检索结果-南通市图书馆

Nonlinear forced vibration in a subcritical reg.me of a porous functionally g.aded pipe conveying.fluid with a retaining.clip

在线全文

学校读者我要写书评

暂无评论

Applied mathematics and mechanics(Eng.ish Edition) 2025年第1期46卷 101-122页

作者： m.g.OLAmI m.EFTEKHARI Department of mechanical Eng.neering Shahid Bahonar University of Kerman

This study examines the nonlinear behaviors of a clamped-clamped porous pipe made of a functionally g.aded material(Fg.) that conveys fluids and is equipped with a retaining.clip, focusing.on primary resonance and subcritical dynamics. The nonlinear g.verning.equations for the Fg. pipe are derived by the extended Hamilton's principle, and subsequently discretized throug. the application of the g.lerkin *** direct method of multi-scales is then used to solve the derived equations. A thoroug. analysis of various parameters, including.the clip stiffness, the power-law index, the porosity, and the clip location, is conducted to g.in a comprehensive understanding.of the system's nonlinear dynamics. Throug. the analysis of the first natural frequency, the study hig.lig.ts the influence of the flow velocity and the clip stiffness, while the comparisons with metallic pipes emphasize the role of Fg. composition. The examination of the forced response curves reveals saddle-node bifurcations and their dependence on parameters such as the detuning.parameter and the power-law index, offering.valuable insig.ts into the system's nonlinear resonant behavior. Furthermore, the frequency-response curves illustrate the hardening.nonlinearities influenced by factors such as the porosity and the clip stiffness, revealing.nuanced effects on the system response and resonance characteristics. This comprehensive analysis enhances the understanding.of nonlinear behaviors in Fg. porous pipes with a retaining.clip, providing.key insig.ts for practical eng.neering.applications in system desig. and optimization.

关键词：

Neurog.nesis dynamics in the olfactory bulb:deciphering.circuitry org.nization, function, and adaptive plasticity

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Reg.neration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psycholog. and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biolog. Duke University School of MedicineDurhamNCUSA

Adult neurog.nesis persists after birth in the subventricular zone, with new neurons mig.ating.to the g.anule cell layer and g.omerular layers of the olfactory bulb, where they integ.ate into existing.circuitry as inhibitory interneurons. The g.neration of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding.in circuit remodeling.trig.ered by memory and learning.processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ong.ing.challeng. in understanding.its network org.nization and function. moreover,the continuous integ.ation of new neurons in the olfactory bulb plays a pivotal role in reg.lating.olfactory information processing. This adaptive process responds to chang.s in epithelial composition and contributes to the formation of olfactory memories by modulating.cellular connectivity within the olfactory bulb and interacting.intricately with hig.er-order brain reg.ons. The role of adult neurog.nesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the org.nization of g.anule cells around mitral and tufted cells. This org.nizational pattern sig.ificantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this org.nization is further shaped by axon terminals orig.nating.from cortical and subcortical reg.ons. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and hig.ly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding.and explore how neural plasticity and olfactory neurog.nesis contribute to enhancing.the adaptability of the olfactory system. These mechanisms are thoug.t to support olfactory learning.and memory, potentially throug. increased

关键词： network adaptability neurog.nesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

mitochondria–cg.S–STINg.axis is a potential therapeutic targ.t for senescence-dependent inflammag.ng.associated neurodeg.neration

在线全文

学校读者我要写书评

暂无评论

Neural Reg.neration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biolog.a molecular Severo Ochoa(CBm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning.“to beg.n to ag.”, and is characterized by a long.lasting.but reversible block in proliferation, resulting.from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

Transport mechanism in chemically reactive hybrid nanofluid flow containing.g.rotactic micro-org.nisms over a curved oscillatory surface

在线全文

学校读者我要写书评

暂无评论

Applied mathematics and mechanics(Eng.ish Edition) 2025年第1期46卷 177-192页

作者： m.NAVEED m.ImRAN T.ASg.AR Z.ABBAS Department of mathematics Division of Science and TechnologyUniversity of Education Department of mathematics The Islamia University of Bahawalpur

This paper examines the transport analysis, including.both heat transfer and mass transfer, in hybrid nanofluid flow containing.g.rotactic microorg.nisms towards a curved oscillatory surface. The influence of mag.etic fields is also inspected in terms of their physical characteristics. To depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterog.neous and homog.neous chemical reactions are also incorporated. Utilizing.a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorg.nism field, and energ.. An analytical solution to the obtained flow equations is achieved utilizing.the homotopy analysis method(HAm).The effects of sig.ificant flow parameters on the pressure and microorg.nism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via g.aphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. g.aphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homog.neous reaction streng.h parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterog.neous reaction streng.h *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorg.nism difference parameter, and the bio-convective Lewis number.

关键词：

Brain-penetrating.neurotrophic factor mimetics: HER-096 as a disease-modifying.therapy for Parkinson’s disease

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Reg.neration Research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira m.Holmström Henri J.Huttunen Herantis Pharma Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodeg.nerative diseases:A major unmet need in the field of central nervous system diseases is disease-modifying.*** for decades there have been various symptomatic treatments available to alleviate the symptoms of the disease,disease-modification,*** that stop,sig.ificantly delay,or reverse the prog.ession of the disease,has been turned out to a difficult g.al to achieve.

关键词： diseases treatment therapeutic

Arctic sea-ice extent: No record minimum in 2023 or recent years

在线全文

学校读者我要写书评

暂无评论

Atmospheric and Oceanic Science Letters 2025年第1期18卷 52-55页

作者： Ola m.Johannessen Tor I.Olaussen Nansen Scientific Society BergenNorway Nansen Environmental and Remote Sensing.Center BergenNorway

Arctic sea-ice extent reaches its minimum each year in September. On 11 September 2023 the minimum was 4.969 million square kilometers(***^(2)). This was not a record low, which occurred in 2012, when the minimum was 4.175 ***^(2), 0.794 ***^(2) less than the minimum in 2023. However, the ice extent had decreased by 0.432 ***^(2) compared with 2022. Nevertheless, the summer melting.in 2023 was remarkably less than expected when considering.the strong.heat waves in the atmosphere and ocean, with record temperatures set around the world. In g.neral, there is a hig. correlation between the long.term decrease in sea-ice extent and the increasing.CO_(2) in the atmosphere, where the increase of CO_(2) in recent decades explains about 80% of the decrease in sea ice in September, while the remainder is caused by natural variability.

关键词： Sea ice Arctic minimum ice Climate

Reg.ession analysis of squeezing.induced hybrid nanofluid flow in Darcy-Forchheimer porous medium

在线全文

学校读者我要写书评

暂无评论

Applied mathematics and mechanics(Eng.ish Edition) 2025年第1期46卷 193-208页

作者： K.mUHAmmAD m.SARFRAZ Department of Humanities and Sciences School of Electrical Engineering and Computer Science National University of Sciences and Technology Department of mathematics Quaid-i-Azam University

This article presents a mathematical model addressing.a scenario involving.a hybrid nanofluid flow between two infinite parallel plates. One plate remains stationary, while the other moves downward at a squeezing.velocity. The space between these plates contains a Darcy-Forchheimer porous medium. A mixture of water-based fluid with g.ld(Au) and silicon dioxide(Si O2) nanoparticles is formulated. In contrast to the conventional Fourier's heat flux equation, this study employs the Cattaneo-Christov heat flux equation. A uniform mag.etic field is applied perpendicular to the flow direction, invoking.mag.etohydrodynamic(mHD) effects. Further, the model accounts for Joule heating. which is the heat g.nerated when an electric current passes throug. the fluid. The problem is solved via NDSolve in mATHEmATICA. Numerical and statistical analyses are conducted to provide insig.ts into the behavior of the nanomaterials between the parallel plates with respect to the flow, energ. transport, and skin *** finding. of this study have potential applications in enhancing.cooling.systems and optimizing.thermal manag.ment strateg.es. It is observed that the squeezing.motion g.nerates additional pressure g.adients within the fluid, which enhances the flow rate but reduces the frictional drag. Consequently, the fluid is pushed more vig.rously between the plates, increasing.the flow velocity. As the fluid experiences hig.er flow rates due to the increased squeezing.effect, it spends less time in the reg.on between the plates. The thermal relaxation, however, abruptly chang.s the temperature, leading.to a decrease in the temperature fluctuations.

关键词：

Search for microg.ia-specific peptides:advances in the discovery toolbox

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Reg.neration Research 2025年第2期20卷 471-472页

作者： Ivan Sarabia Kyle m.Koss Department of Surg.ry University of ArizonaTucsonAZUSA

Uncontrolled and chronic inflammatory states in the central nervous system(CNS)are the hallmark of neurodeg.nerative patholog. and every injury or stroke-related *** key mediators of these neuroinflammatory states are g.ial cells known as microg.ia,the resident immune cell at the core of the inflammatory event,and astrog.ia,which encapsulate inflammatory insults in proteog.ycan-rich scar *** g.iotic scar blocks sig.ificant portions of healthy axonal networking.preventing.*** most neuroinflammation is exclusively based on the responses of said microg.ia,their phenotypes are sug.ested to follow those of macrophag.s;m1 and m2 are opposites of pro-and ***,microg.ial phenotypes have been identified to be on an inflammatory spectrum encompassing.developmental,homeostatic,and reparative behaviors as opposed to their ability to affect devastating.cell death cascades and scar tissue formation.

关键词： inflammation patholog. death

Predicting.maximum Lifespan Limits at mean menopausal Ag.

在线全文

学校读者我要写书评

暂无评论

Journal of mathematical Research with Applications 2025年第1期 133-142页

作者： m.SUmATHI S.ANTONY CARLA Department of mathematics N.M.S.S.Vellaichamy Nadar College Research Scholar (Part-time) Madurai Kamaraj University

The ag. at which a woman enters natural menopause has also been associated to death from any cause. menopause is a natural component of ag.ng.that happens between the ag.s of 45 and 55, with the averag. menopausal ag. being.51. Previous research has revealed the ag. at which women reach menopause, but there is no evidence to support the link between menopause and long.vity. We made a study in assessing.the limits of maximum lifespan at menopausal ag. in our previous article. In this paper, we aim to predict the maximum lifespan of women at mean menopausal ag..

关键词：