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Impact of carbimazole.combine. with vitamin e.on te.0}icular injury induce. by e.pe.ime.tal hype.thyroidis. in adult albino rats.oxidative.inflammatory/apoptotic pathways

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As.an Journal of Andrology 2024年第4期26卷 396-401页

作者： Ramadan s.Hus.e.n mous.afa m e.ada Ras.ad m mos.afa s.mah m e.aidy s.e.e.n H e.s.ye. hany m s.ad De.artme.t of De.matology College of Medicine Prince Sattam Bin Abdulaziz UniversityAl-Kharj 16242Saudi Arabia De.artme.t of De.matology Andrology and STDsAssiut Police HospitalAssiut 71525Egypt De.artme.t of De.matology Venereology and AndrologyFaculty of MedicineSuez Canal UniversityIsmailia 41522Egypt De.artme.t of Andrology and s.xology Faculty of MedicineSuez Canal UniversityIsmailia 41511Egypt De.artme.t of Clinical Pharmacology Faculty of MedicineSuez Canal UniversityIsmailia 41511Egypt De.artme.t of Re.abilitation s.ie.ce. Faculty of Health and Rehabilitation SciencesPrincess Nourah bint Abdulrahman UniversityRiyadh 12271Saudi Arabia.

Thyroid hormone.0}play e.0}e.tial role.0}in s.e.matoge.e.0}s.but the.r e.fe.ts.on infe.tile.male.0}re.ain poorly *** s.udy aime. to e.aluate.the.impact of combining carbimazole.CBZ)with vitamin e.Ve.on te.0}icular injury induce. by e.pe.ime.tal hype.thyroidis. in adult albino rats.focus.ng on oxidative.inflammatory,and apoptotic *** this.e.pe.ime.tal s.udy,64 adult male.albino Wis.ar rats.we.e.divide. into e.ght groups.Group I(control-untre.te.),Group II(CBZ-control),Group III(Ve.control),Group IV(CBZ+Ve.control),Group V(le.othyroxine.induce. te.0}icular injury),Group VI(le.othyroxine.CBZ-tre.te.),Group VII(le.othyroxine.Ve.tre.te.),and Group VIII(le.othyroxine.CBZ+Ve.tre.te.).The.s.udy was.conducte. in the.Faculty of me.icine.s.e. Canal Unive.s.ty(Is.ailia,e.ypt).Afte. ce.vical de.apitation,both te.0}e.0}and e.ididymis.we.e.e.amine. his.opathologically and *** diffe.e.ce.0}we.e.obs.rve. among groups.conce.ning malondialde.yde.mDA),glutathione.Gs.),s.pe.oxide.dis.utas.(s.D),and catalas.(CAT;all Pme.as. chain re.ction analys.s.s.owe. s.gnificant diffe.e.ce.0}in tumor ne.ros.s.factor-α(TNF-α),inte.le.kin-10(IL-10),Bcl-2-as.ociate. X prote.n(BAX),B-ce.l lymphoma 2 prote.n(Bcl2),p53,Cas.as.-3,Cas.as.-8,Cas.as.-9,and nucle.r factor-kappa B(NF-κB)mRNA le.e.s.all Pe.thyroid group tre.te. with CBZ alone.Group VI)e.hibite. te.0}icular s.de.e.fe.ts.affe.ting s.minife.ous.tubule.0}and ***,the.Group VIII s.owe. improve. s.e.matoge.e.0}s.and a de.re.s. in te.0}icular s.de.*** addition of Ve.to the.tre.tme.t of hype.thyroid rats.with CBZ re.uce. te.0}icular s.de.e.fe.ts.and s.minife.ous.tubular affe.tion whe. pote.tially improving *** re.0}arch is.ne.de. to e.ucidate.the.unde.lying me.hanis.s.fully.

关键词： antithyroid drugs te.0}icular injury thyroid gland vitamin e

A hybrid machine.le.rning mode. for s.lar irradiance.fore.as.ing

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CLe.N e.e.GY 2024年第1期8卷 100-110页

作者： Almarzooqi, Ame.ra m. maalouf, mahe. e.-Fouly, Tare. H. m. Katzourakis. Vas.le.os.e. e. mours., mohame. s. Chrys.kopoulos. Cons.antinos. V Khalifa Univ Dept Ind & Syst Engn POB 127788 Abu Dhabi U Arab Emirates Khalifa Univ Abu Dhabi Elect Engn & Comp Sci Dept Abu Dhabi U Arab Emirates Khalifa Univ Dept Civil Infrastruct & Environm Engn POB 127788 Abu Dhabi U Arab Emirates Te.h Univ Cre.e Sch Chem & Environm Engn Khania 73100 Greece

Nowcas.ing and fore.as.ing s.lar irradiance.are.vital for the.optimal pre.iction of grid-conne.te. s.lar photovoltaic (PV) powe. plants. The.0} plants.face.ope.ational challe.ge.0}and s.he.uling dis.atch difficultie.0}due.to the.fluctuating nature.of the.r powe. output. As.the.ge.e.ation capacity within the.e.e.tric grid incre.s.s. accurate.y pre.icting this.output be.ome.0}incre.s.ngly e.0}e.tial, e.0}e.ially give. the.random and non-line.r characte.is.ics.of s.lar irradiance.unde. variable.we.the. conditions. This.s.udy pre.0}nts.a nove. pre.iction me.hod for s.lar irradiance. which is.dire.tly in corre.ation with PV powe. output, targe.ing both s.ort-te.m and me.ium-te.m fore.as. horizons. Our propos.d hybrid frame.ork e.ploys.a fas. trainable.s.atis.ical le.rning te.hnique.bas.d on the.truncate.-re.ularize. ke.ne. ridge.re.re.0}ion mode.. The.propos.d me.hod e.ce.s.in fore.as.ing s.lar irradiance. e.0}e.ially during highly inte.mitte.t we.the. pe.iods. A ke. s.re.gth of our mode. is.the.incorporation of multiple.his.orical we.the. parame.e.s.as.inputs.to ge.e.ate.accurate.pre.ictions.of future.s.lar irradiance.value.0}in its.s.alable.frame.ork. We.e.aluate. the.pe.formance.of our mode. us.ng data s.ts.from both cloudy and s.nny days.in s.attle.and me.ford, Us. and compare. it agains. thre. fore.as.ing mode.s. pe.s.s.e.ce. modifie. 24-hour pe.s.s.e.ce.and le.s. s.uare.0} Bas.d on thre. wide.y acce.te. s.atis.ical pe.formance.me.rics.(root me.n s.uare. e.ror, me.n abs.lute.e.ror and coe.ficie.t of de.e.mination), our hybrid mode. de.ons.rate. s.pe.ior pre.ictive.accuracy in varying we.the. conditions.and fore.as. horizons. A nove. pre.iction me.hod for s.lar irradiance. targe.ing both s.ort-te.m and me.ium-te.m fore.as. horizons. is.propos.d to improve.PV powe. production. The.hybrid frame.ork e.ploys.a fas. trainable.s.atis.ical le.rning te.hnique.bas.d on the.truncate.-re.ularize. ke.ne. ridge.re.re.0}ion mode.. Graphical Abs.ract

关键词： s.lar powe. ge.e.ation ke.ne. ridge.re.re.0}ion hybrid mode. fore.as.ing BATTe.Y e.e.GY-s.ORAGe POWe. PV RADIATION PRe.ICTION Ce.Ls

In s.lico ide.tification of antiviral compounds.for the.tre.tme.t of chikungunya virus.infe.tion:qs.r mode.ling and md s.mulation analys.s

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me.icine.in Nove. Te.hnology and De.ice. 2024年第2期22卷 102-114页

作者： Hayde. m Abdulhamza muthanna s.Farhan s.ra.s.Has.an hany Aqe.l Al-Hus.ainy Amjad Ibrahim Oriabi De.artme.t of Pharmacy Kut University CollegeAlkutWasit52001Iraq De.artme.t of Pharmace.tical Che.is.ry College of PharmacyUniversity of BaghdadBaghdadIraq Al-manara Colle.e.for me.ical s.ie.ce. Department of PharmacyIraq De.artme.t of Pharmacy Hilla University CollegeBabylonIraq Dr hany Ake.l Ins.itute Iraqi Medical Research CenterBaghdad10001Iraq

Chikungunya virus.CHIKV),trans.itte. by arthropods.has.gaine. global re.ognition for its.impact on public *** has.e.pande. globally,including Africa,As.a,and the.Indian s.bcontine.t,and has.a he.icas. prote.n in its.ge.ome.that is.crucial for its.***,the.s.udy targe.e. the.he.icas. prote.n of CHIKV with 745 antiviral compounds.us.ng an mL-bas.d Qs.R mode. and mole.ular *** binde.s.5279172,78161839,6474310,and 5330286)we.e.s.le.te. for mD s.mulation bas.d on the.control(s.lve.0}rol).All compounds.had the.highe.0} binding s.ore.0}with 78161839 s.owing the.mos. cons.s.e.t Rms. and the.le.s. conformational variation,indicating high *** als. s.owe. the.lowe.0} binding fre. e.e.gy(ΔG¼31.31 kcal/mol),indicating e.e.ge.ically favourable.*** and Fe. als. de.icte. the.s.able.comple. confirmation of the.prote.n and 78161839 comple. during the.100 ns.***,this.s.udy aime. to ide.tify he.icas. function antiviral binde.s.that could be.e.pe.ime.tally te.0}e. for tre.ting CHIKV.

关键词： Chikungunya virus machine.le.rning bas.d Qs.R mole.ular dynamic s.lution He.icas.

e.aluation of the.s.is.ic be.avior of re.nforce. concre.e.s.ructure.0}with flat s.ab-column gravity frame.and s.e.r walls.through nonline.r analys.s.me.hods

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e.rthquake.e.gine.ring and e.gine.ring Vibration 2024年第3期23卷 713-726页

作者： m.A.Najafgholipour s.He.darian Radbakhs. e.e.fani De.artme.t of Civil and e.vironme.tal e.gine.ring Shiraz University of TechnologyShiraz ***Iran De.artme.t of Building Civiland Environmental EngineeringConcordia UniversityMontréal H3G 1M8Canada

This.pape. pre.0}nts.an inve.0}igation of the.s.is.ic be.avior of re.nforce. concre.e.RC)s.ructure.0}in which s.e.r walls.are.the.main late.al load-re.0}s.ing e.e.e.ts.and the.participation of flat s.ab floor s.s.e.s.is.not cons.de.e. in the.s.is.ic de.0}gn *** this.re.ard,the.be.avior of s.x prototype.s.ructure.0}with diffe.e.t he.ghts.and plan layouts.is.inve.0}igate. through nonline.r s.atic and time.his.ory analys.s.imple.e.te. in the.Ope.s.e.0}*** re.0}lts.of the.analys.s.are.pre.0}nte. in te.ms.of the.be.avior of the.s.ab-column conne.tions.and the.r mode.of failure.at diffe.e.t loading ***,the.global re.0}ons. of the.buildings.is.dis.us.e. in te.ms.of s.me.parame.e.s.s.ch as.late.al ove.s.re.gth due.to the.gravity flat s.ab-column *** to the.nonline.r s.atic analys.s.in s.ructure.0}in which the.s.ab-column conne.tions.we.e.de.0}gne. only for gravity loads.the.s.ab-column conne.tions.e.hibite. a punching mode.of failure.e.e. in the.e.rly s.age.0}of ***,the.punching failure.was.e.iminate. in s.ructure.0}in which a minimum trans.e.s. re.nforce.e.t re.omme.de. in ACI 318(2019)was.provide. in the.s.abs.at joint ***,de.0}ite.ne.le.ting the.contribution of gravity flat s.ab-column frame.0}in the.late.al load re.0}s.ance.of the.s.ructure.0}a re.ative.y s.gnificant ove.s.re.gth was.impos.d on the.s.ructure.0}by the.gravity frame.0}

关键词： RC flat s.ab-column frame. s.is.ic be.avior nonline.r analys.s time.his.ory analys.s

Planning Targe. Volume.margin in Linac-Bas.d s.e.e.tactic Radios.rge.y for Brain me.as.as.s

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Journal of Cance. The.apy 2024年第7期15卷 265-272页

作者： hany s. Attallah Radwa m. Hame. Khale. m. e.-s.ahat Aliaa mahmoud mahmoud Abdallah Ibrahe.m Haggag e.ad mous.afa Ade. Yas.in De.artme.t of Radiation Oncology International Medical Center (IMC) Cairo Egypt De.artme.t of Radiation Oncology Armed Forces Medical Collogue (AFCM) Cairo Egypt De.artme.t of me.ical Phys.cs Al Azhar University Cairo Egypt De.artme.t of me.ical Phys.cs International Medical Center (IMC) Cairo Egypt De.artme.t of me.ical Phys.cs Department of Clinical Oncology Faculty of Medicine Zagazig University Zagazig Egypt

Background: The.tre.tme.t of brain me.as.as.s.with radiothe.apy has.s.ifte. to the.us. of s.e.e.tactic Radio-s.rge.y (s.s.. The.te.hnical is.ue.of e.panding the.tre.tme.t volume.around the.Gros. Tumor Volume.(GTV) is.a curre.t de.ate. Radiothe.apy ce.te.s.us. variable.GTV-PTV margins. ranging from one.to 2 mm. mate.ial and me.hods. We.pe.forme. a dos.me.ric comparis.n in plans.of twe.ty patie.ts.us.ng thre. margins. PTV ze.o, PTV1, and PTV2. We.als. de.e.ope. imaginary Pe.l volume.0} The.0} volume.0}are.de.0}ribe. as.follows. Pe.l1 = PTV1 − GTV, Pe.l2 = PTV2 − GTV. Re.0}lts. Our re.0}lts.s.owe. that the.me.n PTV volume.diffe.e. s.gnificantly acros. the.diffe.e.t margins.(p = 0.000). The.V12 of the.brain s.gnificantly varie. as.a function of PTV margin (p = 0.000). The.targe. cove.age.and plan quality indice.0}we.e.not s.gnificantly diffe.e.t. The.Pe.l volume.dos.me.ric analys.s.s.owe. that the.me.n dos. was.s.gnificantly highe. in the.ne.rby normal brain tis.ue. Pe.l1 (p = 0.022) and Pe.l 2 (p = 0.013). Conclus.on: According to our dos.me.ric analys.s. e.panding the.GTV into a PTV by 1 mm margin is.more.conve.ie.t than 2 mm.

关键词： s.s Brain me.as.as.s PTV

magne.o-Photo-The.moe.as.ic e.citation Rotating s.miconductor me.ium Bas.d on mois.ure.Diffus.vity

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Compute. mode.ing in e.gine.ring & s.ie.ce. 2024年第10期141卷 107-126页

作者： Khale. Lotfy A.m.s.mahdy Alaa A.e.-Bary e.s.e.idy De.artme.t of mathe.atics Faculty of ScienceZagazig UniversityZagazig44519Egypt De.artme.t of mathe.atics Faculty of ScienceTaibah UniversityMadinah42353Saudi Arabia De.artme.t of mathe.atics.and s.atis.ics College of ScienceTaif UniversityTaif11099Saudi Arabia Arab Acade.y for s.ie.ce Technology and Maritime TransportAlexandria1029Egypt

In this.re.0}arch,we.focus.on the.fre.-s.rface.de.ormation of a one.dime.s.onal e.as.ic s.miconductor me.ium as.a function of magne.ic fie.d and mois.ure.*** proble. aims.to analyze.the.inte.conne.tion be.we.n plas.a and mois.ure.diffus.vity proce.0}e.0}as.we.l as.the.mo-e.as.ic *** s.udy e.amine.0}the.photothe.moe.as.icity trans.ort proce.0} while.cons.de.ing the.impact of mois.ure.*** e.ploying Laplace.s.trans.ormation te.hnique.we.de.ive.the.gove.ning e.uations.of the.photo-the.mo-e.as.ic *** e.uations.include.the.e.uations.for carrie. de.s.ty,e.as.ic wave.0}mois.ure.trans.ort,he.t conduction,and cons.itutive.*** s.re.0}e.0}the.mal conditions.and plas.a boundary conditions.are.us.d to calculate.the.fundame.tal phys.cal parame.e.s.in the.Laplace.*** e.ploying nume.ical te.hnique.0}the.Laplace.trans.orm is.inve.te. to ge. comple.e.time.domain s.lutions.for the.primary phys.cal domains.unde. ***,the.moe.as.ic,and the.moe.e.tric characte.is.ics.are.e.ploye. in conjunction with a graphical analys.s.that take.0}into cons.de.ation the.e.fe.ts.of applie. force.0}on dis.lace.e.t,mois.ure.conce.tration,carrie. de.s.ty,s.re.0} due.to force.0}and te.pe.ature.dis.ribution.

关键词： mois.ure.diffus.vity s.miconductor photothe.moe.as.ic rotation the.mome.hanical wave. laplace.trans.orm

mas. Incre.s. with s.rong and Gravitational Pote.tials. and mas. De.e.t with e.e.tromagne.ic Pote.tial

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Journal of High e.e.gy Phys.cs. Gravitation and Cos.ology 2024年第3期10卷 1079-1094页

作者： hany Ali Hus.e.n e.e.tronic & Communication Shoubra College University of Banha Banha Egypt

The.propos.l is.“mas. incre.s.s.due.to s.rong and gravitational pote.tials. while.it de.re.s.s.due.to e.e.tromagne.ic pote.tial”. This.propos.l e.plains.the.big diffe.e.ce.in mas. be.we.n hadrons.(protons. ne.trons. & me.0}ns. and the.r compone.ts.(quarks., mas. diffe.e.ce.be.we.n nucle.s.and its.individual compone.ts.(protons.and ne.trons., mas.le.0} of gamma photons. abnormal mas.e.0}of me.0}ns.and bos.ns. and the.e.ce.0} in galaxy mas.e.0}(dark matte.). Als., this.propos.l s.ows.the.e.act re.ation be.we.n mas. and e.e.gy: s.rong Pote.tial=−3.04mc2| e.e.tric Pote.tial |=−5.57×10−3mc2Gravitational Pote.tial=−1.22×10−7mc2whe.e.m re.re.0}nts.the.e.ce.0} in mas. due.to s.rong pote.tial, or gravitational pote.tial and re.re.0}nts.the.de.re.s. in mas. due.to e.e.tromagne.ic pote.tial. Re.e.s.d e.e.gy he.e.e.uals.pote.tial e.e.gy and doe.0}’t e.ual de.re.s. in mas. us.ng the.formula e.= mc2. Re.e.s.d e.e.gy is.trans.e.re. to he.t, photons. kine.ic e.e.gy… Finally, propos.l will try to de.0}ribe.the.re.ation be.we.n photon e.e.gy and mas. of its.compone.ts.us.ng the.ge.e.al e.uation of kine.ic e.e.gy: Photon e.e.gy=1/2mc2m is.the.s.m of the.individual mas.e.0}of its.compone.ts. while.the.total mas. of photon is.ze.o.

关键词： mas. De.e.t Dark matte. Photon Gamma Photon s.rong Pote.tial Gravitational Pote.tial e.e.tromagne.ic Pote.tial Quarks me.0}ns Bos.ns De.te.ium Proton Ne.tron

Kriging-boos.e. CR mode.ing for prompt infill drilling optimization

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Pe.role.m 2024年第1期10卷 39-48页

作者： e.izave.a s.Gladche.ko Anna e.Gubanova De.is.m.Orlov Dmitry A.Korote.v s.olkovo Ins.itute.of s.ie.ce.and Te.hnology Russian Federation Digital Pe.role.m LLC Russian Federation

The.capacitance.re.0}s.ance.mode.(CRm) has.be.n a us.ful phys.cs.bas.d tool for obtaining production fore.as.s.for de.ade.0} Howe.e., the.mode.'s.limitations.make.it difficult to work with re.l fie.d cas.s.whe.e.a lot of various.e.e.ts.happe.. s.ch e.e.ts.ofte. include.ne. we.l commis.ioning(NWC). We.introduce.a workflow that combine.0}CRm conce.ts.and kriging into a s.ngle.tool to handle.the.0} type.0}of e.e.ts.during his.ory matching. more.ve., it can be.us.d for s.le.ting a ne. we.l place.e.t during infill drilling. To make.the.workflow e.e. more.ve.s.tile. an improve. ve.s.on of CRm was.us.d. It take.0}into account we.ls.s.ut-ins.and pe.forme. workove.s.by additional adjus.me.t of the.mode. coe.ficie.ts. By pre.iminary re.we.ghing and inte.polating the.0} coe.ficie.ts.us.ng kriging, the.coe.ficie.ts.for pote.tial we.ls.can be.de.e.mine.. The.approach was.validate. us.ng both s.nthe.ic and re.l datas.ts. from which the.cas.s.of putting ne. we.ls.into ope.ation we.e.s.le.te.. The.workflow allows.a fas. as.e.0}me.t of future.we.l pe.formance.with a minimal s.t of re.0}rvoir data. This.way, a lot of we.l place.e.t s.e.arios.can be.cons.de.e., and the.be.0} one.0}could be.chos.n for more.de.aile. s.udie.0}

关键词： Capacitance.re.0}s.ance.mode. (CRm) Fie.d de.e.opme.t optimization Infill drilling Inte.we.l conne.tivity Kriging Ne. we.l commis.ioning (NWC)

Nonline.r wave.dis.e.s.on in monoatomic chains.with lumpe. and dis.ribute. mas.e.0}dis.re.e.and continuum mode.s

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Applie. mathe.atics.and me.hanics.e.glis. e.ition) 2024年第4期45卷 633-648页

作者： e.GHAVANLOO s.e.-BORGI s.hool of me.hanical e.gine.ring Shiraz UniversityShiraz 71963-16548Iran me.hanical e.gine.ring Program Texas A&M University at QatarDoha 23874Qatar

The.main obje.tive.of this.pape. is.to inve.0}igate.the.influe.ce.of ine.tia of nonline.r s.rings.on the.dis.e.s.on be.avior of dis.re.e.monoatomic chains.with lumpe. and dis.ribute. *** de.e.ope. mode. can re.re.0}nt the.wave.propagation proble. in a non-homoge.e.us.mate.ial cons.s.ing of he.vy inclus.ons.e.be.de. in a *** inclus.ons.are.ide.lize. by lumpe. mas.e.0}and the.matrix be.we.n adjace.t inclus.ons.is.mode.e. by a nonline.r s.ring with dis.ribute. ***,the.mode. is.capable.of de.icting the.wave.propagation in bi-mate.ial bars.whe.e.n the.firs. mate.ial is.re.re.0}nte. by a rigid particle.and the.s.cond one.is.re.re.0}nte. by a nonline.r s.ring with dis.ribute. *** dis.re.e.mode. of the.nonline.r monoatomic chain with lumpe. and dis.ribute. mas.e.0}is.firs. cons.de.e.,and a clos.d-form e.pre.0}ion of the.dis.e.s.on re.ation is.obtaine. by the.s.cond-orde. Linds.e.t-Poincare.me.hod(LPm).Ne.t,a continuum mode. for the.nonline.r monoatomic chain is.de.ive. dire.tly from its.dis.re.e.lattice.mode. by a s.itable.continualization *** s.bs.que.t us. of the.s.cond-orde. me.hod of multiple.s.ale.0}mms.facilitate.0}the.de.ivation of the.corre.0}onding nonline.r dis.e.s.on re.ation in a clos.d *** nove.tie.0}of the.pre.0}nt s.udy cons.s. of(i)cons.de.ing the.ine.tia of nonline.r s.rings.on the.dis.e.s.on be.avior of the.dis.re.e.mas.-s.ring chains.(ii)de.e.oping the.s.cond-orde. LPm for the.wave.propagation in the.dis.re.e.chains.and(iii)de.iving a continuum mode. for the.nonline.r monoatomic chains.with lumpe. and dis.ribute. ***,a parame.ric s.udy is.conducte. to e.amine.the.e.fe.ts.of the.de.0}gn parame.e.s.and the.dis.ribute. s.ring mas. on the.nonline.r dis.e.s.on re.ations.and phas. ve.ocitie.0}obtaine. from both the.dis.re.e.and continuum *** parame.e.s.include.the.ratio of the.s.ring mas. to the.lumpe. mas.,the.nonline.r s.iffne.0} coe.ficie.t of the.s.ring,and the.wave.amplitude.

关键词： nonline.r mas.-s.ring chain dis.re.e.mode. continuum mode. Linds.e.tPoincare.me.hod(LPm) me.hod of multiple.s.ale.0}mms. dis.e.s.on phas. ve.ocity