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肝移植病人肝细胞癌钆塞酸增强mRI特点

国际医学放射学杂志 2017年第5期 611-612页

作者： m.kim T.W.Kang W.K.Jeong Y.K.kim S.H.kim J.m.kim 耿立娜 Department of Radiology and Center for Imaging Science Samsung Medical CenterSungkyunkwan University School of Medicine

摘要目的比较已进行和未行肝移植(LT)手术病人肝细胞癌(HCC)mR特点,并评估上述特点与肝移植术后病人总生存率(OS)及肿瘤复发时间(TTR)之间的关系。方法比

关键词： mRI 肝细胞癌 HCC 肝移植

Comparison of macular changes according to the etiology of optic neuritis:a cross-sectional study

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 686-692页

作者： Yeji moon Sung-min kim Jae Ho Jung Department of Ophthalmology Asan Medical CenterUniversity of Ulsan College of MedicineSeoul 05505Republic of Korea Department of Neurology Seoul National University HospitalSeoul 03080Republic of Korea Department of Ophthalmology Seoul National University HospitalSeoul 03080Republic of Korea Department of Ophthalmology Seoul National University College of MedicineSeoul 03080Republic of Korea

AIm:To compare the macular structure including foveal thickness among patients with optic neuritis(ON)according to the etiology and to investigate the possible correlation between structural and visual outcomes mETHODS:In this retrospective cross-sectional study,the clinical data of patients with aquaporin-4 immunoglobulin G-related ON(AQP4 group,40 eyes),myelin oligodendrocyte glycoprotein IgG-related ON(mOG group,31 eyes),and multiple sclerosis-related ON(mS group,24 eyes)were *** retinal thickness of the foveal,parafoveal and perifoveal regions were *** acuity(VA),visual field index and mean deviation were measured as visual ***:The AQP4 group showed a significantly thinner fovea(226.4±13.4μm)relative to the mOG(236.8±14.0μm,P=0.015)and mS(238.9±14.3μm,P=0.007)*** thickness in the parafoveal area also was thinner in the AQP4 group,though the difference in perifoveal retinal thickness was not *** thickness was correlated with VA in the AQP4 group(coefficientρ=-0.418,P=0.014),but not in the mOG and mS groups(P=0.218 and P=0.138,respectively).There was no significant correlation between foveal thickness and visual field test in all three ***:The significant thinning in the fovea and parafoveal areas in the AQP4 group compared to the mOG and mS groups are ***,macular changes in AQP4-ON show a significant correlation with *** results provide the possibility that retinal structural damage could reflect functional damage in AQP4-ON,distinct from mOGON and mS-ON.

关键词： foveal thickness optic neuritis aquaporin-4 immunoglobulin myelin oligodendrocyte glycoprotein multiple sclerosis

Superplasticity of fine-grained mg-10Li alloy prepared by severe plastic deformation and understanding its deformation mechanisms

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Journal of magnesium and Alloys 2024年第1期12卷 316-331页

作者： H.T.Jeong S.W.Lee W.J.kim Department of materials Science and Engineering Hongik UniversityMapo-guSangsu-dong 72-1Seoul 121-791Republic of Korea

The superplastic behavior and associated deformation mechanisms of a fine-grained mg-10.1 Li-0.8Al-0.6Zn alloy(LAZ1011)with a grain size of 3.2μm,primarily composed of the BCCβphase and a small amount of the HCPαphase,were examined in a temperature range of 473 K to 623 *** microstructural refinement of this alloy was achieved by employing high-ratio differential speed *** best superplasticity was achieved at 523 K and at strain rates of 10^(-4)-5×10^(-4)s^(-1),where tensile elongations of 550±600%were *** the heating and holding stage of the tensile samples prior to tensile loading,a significant increase in grain size was observed at temperatures above 573 ***,it was important to consider this effect when analyzing and understanding the superplastic deformation behavior and *** the investigated strain rate range,the superplastic flow at low strain rates was governed by lattice diffusion-controlled grain boundary sliding,while at high strain rates,lattice diffusion-controlled dislocation climb creep was the rate-controlling deformation *** was concluded that solute drag creep is unlikely to *** the late stages of deformation at 523 K,it was observed that grain boundary sliding led to the agglomeration of theαphase,resulting in significant strain *** mechanism maps were constructed forβ-mg-Li alloys in the form of 2D and 3D formats as a function of strain rate,stress,temperature,and grain size,using the constitutive equations for various deformation mechanisms derived based on the data of the current tests.

关键词： magnesium-lithium alloy Superplasticity Severe plastic deformation Grain size Grain growth

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Advanced electrocatalysts with unusual active sites for electrochemical water splitting

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Infomat 2024年第1期6卷 65-82页

作者： Hainan Sun Xiaomin Xu Hyunseung kim Zongping Shao WooChul Jung Department of materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea WA School of mines:minerals Energy and Chemical Engineering(WASm-mECE) Curtin UniversityPerthWestern AustraliaAustralia

Electrochemical water splitting represents a promising technology for green hydrogen *** design advanced electrocatalysts,it is crucial to identify their active sites and interpret the relationship between their structures and *** extensively studied as electrocatalysts include noble-metal-based(e.g.,Ru,Ir,and Pt)and non-noble-metal-based(e.g.,3d transition metals)***,advancements in characterization techniques and theoretical calculations have revealed novel and unusual active *** present review highlights the latest achievements in the discovery and identification of various unconventional active sites for electrochemical water splitting,with a focus on state-of-the-art strategies for determining true active sites and establishing structure–activity ***,we discuss the remaining challenges and future perspectives for the development of next-generation electrocatalysts with unusual active *** presenting a fresh perspective on the unconventional reaction sites involved in electrochemical water splitting,this review aims to provide valuable guidance for the future study of electrocatalysts in industrial applications.

关键词： electrochemical water splitting hydrogen evolution reaction oxygen evolution reaction structure–activity relationship unusual active sites

Strong-field photoelectron holography in the subcycle limit

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Light(Science & Applications) 2024年第6期13卷 1032-1040页

作者： Tsendsuren Khurelbataro Jaewuk Heo ShaoGang Yu XuanYang Lai XiaoJun Liu Dong Eon kim Center for Attosecond Science and Technology Department of PhysicsPohang University of Science and TechnologyPohangGyeongbuk37673Korea max Planck POSTECH/KOREA Research Initiative PohangGyeongbuk37673Korea State Key Laboratory of magnetic Resonance and Atomic and molecular Physics Wuhan Institute of Physics and MathematicsInnovation Academy for Precision Measurement Science and TechnologyChinese Academy of Sciences430071WuhanChina Wuhan Institute of Quantum Technology 430206WuhanChina

Strong-field photoelectron holography is promising for the study of electron dynamics and structure in atoms and molecules,with superior spatiotemporal resolution compared to conventional electron and X-ray ***,the application of strong-field photoelectron holography has been hindered by inter-cycle interference from multicycle ***,we address this challenge by employing a near-single-cycle field to suppress the inter-cycle *** observed and separated two distinct holographic patterns for the first *** measurements allow us not only to identify the Gouy phase effect on electron wavepackets and holographic patterns but also to correctly extract the internuclear separation of the target molecule from the holographic *** work leads to a leap jump from theory to application in the field of strong-field photoelectron holography-based ultrafast imaging of molecular structures.

关键词： photoelectron holographic cycle

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碱改性铜锰尖晶石室温催化氧化空气中甲醛

Chinese Journal of Catalysis 2024年第5期60卷 337-350页

作者： Yongbiao Hua Kumar Vikrant Ki-Hyun kim Philippe m.Heynderickx Danil W.Boukhvalov 汉阳大学土木与环境工程系韩国首尔根特大学国际校区环境与能源研究中心催化与表征材料工程韩国仁川根特大学生物科学工程学院绿色化学与技术系比利时根特京林业大学理学院材料物理与化学研究所江苏南京210037 拉尔联邦大学物理与技术研究所俄罗斯叶卡捷琳堡

甲醛(FA)作为一种有致癌风险的有害污染物,在室内环境中普遍存在.为了高效去除甲醛,催化氧化技术成为了一种既经济又节能的选择,它不仅能降低材料成本(例如避免使用贵金属),也能在无光和室温的条件下进行.本文制备了一种成本效益高的碱... 详细信息

甲醛(FA)作为一种有致癌风险的有害污染物,在室内环境中普遍存在.为了高效去除甲醛,催化氧化技术成为了一种既经济又节能的选择,它不仅能降低材料成本(例如避免使用贵金属),也能在无光和室温的条件下进行.本文制备了一种成本效益高的碱改性锰酸铜尖晶石(Cumn^(2)O_(4))催化剂,并用于甲醛催化氧化反应中.实验结果表明,采用碱(1 mol L^(-1)氢氧化钾)改性的Cumn^(2)O_(4)(1-Cumn^(2)O_(4))作为催化剂,在室温条件下,当甲醛浓度为50 ppm,气体空速为4777 h^(-1)时,甲醛转化率(XFA)达到100%;此外,在甲醛转化率为10%时,其稳态反应速率达到了8.18×10^(-2) mmol g^(-1) h^(-1).原位漫反射红外傅立叶变换光谱结果表明,在催化剂的作用下,甲醛分子经过二氧亚甲基和甲酸酯中间体的转化,最终被氧化为水和二氧化碳.进一步结合密度泛函理论模拟发现,1-Cumn^(2)O_(4)具有较高的催化氧化甲醛性能,可归因于甲醛分子更牢固地吸附在1-Cumn^(2)O_(4)表面,甲醛吸附所需的能量较低,以及最终产物从催化剂表面脱附所需的能量也较低的综合效应.本研究为在无光和室温条件下,高效去除空气中甲醛提供了新型高效、成本效益高且无需贵金属的催化剂,从而为室内空气净化提供了新的科学见解.

关键词：甲醛碱修饰锰酸铜尖晶石催化氧化室内空气

Predicting moisture condensation risk on the radiant cooling floor of an office using integration of a genetic algorithm-back-propagation neural network with sensitivity analysis

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Energy and Built Environment 2024年第1期5卷 110-129页

作者： meng Su Jiying Liu moon Keun kim Xiaozhou Wu School of Thermal Engineering Shandong Jianzhu UniversityJinan 250101China Department of Civil Engineering and Energy Technology Oslo Metropolitan UniversityOslo N-0130Norway School of Civil Engineering Dalian University of TechnologyDalianChina

Pre-dehumidification time(τ_(pre))and pre-dehumidification energy consumption(E_(pre))play important roles in preventing the condensation of moisture on the floors of rooms that use a radiant floor cooling(RFC)***,there are few theoretical or experimental studies that focus on these two important *** this study,an artificial neural network(ANN)was used to predict condensation risk for the integration of RFC systems with mixed ventilation(mV),stratum ventilation(SV),and displacement ventilation(DV)systems.A genetic algorithm-back-propagation(GA-BP)neural network model was established to predict τ_(pre) and E_(pre).Both training data and validation data were obtained from tests in a computational fluid dynamics(CFD)*** results show that the established GA-BP model can predict τ_(pre) and E_(pre) *** coefficient of determination(R^(2))of τ_(pre) and of E_(pre) were,respectively,0.973 and *** an RFC system integrated with an mV,SV,or DV system,the lowest values of τ_(pre) and E_(pre) were with the DV system,23.1 s and 0.237 kWh,respectively,for a 67.5 m^(3) ***,the best pre-dehumidification effect was with integration of the DV and RFC *** study showed that an ANN-based method can be used for predictive control for condensation prevention in RFC *** also provides a novel and effective method by which to assess the pre-dehumidification control of radiant floor surfaces.

关键词： Condensation prevention Radiant floor cooling Ventilation system genetic algorithm BP neural network

Evolution of nonmetallic inclusions in 80-t 9CrmoCoB large-scale ingots during electroslag remelting process

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International Journal of minerals,metallurgy and materials 2024年第7期31卷 1525-1539页

作者： Shengchao Duan min Joo Lee Yao Su Wangzhong mu Dong Soo kim Joo Hyun Park School of mechanical and materials Engineering North China University of TechnologyBeijing 100144China Department of materials Science and Chemical Engineering Hanyang UniversityAnsan 15588Rep.of Korea Department of materials Science and Engineering KTH Royal Institute of TechnologyBrinellvägen 23Stockholm 10044Sweden Department of Engineering Science and mathematics Division of Materials ScienceLuleåUniversity of Technology97187 LuleåSweden Casting&Forging Business Unit Nuclear Business GroupDoosan EnerbilityChangwon 51711Rep.of Korea

In combination with theoretical calculations,experiments were conducted to investigate the evolution behavior of nonmetallic inclusions(NmIs)during the manufacture of large-scale heat-resistant steel ingots using 9CrmoCoB heat-resistant steel and CaF_(2)–CaO–Al_(2)O_(3)–SiO_(2)–B_(2)O_(3)electroslag remelting(ESR)-type slag in an 80-t industrial ESR *** main types of NmI in the consumable electrode comprised pure alumina,a multiphase oxide consisting of an Al_(2)O_(3)core and liquid CaO–Al_(2)O_(3)–SiO_(2)–mnO shell,and m_(23)C_(6)carbides with an mnS *** Al_(2)O_(3)and mnS inclusions had higher precipitation temperatures than the m_(23)C_(6)-type carbide under equilibrium and nonequilibrium solidification ***,inclusions can act as nucleation sites for carbide layer *** ESR process completely removed the liquid CaO–Al_(2)O_(3)–SiO_(2)–mnO oxide and mnS inclusion with a carbide shell,and only the Al_(2)O_(3)inclusions and Al_(2)O_(3)core with a carbide shell occupied the remelted *** m_(23)C_(6)-type carbides in steel were determined as Cr_(23)C_(6)based on the analysis of transmission electron microscopy *** substitution of Cr with W,Fe,or/and mo in the Cr_(23)C_(6)lattice caused slight changes in the lattice parameter of the Cr_(23)C_(6)***,Cr_(21.34)Fe_(1.66)C_(6),(Cr_(19)W_(4)C_(6),Cr_(18.4)mo_(4.6)C_(6),and Cr_(16)Fe_(5)mo_(2)C_(6)can match the fraction pattern of Cr_(23)C_(6)*** Al_(2)O_(3)inclusions in the remelted ingot formed due to the reduction of CaO,SiO_(2),and mnO components in the liquid *** increased Al content in liquid steel or the higher supersaturation degree of Al_(2)O_(3)precipitation in the remelted ingot than that in the electrode can be attributed to the evaporation of CaF_(2)and the increase in CaO content in the ESR-type slag.

关键词： nonmetallic inclusion heat-resistant steel electroslag remelting m_(23)C_(6) carbide mnS inclusion supersaturation degree

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High mobility group box 1 in the central nervous system:regeneration hidden beneath inflammation

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Neural Regeneration Research 2025年第1期20卷 107-115页

作者： Hanki kim Bum Jun kim Seungyon Koh Hyo Jin Cho Xuelian Jin Byung Gon kim Jun Young Choi Department of Brain Science Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Ajou University Graduate School of MedicineSuwonSouth Korea Department of Neurology Ajou University School of MedicineSuwonSouth Korea Department of Geriatrics The Affiliated Suqian First People’s Hospital of Nanjing Medical UniversitySuqianJiangsu ProvinceChina

High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and ***-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain *** drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system *** it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system *** this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory *** targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1.

关键词： central nervous system damage-associated molecular pattern ethyl pyruvate glycyrhizzin high mobility group box 1 inflammation neural stem cells neurodevelopment oligodendrocyte progenitor cells redox status regeneration

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