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Changes in Calcareous Nannofossil Assemblages and paleoenvironmental Interpretation of the Early miocene Lice Formation, Kahramanmara? Basin, Turkey, East mediterranean

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Acta Geologica Sinica(English Edition) 2024年第4期98卷 1021-1034页

作者： Caner KAYAÖzEr muazez Esra OrHAN Uğur TEmİz Yozgat Bozok University DivanlıRoadYozgat 66900Turkey

This study investigated the calcareous nannofossil assemblages in detail from the early miocene aged Lice Formation outcropping in the Kahramanmara? basin. The biostratigraphy of calcareous nannofossils was outlined and paleoenvironmental features determined. In 81 samples taken from three measured sections in the region, 17 calcareous nannofossil genus and 48 nannofossil species were identified. These calcareous nannofossil genus and species identified the Lice Formation as being in the CNm4 nannofossil biozone. The abundance and diversity of early miocene calcareous nannofossil species varied in the measured sections, with the samples generally moderate-poor, apart from a few samples. The relative abundance of individuals of Cyclicargolithus floridanus, Coccolithus pelagicus, reticulofenestra hagii and Sphenolithus moriformis species, with paleoecological importance identified in the study region, indicate that in early miocene times, the basin in which the Lice Formation deposited was meso-eutrophic with excess nutrient input, temperate and generally stable shallow marine conditions.

关键词： paleoecology nannofossil Burdigalian East mediterranean

Transcriptional reprogramming during human osteoclast differentiation identifies regulators of osteoclast activity

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Bone research 2024年第1期12卷 180-198页

作者： morten S.Hansen Kaja madsen maria price Kent Søe Yasunori Omata mario m.zaiss Caroline m.Gorvin morten Frost Alexander rauch molecular Endocrinology Laboratory(KmEB) Department of EndocrinologyOdense University HospitalDK-5000 Odense CDenmark Department of Clinical research Faculty of Health SciencesUniversity of Southern DenmarkDK-5000 Odense CDenmark Clinical Cell Biology Pathology Research UnitDepartment of Clinical ResearchUniversity of Southern DenmarkDK-5000 Odense CDenmark Institute of metabolism and Systems research(ImSr)and Centre for Diabetes Endocrinology and Metabolism(CEDAM)University of BirminghamBirmingham B152TTUK Centre for membrane proteins and receptors(COmpArE) Universities of Birmingham and NottinghamBirmingham B152TTUK Department of molecular medicine University of Southern DenmarkDK-5000 Odense CDenmark Department of Orthopedic Surgery Faculty of MedicineThe University of TokyoTokyo 113-8655Japan Department of Internal medicine 3 Rheumatology and ImmunologyFriedrich-Alexander-University Erlangen-Nürnberg(FAU)and Universitätsklinikum ErlangenD-91054 ErlangenGermany Deutsches zentrum Immuntherapie(DzI) Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum ErlangenD-91054 ErlangenGermany Steno Diabetes Center Odense Odense University HospitalDK-5000 Odense CDenmark

Enhanced osteoclastogenesis and osteoclast activity contribute to the development of osteoporosis,which is characterized by increased bone resorption and inadequate bone *** novel antiosteoporotic therapeutics are needed,understanding the genetic regulation of human osteoclastogenesis could help identify potential treatment *** study aimed to provide an overview of transcriptional reprogramming during human osteoclast *** were differentiated from CD14+monocytes from eight female *** sequencing during differentiation revealed 8980 differentially expressed genes grouped into eight temporal patterns conserved across *** patterns revealed distinct molecular functions associated with postmenopausal osteoporosis susceptibility genes based on rNA from iliac crest biopsies and bone mineral density *** analyses revealed mutual dependencies between temporal expression patterns and provided insight into subtype-specific transcriptional *** donor-specific expression patterns revealed genes at the monocyte stage,such as filamin B(FLNB)and oxidized low-density lipoprotein receptor 1(OLr1,encoding LOX-1),that are predictive of the resorptive activity of mature *** expression of differentially expressed G-protein coupled receptors was strong during osteoclast differentiation,and these receptors are associated with bone mineral density SNps,suggesting that they play a pivotal role in osteoclast differentiation and *** regulatory effects of three differentially expressed G-protein coupled receptors were exemplified by in vitro pharmacological modulation of complement 5 A receptor 1(C5Ar1),somatostatin receptor 2(SSTr2),and free fatty acid receptor 4(FFAr4/Gpr120).Activating C5Ar1 enhanced osteoclast formation,while activating SSTr2 decreased the resorptive activity of mature osteoclasts,and activating FFAr4 decreased both the number and resorptive activity of mature *** conclus

关键词： osteoclast programming identif

Determination of the number ofψ(3686)events taken at BESⅢ

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Chinese physics C 2024年第9期48卷 8-20页

作者： m.Ablikim m.N.Achasov p.Adlarson O.Afedulidis X.C.Ai r.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-r.Bao V.Batozskaya K.Begzsuren N.Berger m.Berlowski m.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko r.A.Briere A.Brueggemann H.Cai X.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang G.r.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen H.Y.Chen m.L.Chen S.J.Chen S.L.Chen S.m.Chen T.Chen X.r.Chen X.T.Chen Y.B.Chen Y.Q.Chen z.J.Chen z.Y.Chen S.K.Choi G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.p.Dai A.Dbeyssi r.E.de Boer D.Dedovich C.Q.Deng z.Y.Deng A.Denig I.Denysenko m.Destefanis F.De mori B.Ding X.X.Ding Y.Ding Y.Ding J.Dong L.Y.Dong m.Y.Dong X.Dong m.C.Du S.X.Du Y.Y.Duan z.H.Duan p.Egorov Y.H.Fan J.Fang J.Fang S.S.Fang W.X.Fang Y.Fang Y.Q.Fang r.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.T.Feng m.Fritsch C.D.Fu J.L.Fu Y.W.Fu H.Gao X.B.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia L.Ge p.T.Ge z.W.Ge C.Geng E.m.Gersabeck A.Gilman K.Goetzen L.Gong W.X.Gong W.Gradl S.Gramigna m.Greco m.H.Gu Y.T.Gu C.Y.Guan z.L.Guan A.Q.Guo L.B.Guo m.J.Guo r.p.Guo Y.p.Guo A.Guskov J.Gutierrez K.L.Han T.T.Han F.Hanisch X.Q.Hao F.A.Harris K.K.He K.L.He F.H.Heinsius C.H.Heinz Y.K.Heng C.Herold T.Holtmann p.C.Hong G.Y.Hou X.T.Hou Y.r.Hou z.L.Hou B.Y.Hu H.m.Hu J.F.Hu S.L.Hu T.Hu Y.Hu G.S.Huang K.X.Huang L.Q.Huang X.T.Huang Y.p.Huang T.Hussain F.Hölzken N.Hüsken N.in der Wiesche J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.p.Ji W.Ji X.B.Ji X.L.Ji Y.Y.Ji X.Q.Jia z.K.Jia D.Jiang H.B.Jiang p.C.Jiang S.S.Jiang T.J.Jiang X.S.Jiang Y.Jiang J.B.Jiao J.K.Jiao z.Jiao S.Jin Y.Jin m.Q.Jing X.m.Jing T.Johansson S.Kabana N.Kalantar-Nayestanaki X.L.Kang X.S.Kang m.Kavatsyuk B.C.Ke V.Khachatryan A.Khoukaz r.Kiuchi O.B.Kolcu B.Kopf m.Kuessner X.Kui N.Kumar A.Kupsc W.Kühn J.J.Lane p.Larin L.Lavezzi T.T.Lei z.H.Lei m.Lellmann T.Lenz C.Li C.Li C.H.Li Cheng Li D.m.Li F.Li G.Li H.B.Li H.J.Li H.N.Li Hui Li J.r.Li J.S.Li Ke Li L.J.Li L.K.Li Lei Li m.H.Li p.r.Li Q.m.Li Q.X.Li r.Li S.X.Li T.Li W.D.Li W.G.Li X.Li X.H.Li X.L.Li X.z.Li Xi Institute of High Energy physics Beijing 100049China Beihang University Beijing 100191China Bochum ruhr-University D-44780BochumGermany Budker Institute of Nuclear physics SB rAS(BINp) Novosibirsk 630090Russia Carnegie mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COmSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion research GmbH D-64291DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute mainz Staudinger Weg 18D-55099MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati (A)INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly(B)INFN Sezione di PerugiaI-06100PerugiaItaly(C)University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara (A)INFN Sezione di FerraraI-44122FerraraItaly(B)University of FerraraI-44122FerraraItaly Inner mongolia University Hohhot 010021China Institute of modern physics Lanzhou 730000China Institute of physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de Alta Investigación Universidad de TarapacáCasilla 7DArica 1000000Chile Jilin University Changchun 130012China Joha

The number ofψ(3686)events collected by the BESⅢdetector during the 2021 run period is determined to be(2259.3±11.1)×10~6 by counting inclusiveψ(3686)hadronic *** uncertainty is systematic and the statistical uncertainty is ***,the numbers ofψ(3686)events collected during the 2009 and 2012run periods are updated to be(107.7±0.6)×10~6 and(345.4±2.6)×10~6,*** numbers are consistent with the previous measurements within one standard *** total number ofψ(3686)events in the three data samples is(2712.4±14.3)×10~6.

关键词： ψ(3686) inclusive process Hadronic events BESⅢdetector

Granger causal representation learning for groups of time series

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Science China(Information Sciences) 2024年第5期67卷 56-68页

作者： ruichu CAI Yunjin WU Xiaokai HUANG Wei CHEN Tom z.J.FU zhifeng HAO School of Computer Science Guangdong University of Technology peng Cheng Laboratory College of Science Shantou University

Discovering causality from multivariate time series is an important but challenging *** existing methods focus on estimating the Granger causal structures among multivariate time series,while ignoring the prior knowledge of these time series, e.g., the group of the time series. Focusing on discovering the Granger causal structures among groups of time series, we propose a Granger causal representation learning method to solve this problem. First, we use the multiset canonical correlation analysis method to learn the Granger causal representation of each group of time series. Then, we model the Granger causal relationships among the learned Granger causal representations using a recurrent neural network with temporal information. Finally, we formulate the above two stages into one unified optimization problem, which is efficiently solved using the augmented Lagrangian method. We conduct extensive experiments on synthetic and real-world datasets to validate the correctness and effectiveness of the proposed method.

关键词： Granger causal discovery Granger causal representation learning time series data recurrent neural network multiset canonical correlation analysis

A multi-sensor appiproach to calving detection

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Information processing in Agriculture 2024年第1期11卷 45-64页

作者： Anita z.Chang David L.Swain mark G.Trotter Institute for Future Farming Systems School of HealthMedicaland Applied SciencesCentral Queensland UniversityRockhamptonQueensland 4700Australia

The advent of remote livestock monitoring systems provides numerous possibilities for improving on-farm productivity,efficiency,and *** potential application for these systems is for the detection of calving *** study describes the integration of data from multiple sensor sources,including accelerometers,global navigation satellite systems(GNsS),an accelerometer-derived rumination algorithm,a walk-over-weigh unit,and a weather station for parturition detection using a support vector machine *** best performing model utilised data from GNsS,the ruminating algorithm,and weather stations to achieve 98.6%accuracy,with 88.5%sensitivity and 100%*** topranking features of this model were primarily GNSS *** study provides an overview as to how various sensor systems could be integrated on-farm to maximise calving detection for improved production and welfare outcomes.

关键词： Accelerometer GNSS GpS rumination Sensor WOW

Search for production of dark fermion candidates in association with heavy neutral gauge boson decaying to dimuon in proton-proton collisions at√s=8 TeV using CmS open data

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Chinese physics C 2024年第4期48卷 6-13页

作者： Y.mahmoud H.Abdallah m.T.Hussein S.Elgammal Centre for theoretical physics The British University in EgyptEgypt physics Department Faculty of ScienceCairo UniversityEgypt

In this study,we conducted a search for dark matter using a part of the data recorded by the CmS experiment during run-I of the LHC in 2012 with a center of mass energy of 8 TeV and an integrated luminosity of 11.6 fb−*** data were gathered from the CmS open *** matter,in the framework of the simplified model(mono-z′),can be produced from proton-proton collisions in association with a new hypothetical gauge boson,z′.Thus,the search was conducted in the dimuon plus large missing transverse momentum *** benchmark scenario of mono-z′,which is known as light vector,was used for interpreting the CmS open *** evidence of dark matter was observed,and exclusion limits were set on the masses of dark matter and z′at 95%confidence level.

关键词： dark matter large hadron collider CmS open data search for new physics dark fermion

Structural basis for polyuridine tract recognition by SArS-CoV-2 Nsp15

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protein & Cell 2024年第7期15卷 547-552页

作者： Fumiaki Ito Hanjing Yang z.Hong zhou Xiaojiang S.Chen molecular and Computational Biology Department of Biological SciencesUniversity of Southern CaliforniaLos AngelesCA 90089United States Department of microbiology Immunology and Molecular GeneticsUniversity of CaliforniaLos AngelesCA 90095United States California NanoSystems Institute University of CaliforniaLos AngelesCA90095United States Genetic Molecular and Cellular Biology ProgramKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90089United States Norris Comprehensive Cancer Center University of Southern CaliforniaLos AngelesCA 90089United States Center of Excellence in NanoBiophysics University of Southern CaliforniaLos AngelesCA 90089United States

Dear Editor,Coronaviruses have evolved a wide array of tactics to evade host antiviral *** host cells detect invading foreign nucleic acids including viral genome and viral replication intermediates,they activate interferon(IFN)signaling via cytoplasmic pattern recognition receptors(Kang et al.,2002;Kato et al.,2006).remarkable stealth activities exhibited by coronaviruses are facilitated by a series of non-structural proteins(Nsps),such as Nsp15(Deng and Baker,2018;Deng et al.,2019;Hackbart et al.,2020),which is a uridine-specific endoribonuclease that mediates evasion of host detection of viral double-stranded rNA(dsrNA)(Bhardwaj et al.,2004;Deng et al.,2017;Frazier et al.,2021;Ivanov et al.,2004).Nsp15 targets a polyuridine[poly(U)]tract on the coronavirus negative strand rNA(Hackbart et al.,2020).Nsp15 limits the abundance and length of poly(U)within the negative strand rNA 5ʹ-extension by trimming down the initially synthesized poly(U)lead sequence to the optimal length that can suppress dsrNA formation but still serves as a template for poly(A)tail of the positive strand genome of the coronaviruses(Hofmann and Brian,1991).

关键词： p15 interferon template

Survival and risk analysis of patients with COVID-19 in Iran

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Journal of Acute Disease 2024年第2期13卷 60-66页

作者： mottaghipoor F Heidari z Sami r memarzadeh H Saghaeiannejad Isfahani S Department of management and Health Information Technology Isfahan University of Medical SciencesIsfahanIran Department of Biostatistics and Epidemiology Isfahan University of Medical SciencesIsfahanIran Department of Internal medicine School of MedicineIsfahan University of Medical SciencesIsfahanIran Software Engineering Isfahan University of Medical SciencesIsfahanIran Health Information Technology research Center Isfahan University of Medical SciencesIsfahanIran

Objective:To evaluate the risk factors of death caused by COVID-19 in ***:This study was a retrospective cohort study from February 20,2020,to August 22,2022,in the hospitals in Isfahan,*** data were collected through a researcher-made *** determine the risk factors of the death,logistic regression and Cox regression models were *** each variable,the odds ratio and 95%confidence interval were also ***:1885 patients were *** age of deceased persons was significantly higher than that of the surviving *** risk of death for the age group above 60 years was about 14 times higher than that of people aged 19-35 years[95%CI:14.41(2.02-102.99),ppertension[95%CI:1.92(1.47-2.5),ppronic obstructive pulmonary disease[95%CI:1.92(1.47-2.50),pre also risk factors of ***:This study reveals that the mortality rate due to COVID-19 is associated with old age,longer hospitalization in the ICU,increased length of stay,and comorbidities of high blood pressure,diabetes,and chronic pulmonary disease.

关键词： Cause Death Survival COVID-19 risk factors Iran

Stability Investigation and Improvement for DC Cascade Systems with Simplified Impedance-based Stability Criterion

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CSEE Journal of power and Energy Systems 2024年第3期10卷 1044-1052页

作者： Junbin Fang zhikang Shuai Yang Li zhibing Wang Xiangyang Wu Xia Shen z.John Shen College of Electrical and Information Engineering Hunan UniversityChangsha 410082China renewable Energy Department of China Electric power research Institute Beijing 100192China Department of Electrical and Computer Engineering Illinois Institute of TechnologyChicagoIL 60616USA IEEE

In DC distributed power systems(DpSs),the complex impedance interactions possibly lead to DC bus voltage oscillation or *** previous research,the stability analysis of DpSs is implemented based on mathematical analysis in control *** specific mechanisms of the instability of the cascade system have not been intuitively *** this paper,the stability analysis of DpSs based on the traditional Nyquist criterion is simplified to the resonance analysis of the seriesconnected port impedance(z=r+jX)of source and load *** reveals that the essential reason for impedance instability of a DC cascade system is that the negative damping characteristic(rport the overall impedance amplifies the internal resonance source at reactance zero-crossing *** simplified stability criterion for DC cascade systems can be concluded as:in the negative damping frequency ranges(rre exists no zero-crossing point of the reactance component(i.e.,X=0).According to the proposed stability criterion,the oscillation modes of cascade systems are classified.A typical one is the internal impedance instability excited by the negative damping,and the other one is that the external disturbance amplified by negativity in a low stability ***,the impedance reshaping method for stability improvement of the system can be further *** validity of the simplified criterion is verified theoretically and experimentally by a positive damping reshaping method.

关键词： DC cascaded system,impedance model impedance reconstruction stability criterion