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Exercise-induced hypoalgesia in chronic neck pain: A narrative review

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Sports medicine and Health Science 2024年第1期6卷 37-47页

作者： Fernando Rojas-Galleguillos Cecilia Clark-Hormazabal Eduardo mendez-fuentes Francisco Guede-Rojas Cristhian mendoza Andres Riveros Valdes Claudio Carvajal-Parodi Universidad San Sebastian Programa Magíster en Kinesiología MusculoesqueleticaLientur#1457ConcepcionChile Exercise and Rehabilitation Sciences Laboratory School of Physical TherapyFaculty of Rehabilitation SciencesUniversidad Andres BelloSantiago7591538Chile Universidad San Sebastian Laboratoriode NeurobiologíFacultad de Odontologíay Ciencias dela RehabilitacionLientur#1457ConcepcionChile Universidad San Sebastian Departamento de Ciencias MorfologicasFacultad de MedicinaCienciaLientur#1457ConcepcionChile Universidad San Sebastian Escuelade KinesiologíaFacultad de OdontologíaCiencias dela RehabilitacionLientur#1457ConcepcionChile

Chronic neck pain(CNP)is a worldwide health problem with several risk *** of the most widely used treatments for managing this condition is therapeutic exercise,which could generate a response called exerciseinduced hypoalgesia(EIH).There is no consensus on the best exercise modality to induce ***,this review aims to analyze and synthesize the state-of-the-art about the hypoalgesic effect of exercise in subjects with *** included articles on EIH and CNP in patients older than 18 years,with pain for more than three months,where the EIH response was *** that studied CNP associated with comorbidities or measured the response to treatments other than exercise were *** studies reviewed reported variable *** in healthy subjects has been shown to reduce indicators of pain sensitivity;however,in people with chronic pain,the response is *** investigations reported adverse effects with increased pain intensity and decreased pain sensitivity,others found no clinical response,and some even reported EIH with decreased pain and increased *** is an identifiable,stimulable,and helpful therapeutic response in people with *** research is still needed on subjects with CNP to clarify the protocols and therapeutic variables that facilitate the EIH *** addition,it is necessary to deepen the knowledge of the intrinsic and extrinsic factors that influence EIH in people with CNP.

关键词： Exercise-induced hypoalgesia Neck pain Chronic pain Neck exercise therapy

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仿生土木工程研究进展与展望

土木与环境工程学报（中英文） 2024年第5期46卷 1-15页

作者：仉文岗何祥嵘刘汉龙孙伟鑫韩馥柽 Raul fuentes Gustavo Paneiro 重庆大学土木工程学院重庆400045 亚琛工业大学土木工程学院德国亚琛100600 里斯本大学建筑学院葡萄牙里斯本1649-004

随着城镇化水平不断提升,中国每年新增建筑面积约20亿m2,大规模基础设施建设对土木工程理论和技术创新的要求越来越高。学者们通过研究自然界的增强增韧、水下黏合、钻孔掘进和轻质高强等现象发现,生物体具有独特的外部形态和组织结构,... 详细信息

随着城镇化水平不断提升,中国每年新增建筑面积约20亿m2,大规模基础设施建设对土木工程理论和技术创新的要求越来越高。学者们通过研究自然界的增强增韧、水下黏合、钻孔掘进和轻质高强等现象发现,生物体具有独特的外部形态和组织结构,通过模仿生物体的外部形态、结构特征或运动机理可为土木工程技术创新和可持续发展提供新思路、新原理和新理论。从仿生材料、仿生结构和仿生机械与构筑物3个方面阐述仿生学在土木工程中的应用,列举典型的应用案例,并对仿生土木工程进行总结和展望,为未来的研究提供基础材料。作为新兴的研究方向,仿生土木工程基础理论尚不完善,仿生土木工程涉及生物、材料、结构等多学科的交叉,需要开展不同领域间的协同合作研究。

关键词：仿生土木工程仿生材料仿生结构仿生机械与构筑物

The new kid on the block in insect pest management:sprayable RNAi goes commercial

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Science China(Life Sciences) 2024年第8期67卷 1766-1768页

作者： Junjie Yan Ralf Nauen Stuart Reitz Andrei Alyokhin Jiang Zhang David mota-Sanchez Yonggyun Kim Subba Reddy Palli Silvia I.Rondon Brian A.Nault Juan Luis Jurat-fuentes michael S.Crossley William E.Snyder Angharad m.R.Gatehouse myron P.Zalucki Bruce E.Tabashnik Yulin Gao State Key Laboratory for Biology of Plant Disease and Insect Pests Institute of Plant ProtectionChinese Academy of Agricultural SciencesBeijing 100193China Bayer AG Crop Science DivisionR&DPest ControlMonheim 40789Germany Department of Crop and Soil Science Oregon State UniversityOntario 97914USA School of Biology and Ecology University of MaineOrono 04469USA Shenzhen Branch Guangdong Laboratory of Lingnan Modern AgricultureKey Laboratory of Synthetic BiologyMinistry of Agriculture and Rural AffairsAgricultural Genomics Institute at ShenzhenChinese Academy of Agricultural SciencesShenzhen 518000China Department of Entomology Michigan State UniversityEast Lansing 48864USA Department of Plant medicals Andong National UniversityAndong 36729Republic of Korea Department of Entomology University of KentuckyLexington 40503USA Oregon State University Oregon Integrated Pest Management CenterCorvallis 97838USA Department of Entomology Cornell UniversityCornell AgriTechGeneva 14456USA Department of Entomology and Plant Pathology University of TennesseeKnoxville 37996USA Department of Entomology and Wildlife Ecology University of DelawareNewark 19716USA Department of Entomology University of GeorgiaAthensGeorgia 30602USA School of Natural and Environmental Sciences Newcastle UniversityNewcastle upon TyneNE17RUUK School of the Environment University of QueenslandBrisbane 4072Australia Shandong Engineering Research Center for Environment-Friendly Agricultural Pest management College of Plant Health and MedicineQingdao Agricultural UniversityQingdao 266109China Department of Entomology University of ArizonaTucson 85721USA National Center of Excellence for Tuber and Root Crop Research Chinese Academy of Agricultural SciencesBeijing 100081China

Insect pest damage to crops is a threat to global food security(Tilman et al.,2011).Climate change,the evolution of insecticide resistance,and the phasing out of insecticides due to environmental and safety concerns exacerbate this *** urgently need safe and effective crop protection tools to sustainably generate yields that meet ever-increasing global demand.

关键词： crops damage pest

Analysis of Citizen Participation in Urban Planning of Comala,Colima,mexico-A Secondary Publication

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Journal of World Architecture 2024年第1期8卷 63-75页

作者： Amallinaly GCárdenas Aguilar Peter Chung Alonso Alicia Cuevas muñiz Dora Correa fuentes Ignacio Barajas Avalos National Technological Institute of mexico Mexico CityMexico University of Colima Colima 28040Mexico

The objective of this study was to determine the degree of citizen participation in urban planning processes in the municipality of Comala,Colima,mexico to have a broader vision of the citizens and the environment in which they *** instrument was designed specifically to perform this study and the instrument was validated by calculating Cronbach’s *** results showed that citizens were highly involved in issues concerning their urban environment,and the main problems of the public spaces were also identified.

关键词： Citizen participation Planning Urban development program

Association between Helicobacter pylori infection,mismatch repair,HER2 and tumor-infiltrating lymphocytes in gastric cancer

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World Journal of Gastrointestinal Oncology 2024年第6期16卷 2487-2503页

作者： Carlos A Castaneda miluska Castillo Luis A Bernabe Joselyn Sanchez matteo Fassan Katherine Tello Ignacio Ivan Wistuba Ivan Chavez Passiuri Eloy Ruiz Juvenal Sanchez Fernando Barreda Daniel Valdivia Yaqueline Bazan milagros Abad-Licham Claudio mengoa Hugo fuentes Paola montenegro Ebert Poquioma Raul Alatrista Claudio J Flores Luis Taxa Faculty of Health Sciences Universidad Cientifica del SurLima 15038Peru GECO PERU Grupo de Estudios Clinicos Oncologicos del PeruLima 15038Peru Department of Research Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Faculty of Human medicine Universidad Ricardo PalmaLima 15039Peru Department of medicine Surgical Pathology&Cytopathology UnitUniversity of PaduaPadua 35121Italy Department of Translational molecular Pathology The University of Texas MD Anderson Cancer CenterHoustonTX 77030United States Department of Abdominal Surgery Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Department of Pathology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Department of medical Specialties Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Department of Pathology Instituto Regional de Enfermedades Neoplasicas del NorteTrujillo 13001Peru Faculty of Human medicine Universidad Privada Antenor OrregoTrujillo 13008Peru Department of Surgery Instituto Regional de Enfermedades Neoplasicas del SurArequipa 04002Peru Department of medical Oncology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Department of Epidemiology Instituto Nacional de Enfermedades NeoplasicasLima 15038Peru Unidad de Investigación Básica y Traslacional Oncosalud-AUNALima 15038Peru Faculty of medicine Universidad San Martin de PorresLima 15008Peru

BACKGROUND The influence of Helicobacter-pylori(***)infection and the characteristics of gastric cancer(GC)on tumor-infiltrating lymphocyte(TIL)levels has not been extensively *** of infiltrating-immune-cell subtypes as well as survival is necessary to obtain comprehensive *** To determine the rates of deficient mismatch-repair(dmmR),HER2-status and *** infection and their association with TIL levels in *** Samples from 503 resected GC tumors were included and TIL levels were evaluated following the international-TILs-working-group recommendations with assessment of the intratumoral(IT),stromal(ST)and invasive-border(IB)*** density of CD3,CD8 and CD163 immune cells,and dmmR and HER2-status were determined by immunohistochemistry(IHC).*** infection was evaluated by routine histology and quantitative PCR(qPCR)in a subset of *** dmmR was found in 34.4%,HER2+in 5%and ***-positive in 55.7%of *** IT-TIL was associated with grade-3(P=0.038),while ST-TIL with grade-1(PmmR was associated with high TIL levels in the ST(P=0.019)and IB(P=0.01)compartments,and STCD3(P=0.049)and ST-CD8(P=0.05)***2-was associated with high IT-CD8(P=0.009).*** was associated with high IT-TIL levels(P=0.009)when assessed by routine-histology,and with high TIL levels in the 3 compartments(P=0.002-0.047)and CD8 density in the IT and ST compartments(P=0.001)when assessed by qPCR.A longer overall survival was associated with low IT-CD163(P=0.003)and CD8/CD3(P=0.001 in IT and P=0.002 in ST)and high IT-CD3(P=0.021),ST-CD3(P=0.003)and CD3/CD163(P=0.002).CONCLUSION TIL levels were related to dmmR and *** CD8/CD3 and high CD163/CD3 were associated with lower recurrence and longer survival.

关键词： Lymphocytes macrophages Gastric cancer Helicobacter pylori HER2 mismatch repair

超高分辨光子计数CT评估冠状动脉支架通畅性：与有创法冠状动脉造影的对照研究

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国际医学放射学杂志 2024年第5期 619-620页

作者： m.T.Hagar m.Soschynski R.Saffar m.F.molina-fuentes J.Weiss A.Rau 苗彦许振华

目的与有创冠状动脉造影（ICA）对照，评价超高分辨光子计数CT血管成像（UHR PCD-CTA）检测冠状动脉支架通畅性的准确度。方法前瞻性纳入2022年8月—2023

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The Iberian Roma Population Variant Server(IRPVS)

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Journal of Genetics and Genomics 2024年第7期51卷 769-773页

作者： Fabiola mavillard Javier Perez-Florido Francisco m.Ortuño Amador Valladares miren L.Álvarez-Villegas Gema Roldán Rosario Carmona manuel Soriano Santiago Susarte Pilar fuentes Daniel López-López Ana maría Nuñez-Negrillo Alejandra Carvajal Yolanda morgado Daniel Arteaga Rosa Ufano Pablo mir Juan F.Gamella Joaquín Dopazo Carmen Paradas macarena Cabrera-Serrano Instituto de Biomedicina de Sevilla(IBiS) Hospital Universitario Virgen del Rocío/CSIC/Universidad de SevillaSevillaSpain Centro Investigación Biomédica en Red Enfermedades Neurodegenerativas(CIBERNED) Instituto de Salud CarlosⅢSevillaSpain Plataforma Andaluza de medicina Computacional Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevillaSpain Grupo de medicina computacional de sistemas Instituto de Biomedicina de Sevilla(IBiS)Hospital Virgen del RocíoSevillaSpain Nodo de Genómica Funcional (INB-ELIXIR-es)Fundación Progreso y Salud(FPS)Hospital Virgen del RocíoSevilla 41013Spain Bioinformática en Enfermedades raras(BiER) Centro de Investigación Biomédica en Red de Enfermedades Raras(CIBERER)Instituto de salud CarlosⅢSevillaSpain Departamento de Ingeniería de Computadores Automática y RobóticaUniversidad de GranadaGranadaSpain Servicio de Urgencias de Atención Primaria Distrito SevillaSevillaSpain Centro de Servicios Sociales Negociado de Servicios EspecializadosAyuntamiento de SevillaSevillaSpain Departamento de Enfermería Facultad de Ciencias de la SaludUniversidad de GranadaGranadaSpain Departamento de Neurología Hospital Virgen de las NievesGranadaSpain Departamento de Neurología Hospital Virgen de ValmeSevillaSpain Centro de Salud Utrera Sur SevillaSpain Centro de Salud Polígono Sur SevillaSpain Unidad de Trastornos del movimiento Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain Departamento de medicina Facultad de MedicinaUniversidad de SevillaSevilleSpain Departamento de Antropología Social Universidad de GranadaSpain Unidad Enfermedades Neuromusculares Servicio de Neurología y Neurofisiología ClínicaHospital Universitario Virgen del RocíoSevillaSpain

In recent years,the number of known disease genes has exponentially grown due to the widespread adoption of cost-effective massive parallel *** identify new disease variants,especially in monogenic disorders,a frequen... 详细信息

关键词： Server filtering massive

Cities and methods from Complexity Science

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Journal of Systems Science & Complexity 2016年第5期29卷 1177-1186页

作者： BALmACEDA Beatriz fuentes miguel CIDES Corpotraining Av. Providencia 2370 Santiago Chile Santa Fe Institute 1399 Hyde Park Road Santa Fe New Mexico 87501 USA IIF-Sadaf/CONICET Bulnes 642 Buenos Aires 1176 Argentina Facultad de Ingenieria y Tecnologla Universidad San Sebastidn Lota 2465 Santiago 7510157 Chile

The dynamics of human society is now been studying in the context of the artificial environment created by cities. In this work, the authors describe some of the formal methods used in complexity science to study urban systems. The authors discuss some of the important quantitative approaches on cities paying attention to some of the deepest controversies in present scientific *** authors will stress the importance of a transdisciplinary approach when studying this type of cooperative social environments.

关键词： Cities complexity environment.

New approaches for precise response evaluation in hepatocellular carcinoma

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World Journal of Gastroenterology 2014年第12期20卷 3059-3068页

作者： Koichi Hayano Jorge m fuentes-Orrego Dushyant V Sahani Division of Abdominal Imaging and Intervention Department of RadiologyMassachusetts General Hospital

With the increasing clinical use of cytostatic and novel biologic targeted agents,conventional morphologic tumor burden assessments,including World Health Organization criteria and Response Evaluation Criteria in Solid Tumors,are confronting limitations because of their difficulties in distinguishing viable tumor from necrotic or fibrotic ***,the investigation for reliable quantitative biomarkers of therapeutic response such as metabolic imaging or functional imaging has been *** this review,we will discuss the conventional and new approaches to assess tumor *** targeted therapy or locoregional therapies can induce biological changes much earlier than morphological changes,these functional tumor burden analyses are very ***,some of them have not gone thorough all steps for standardization and ***,these new techniques and criteria will play an important role in the cancer management,and provide each patient more tailored therapy.

关键词： Hepatocellular carcinoma World Health Organization criteria Response Evaluation Criteria in Solid Tumors European Association for the Study of Liver Computed tomography perfusion Dynamic contrast-enhanced-magnetic resonance imaging Diffusion-weighted imaging Positron emission tomography