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Applying organic amendment enriches nutrient status of municipal solid waste compost and its application enhances tuber yield and nutrient concentrations of potato

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Waste Disposal and Sustainable Energy 2023年第4期5卷 439-450页

作者： marufa Sultana m.jahiruddin mohammad Golam Kibria md Hosenuzzaman md.Anwarul Abedin Department of Soil Science Faculty of AgricultureBangladesh Agricultural UniversityMymensingh2202Bangladesh Bangladesh Agricultural Research Institute JoydebpurBangladesh

Elevated price of chemical fertilizers and poor nutrient content in conventional organic sources such as municipal solid waste(mSW)compost necessitate the production of nutrient enriched compost which could serve as a potential alternative organic fertilizer *** studied three types of amended compost that were prepared by mixing 20%mustard oil cake(mOC)and 30%poultry manure(Pm)or cow dung or sugarcane press mud(SPm)with 50%mSW *** viride was inoculated into every type of *** rate of amended or unamended mSW compost application was 10 t ha^(−1).The use of different amendments improved the nutrient level of mSW compost,of which the N increment was remarkable,ranging from 1.14%N(unamended compost)to 2.9%–3.22%N depending on the types of amendment.A field experiment was conducted to evaluate performances of the amended mSW composts on the yield and nutrient content of potato(variety BARI Alu25).All compost treatments except the sole mSW compost treatment produced significantly higher tuber yields than the sole fertilizer *** press mud based mSW compost+fertilizer treatment produced the highest tuber yield of 31.6 t ha^(−1)(65%increase over 100%fertilizers and 57%increase over 100%compost treatment).The tuber N concentration varied from 0.128%to 0.594%,P from 0.018%to 0.035%,K from 0.213%to 0.313%and S from 0.020%to 0.053%,with the highest result recorded with press mud+fertilizer *** use of amended composts had residual effects on soil N,P,K and S ***,the treatment containing 50%fertilizer+50%compost mixture(mSW:mOC:SPm in a ratio of 5:2:3)performed the best followed by Pm amended *** is concluded that integrated use of 10 t ha^(−1) organic amended mSW compost with chemical fertilizers can ensure higher crop yield,nutrient content and sustained soil fertility in nutrient-deficient sub-tropical soil.

关键词： mustard oil cake mSW compost Potato Poultry manure Sugarcane press mud

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Effect of plastic mulch on crop yield and land degradation in south coastal saline soils of Bangladesh

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International Soil and Water Conservation Research 2018年第4期6卷 317-324页

作者： mohammad Asadul Haque muhammad jahiruddin Derek Clarke Department of Soil Science Patuakhali Science and Technology UniversityBangladesh Department of Soil Science Bangladesh Agricultural UniversityMymensinghBangladesh Department of Civil and Environmental Engineering University of SouthamptonUK

The experiment was conducted during dry season of 2016 and 2017 at farmer's field of Kalapara Upazila of Patuakhali district, Bangladesh to develop tools to reduce salinity impact in maize and to reduce salinity induced land degradation. There were five treatments in the experiment having three different color plastic mulch (blue, black and white) and rice straw mulch and a non mulch control (bare soil) treatment. The experiment was laid out in randomized complete block design with three replications. The treatments white, blue and black plastic film mulch, and rice straw much had 149%, 109%, 78% and 25% grain yield increase in 2016, and 173%, 117%, 99% and 47% in 2017 over control, respectively. The white plastic mulch treatment had 4 ℃ and 3.5 ℃ higher temperature over rice straw mulch treatment and 2.0 ℃ higher than the control treatment in 2016 and 2017, respectively. The black plastic mulch had 0.2 and 1.0 ℃, and rice straw mulch had 2.0 and 1.5 ℃ lower temperature than control in 2016 and 2017, respectively. Use of plastic mulch significantly reduces electrical conductivity of soil. In non-mulch treatment sulfur content was extremely high;plastic mulch rather helps to decrease the excess availability of sulfur. The overall results suggest that use of plastic mulch would be a suitable tool for enhancing maize production maintaining good soil health in saline soils.

关键词： Land degradation maize Plastic mulch Saline soil Straw mulch

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Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

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mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

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Neural Regeneration Research 2025年第3期20卷 805-807页

作者： Josém.Izquierdo Centro de Biología molecular Severo Ochoa(CBm) Consejo Superior de Investigaciones Científicas-Universidad Autónoma de Madrid(CSIC-UAM)MadridSpain

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of pre... 详细信息

关键词： Latin potential lasting

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Reduced tillage with residue retention improves soil labile carbon pools and carbon lability and management indices in a seven-year trial with wheat-mung bean-rice rotation

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Pedosphere 2022年第6期32卷 916-927页

作者： Rafeza BEGUm mohammad m.R.JAHANGIR mohammad jahiruddin mohammad Rafiqul ISLAm Shaikh m.BOKHTIAR Khandakar R.ISLAm Department of Soil Science Bangladesh Agricultural UniversityMymensingh 2202(Bangladesh) Soil Resource Development Institute Dhaka 1215(Bangladesh) South Asian Association for Regional Cooperation(SAARC)Agriculture Center Dhaka 1215(Bangladesh) The Ohio State University Columbus OH 43235(USA)

Soil total organic carbon(TOC)is a composite indicator of soil quality with implications for crop production and the regulation of soil ecosystem *** reports on the dynamics of TOC as a consequence of soil management practices in subtropical climatic conditions,where microbial carbon(C)loss is high,are very *** objective of our study was to evaluate the impact of seven years of continuous tillage and residue management on soil TOC dynamics(quantitative and qualitative)with respect to lability and stratification under an annual wheat-mung bean-rice cropping *** soil samples were collected at 0-15 and 15-30 cm depths from a three-replicate split-plot experiment with tillage treatment as the main plots and crop residue levels as the *** tillage treatments included conventional tillage(CT)and strip tillage(ST).Residue levels were high residue level(HR),30%of the plant height,and low residue level(LR),15%.In addition to TOC,soil samples were analyzed for particulate organic C(POC),permanganate oxidizable C(POXC),basal respiration(BR),specific maintenance respiration rate(qCO_(2)),microbial biomass C(mBC),potentially mineralizable C(PmC),and TOC lability and management *** ST treatment significantly increased the TOC and labile C pools at both depths compared with the CT treatment,with the effect being more pronounced in the surface *** HR treatment increased TOC and labile C pools compared with the LR *** ST+HR treatment showed significant increases in mBC,metabolic quotient(qR),C pool index(CPI),C lability index(CL_(I)),and C management index(CmI),indicating improved and efficient soil biological activities in such systems compared with the CT ***,the stratification values,a measure of soil quality improvement,for POC and mBC were>2,indicating improved soil quality in the ST+HR treatment compared with the CT *** ST+HR treatment not only significantly increased the contents o

关键词： basal respiration carbon management index carbon stratification particulate organic carbon permanganate oxidizable carbon total organic carbon

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Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson’s disease

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Neural Regeneration Research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira m.Holmström Henri J.Huttunen Herantis Pharma Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A major unmet need in the field of central nervous system diseases is disease-modifying *** for decades there have been various symptomatic treatments available to alleviate the symptoms of the disease,disease-modification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatment therapeutic

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Carbon mineralization in subtropical alluvial arable soils amended with sugarcane bagasse and rice husk biochars

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Pedosphere 2022年第3期32卷 475-486页

作者： mohammad Arifur RAHmAN mohammad Abdul KADER mohammad jahiruddin mohammad Rafiqul ISLAm Zakaria mohammad SOLAImAN Regional Agricultural Research Station(RARS) Bangladesh Agricultural Research Institute(BARI)Jamalpur 2000(Bangladesh) School of Agriculture GeographyEnvironmentOcean and Natural SciencesUniversity of South PacificApia 1343(Samoa) Department of Soil Science Bangladesh Agricultural University(BAU)Mymensingh 2202(Bangladesh) UWA School of Agriculture&Environment and the UWA Institute of Agriculture PerthWA 6009(Australia) School of Veterinary and Life Science Murdoch UniversityMurdochWA 6150(Australia)

Subtropical recent alluvial soils are low in organic carbon(C).Thus,increasing organic C is a major challenge to sustain soil *** amendment could be an option as biochar is a C-rich pyrolyzed material,which is slowly decomposed in *** investigated C mineralization(CO_(2)-C evolution)in two types of soils(recent and old alluvial soils)amended with two feedstocks(sugarcane bagasse and rice husk)(1%,weight/weight),as well as their biochars and aged biochars under a controlled environment(25±2℃)over 85 *** the recent alluvial soil(charland soil),the highest absolute cumulative CO_(2)-C evolution was observed in the sugarcane bagasse treatment(1140 mg CO_(2)-C kg^(-1)soil)followed by the rice husk treatment(1090 mg CO_(2)-C kg^(-1)soil);the lowest amount(150 mg CO_(2)-C kg^(-1)soil)was observed in the aged rice husk biochar ***,for the old alluvial soil(farmland soil),the highest absolute cumulative CO_(2)-C evolution(1290 mg CO_(2)-C kg^(-1)soil)was observed in the sugarcane bagasse treatment and then in the rice husk treatment(1270 mg CO_(2)-C kg^(-1)soil);the lowest amount(200 mg CO_(2)-C kg^(-1)soil)was in the aged rice husk biochar *** sugarcane bagasse and rice husk biochar treatments reduced absolute cumulative CO_(2)-C evolution by 10%and 36%,respectively,compared with unamended recent alluvial soil,and by 10%and 18%,respectively,compared with unamended old alluvial *** absolute and normalized C mineralization were similar between the sugarcane bagasse and rice husk treatments,between the biochar treatments,and between the aged biochar *** both soils,the feedstock treatments resulted in the highest cumulative CO_(2)-C evolution,followed by the biochar treatments and then the aged biochar *** absolute and normalized CO_(2)-C evolution and the mineralization rate constant of the stable C pool(K_(s))were lower in the recent alluvial soil compared with those in the old alluvial *** biochar

关键词： aged biochar biochar amendment charland CO_(2)emission CO_(2)-C evolution recent alluvial soil soil organic carboon soil organic matter

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Search for microglia-specific peptides:advances in the discovery toolbox

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Neural Regeneration Research 2025年第2期20卷 471-472页

作者： Ivan Sarabia Kyle m.Koss Department of Surgery University of ArizonaTucsonAZUSA

Uncontrolled and chronic inflammatory states in the central nervous system(CNS)are the hallmark of neurodegenerative pathology and every injury or stroke-related *** key mediators of these neuroinflammatory states are glial cells known as microglia,the resident immune cell at the core of the inflammatory event,and astroglia,which encapsulate inflammatory insults in proteoglycan-rich scar *** gliotic scar blocks significant portions of healthy axonal networking,preventing *** most neuroinflammation is exclusively based on the responses of said microglia,their phenotypes are suggested to follow those of macrophages;m1 and m2 are opposites of pro-and ***,microglial phenotypes have been identified to be on an inflammatory spectrum encompassing developmental,homeostatic,and reparative behaviors as opposed to their ability to affect devastating cell death cascades and scar tissue formation.

关键词： inflammation pathology death

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SBL-JP-0004: A promising dual inhibitor of JAK2 and PI3KCD against gastric cancer

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Oncology research 2025年第1期33卷 235-243页

作者： Hassan m Otifi Department of Pathology College of Medicine King Khalid University Abha 62521 Saudi Arabia.

Background:Gastric cancer (GC) remains a global health burden and is often characterized by heterogeneous molecular profiles and resistance to conventional therapies. The phosphoinositide 3-kinase and PI3K and Janus kinase (JAK) signal transducer and activator of transcription (JAK-STAT) pathways play pivotal roles in GC progression, making them attractive targets for therapeutic interventions.methods:This study applied a computational and molecular dynamics simulation approach to identify and characterize SBL-JP-0004 as a potential dual inhibitor of JAK2 and PI3KCD kinases. KATOIII and SNU-5 GC cells were used for evaluation.Results:SBL-JP-0004 exhibited a robust binding affinity for JAK2 and PI3KCD kinases, as evidenced by molecular docking scores and molecular dynamics simulations. Binding interactions and Gibbs binding free energy estimates confirmed stable and favorable interactions with target proteins. SBL-JP-0004 displayed an half-maximal inhibitory concentration (IC) value of 118.9 nm against JAK2 kinase and 200.9 nm against PI3KCD enzymes. SBL-JP-0004 exhibited potent inhibition of cell proliferation in KATOIII and SNU-5 cells, with half-maximal growth inhibitory concentration (GI) values of 250.8 and 516.3 nm, respectively. A significant elevation in the early phase apoptosis (28.53% in KATOIII cells and 26.85% in SNU-5 cells) and late phase apoptosis (17.37% in KATOIII cells and 10.05% in SNU-5 cells) were observed with SBL-JP-0004 treatment compared to 2.1% and 2.83% in their respective controls.Conclusion:The results highlight SBL-JP-0004 as a promising dual inhibitor targeting JAK2 and PI3KCD kinases for treating GC and warrant further preclinical and clinical investigations to validate its utility in clinical settings.

关键词： Dual inhibition Gastric cancer (GC) JAK2 molecular docking molecular dynamics simulation PI3KCD SBL-JP-0004

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Nonlinear forced vibration in a subcritical regime of a porous functionally graded pipe conveying fluid with a retaining clip

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 101-122页

作者： m.GHOLAmI m.EFTEKHARI Department of mechanical Engineering Shahid Bahonar University of Kerman

This study examines the nonlinear behaviors of a clamped-clamped porous pipe made of a functionally graded material(FGm) that conveys fluids and is equipped with a retaining clip, focusing on primary resonance and subcritical dynamics. The nonlinear governing equations for the FGm pipe are derived by the extended Hamilton's principle, and subsequently discretized through the application of the Galerkin *** direct method of multi-scales is then used to solve the derived equations. A thorough analysis of various parameters, including the clip stiffness, the power-law index, the porosity, and the clip location, is conducted to gain a comprehensive understanding of the system's nonlinear dynamics. Through the analysis of the first natural frequency, the study highlights the influence of the flow velocity and the clip stiffness, while the comparisons with metallic pipes emphasize the role of FGm composition. The examination of the forced response curves reveals saddle-node bifurcations and their dependence on parameters such as the detuning parameter and the power-law index, offering valuable insights into the system's nonlinear resonant behavior. Furthermore, the frequency-response curves illustrate the hardening nonlinearities influenced by factors such as the porosity and the clip stiffness, revealing nuanced effects on the system response and resonance characteristics. This comprehensive analysis enhances the understanding of nonlinear behaviors in FGm porous pipes with a retaining clip, providing key insights for practical engineering applications in system design and optimization.

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