检索结果-南通市图书馆

Optimizing non-invasive vagus nerve stimulation for treatment in stroke

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第12期20卷 3388-3399页

作者： Sheharyar S.Baig Samantha Dorney mudasar Aziz Simon m.Bell Ali N.Ali Li Su Jessica N.Redgrave Arshad majid Sheffield Institute for Translational Neuroscience Department of NeuroscienceUniversity of SheffieldSheffieldUK Doncaster and Bassetlaw Teaching Hospitals NHS Foundation Trust DoncasterUK

Stroke remains a leading cause of long-term disability *** is an unmet need for neuromodulatory therapies that can mitigate against neurovascular injury and potentially promote neurological *** vagus nerve stimulation has been demonstrated to show potential therapeutic effects in both acute and chronic ***,previously published research has only investigated a narrow range of stimulation settings and *** this review,we detail the ongoing studies of transcutaneous vagus nerve stimulation in stroke through systematic searches of registered clinical *** summarize the upcoming clinical trials of transcutaneous vagus nerve stimulation in stroke,highlighting their indications,parameter settings,scope,and *** further explore the challenges and barriers associated with the implementation of transcutaneous vagus nerve stimulation in acute stroke and stroke rehabilitation,focusing on critical aspects such as stimulation settings,target groups,biomarkers,and integration with rehabilitation interventions.

关键词： neuromodulation neuroplasticity rehabilitation stroke vagal nerve stimulation vagus nerve stimulation

X-linked Toll-like receptor 7 polymorphism associated with susceptibility to Chikungunya Fever

在线全文

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical medicine 2019年第3期12卷 137-141页

作者： Daniela m.Rauseo mercedes Fernández-mestre Laboratorio de Fisiopatología Centro de Medicina ExperimentalIVIC

Objective: To investigate the association between TLR3 and TLR7 polymorphisms with susceptibility and clinical manifestations of Chikungunya ***: A total of 177 individuals were studied: 73 patients with a confirmed diagnosis for Chikungunya virus and 104 non-infected individuals. Polymorphisms were determined by Polymerase Chain Reaction-Restriction Fragment Length Polymorphism(PCR-RFLP).Results: Our analysis showed an increased CC genotype frequency of the TLR7 rs3853839 polymorphism in male patients compared to control(29% versus 2%,respectively; OR=20.69; 95% CI=2.55-167.36; Pmore,arthritis(acute and chronic) was frequently found in CC male patients. On the contrary,65% of CG carriers were no-infected males(29% versus 65%,respectively; OR=0.23,95% CI=0.48-3.04; P=0.002). Finally,we observed a higher frequency of lymphopenia in CG male patients(CG=666.86±233.77,GG=1,314.27±752.29 cells/mm3,P=0.047). Conclusions: Our results suggest the TLR7 rs3853839 polymorphism is associated with lymphopenia and increased susceptibility to Chikungunya Fever in males.

关键词： Chikungunya Fever Toll-like-receptors Single-nucleotide polymorphisms Disease susceptibility

Pods Filling in Natural Pollination of 10 Spontaneous Cocoa Trees from French Guiana

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Agricultural Sciences 2025年第1期16卷 193-205页

作者： Inago Caudou Trebissou Gnion mathias Tahi Kacou Antoine Alban m’bo Cacao Breeding Laboratory National Center for Agronomic Research (CNRA) Research Station of Divo Divo Cte dIvoire African Center of Excellence on Climate Change Biodiversity and Sustainable Agriculture (CEA-CCBAD/WASCAL) Flix Houphout-Boigny University (UFHB) Abidjan Cte dIvoire

The study focuses on the filling of pods from ten cacao clones originating from French Guiana in Côte d’Ivoire. Two reference clones (IFC5 and NA32) were used as controls. The parameters studied include the number of ovules per ovary, the average number of beans per pod, the fresh bean weight, and the pod index. The aim was to evaluate the genetic variability and agronomic performance of these clones under natural pollination conditions. The results show significant genetic variability between the clones for all traits studied. The IFC5 clone, known for its excellent pod filling, exhibited the highest apparent fertility (0.91), while the GU183/A clone had the lowest filling (0.47). Three types of distributions of the number of beans per pod were identified: a right-skewed unimodal distribution, characteristic of well-filled clones;a left-skewed unimodal distribution, associated with poorly filled clones;and an intermediate bimodal distribution. These differences could be related to pollination compatibility and the availability of compatible pollen. Regarding the fresh bean weight and pod index, the GU183/A clone stood out with the heaviest beans (3.27 g) but had a high pod index (49.58), indicating relatively low productivity. None of the Guyanese clones achieved the filling level of the IFC5 clone, although some surpassed the NA32 control. This study highlights the importance of apparent fertility and the number of beans per pod as essential criteria for cacao genetic improvement programs. The authors recommend extending research to a larger number of Guyanese clones and exploring complementary traits, such as the influence of pollination type and intergroup compatibility.

关键词： Theobroma cacao Phytophthora Pod Index Apparent Fertility

Hydrodeoxygenation of vegetable oil in batch reactor:Experimental considerations

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2020年第6期28卷 1670-1683页

作者： Alexis K.Noriega Alexis Tirado Cecilia méndez Gustavo marroquín Jorge Ancheyta Instituto Politécnico Nacional Centro de Investigación en Ciencia Aplicada y Tecnología Avanzada Unidad LegariaLegaria 694Col.Irrigación 11500Mexico Instituto mexicano del Petróleo Eje Central Lázaro Cárdenas Norte 152San Bartolo Atepehuacan 07730Mexico

The generation of reliable experimental data in any experimental scale requires proper procedures not only for the reaction step but also for the feed preparation,separation,and characterization of products as well as calculations of conversion and product *** reactor is the most used experimental setup for carrying out exploratory studies for catalyst screening and *** work is focused on describing and discussing a step-by-step methodology for conducting experiments for catalytic hydrotreating of vegetable oils in batch *** proposed methodology considers literature and own experiences on advantages and disadvantages of different feed types,catalysts,experimental setup and procedures,effect of reaction parameters,separation and characterization of products,and calculations.

关键词： Vegetable oils Hydrotreating Batch reactor

Heart failure in the elderly

在线全文

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2021年第3期18卷 219-232页

作者： Pablo Díez-Villanueva César Jiménez-méndez Fernando Alfonso Cardiology Department Hospital Universitario La PrincesaUniversidad Autónoma de MadridCIBER-CVMadridSpain

Heart failure(HF)is a clinical syndrome caused by structural and/or functional cardiac abnormalities,resulting in a reduced cardiac output and/or elevated intracardiac filling pressures at rest or during *** is a major public health problem with high prevalence and incidence,involving both high morbidity and mortality,but also high economic *** incidence of HF progressively increases with age,reaching around 20%among people over 75 years ***,HF represents the leading cause of hospitalization in patients older than 65 years in Western ***,some authors even consider HF a geriatric syndrome,entailing worse prognosis and high residual disability,and often associating some complex comorbidities,common in older population,that may further complicate the course of the *** the other hand,however,clinical course and prognosis may be often difficult to *** this article,main pathophysiological issues related to the aging heart are addressed,together with key aspects related to both diagnosis and prognosis in elderly patients with ***,main geriatric conditions,common in the elderly population,are reviewed,highlighting the importance of a comprehensive and multidisciplinary approach.

关键词： diagnosis elevated mortality

Experimental and numerical study of fence effects on dust emission into atmosphere from open storage piles

在线全文

学校读者我要写书评

暂无评论

Journal of Central South University 2011年第2期18卷 411-419页

作者： S.TORNO J.TORA-O m mENéndez m.GENT I.áLVAREZ mining and Civil Works Research Group Oviedo University School of mines Oviedo University

The results obtained from the research on the behaviour of fences (solid and porous) in the protection against particulated material emission to the atmosphere from open storage piles,are presented. This research was carried out through computational fluid dynamics (CFD) simulation by software Ansys CFX-10.0 in 3D,with K-epsilon being considered in the turbulence model. The efficiency of the use of porous fences as a protection against the wind flow,which interacts with an open storage pile,is shown. The use of these fences (when porosity is ε=30%) allows the reduction of wind flow velocity which interacts with the pile in comparison with the case of no use of fences (when porosity is 100%). In addition,the use of porous fences makes the velocity vortex,which is formed between the solid fence (ε=0%) and the pile,disappear,reducing the particle emission to the atmosphere by 78%.

关键词： open storage pile air pollution particle emission wind erosion porous fence computational fluid dynamics

在线全文

学校读者我要写书评

暂无评论

经验的认知私人性

世界哲学 2025年第02期 126-139页

作者： P.m.S.哈克张学广徐皓乙西北大学哲学学院外国哲学研究中心

经验的认知私人性学说认为，只有我真的知道我拥有一种既定的经验，其他人最多只能猜测，但无法真的知道我拥有的经验，或者不能像我一样确定地知道这一点。这一学说是笛卡尔和英国古典经验主义以来占主导地位的心灵理论，并为当代神经... 详细信息

经验的认知私人性学说认为，只有我真的知道我拥有一种既定的经验，其他人最多只能猜测，但无法真的知道我拥有的经验，或者不能像我一样确定地知道这一点。这一学说是笛卡尔和英国古典经验主义以来占主导地位的心灵理论，并为当代神经科学和心理学所加持。但是，该学说建立在对“内省”“意识”“察觉”“知道”等概念误解的基础上。维特根斯坦通过语法分析成功地表明，“我知道我疼痛”这类句子与“我知道他疼痛”和“他知道我疼痛”并不属于同一种语言游戏，第一人称现在时话语的特权地位不应该在特权通道的意义上理解。

关键词：认知私人性内省意识知道语言游戏

Solution‑Processed Thin Film Transparent Photovoltaics:Present Challenges and Future Development

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nano-micro Letters 2025年第2期17卷 566-600页

作者： Tianle Liu munerah m.S.Almutairi Jie ma Aisling Stewart Zhaohui Xing mengxia Liu Bo Hou Yuljae Cho Um-SJTU Joint Institute Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China School of Physics and Astronomy Cardiff UniversityCardiff CF243AAWalesUK Department of Electrical and Computer Engineering Yale UniversityNew HavenCT 06511USA Energy Sciences Institute Yale UniversityWest HavenCT 06516USA Future Photovoltaics Research Center Global Institute of Future TechnologyShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Electrical energy is essential for modern society to sustain economic *** soaring demand for the electrical energy,together with an awareness of the environmental impact of fossil fuels,has been driving a shift towards the utilization of solar ***,traditional solar energy solutions often require extensive spaces for a panel installation,limiting their practicality in a dense urban *** overcome the spatial constraint,researchers have developed transparent photovoltaics(TPV),enabling windows and facades in vehicles and buildings to generate electric *** TPV advancements are focused on improving both transparency and power output to rival commercially available silicon solar *** this review,we first briefly introduce wavelength-and non-wavelengthselective strategies to achieve *** of merit and theoretical limits of TPVs are discussed to comprehensively understand the status of current TPV *** we highlight recent progress in different types of TPVs,with a particular focus on solution-processed thin-film photovoltaics(PVs),including colloidal quantum dot PVs,metal halide perovskite PVs and organic *** applications of TPVs are also reviewed,with emphasis on agrivoltaics,smart windows and ***,current challenges and future opportunities in TPV research are pointed out.

关键词： Transparent semiconductors Solution-processable transparent solar cell Emerging solar cell materials Buildingintegrated photovoltaics

Brain-derived neurotrophic factor signaling in the neuromuscular junction during developmental axonal competition and synapse elimination

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 394-401页

作者： Josep Tomàs Víctor Cilleros-mañé Laia Just-Borràs marta Balanyà-Segura Aleksandra Polishchuk Laura Nadal marta Tomàs Carolina Silvera-Simón manel m.Santafé maria A.Lanuza Unitat d’Histologia i Neurobiologia(UHNeurob) Facultat de Medicina i Ciències de la SalutUniversitat Rovira i VirgiliReusSpain

During the development of the nervous system,there is an overproduction of neurons and *** competition between neighboring nerve endings and synapses performing different activity levels leads to their elimination or *** have extensively studied the involvement of the brain-derived neurotrophic factor-Tropomyosin-related kinase B receptor neurotrophic retrograde pathway,at the neuromuscular junction,in the axonal development and synapse elimination process versus the synapse *** purpose of this review is to describe the neurotrophic influence on developmental synapse elimination,in relation to other molecular pathways that we and others have found to regulate this *** particular,we summarize our published results based on transmitter release analysis and axonal counts to show the different involvement of the presynaptic acetylcholine muscarinic autoreceptors,coupled to downstream serine-threonine protein kinases A and C(PKA and PKC)and voltage-gated calcium channels,at different nerve endings in developmental *** dynamic changes that occur simultaneously in several nerve terminals and synapses converge across a postsynaptic site,influence each other,and require careful studies to individualize the mechanisms of specific *** describe an activity-dependent balance(related to the extent of transmitter release)between the presynaptic muscarinic subtypes and the neurotrophin-mediated TrkB/p75NTR pathways that can influence the timing and fate of the competitive interactions between the different axon *** downstream displacement of the PKA/PKC activity ratio to lower values,both in competing nerve terminals and at postsynaptic sites,plays a relevant role in controlling the elimination of supernumerary ***,calcium entry through L-and P/Q-subtypes of voltage-gated calcium channels(both channels are present,together with the N-type channel in developing nerve terminals)contributes to red

关键词： acetylcholine release adenosine receptors axonal competition brain-derived neurotrophic factor calcium channels motor end-plate muscarinic acetylcholine receptors postnatal synapse elimination serine kinases tropomyosin-related kinase receptorB