADT is associated with favorable clinical outcomes, ADT has been associated with an increased risk for cardiovascular disease, increased serum cholesterol, triglycerides, insulin resistance, body mass index and fat body mass. Here we review findings from 11 clinical studies examining the effects of ADT on cognition as measured by standardized tests in cognitive domains such as verbal and spatial mem.ry. most of these studies have important limitations, including small sample sizes, suboptimal control groups and baseline group differences in confounding factors. Despite these limitations, the best designed studies, those comparing patients on ADT to healthy controls, generally suggest that spatial mem.ry might be especially sensitive to the effects of ADT. Critically, to date there is only one study involving random assignment of ADT versus close clinical observation. That study revealed a decrease in verbal mem.ry with ADT, but was limited in sample size and did not include a measure of spatial mem.ry. A recent observational study revealed no substantial evidence of cognitive impairment with ADT, even in the domain of verbal mem.ry. Like the randomizedstudy, however, this large observational study lacked a measure of spatial mem.ry. Overall, the studies with the best controls suggest a potential negative impact of ADT on spatial mem.ry, and perhaps verbal mem.ry, and a need for continued investigation of the impact of ADT on cognition, particularly in these two cognitive domains.

关键词： androgen deprivation therapy cognition prostate cancer

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Thermomechanical Processing and Superplasticity of AZ91 magnesium Alloy

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journal of materials Science & Technology 2004年第3期20卷 295-297页

作者： RongshiCHEN j.j.Blandin m.Suéry QudongWANG EnhouHAN StateKeyLabforCorrosionandProtection InstituteofMetalResearchChineseAcademyofSciencesShenyang110016China InstitutNationalPolytechniquedeGrenoble(INPG)GéniePhysiqueetmécaniquedesmatériaux(GPm2) UMRCNRS5010ENSPGBP4638402Saint-Martind'HéresCedexFrance SchoolofmaterialsScience&Engineering NationalResearchCenterofLightAlloyNetFormingEngineeringShanghaiJiaoTongUniversityShanghai200030China

The effect of extrusion on grain refinement has been studied in the AZ91 cast ingots. It is found that grain sizesmaller than 10μm can be obtained by the extrusion processing. Vickers hardness measurements were also carriedout to evaluate the effect of these processes on the room temperature mechanical properties. The experimentalresults of high temperature tensile tests revealed that the stress was inversely proportional to the square of the grainsize and that the activation energy for superplastic flow was higher than that for grain boundary diffusion.

关键词： magnesium alloy Thermo-mechanical treatment Superplasticity mechanical properties

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Influence of extrusion temperature on microstructure and mechanical properties of mg-4Y-4Sm-0.5Zr alloy

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Transactions of Nonferrous metals Society of China 2010年第7期20卷 1311-1315页

作者：李大全王渠东丁文江 j.j.BLANDIN m.SUéry National Engineering Research Center for Nonferrous metals Composites General Research Institute for Nonferrous Metals National Engineering Research Center of Light Alloys Net Forming State Key Laboratory of Metal Matrix CompositesSchool of Materials Science and EngineeringShanghai Jiao Tong University Universitéde Grenoble Grenoble INPScience et Ingénieriedes Matériaux et Procédés(SIMAP) CNRS UMR 5266UJFBP 4638402 Saint-Martin d'Héres CedexFrance

The solution-treated mg-4Y-4Sm-0.5Zr alloy was extruded at temperatures from 325℃ to 500℃.Dynamic recrystallization(DRX) completely occurs when the alloy is extruded at 350℃and *** grains of the extruded alloy are obviously refined by the occurrence of *** average grain size of the extruded alloy increases with increasing the extrusion temperature,leading to a slight decrease of the ultimate tensile strength(UTS) and the yield strength(YS) .On the contrary,the UTS and YS of the extruded and aged alloy increase with increasing the extrusion *** of UTS of 400 mPa,YS larger than 300 mPa and elongation(EL) of 7%are achieved after extrusion at 400℃ and ageing at 200℃ for 16 *** grain refinement and precipitation are efficient strengthening mechanisms for the mg-4Y-4Sm-0.5Zr alloy.

关键词： mg-Y-Sm-Zr alloy extrusion heat treatment ageing mechanical properties

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太极拳对于老年癌症幸存者的作用:减缓瘤症治疗引起的残疾、跌倒、心脏病的加速发展(英文)

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journal of Sport and Health Science 2014年第1期3卷 52-57+1+65页

作者： Kerri m.winters-Stone School of Nursing and Knight Cancer Institute Oregon Health & Science University

美国目前有超过1 370万癌症幸存者,预计这一数字将会在未来10年增加31%,医疗保健体系中将新增400万癌症幸存者。癌症在很大程度上与衰老相关,人口衰老会急剧增加老年癌症幸存者比例,其中很多是长期幸存者(确诊后5年)。本文综述了运动可... 详细信息

美国目前有超过1 370万癌症幸存者,预计这一数字将会在未来10年增加31%,医疗保健体系中将新增400万癌症幸存者。癌症在很大程度上与衰老相关,人口衰老会急剧增加老年癌症幸存者比例,其中很多是长期幸存者(确诊后5年)。本文综述了运动可能改善残疾、跌倒、心脏病的作用,这3种健康问题对老年癌症幸存者和医疗保健体系尤为重要,因为这些与衰老相关的问题会因为癌症治疗而加剧。虽然有多种运动形式及其改编版本,太极拳可能是减缓衰老、解决癌症相关问题的最佳选择。对非癌症患者的老年人的研究显示,太极拳能引起骨骼肌和有氧代谢适应,而且由于耗能低、运动模式缓慢而易于让老年人完成。由于癌症幸存者大多年老、不活跃,经常因为治疗的副作用而行动受限,他们需要安全实用且有效的运动形式。当前缺少已发表的研究太极拳减缓癌症治疗相关的骨骼肌和心血管副作用的对照实验,可见,在探索应用这种非西方运动形式改善老年癌症幸存者的长期结果方面存在相当多的研究机遇。

关键词：衰老癌症幸存者化学疗法运动肿瘤体力活动生理机能太极拳

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Extracting structural motifs from pair distribution function data of nanostructures using explainable machine learning

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npj Computational materials 2022年第1期8卷 2053-2063页

作者： Andy S.Anker Emil T.S.Kjær mikkel juelsholt Troels Lindahl Christiansen Susanne Linn Skjærvø mads ry Vogel jørgensen Innokenty Kantor Daniel Risskov Sørensen Simon j.L.Billinge Raghavendra Selvan Kirsten m.Ø.jensen Department of Chemistry and Nano-Science Center University of Copenhagen2100CopenhagenDenmark Department of materials University of OxfordParks RoadOxfordUK Department of Chemistry&iNANO Aarhus University8000AarhusDenmark mAX IV Laboratory Lund University22484LundSweden Department of Physics Technical University of Denmark2880LyngbyDenmark Department of Applied Physics and Applied mathematics Columbia UniversityNew YorkNY10027USA Condensed matter Physics and materials Science Department Brookhaven National LaboratoryUptonNY11973USA Department of Computer Science University of Copenhagen2100CopenhagenDenmark Department of Neuroscience University of Copenhagen2200CopenhagenDenmark

Characterization of material structure with X-ray or neutron scattering using *** Distribution Function(PDF)analysis most often rely on refining a structure model against an experimental ***,identifying a suitable model is often a ***,automated approaches have made it possible to test thousands of models for each dataset,but these methods are computationally expensive and analysing the output,*** structural information from the resulting fits in a meaningful way,is *** machine Learning based motif Extractor(mL-motEx)trains an mL algorithm on thousands of fits,and uses SHAP(SHapley Additive exPlanation)values to identify which model features are important for the fit *** use the method for 4 different chemical systems,including disordered nanomaterials and ***-motEx opens for a type of modelling where each feature in a model is assigned an importance value for the fit quality based on explainable mL.

关键词： explain structural meaningful

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基于影像组学、视觉和直方图评估证实冠状动脉CT血管成像上动脉粥样硬化病变的体外研究

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国际医学放射学杂志 2019年第6期 735-736页

作者： m.Kolossváry j.Karády Y.Kikuchi A.Ivanov C.L.Schlett m.T.Lu 许棚棚 mTA-SE Cardiovascular Imaging Research Group Heart and Vascular Center Semmelweis University

摘要目的以组织学检查确定的晚期动脉粥样硬化病变为诊断标准,在体外冠状动脉CT血管成像基础上,比较基于影像组学的机器学习方法与基于视觉和直方图评估方法

关键词：冠状动脉机器学习模型动脉粥样硬化病变 CT 影像组学体外研究直方图

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Decision support system for the mobile volcano fast response system

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International journal of Digital Earth 2010年第3期3卷 280-291页

作者： S.Bernsdorf R.Barsch m.Beyreuther K.Zakšek m.Hort j.Wassermann CentauronGeosoftware&Consulting JenaGermany Department of Earth and Environmental Sciences Ludwig-Maximilians-UniversityMunichGermany Institute of Geophysics University of HamburgHamburgGermany

A mobile volcano fast response system(VFRS)that can be used for volcano monitoring in case of volcanic unrest anywhere in the world is currently under development in *** main goal of the project called Exupéry is to provide the communication technology for stations in the field and an expert system that collects all data from various sources,assembles them in a database,and allows users to assess the data through one common web GIS *** system also includes an integrated automatic alert level including the alert level estimation in order to characterize the activity state of the *** web GIS interface serves as a decision support system to assist scientists and local authorities in deciding how to react in the case of volcanic unrest.

关键词： volcanic unrest decision support system web GIS interface automatic alert level Exupéry VFRS

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开普菲尔底辟、布莱克海脊底辟和布莱克海脊沉积物应力史和土工性质研究

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海洋地质 2009年第2期25卷 37-46页

作者：刘广虎（译）王金莲（校） W．j．winters

对ODP164航次获取的沉积物进行了土工性质的测试：（1）在船上对采自开普菲尔底辟、布莱克海脊底辟和布莱克海脊的沉积物进行了常规强度比测试（2）在实验室对采自995A孔（位于布莱克海脊）的沉积物进行了阿特堡界限、小型十字板剪切强... 详细信息

对ODP164航次获取的沉积物进行了土工性质的测试：（1）在船上对采自开普菲尔底辟、布莱克海脊底辟和布莱克海脊的沉积物进行了常规强度比测试（2）在实验室对采自995A孔（位于布莱克海脊）的沉积物进行了阿特堡界限、小型十字板剪切强度、微型贯入强度以及等应变速率固结试验等项目的测试。研究区域具有沉积速率很高并赋存水合物的特点，此次研究的主要目的是为了解该区域沉积物应力史。根据结果显示，总的来说，布莱克海脊的沉积物除了近表层以外其他层位都表现为明显的欠固结状态。与周围站位相比，位于开普菲尔底辟上的993A孔通过侵蚀或块体坡移作用至少缺失了10m厚的海底表土。

关键词：沉积物海脊底辟性质土工应力菲等应变速率

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Prediction of spatial heterogeneity in nutrient-limited sub-tropical maize yield:Implications for precision management in the eastern Indo-Gangetic Plains

Artificial Intelligence in Agriculture

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Artificial Intelligence in Agriculture 2024年第3期13卷 100-116页

作者： Zia Uddin Ahmed Timothy j.Krupnik jagadish Timsinab Saiful Islam Khaled Hossain A.S.m.Alanuzzaman Kurishi Shah-Al Emran m.Harun-Ar-Rashid Andrew j.mcDonald mahesh K.Gathala University at Buffalo New YorkUSA International maize and Wheat Improvement Center Dhaka 1213Bangladesh Global Ever Greening Alliance 1 Vision DriveBurwood EastMelbourneAustralia Department of Crop Sciences University of Illinois at Urbana-ChampaignUrbanaILUSA SAARC Agriculture Centre DhakaBangladesh Cornell University School of Integrative Plant Science Soil and Crop Sciences SectionNYUSA

Knowledge of the factors influencing nutrient-limited subtropical maize yield and subsequent prediction is crucial for effective nutrientmanagement,maximizing profitability,ensuring food security,and promoting environmental *** data fromnutrient omission plot trials(NOPTs)conducted in 324 farmers'fields across ten agroecological zones(AEZs)in the Eastern Indo-Gangetic Plains(EIGP)of Bangladesh to explain maize yield variability and identify variables controlling nutrient-limited *** additive main effect and multiplicative interaction(AmmI)model was used to explain maize yield variability with nutrient *** machine learning(mL)algorithms in automatic machine learning(AutomL)frameworks were subsequently used to predict attainable yield relative nutrient-limited yield(ry)and to rank variables that control *** stack-ensemble model was identified as the best-performing model for predicting rys of N,P,and *** contrast,deep learning outperformed all base learners for predicting *** best model's square errors(RmSEs)were 0.122,0.105,0.123,and 0.104 for ry_(N),ry_(P),ry_(K),and ry_(Zn),*** permutation-based feature importance technique identified soil pH as the most critical variable controlling ry_(N)and ry_(P).The ry_(K)showed lower in the eastern longitudinal *** N and Zn were associated with *** predicted median ry of N,P,K,and Zn,representing average soil fertility,was 0.51,0.84,0.87,and 0.97,accounting for 44,54,54,and 48%upland dry season crop area of Bangladesh,*** are needed to update databases cataloging variability in land type inundation classes,soil characteristics,and INS and combine them with farmers'crop management information to develop more precise nutrient guidelines for maize in the EIGP.

关键词： Relative yield Additive main effect and multiplicative interaction (AmmI) Quantile regression automL Stack-ensemble Partial dependency plots

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多层CT Willis环成像:Willis环变异与颈动脉病变及脑缺血的相关性

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国际医学放射学杂志 2019年第2期42卷 242-243页

作者： A.Varga G.D.Leo P.V.Banga C.C.Novák m.Kolossváry P.m.Horvat 郑育聪(译) 陈秀玉(校) Department of Diagnostic Radiology Heart and Vascular CenterSemmelweis University18 Határor streetBudapest 1122Hungary 不详

目的评估颈动脉内膜剥脱术病人Willis环(CoW)的变异率,并探讨变异与对照组及CT诊断的脑缺血的相关性。方法本研究经机构伦理委员会批准,回顾性分析544例颈动脉内膜剥离术病人[男331例,平均年龄(69±8)岁]和196例对照组[男117例。

关键词：脑缺血变异率 Willis CT Willis 相关性

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