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Immunity Genes and Susceptibility to Otitis media:A Com.rehensive review

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Journal of Genetics and Genomics 2014年第11期41卷 567-581页

作者： rahul mittal Giannina robalino robert Gerring Brandon Chan Denise Yan m'hamed Grati Xue-Zhong Liu Department of Otolaryngology University of Miami Miller School of Medicine Department of Human Genetics University of Miami Miller School of Medicine Department of Biochemistry University of Miami Miller School of Medicine

Otitis media （om） is a middle ear infection associated with inflammation and pain. This disease frequently afflicts humans and is the major cause of hearing loss worldwide. om continues to be one of the most challenging diseases in the medical field due to its diverse host targets and wide range of clinical manifestations. Substantial morbidity associated with om is further exacerbated by high frequency of recurrent infections leading to chronic suppurative otitis media （CSom）. Children have greater susceptibility to, and thus, suffer most frequently from om, which can cause significant deterioration in quality of life. Genetic factors have been demonstrated, in large part by twin and family studies, to be key determinants of om susceptibility. In this review, we summarize the current knowledge on immunity genes and selected variants that have been associated with predisposition to om. In particular, polymorphisms in innate immunity and cytokine genes have been strongly linked with the risk of developing om. Future studies employing state-of-the-art technologies, including next-generation sequencing （NGS）, will aid in the identification of novel genes associated with susceptibility to om. This, in turn, will open up avenues for identifying high-risk individuals and designing novel therapeutic strategies based on precise targeting of these genes.

关键词： Otitis media Genetics Innate immunity Cytokines

Long-term coastal erosion assessment along the coast of Karnataka,west coast of India

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International Journal of Sediment research 2019年第4期34卷 335-344页

作者： K.Sowmya m.Dhivya Sri Aparna S.Bhaskar K.S.Jayappa Department of marine Geology Mangalore University Department of Geography University of Madras Department of Civil Engineering SRM Institute of Science and Technology

Coastal areas are always under frequent threat from various natural processes and man-induced *** erosion is recognized as the permanent loss of land along the shoreline resulting in the transformation of the coast. The current study focuses on long-term coastal erosion analysis of the entire Karnataka coast using remote Sensing, Geographical Information System(GIS), Linear regression rate(Lrr), and End Point rate(EPr) techniques. Analysis of 26(1990 to 2016) years of erosion using Landsat images by the use of the Digital Shoreline Analysis System(DSAS) tool has been done. The results show a high erosion rate at Ullal during this period(Lrr-1.3 m/yr) and accretion at Devbagh(Lrr 3.2 m/yr). The southern Karnataka coast faces severe erosion especially at Ullal, where the settlement is high. At Thanirbhavi, mukka, Kota,and om Beaches erosion also is noticed. Both anthropogenic activities like ports, seawalls, breakwaters, *** natural processes like long shore drift, seasonal variation, etc. are factors affecting the shoreline change along the Karnataka coast.

关键词： Karnataka coast Landsat images Erosion Linear regression rate End Point rate

电接触加热速度对36HXTЮm8合金结构状态的影响

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金属材料研究 2000年第1期26卷 52-58页

作者： X.,om 刘佑华

弥散硬化合金进行淬火时采用民接触加热（通过电流），开辟了在保持过饱和固溶体的细日粒组织条件下，保证剩余相必须完全溶解，使合金的性能有重要改善的新途径，在通常的炉子加热条件下，这一点是难于达到的。这种淬火的优点，与超过... 详细信息

弥散硬化合金进行淬火时采用民接触加热（通过电流），开辟了在保持过饱和固溶体的细日粒组织条件下，保证剩余相必须完全溶解，使合金的性能有重要改善的新途径，在通常的炉子加热条件下，这一点是难于达到的。这种淬火的优点，与超过通常采用的淬火前加热温度合金短时间过热的可能性有关。因此，这种处理对含有难溶剩余相的合金来说，首先是有前任的。本文分析了淬火弥散硬化弹性合金３６ＨＸＴЮＭ８相成分和组成形成时。

关键词：镍合金结构状态电接触加热速度

Strength Developing in Clay-Andesite Brick

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materials Sciences and Applications 2016年第8期7卷 403-420页

作者： Víctor Julio García Alonso r. Zúñiga-Suárez Carmen omaira márquez Juan G. Pérez Francisco Fernández-martínez Francisco Hernández-Olivares Universidad Nacional de Chimborazo Riobamba Ecuador Universidad Técnica Particular de Loja Loja Ecuador Universidad de Los Andes Mérida Venezuela Universidad Politécnica de madrid Madrid Espana

The objective of this work was to develop a more and better understanding of the strength developing in clay-andesite fired brick. The purpose was to improve the quality of the clay bricks that are handmade in the southern region of Ecuador to make them suitable for more widespread use in the local construction industry. To achieve our goal, we first physically, chemically, and mechanically characterized the “clayey” and “sandy” materials used in the fabrication of handmade bricks in the region. Second, the optimal mixture (om): the optimal proportion between the amounts of “clayey” and “sandy” material was sought. Third, clay bricks were prepared using the om, baked at 950°C, and characterized. In addition, bricks produced by regional artisans were characterized, and the results were compared with the results obtained for the bricks prepared using the om. Our data reveal that the optimal mixture is 50% “clayey” material and 50% “sandy” material and that with this mixture, an average improvement in brick quality of 300% can be achieved;thus, the use of the om makes it possible to expand the use of these bricks in the local construction industry and enables an environmentally friendly production process by reducing the intensive exploitation of regional clay deposits. This improvement is achieved by virtue of the anorthite enrichment that occurs in the solid solution, which results from the evolution of andesine. The anorthite contributes to the formation of a stronger matrix among the different grains of the material. Conditions are favorable for this enrichment process to occur when “sandy” materials with high contents of andesite, which is common in Ecuadorian soils, are used.

关键词： Anorthite Andesine Andesite Component Fired Bricks Brazilian Test

Soil Formation of "Atlantic rankers" from NW Spain—A High resolution Aluminium and Iron Fractionation Study

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Pedosphere 2008年第4期18卷 441-453页

作者： J. KAAL m. COSTA-CASAIS C. FErrO-VZQUEZ X. PONTEVEDrA-PomBAL A. mArTINEZ-COrTIZAS Instituto de Estudios Galegos Padre Sarmiento Laboratorio de Arqueología del Paisaje (LAr) IEGPS-CSIC-XuGaRúa San Roque 2 15704 Santiago de Compostela (Spain). Departamento de Edafología y Química Agrícola Fac. Biología Universidad de Santiago (Spain)

Atlantic rankers belong to the group of ＂cryptopodzolic rankers＂, which are ubiquitous in the mountainous cool/temperate humid regions of Western Europe. The rankers of Galicia （NW Spain） formed by thousands of years of colluviation. The preponderance of Al-stabilised organic matter （om） masks the horizonation and polycyclic character （i.e., stratification） of these soils. Cryptopodzolic rankers are generally thought to be the outcome of podzolisation. This soil type is part of the recent discussion on how to classify soils developed from nonvolcanic parent material having andic properties. To better understand the formation processes of these soils, the Al and Fe fractionation of four typical Atlantic rankers were studied by selective dissolution in acid NH4-oxalate, Na-pyrophosphate and the chlorides of K, La and Cu. A high-resolution sampling approach allowed us to investigate the soils in greater detail than simply sampling by horizon. The rankers studied display a distribution of Fe- and AI-om complexes that is typical of cryptopodzolic soils. However, these organomineral associations were probably immobile due to the high Al saturation. We argue that the soils owe their characteristic chemical status to external factors rather than to translocation of organomineral associations： variations in AI-om concentrations could be linked to changes in weathering/leaching intensity and colluviation rates caused by anthropogenic disturbances or changes in regional climate regime.

关键词： Al fractionation colluviation cryptopodzolic soil podzolisation ranker

相位可控的氟钪纳米晶的合成及其上转换发光性能

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无机化学学报 2019年第6期35卷 947-954页

作者：丁玉洁金星刘倩钱桂香 Abdullah m.Asiri Hadi m.marwani 安徽工程大学生物与化学工程学院芜湖241000 Chemistry Department Faculty of ScienceKing Abdulaziz UniversityJeddah 21589Saudi Arabia

控制反应条件如表面活性剂的组成、加入量或反应时间,可以制得不同形态、相结构且具有上转换发光(UCL)的氟钪纳米晶(NCs)。改变表面活性剂油酸(OA)/油胺(om)的比例有利于晶体结构从立方相ScF3∶Yb,Er转变为具有上转换发光性能增强的正交... 详细信息

控制反应条件如表面活性剂的组成、加入量或反应时间,可以制得不同形态、相结构且具有上转换发光(UCL)的氟钪纳米晶(NCs)。改变表面活性剂油酸(OA)/油胺(om)的比例有利于晶体结构从立方相ScF3∶Yb,Er转变为具有上转换发光性能增强的正交相KSc2F7∶Yb,Er纳米晶,而纳米晶的形态会发生从小到大的转变。改变掺杂元素的种类及含量,在980nm光激发下,KSc2F7纳米晶的上转换发光可以从蓝色变到白色,再到主要发射紫色光。

关键词：上转换氟钪纳米晶相跃迁

稀释率对于活体外瘤胃发酵和微生物生长效率的影响

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动物营养学报 1999年第1期11卷 10-16页

作者：孟庆翔高仲元 m.S.Kerley r.L.Belyea 中国农业大学动物科技学院美国密苏里大学动物科学系

采用连续培养系统的４个发酵罐进行３次连续培养试验，研究瘤胃稀释率（ＤＲ，下同）对于瘤胃微生物发酵和微生物生长效率的影响。瘤胃稀释率为每小时发酵液流出量占发酵罐体积的０．０３和０．０６。试验日粮唯一由大豆皮组成。随着Ｄ... 详细信息

采用连续培养系统的４个发酵罐进行３次连续培养试验，研究瘤胃稀释率（ＤＲ，下同）对于瘤胃微生物发酵和微生物生长效率的影响。瘤胃稀释率为每小时发酵液流出量占发酵罐体积的０．０３和０．０６。试验日粮唯一由大豆皮组成。随着ＤＲ的提高，饲料ＤＭ，ＯＭ，ＣＰ，ＮＤＦ和ＡＤＦ消化率均没有显著变化（Ｐ＞０．０５）。提高瘤胃ＤＲ，显著提高了微生物发酵的ｐＨ（Ｐ＜０．０１），降低了发酵液中ＮＨ３的浓度（Ｐ＜０．０２），但对挥发性脂肪酸日产生量和乙、丙、丁酸比例没有显著影响（Ｐ＞０．０５）。发酵液中瘤胃细菌浓度不随ＤＲ变化而变化（Ｐ＞０．０５），但每日细菌总量随ＤＲ提高而提高（Ｐ＜０．０１）。发酵液原虫浓度（Ｐ＜０．００１）和原虫每日总产量（Ｐ＜０．０５）均随ＤＲ提高而下降。当ＤＲ从０．０３提高到０．０６时，微生物Ｎ日产生量和微生物生长效率分别提高４１．６％（Ｐ＜０．００１）和５１．９％（Ｐ＜０．００１）。

关键词：连续培养瘤胃发酵稀释率微生物生长效率

Study of Vitamin D Status in Pneumonia among Children between 6 months to 3 Years of Age

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Open Journal of Pediatrics 2021年第2期11卷 254-267页

作者： Heba A. Ismail Esaad m. menazie Shimaa m. K. Ibrahim Nashwa m. Abd Elbaky om-Almasreyyeen Hospital Egyptian Ministry of Health Giza Egypt Pediatrics Department Faculty of Medicine for Girls Al-Azhar University Cairo Egypt Clinical Pathology Department Faculty of Medicine for Girls Al-Azhar University Cairo Egypt

Background: In the developing world, pneumonia is not only more common than it is in Europe or North America;it is also more severe and considered the leading cause of under-five mortality. Effective management of pne... 详细信息

rong>Background:rong> In the developing world, pneumonia is not only more common than it is in Europe or North America;it is also more severe and considered the leading cause of under-five mortality. Effective management of pneumonia in children under 3-year-old-age is still challenging due to various causes. Some authors believed in non-calcemic role of vitamin D as a potential factor in the pathogenesis, prevention, or therapy of pneumonia in this specific age. Purpose: Investigate the Vitamin D status in pneumonia among children between 6 months to 3 years of age. Subjects and Methods: This study was conducted in a Pediatric point of care at Al-Zahraa University Hospital on 90 children aged 6 months to 3 years old;divided into two groups: group I (study group) including 47 patients presented with pneumonia and group II (control group) including 43 apparently healthy children of matched age and sex with no evidence of pneumonia. Serum vitamin D was estimated with specific inclusion and exclusion criteria. Results:

关键词： Pediatrics LrTIs 1 25(OH)2 D respiratory

Fishery resources in Arid Zone mangroves in Gulf of Kachchh, Gujarat, Northwest Coast of India

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Journal of Ocean University of China 2009年第3期8卷 233-240页

作者： A. Saravanakumar m. rajkumar J. Sesh Serebiah G. A. Thivakaran Centre of Advanced Study in marine Biology Annamalai University marine Studies and Coastal resource management Madras Christian College Gujarat Institute of Desert Ecology

The finfish and shellfish resources were assessed quantitatively and qualitatively in regard to their abundance in creek waters at three sites within a period of two years, fi＇om January 1999 to December 2000, in the western mangrove areas of Kachchh. The catch rate varied from 0.69 to 6.99kg·h^-1. It was low during monsoon （July to October）, which could be due to the freshwater-flow-induced salinity reduction in all the sites. Among 38 species recorded, 5 were shellfish and 33 were finfish. The spawning period of fishes was found to be during summer and early monsoon period （may to August）. Surface water temperatures varied from 17℃ to 37 ℃. Salinity values varied from 34 to 44 and the pH ranged between 7 and 8.9. Variation in dissolved oxygen content was from 3.42 to 5.85 mL L^-1. The high fishery densities in these semi arid mangrove creek areas were recorded during monsoon and early winter season.

关键词： mangroves Gulf of Kachchh Gujarat finfish and shellfish species diversity richness evenness