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molecular mechanisms controlling seed set in cereal crop species under stress and non-stress conditions

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Journal of Integrative Agriculture 2018年第5期17卷 965-974页

作者： lI Hui-yong Thomas lübberstedt Cereal Crops Research Institute Henan Academy of Agricultural Sciences Department of Agronomy Iowa State University

maximizing seed yield is the ultimate breeding goal in important cereal crop species. Seed set is a key developmental stage in the process of seed formation, which determines grain number, seed mass, and realized yield potential, and can be severely affected by abiotic and biotic stresses. However, seed set can also be substantially reduced by genetic factors even under optimal fertilization conditions. The underlying molecular genetic mechanisms are still obscure. In this review, we elucidate the process of seed set of cereal crop species in detail, including development of floral structures, formation of viable gametes, double fertilization, seed development, and abortion. We discuss how genetic and non-genetic factors affect seed set in different development stages. Finally, we will propose novel strategies to study genetic mechanisms controlling seed set and exploit genetic resources to improve seed set in cereal crop species.

关键词： maize seed set molecular mechanism

面向智慧新城的市政管线全周期数字孪生平台建设路径

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测绘通报 2024年第S1期 216-220页

作者：王光耀朱律王伟陈功亮汪旻琦上海市测绘院上海200063 自然资源部超大城市自然资源时空大数据分析应用重点实验室上海200063

针对上海市5个新城目前市政管线的建设现状和主要问题,基于数字孪生技术,本文提出并构建了面向智慧新城的市政管线全周期数字孪生平台,论述了平台建设的实施路径。在明晰地下管线规划管理机制的前提下,以建立数据标准体系和安全管控方... 详细信息

针对上海市5个新城目前市政管线的建设现状和主要问题,基于数字孪生技术,本文提出并构建了面向智慧新城的市政管线全周期数字孪生平台,论述了平台建设的实施路径。在明晰地下管线规划管理机制的前提下,以建立数据标准体系和安全管控方案为基础,基于建筑信息模型、物联感知、人工智能等技术,推动市政管线在规划、建设、运行、维护等全生命周期各环节与数字孪生技术的深度融合,对于新城市政管线集约高效建设和安全运行具有重要的推动作用。本文初步探讨了数字孪生技术在新城市政管线平台场景中的应用,能够为管线三维审批、应急保障、城市体检评估提供参考。

关键词：新城管线全生命周期物联感知数字孪生平台

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如何激励非家族员工的奉献精神?

家族企业 2024年第7期 20-21页

作者：莎朗·m·丹尼斯柴昱晟(译) 美国明尼苏达大学不详

创造有利于非家族员工“扎根”的职场环境,让他们的职业认同感与家族企业文化契合,将提升企业的创新能力和财务绩效。每家企业都希望广纳贤才,并想方设法让他们为企业长期效力。为此,营造并培育有利于提高生产力、帮助企业取得成功的工... 详细信息

创造有利于非家族员工“扎根”的职场环境,让他们的职业认同感与家族企业文化契合,将提升企业的创新能力和财务绩效。每家企业都希望广纳贤才,并想方设法让他们为企业长期效力。为此,营造并培育有利于提高生产力、帮助企业取得成功的工作环境至关重要。

关键词：职业认同感家族企业文化财务绩效非家族员工职场环境提高生产力广纳贤才奉献精神

In vitro antitumor activity of titanocene alanine complex and its interaction with nucleic acids

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Chinese Journal of Chemistry 1997年第3期15卷 225-233页

作者： Zhang, ZG Jin, l Yang, P SHANXI UNIV INST MOL SCITAIYUAN 030006SHANXIPEOPLES R CHINA

Titanocene alanine complex, Cp2Ti(O2CCH(CH3)NH3+Cl-)(2), has been found to have in vitro antitumor activity against Ehrlich ascites tumor cells. Study of the interaction between Cp2Ti(O2CCH(CH3)NH3+Cl-)(2) and DNA by UV-VIS spectra, fluorescence spectra, agarose gel electrophoresis reveals that Cp2Ti(O2CCH(CH3)NH3+Cl-)(2) forms a stable compound with DNA in molar ratio 1:1 and reduces the migration rate of ccc-DNA band and oc-DNA band. However, unlike cisplatin, the complex does not induce nicking of DNA even after a long incubation at a high ratio of the complex to DNA. The results suggest that titanocene-based antitumor agents have different mechanism of action from cisplatin-like antitumor agents.

关键词： titanocene alanine complex DNA antitumor

Relationships between Gene Structure and Genome Instability in Flowering Plants

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molecular Plant 2018年第3期11卷 407-413页

作者： Jeffrey l. Bennetzen Xuewen Wang State Key laboratory of Tea Plant Biology and Utilization/Key laboratory of Tea Biology and Processing Ministry of Agriculture Anhui Agricultural University HefeiAnhui 230036 People's Republic of China Department of Genetics University of Georgia Athens GA 30602 USA

Flowering plant （angiosperm） genomes are exceptional in their variability with respect to genome size, ploidy, chromosome number, gene content, and gene arrangement. Gene movement, although observed in some of the earliest plant genome comparisons, has been relatively underinvestigated. We present here- in a description of several interesting properties of plant gene and genome structure that are pertinent to the successful movement of a gene to a new location. These considerations lead us to propose a model that can explain the frequent success of plant gene mobility, namely that Small Insulated Genes move Around （SlGmAR）. The SIGmAR model is then compared with known processes for gene mobilization, and predic- tions of the SIGmAR model are formulated to encourage future experimentation. The overall results indicate that the frequent gene movement in angiosperm genomes is partly an outcome of the unusual properties of angiosperm genes, especially their small size and insulation from epigenetic silencing.

关键词： epigenetic silencing gene insulators gene movement illegitimate recombination inaccurate DNA break repair transposon mobilization

Eddy Kinetic Energy Study of the Snowstorm over Southern China in January 2008

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Advances in Atmospheric Sciences 2014年第4期31卷 972-984页

作者： ZUO Qunjie GAO Shouting l Daren laboratory of Cloud-Precipitation Physics and Severe Storms Institute of Atmospheric Physics Chinese Academy of Sciences Key laboratory of middle Atmosphere and Global Environment Observation Institute of Atmospheric Physics Chinese Academy of Sciences State Key laboratory of Severe Weather Chinese Academy of Meteorological Sciences

The energetics of the third stage of a snowstorm over China was analyzed using ECWmF *** analysis of the energy budget for the middle East trough and the western Pacific trough that developed toward China on 25-28 January 2008 showed the advection of the geopotential by the ageostrophic wind to be both a crucial source and the primary sink of the eddy kinetic energy centers associated with the *** magnitudes of the energy conversion terms,interaction kinetic energy conversion and baroclinic conversion,were too small to explain the development of the energy centers and the jet *** energy centers gained energy at their entrance regions via the convergence of the ageostrophic geopotential fluxes,and then lost energy at their exit regions by the same *** the entrance regions,the fluxes converged,increasing the geopotential gradient,which generated a stronger geostrophic wind and higher kinetic energy,resulting in an ascending motion in this *** the troughs moved to China,the ascending motion caused by the convergence of the fluxes at entrance region intensified the snowstorms over central and southern China.

关键词： eddy kinetic energy ageostrophic geopotential flux snowstorms jet streaks

Farnesoid X receptor,the bile acid sensing nuclear receptor,in liver regeneration

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Acta Pharmaceutica Sinica B 2015年第2期5卷 93-98页

作者： Guodong li Grace l.Guo Department of General Surgery the Fourth Hospital of Harbin Medical University Division of Biobank Research Department of General Surgery the Fourth Hospital of Harbin Medical University Department of Pharmacology and Toxicology Ernest Mario School of Pharmacy Rutgers the State University of New Jersey

The liver is unique in regenerative potential, which could recover the lost mass and function after injury from ischemia and resection. The underlying molecular mechanisms of liver regeneration have been extensively studied in the past using the partial hepatectomy(PH) model in rodents, where 2/3 PH is carried out by removing two lobes. The whole process of liver regeneration is complicated, orchestrated event involving a network of connected interactions, which still remain fully elusive. Bile acids(BAs) are ligands of farnesoid X receptor(FXR), a nuclear receptor of ligand-activated transcription factor. FXR has been shown to be highly involved in liver regeneration. BAs and FXR not only interact with each other but also regulate various downstream targets independently during liver regeneration. moreover, recent findings suggest that tissue-specific FXR also contributes to liver regeneration significantly. These novel findings suggest that FXR has much broader role than regulating BA, cholesterol, lipid and glucose metabolism. Therefore, these researches highlight FXR as an important pharmaceutical target for potentialuse of FXR ligands to regulate liver regeneration in clinic. This review focuses on the roles of BAs and FXR in liver regeneration and the current underlying molecular mechanisms which contribute to liver regeneration.

关键词： Farnesoid X receptor liver regeneration Bile acids Fibroblast growth factor 15 liver-intestine croass talk Transmembrane G protein coupled receptor 5

Contribution to sample failure probability plot and its solution by Kriging method

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Science China(Technological Sciences) 2013年第4期56卷 866-877页

作者： lI DaWei lü ZhenZhou ZHOU ChangCong School of Aeronautics Northwestern Ploytechnical University

To analyze the effect of the region of the model inputs on the model output,a novel concept about contribution to the sample failure probability plot(CSFP) is proposed based on the contribution to the sample mean plot(CSm) and the contribution to the sample variance plot(CSV).The CSFP can be used to analyze the effect of the region of the model inputs on the failure *** the definition of CSFP,its property and the differences between CSFP and CSV/CSm are *** proposed CSFP can not only provide the information about which input affects the failure probability mostly,but also identify the contribution of the regions of the input to the failure probability *** employing the Kriging model method on optimized sample points,a solution for CSFP is *** computational cost for solving CSFP is greatly decreased because of the efficiency of Kriging surrogate *** examples are used to illustrate the validity of the proposed CSFP and the applicability and feasibility of the Kriging surrogate method based solution for CSFP.

关键词： sample failure probability plot sensitivity analysis optimization sample points Kriging model region of the inputs

Alcohol-induced alterations of the hepatocyte cytoskeleton

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World Journal of Gastroenterology 2010年第11期16卷 1358-1365页

作者： Blythe D Shepard Pamela l Tuma Department of Biology The Catholic University of America

The hepatocyte cytoskeleton consists of three fi lamentous networks: microtubules, actin microfi laments and keratin intermediate filaments. Because of the abundance of the proteins that comprise each system and the central role each network plays in a variety of cellular processes, the three fi lament systems have been the focus of a host of studies aimed at understanding the progression of alcohol-induced liver injury. In this review, we will briefly discuss the hepatic organization of each cytoskeletal network and highlight some components of each system. We will also describe what is known about ethanol-induced changes in the dynamics and distributions of each cytoskeletal system and discuss what is known about changes in protein expression levels and post-translational modifi cations. Finally, we will describe the possible consequences of these cytoskeletal alterations on hepatocyte function and how they might contribute to the progression of liver disease.

关键词： Ethanol Hepatotoxicity Tubulin Actin Keratin