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The challenging management of malignant ureteral obstruction:Analysis of a series of 188 cases

Current Urology 2024年第1期18卷 34-42页

作者： Alberto Artiles medina Inés Laso garcía Fernando González Tello Sara Álvarez Rodríguez m.nuel Hevia Palacios marina mata Alcaraz César mínguez Ojeda Fernando Arias Funez Victoria Gómez Dos Santos Francisco Javier Burgos Revilla Department of Urology Hospital Universitario Ramón y CajalMadridSpain Department of Radiology Hospital Universitario Ramón y CajalMadridSpain

Background:malignant ureteral obstruction(mUO)is a common condition that complicates the course of advanced *** aims of this study are to analyze the causes,management,and survival of patients with obstructive nephropathy due to malignant ureteric obstruction and to determine prognostic ***,we studied the complications and outcomes in patients who underwent urinary *** and methods:A retrospective study was conducted on patients with computed tomography-confirmed mUO between January 2016 and November ***,clinical,radiological,laboratory,and management data were *** curves were estimated using the Kaplan-meier method,and univariate and multivariate Cox proportional hazards models were used to test the association between parameters and ***:A total of 188 patients were *** mean age was 69.01 years(SD,14.95 years),and the majority(54.8%)were *** most common mechanism leading to mUO was compression by a pelvic mass(36.9%),and the 3 most frequent tumors causing mUO were prostate(17.6%),bladder(16.5%),and rectal cancer(11.7%).Forty-seven patients(25%)underwent urinary diversion:23(48.9%)underwent double-J stenting and 21(44.7%)underwent percutaneous *** most common reason for urinary diversion was acute kidney injury(53.3%).Recovery of renal function was observed in 55.8%of the patients after urinary *** most frequently identified complications after urinary diversion were urinary tract infection(24.4%),hematuria(17.0%),and urinary sepsis(14.9%).The median survival after hydronephrosis diagnosis was 6.43 months(interquartile range,1.91-14.81 months).In patients who underwent urinary decompression,the median survival after urinary diversion was 8.67 months(interquartile range,2.99-17.28 months).In the multivariate analysis,a lower grade of hydronephrosis and cancer cachexia negatively impacted ***:Cancer patients with mUO have a poor pro

关键词： Hydronephrosis Ureteral obstruction Neoplasms Urinary diversion Survival Prognosis

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Frequency-dependent viscoelasticity effects on the wave attenuation performance of multi-layered periodic foundations

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Applied mathematics and mechanics(English Edition) 2024年第3期45卷 407-424页

作者： m.SAFI m.VAKILIFARD m.J.mAHmOODI Faculty of Civil Water&Environmental EngineeringShahid Beheshti UniversityTehran ***Iran Faculty of mechanical and Energy Engineering Shahid Beheshti UniversityTehran ***Iran

In this paper,layered periodic foundations(LPFs)are numerically examined for their responses to longitudinal and transverse modes in the time and frequency *** different unit-cells,i.e.,2-layer,4-layer,and 6-layer unit-cells,comprising concrete/rubber,concrete/rubber/steel/rubber,and concrete/rubber/steel/rubber/lead/rubber materials,respectively,are taken into ***,the viscoelasticity behavior of the rubber is modeled with two factors,i.e.,a frequency-independent(FI)loss factor and a linear frequency-dependent(FD)loss *** the extraction of the complex dispersion curves and the identification of the band gaps(BGs),the simulations of wave transmission in the time and frequency domains are performed using the COmSOL *** parametric studies evaluate the effects of the rubber viscoelasticity models on the dispersion curves and the wave transmission for the longitudinal and transverse *** results show that considering the rubber viscoelasticity enhances the wave attenuation ***,the transverse-mode damping is more sensitive to the viscoelasticity model than its longitudinal *** 6-layer unit-cell LPF exhibits the lowest BG,ranging from 4.8 Hz to 6.5 Hz.

关键词： layered metamaterial periodic foundation complex dispersion curve wave transmission diagram

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Experimental and computational study of smoke dynamics from multiple fire sources inside a large-volume building

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Building Simulation 2021年第4期14卷 1147-1161页

作者： Gabriele Vigne Wojciech Węgrzyński Alexis Cantizano Pablo Ayala Guillermo Rein Cándido gutiérrez-montes Fluid Dynamics Division of the Department of mining and mechanical Engineering Universidad de JaénJaénSpain Institute for Research in Technology ICAIUniversidad Pontificia ComillasMadridSpain Building Research Institute(ITB) WarsawPoland Imperial College London LondonUK JVVA Fire&Risk MadridSpain

Fire in large-volume buildings poses separate and distinct challenges from compartmented *** particular,the risk it poses on life safety is mostly due to the smoke it produces,its effects on the evacuation process,and how it can affect the firefighters when they approach the building to fight the fire and rescue the *** is why smoke control in large-volume enclosures is of utter importance for life safety,property protection and business *** research presents an experimental and numerical study of the smoke dynamics from four fire sources(combined heat release rate of 5.2 mW)with different ignition times and under transient ventilation conditions,inside a 20 m high cubic *** measurements in the plume and close to the walls have been recorded using 59 *** data was used in the determination of the smoke layer interface height,with the least-square and the N-Percent *** show that significantly worse conditions are induced by multiple sources than those in a single fire of equal *** results have been obtained using the computational fluid dynamics code FDS(Fire Dynamics Simulator,v6.7.1).The comparison shows that in the far field the temperature predictions are accurate inside the smoke layer(10 m and 15 m)with discrepancies lower than 10%,whereas higher significant discrepancies were observed at the smoke layer interface,i.e.5 m high,with discrepancies up to 20%.Furthermore,a grid analysis has been performed showing that grid resolutions,D*/δ,based on the global HRR of the fire might be sufficient to predict the fire induced conditions far from the *** analysis confirmed the applicability of FDS to the assessment of the smoke dynamics under complex fire conditions away from ***,the present work shows the importance of considering fires with multiple sources due to the faster smoke production compared with single fires.

关键词： experiments simulation fire buildings FDS CFD

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Hematological abnormalities in liver cirrhosis

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World Journal of Hepatology 2024年第9期16卷 1229-1244页

作者： Oscar m.nuel Fierro-Angulo JoséAlberto González-Regueiro Ariana Pereira-garcía Astrid Ruiz-margáin Fernando Solis-Huerta Ricardo Ulises macías-Rodríguez Department of Gastroenterology Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico 14080Mexico Department of Hematology Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMexico 14080Mexico

Hematological abnormalities are common in cirrhosis and are associated with various pathophysiological *** have documented a prevalence of thrombocytopenia,leukopenia,and anemia in patients with compensated cirrhosis of 77.9%,23.5%,and 21.1%,*** abnormalities carry significant clinical implications,including considerations for invasive procedures,infection risk,bleeding risk,and ***,cirrhosis was believed to predispose patients to bleeding due to alterations observed in classical coagula-tion tests such as prothrombin time,partial thromboplastin time,international normalized ratio,and ***,this understanding has evol-ved,and cirrhosis patients are now also acknowledged as being at a high risk for thrombotic *** in cirrhosis patients presents a complex pheno-type,with procoagulant and anticoagulant abnormalities offsetting each *** multifactorial phenomenon is inadequately reflected by routine laboratory *** complications are more prevalent in decompensated cirrhosis and may correlate with disease *** is primarily associated with portal hypertension,endothelial dysfunction,mechanical vessel injury,dissem-inated intravascular coagulation,endotoxemia,and renal *** review comprehensively outlines hematologic index abnormalities,mechanisms of hemostasis,coagulation,and fibrinolysis abnormalities,limitations of laboratory testing,and clinical manifestations of bleeding and thrombosis in patients with liver cirrhosis.

关键词： Cirrhosis Anemia Leukopenia Thrombocytopenia Coagulopathy Bleeding Thrombosis

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Seasonal variation in native hydraulic conductivity between two deciduous oak species

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Journal of Plant Ecology 2020年第1期13卷 78-86页

作者： Dilia mota-gutiérrez Guadalupe Arreola-González Rafael Aguilar-Romero Horacio Paz Jeannine Cavender-Bares Ken Oyama Antonio Gonzalez-Rodriguez Fernando Pineda-garcía Facultad de Biología Universidad Michoacana de San Nicolás de Hidalgo.Edificio RCiudad UniversitariaGral.Francisco J.Múgica S/N A-1Felicitas de Río58030 MoreliaMichoacánMexico Escuela Nacional de Estudios Superiores Unidad MoreliaUniversidad Nacional Autónoma de México.Antigua Carretera a Pátzcuaro 8701Ex-Hacienda de San Joséde La Huerta58190 MoreliaMichoacánMexico Instituto de Investigaciones en Ecosistemas y Sustentabilidad Campus MoreliaUniversidad Nacional Autónoma de México.Antigua Carretera a Pátzcuaro 8701Ex-Hacienda de San Joséde La Huerta58190 MoreliaMichoacánMexico Deparment of Ecology Evolution and BehaviorUniversity of MinnesotaSaint PaulMN 55108USA

Aims mechanisms of plant drought resistance include both tolerance and *** vulnerability to embolism and turgor loss point are considered traits that confer tolerance,while leaf abscission and deciduousness characterizes the avoidance *** these mechanisms are thought to trade-off expressing a continuum among species,little is known on how variation in the timing and duration of leaf shedding in response to drought affect the relationship between xylem and leaf *** the present study,we explored the extent to which drought tolerance differs between two oak(Quercus)species that exhibit different leaf shedding ***,we predicted that *** Trel.,which loses leaves at the end of the dry season(late-deciduous)and is thus exposed to a greater risk of cavitation,would be more drought tolerant and more conservative in its water use than *** Liebm.,which loses its leaves for only a short period of time in the middle of the dry season(brevideciduous).methods The study was conducted in central mexico in a single population of each of the two oak species,separated from each other by a distance of 1.58 km,and by an altitudinal difference of 191 *** deserticola(late deciduous)is more frequent down slope,while ***(brevideciduous)tends to occur at higher elevations along the *** assessed seasonal differences(rainy versus dry season)in native stem hydraulic conductivity,and tested for variation in xylem vulnerability to cavitation,leaf water use and leaf turgor loss point between the two *** Findings The two oak species did not differ in traits conferring drought tolerance,including xylem vulnerability to embolism,leaf turgor loss point,or stomatal ***,both species had different performance during the dry season;the brevideciduous species had lower negative impact in the xylem function than the late-deciduous ***,seasonal changes in plant physiological performance

关键词： Quercus hydraulic conductivity embolisms leaf phenology

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Engineering of efficient visible light photocatalysts:Ti_(1-x+y)Cu_(x)La_(y)O_(2)(x=0.03;y=0,0.005,0.01) compositions

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Journal of Rare Earths 2024年第3期42卷 497-505,I0003页

作者： S.m.Yakout A.m.Youssef Inorganic Chemistry Department National Research Centre(NRC)El Buhouth StDokkiCairo12622Egypt

In dye-photocatalysis, widening the wavelengths absorption range of catalysts as well as aborting the recombination of the photoexcited charge carriers(electrons-holes pairs) are of paramount *** the current study, we report the photocatalytic characteristics of four compositions composed of TiO_(2),Ti_(0.97)Cu_(0.03)O_(2), Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)powders for two harmful dyes(Congo red and methylene blue). The X-ray diffraction technique verified the configuration of mixed anatase and rutile phases in pure TiO_(2)and Ti_(0.97)Cu_(0.03)O_(2)powders while Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)powders possess anatase phase only. The changes of the band gap structure and dimensions of the unit cell volume of TiO_(2)confirm the substitution of Ti^(4+)sites by Cu^(2+)and La^(3+)ions. Remarkable widening of wavelengths absorption with formation of long absorption tails were found in TiO_(2)(3.13 e V) through insertion of La^(3+)plus Cu^(2+)ions. Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)samples exhibit a visible light band gap of 2.3 and 2.7 e V, respectively. Based on SEm images, incorporation of Cu^(2+)and La^(3+)ions influences the surface morphology of TiO_(2). The resulting Ti_(0.97)Cu_(0.03)O_(2), Ti_(0.965)Cu_(0.03)La_(0.005)O_(2)and Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)powders present enhanced photocatalytic activity towards Congo red dye degradation compared to pure one under natural solar spectrum. The best Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)catalyst exhibits superior photocatalytic activity of 96% for 10 ppm CR dye in 20 min as well as above average photocatalytic efficiency of 63% for 30 ppm CR dye in 120 min. As well, it showed acceptable photodegradation activity of 52% for 30 ppm mB solution in 140 min of sunlight irradiation. The heightened photodegradation efficiency of Ti_(0.96)Cu_(0.03)La_(0.01)O_(2)catalyst can be clarified in terms of higher ch

关键词： Semiconductor TiO_(2) Rare earths Congo red methylene blue Solar spectrum Photodegradation

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Influence of temperature and salinity on hydrodynamic forces

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Journal of Ocean Engineering and Science 2016年第4期1卷 325-336页

作者： A.Escobar V.Negro J.S.López-gutiérrez m.D.Esteban Technical University of madrid C/Profesor Aranguren S/N28040 MadridSpain

The purpose of this study is to introduce an innovative approach to offshore engineering so as to take variations in sea temperature and salinity into account in the calculation of hydrodynamic *** this in mind,a thorough critical analysis of the influence of sea temperature and salinity on hydrodynamic forces on piles like those used nowadays in offshore wind farms will be carried *** influence on hydrodynamic forces occurs through a change in water density and viscosity due to temperature and salinity ***,the aim here is to observe whether models currently used to estimate wave forces on piles are valid for different ranges of sea temperature and salinity apart from observing the limit when diffraction or nonlinear effects arise combining both effects with the magnitude of the pile ***,specific software has been developed to simulate equations in fluid mechanics taking into account nonlinear and diffraction *** software enables wave produced forces on a cylinder supported on the sea bed to be *** study includes observations on the calculation model’s sensitivity as to a variation in the cylinder’s diameter,on the one hand and,on the other,as to temperature and salinity *** software will enable an iterative calculation to be made for finding out the shape the pressure wave caused when a wave passes over will have for different pile diameters and water with different temperature and salinity.

关键词： Sea temperature Salinity Hydrodynamic forces Wave action Offshore wind farms

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Pancreatic and pulmonary mast cells activation during experimental acute pancreatitis

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World Journal of Gastroenterology 2010年第27期16卷 3411-3417页

作者： Inmaculada Lopez-Font Sabrina Gea-Sorlí Enrique de-madaria Luis m gutiérrez miguel Pérez-mateo Daniel Closa Gastroenterology Unit University General Hospital Alicante Spain Department of Experimental Pathology Institute of Biomedical Research of Barcelona Spanish National Research Council(IIBB-CSIC)Institute of Biomedical Research August Pi Sunyer(IDIBAPS) and Biomedical Research Centre Network on Liver and Digestive Diseases Neurosciences Institute Miguel Hernandez University-Spanish National Research Council(UMH-CSIC)Sant Joan d'Alacant miguel Hernandez University School of Medicine

AIm:To study the activation of pancreatic and pulmonary mast cells and the effect of mast cell inhibition on the activation of peritoneal and alveolar macrophages during acute ***:Pancreatitis was induced by intraductal infusion of 5% sodium taurodeoxycholate in *** mast cell inhibitor cromolyn was administered intraperitoneally(i.p.) 30 min before pancreatitis *** pancreatic and pulmonary tissue damage was evaluated histologically and mast cells and their state of activation were *** and alveolar macrophages were obtained and the expression of tumor necrosis factor α was *** activity was measured to evaluate the effect of mast cell inhibition on the progression of the inflammatory ***,the effect of plasma on cultured mast cells or macrophages was evaluated in ***:The mast cell stabilizer signif icantly reduced inflammation in the pancreas and lung and the activation of alveolar macrophages but had no effect on peritoneal *** cell degranulation was observed in the pancreas during pancreatitis but no changes were observed in the *** from rats with pancreatitis could activate alveolar macrophages but did not induce degranulation of mast cells in ***:Pancreatic mast cells play an important role in triggering the local and systemic inflammatory response in the early stages of acute *** contrast,lung mast cells are not directly involved in the inflammatory response related to pancreatic damage.

关键词： Cytokines Inflammation macrophages mast cells Pancreatitis

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Nonlinear dynamic modeling of planar moving Timoshenko beam considering non-rigid non-elastic axial effects

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Applied mathematics and mechanics(English Edition) 2024年第3期45卷 479-496页

作者： m.ABBASI GAVARI m.R.HOmAEINEZHAD Faculty of mechanical Engineering K.N.Toosi University of TechnologyTehran 19991-43344Iran

Due to the importance of vibration effects on the functional accuracy of mechanical systems,this research aims to develop a precise model of a nonlinearly vibrating single-link mobile flexible *** manipulator consists of an elastic arm,a rotary motor,and a rigid carrier,and undergoes general in-plane rigid body motion along with elastic transverse *** accurately model the elastic behavior,Timoshenko’s beam theory is used to describe the flexible arm,which accounts for rotary inertia and shear deformation *** applying Newton’s second law,the nonlinear governing equations of motion for the manipulator are derived as a coupled system of ordinary differential equations(ODEs)and partial differential equations(PDEs).Then,the assumed mode method(Amm)is used to solve this nonlinear system of governing equations with appropriate shape *** assumed modes can be obtained after solving the characteristic equation of a Timoshenko beam with clamped boundary conditions at one end and an attached mass/inertia at the *** addition,the effect of the transverse vibration of the inextensible arm on its axial behavior is *** the axial rigidity,the effect makes the rigid body dynamics invalid for the axial behavior of the ***,numerical simulations are conducted to evaluate the performance of the developed model,and the results are compared with those obtained by the finite element *** comparison confirms the validity of the proposed dynamic model for the *** to the mentioned features,this model can be reliable for investigating the system’s vibrational behavior and implementing vibration control algorithms.

关键词： planar moving Timoshenko beam non-rigid non-elastic axial effect as-sumed mode method(Amm) nonlinear motion analysis

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Free vibration and buckling analysis of polymeric composite beams reinforced by functionally graded bamboo fbers

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Applied mathematics and mechanics(English Edition) 2024年第3期45卷 543-562页

作者： H.m.FEIZABAD m.H.YAS Department of mechanical Engineering Razi UniversityKermanshah ***Iran

Natural fibers have been extensively researched as reinforcement materials in polymers on account of their environmental and economic advantages in comparison with synthetic fibers in the recent *** fibers are renowned for their good mechanical properties,abundance,and short cycle *** beams are one of the fundamental structural components and are susceptible to mechanical loads in engineering applications,this paper performs a study on the free vibration and buckling responses of bamboo fiber reinforced composite(BFRC)beams on the elastic *** different functionally graded(FG)layouts and a uniform one are the considered distributions for unidirectional long bamboo fibers across the *** elastic properties of the composite are determined with the law of *** Hamilton’s principle,the governing equations of motion are *** generalized differential quadrature method(GDQm)is then applied to the equations to obtain the *** achieved outcomes exhibit that the natural frequency and buckling load values vary as the fiber volume fractions and distributions,elastic foundation stiffness values,and boundary conditions(BCs)and slenderness ratio of the beam ***,a comparative study is conducted between the derived analysis outcomes for BFRC and homogenous polymer beams to examine the effectiveness of bamboo fibers as reinforcement materials,demonstrating the significant enhancements in both vibration and buckling responses,with the exception of natural frequencies for cantilever beams on the Pasternak foundation with the FG-◇fiber ***,the obtained analysis results of BFRC beams are also compared with those for carbon nanotube reinforced composite(CNTRC)beams found in the literature,indicating that the buckling loads and natural frequencies of BFRC beams are lower than those of CNTRC beams.

关键词： bamboo fiber free vibration buckling analysis functionally graded(FG)beam elastic foundation generalized differential quadrature method(GDQm)

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