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CSEE Journal of Power and Energy Systems 2025年第1期11卷 352-364页

作者： Abdelfattah A.Eladl magda I.El-Afifi magdi m.El-Saadawi Bishoy E.Sedhom Electrical Engineering Department Faculty of EngineeringMansoura UniversityEl-MansouraEgypt

This paper proposes an IoT-Fog-Cloud distributed consensus algorithm for solving the energy hub(EH)dispatch problem with packet-dropping communication links and some of EH elements'*** generating and consumption unit in this algorithm is required to estimate total power generated,total load,and power *** node coordination is accomplished using a distributed *** a distributed approach wins in work sharing,enduring a single link failure,effective decision-making,quickest convergence,and autonomy for global power *** method works with all grid types in connected and islanded *** total operation cost and emissions while meeting total demand and system constraints are the most crucial contributions of this *** case studies are applied to explain performance and effectiveness of the proposed algorithm with different packet loss *** uncertainty,sensitivity of the system was *** show mismatch between generated and consumed power is improved by 100%in the electricity grid,99.94%in heating grid,and 99.91%in gas ***,total operating cost,total emissions,and emissions cost decreased by 8.6%,13.48%,and 18.73%,respectively.

关键词： Consensus algorithm CO_(2)emissions energy hubs multi-energy systems packet drops.

Using Transgenic Entomopathogenic Fungi to Prevent Dengue Fever: Current Status, Challenges and Perspectives

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Advances in Entomology 2025年第1期13卷 48-60页

作者： Etienne m. Bilgo Houeffa Adeline Tatiana Dokpomiwa Abdoulaye Diabate Biomedical and Public Health Department Institute of Research in Health Sciences (IRSS) Western Regional Directorate Bobo-Dioulasso Burkina Faso muraz Center National Institute of Public Health (INSP) Bobo Dioulasso Burkina Faso Rural Development Institute (IDR) Nazi Boni University (UNB) Bobo Dioulasso Burkina Faso

Over the last few decades, dengue fever epidemics have increased in frequency and intensity worldwide, making it a major global concern for public health. Its prevention, which is essentially vector-based control, is already being compromised by reports of resistance of the main vector Aedes aegypti to insecticides. To tackle the rapid increase in insecticide resistance and outbreaks, the biological vector control is a promising approach. One of the strategies of this approach is the use of entomopathogenic fungi because of their great efficacy and their eco-friendly aspects. However, some aspects of their use, such as the low efficiency, the high cost of production and the sensitivity to various adverse conditions, need to be addressed for their successful large-scale application. Therefore, innovative technologies based on strains of transgenic fungi with improved biocontrol potentials by genetic engineering are actively pursued. Although these modified mycoinsecticides are acclaimed for their better effectiveness against target insects, the main concern remains their potential adverse effects on the environment and human health. The present review is dedicated to giving an update on recent developments in transgenic entomopathogenic fungi (TEF) for Aedes mosquito control. Future perspectives are also proposed to address the safety concerns related to the release of transgenic entomopathogenic fungi into the environment.

关键词： Transgenic Entomopathogenic Fungi Dengue Control

ClpB chaperone as a promising target for antimicrobial therapy: A narrative review

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Asian Pacific Journal of Tropical Biomedicine 2025年第1期15卷 1-10,I0001-I0007页

作者： Sachini J.Udari Sayoka Shamodhi Rumesh m.Nelumdeniya Udayana Ranatunga Nimesha N.Senadeera Chathuranga B.Ranaweera Department of medical Laboratory Sciences Faculty of Allied Health SciencesGeneral Sir John Kotelawala Defence UniversityWerahera10718Sri Lanka Department of Pharmacy Faculty of Allied Health SciencesGeneral Sir John Kotelawala Defence UniversityWerahera10718Sri Lanka Department of Chemistry Faculty of ScienceUniversity of PeradeniyaPeradeniya20400Sri Lanka Department of Zoology and Environment Sciences Faculty of ScienceUniversity of ColomboColombo 0300300Sri Lanka

The Clp/Hsp100 family,part of the ATPase associated with various cellular activities(AAA+)superfamily,includes caseinolytic peptidase B(ClpB),a highly conserved protein found in bacteria,fungi,protozoa,and ***,ClpB is present in all ESKAPE pathogens:Enterococcus faecium,Staphylococcus aureus,Klebsiella pneumoniae,Acinetobacter baumannii,Pseudomonas aeruginosa,and Enterobacter *** plays a crucial role in reactivating and disaggregating proteins,enabling pathogens to survive under host-induced stress and conferring thermotolerance to bacterial *** caused by ESKAPE pathogens are particularly challenging due to their resistance to broad-spectrum antibiotics and biofilm formation,posing a significant global health threat as they are often multidrug-resistant,extensively drug-resistant,and *** its absence in human cells and its essential role in bacterial survival under stress,ClpB is a promising target for antimicrobial *** Hsp100 family proteins could lead to the development of novel antifungal and antiprotozoal *** review explores the function of ClpB in the survival of ESKAPE pathogens and the protozoan Plasmodium *** research findings were compiled using academic databases,and data analysis was performed using Clustal Omega multiple Sequence Alignment and Boxshade tools.

关键词： molecular chaperone ClpB ESKAPE pathogens Thermotolerance Heat shock proteins Plasmodium falciparum

Implementation of a double trigger condition system based on charge comparison and TOF measurement for the NEDA detector array

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Nuclear Science and Techniques 2025年第2期36卷 40-48页

作者： J.m.Deltoro A.Goasduff F.J.Egea V.González A.Gadea R.m.Pérez-Vidal I.Lazarus m.Kogimtzis L.mcNicholl m.Palacz G.Jaworski J.J.Valiente-Dobón J.Nyberg S.Casans A.E.Navarro-Antón E.Sanchis A.Boujrad E.Clément T.Hüyük R.Illicachi O.Stezowski V.modamio Department of Electronic Engineering University of ValenciaBurjassotValenciaSpain Istituto Nazionale di Fisica Nucleare Laboratori Nazionali di LegnaroLaboratori Nazionali di LegnaroLegnaroPadovaItaly Instituto de Física Corpuscular CSIC-Universidad de ValenciaCSIC-Universidad de Valencia46980 PaternaValenciaSpain Science and Technology Facilities Council DaresburyUK Heavy Ion Laboratory University of Warsaw02-093 WarsawPoland Department of Physics and Astronomy Uppsala UniversityUppsalaSweden Grand Accélérateur National d’Ions Lourds(GANIL) CEA/DRF-CNRS/IN2P3CEA/DRF-CNRS/IN2P3CaenFrance Universitéde Lyon UniversitéLyon-1CNRS/IN2P3UMR5822IP2IIP2I4 Rue Enrico Fermi69622 Villeurbanne CedexFrance Department of Physics University of Oslo0316 OsloNorway

The NEutron Detector Array(NEDA)is designed to be coupled to gamma-ray spectrometers to enhance the sensitivity of the setup by enabling reaction channel selection through counting of the evaporated *** article presents the implementation of a double trigger condition system for NEDA,which improves the acquisition of neutrons and reduces the number of gamma rays *** independent triggers are generated in the double trigger condition system:one based on charge comparison(CC)and the other on time-of-flight(TOF).These triggers can be combined using OR and AND logic,offering four distinct trigger *** developed firmware is added to the previous one in the Virtex 6 field programmable gate array(FPGA)present in the system,which also includes signal processing,baseline correction,and various trigger logic *** performance of the trigger system is evaluated using data from the E703 experiment performed at *** four trigger modes are applied to the same data,and a subsequent offline analysis is *** is shown that most of the detected neutrons are preserved with the AND mode,and the total number of gamma rays is significantly *** with the CC trigger mode,the OR trigger mode allows increasing the selection of *** addition,it is demonstrated that if the OR mode is selected,the online CC trigger threshold can be raised without losing neutrons.

关键词： Neutron detector Neutron-gamma discrimination Pulse shape analysis Time-of-flight Charge comparison

基于特征提取和Stacking集成学习的软件缺陷预测

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计算机应用与软件 2025年第1期42卷 25-29,48页

作者：崔梦天吴克奇 mariani m S 西南民族大学计算机科学与工程学院四川成都610041 苏黎世大学信息系瑞士苏黎世8050

针对缺陷数据的相关性较高以及单一的分类算法存在泛化性不高的问题,提出一种软件缺陷预测模型KSSDP(KPCA Stacking Software Defect Prediction)。采用核主成分分析(KPCA)对缺陷数据集进行特征提取,使用混合采样SmOTEENN方法解决缺陷... 详细信息

针对缺陷数据的相关性较高以及单一的分类算法存在泛化性不高的问题,提出一种软件缺陷预测模型KSSDP(KPCA Stacking Software Defect Prediction)。采用核主成分分析(KPCA)对缺陷数据集进行特征提取,使用混合采样SmOTEENN方法解决缺陷数据集的类不平衡问题,使用K-means算法对缺陷数据集进行聚类以剔除异常值,使用Stacking集成学习构建KSSDP集成预测模型并进行仿真实验,结果表明该模型比基模型、主流集成模型和深度学习模型的性能更好。

关键词：核主成分分析特征提取 KSSDP模型集成学习软件缺陷预测

Extracellular vesicles:multiple signaling capabilities and translation into promising therapeutic targets to promote neuronal plasticity

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Neural Regeneration Research 2025年第12期20卷 3521-3522页

作者： Dirk m.Hermann Bernd Giebel Department of Neurology University Hospital EssenEssenGermany Institute for Transfusion medicine University Hospital EssenEssenGermany

Extracellular vesicles(EVs)are cell-derived,lipid membrane-enclosed vesicles carrying a broad spectrum of biologically active molecules(including proteins,RNAs,and bioactive lipids)which play important roles in intercellular *** crucially control neuronal energy metabolism under physiological conditions,constrain oxidative stress a nd brain inflammatory responses,and promote neuronal survival and plasticity upon brain damage.

关键词： plasticity oxidative spectrum

modeling net-charge fluctuations in heavy-ion collisions at the LHC

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Chinese Physics C 2025年第1期49卷 281-289页

作者： G.O.Ambaryan A.S.Chernyshov G.Kh.Eyyubova V.L.Korotkikh I.P.Lokhtin S.V.Petrushanko A.m.Snigirev E.E.Zabrodin Physics Department Lomonosov Moscow State UniversityRU-119991 MoscowRussia Skobeltsyn Institute of Nuclear Physics Lomonosov Moscow State UniversityRU-119991 MoscowRussia Bogoliubov Laboratory of Theoretical Physics Joint Institute for Nuclear ResearchRU-141980 DubnaRussia Department of Physics University of OsloN-0316 OsloNorway

Analysis of Pb+Pb data for net-charge fluctuations at LHC energies using the HYDJET++model is *** strongly intensive quantities D and Σ were used to remove the effects related to system volume *** employed two versions of HYDJET++for the *** first one is the standard or default version,whereas the second one is a modification that takes into account explicit event-by-event conservation of the electric net-charge of produced *** inclusion of the canonical net-charge conservation in the model allows for better description of the experimental data obtained by the ALICE and CmS Collaborations.A comparison with calculations from other models is also presented.

关键词： relativistic heavy-ion collisions net-charge fluctuations strongly intensive variables canonical charge conservation

Atmospheric CO_(2) Removal Efficiency through Enhanced Silicate Weathering in Croplands:A Review with Emphasis on the Contribution of Fungi

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Journal of Earth Science 2025年第1期36卷 197-211页

作者： Zi-Bo Li Gaojun Li Jonathan m.Adams Dong-Xing Guan Liang Zhao Rongjun Bian Qing Hu Xiancai Lu Junfeng Ji Jun Chen State Key Laboratory of Palaeobiology and Stratigraphy Nanjing Institute of Geology and PalaeontologyChinese Academy of SciencesNanjing 210008China Key Laboratory of Surficial Geochemistry Ministry of EducationSchool of Earth Sciences and Engineering and Frontiers Science Center for Critical Earth Material CyclingNanjing UniversityNanjing 210023China School of Geography and Ocean Science Nanjing UniversityNanjing 210023China Institute of Soil and Water Resources and Environmental Science College of Environmental and Resource SciencesZhejiang UniversityHangzhou 310058China Institute of Resource Ecosystem and Environment of AgricultureNanjing Agricultural UniversityNanjing 210095China Xiong'an Institute of Innovation Chinese Academy of SciencesXiong'an 071700China

Enhanced silicate weathering(ESW)is a geoengineering method aimed at accelerating carbon dioxide(CO_(2))removal(CDR)from atmosphere by increasing the weathering flux of silicate rocks and *** has emerged as a promising strategy for *** studies underscore ESW’s substantial potential for CDR and its diverse benefits for crops when applied to ***,the well-known significant discrepancies in silicate weathering rates between laboratory and field conditions introduce uncertainty in CDR through *** compiling data from recent literature,we calculated and compared CDR efficiency(t CO_(2)t^(-1)_(silicate)ha^(-1)y^(-1))observed in mesocosm experiments and field *** findings indicate that CDR efficiencies in field trials are comparable to or exceeding that observed in mesocosm experiments by 1-3 orders of magnitude,particularly evident with wollastonite *** hierarchy of CDR efficiency among silicates suitable for ESW is ranked as follows:olivine≥wollastonite>basalt>albite≥*** suggest the potential role of biota,especially fungi,in contributing to higher CDR efficiencies observed in field trials compared to mesocosm *** further emphasize introducing fungi known for their effectiveness in silicate weathering could potentially enhance CDR efficiency through ESW in *** before implementing fungal-facilitated ESW,three key questions need addressing:(i)How does the community of introduced fungi evolve over time?(ii)What is the long-term trajectory of CDR efficiency following fungal introduction?and(iii)Could fungal introduction lead to organic matter oxidation,resulting in elevated CO_(2)emissions?These investigations are crucial for optimizing the efficiency and sustainability of fungal-facilitated ESW strategy.

关键词： enhanced weathering carbon dioxide removal efficiency fungi weathering rate altered surface layers

Optimizing non-invasive vagus nerve stimulation for treatment in stroke

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Neural Regeneration Research 2025年第12期20卷 3388-3399页

作者： Sheharyar S.Baig Samantha Dorney mudasar Aziz Simon m.Bell Ali N.Ali Li Su Jessica N.Redgrave Arshad majid Sheffield Institute for Translational Neuroscience Department of NeuroscienceUniversity of SheffieldSheffieldUK Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust DoncasterUK

Stroke remains a leading cause of long-term disability *** is an unmet need for neuromodulatory therapies that can mitigate against neurovascular injury and potentially promote neurological *** vagus nerve stimulation has been demonstrated to show potential therapeutic effects in both acute and chronic ***,previously published research has only investigated a narrow range of stimulation settings and *** this review,we detail the ongoing studies of transcutaneous vagus nerve stimulation in stroke through systematic searches of registered clinical *** summarize the upcoming clinical trials of transcutaneous vagus nerve stimulation in stroke,highlighting their indications,parameter settings,scope,and *** further explore the challenges and barriers associated with the implementation of transcutaneous vagus nerve stimulation in acute stroke and stroke rehabilitation,focusing on critical aspects such as stimulation settings,target groups,biomarkers,and integration with rehabilitation interventions.

关键词： neuromodulation neuroplasticity rehabilitation stroke vagal nerve stimulation vagus nerve stimulation

Prevalence of RUNX1 gene alterations in de novo adult acute myeloid leukemia

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World Journal of Experimental medicine 2025年第1期15卷 65-79页

作者： Hoda m Abd El-Ghany mona S El Ashry mona S Abdellateif Ahmed Rabea Nada Sultan Omnia Y Abd El Dayem Department of Clinical Pathology Faculty of MedicineCairo UniversityCairo 11976Al QāhirahEgypt Department of Clinical Pathology National Cancer InstituteCairo UniversityCairo 11976Al QāhirahEgypt Department of Cancer Biology National Cancer InstituteCairo UniversityCairo 11976Al QāhirahEgypt Department of medical Oncology National Cancer InstituteCairo UniversityCairo 11976Al QāhirahEgypt

BACKGROUND Acute myeloid leukemia(AmL)is a complicated disease with uncontrolled hematopoietic precursor proliferation induced by various genetic ***-related transcription factor-1(RUNX1)is commonly disrupted by chromosomal translocations in hematological *** To characterize RUNX1 gene rearrangements and copy number variations in newly diagnosed adult AmL patients,with an emphasis on the impact of clinical and laboratory features on the *** Fluorescence in situ hybridization was used to test RUNX1 gene alterations in 77 newly diagnosed adult AmL ***1,FLT3/ITD,FLT3/TKD,and KIT mutations were tested by *** clinical and laboratory findings were studied in relation to RUNX1 *** RUNX1 abnormalities were detected by fluorescence in situ hybridization in 41.6%of patients:20.8%had translocations,22.1%had amplification,and 5.2%had *** prevailed in AmL-m2(P=0.019)with a positive expression of myeloperoxidase(P=0.031),whereas deletions dominated in m4 and m5 subtypes(P=0.008)with a positive association with CD64 expression(P=0.05).The modal chromosomal number was higher in cases having amplifications(P=0.007)and lower in those with deletions(P=0.008).RUNX1 abnormalities were associated with complex karyotypes(Pmutually exclusive of NPm1 *** 44 months of follow-up,RUNX1 abnormalities affected neither patients’response to treatment nor overall *** RUNX1 abnormalities were mutually exclusive of NPm1 ***1 abnormalities affected neither patients’response to treatment nor overall survival.

关键词： Acute myeloid leukemia Deletion Disease-free survival Fluorescence in-situ hybridization Karyotyping RUNX1