检索结果-南通市图书馆

Emerging role of A-kinase anchoring protein 5 signaling in reward circuit function

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 2913-2914页

作者： William J.Flerlage mark L.Dell’Acqua Brian m.Cox Fereshteh S.Nugent Uniformed Services University of the Health Sciences Department of Pharmacology and Molecular TherapeuticsBethesdaMDUSA Department of Pharmacology University of Colorado School of MedicineAnschutz Medical CampusAuroraCOUSA

There is a strong evidence supporting the hypothesis of synaptic dysfunction as a major contributor to neural circuit and network disruption underlying emotional and mood dysregulation in psychiatric disorders(Simmons et al.,2024).Diverse sets of distinct molecular signaling pathways converge on the synapse to regulate synaptogenesis,synaptic function,and synaptic plasticity in brain regions and circuits through complex interactions organized by numerous multivalent protein scaffolds,including the family of proteins known as A-kinase anchoring proteins(AKAPs).

关键词： function supporting

维普期刊数据库

Evaluation of the chemical constituents,antioxidant and enzyme inhibitory activities of six Yemeni green coffee beans varieties

在线全文

学校读者我要写书评

暂无评论

Food Bioscience 2022年第2期46卷 1006-1013页

作者： Ammar m.ham.ed Ahmed Ali Sakina Yagi Ahmed A.Qahtan Abdurrahman A.Alatar Simone Angeloni Filippo maggi Giovanni Caprioli eslam.m.Abdel-Salam Kouadio Ibrahime Sinan Gokhan Zengin Department of Biology Faculty of EducationHajji UniversityHajjahYemen Botany Department Faculty of ScienceUniversity of KhartoumSudan Department of Botany&microbiology College of ScienceKing Saud UniversityP.O.Box 2455Riyadh11451Saudi Arabia Chemistry Interdisciplinary Project(ChIP) School of PharmacyUniversity of CamerinoVia Madonna delle Carceri 9/BI62032CamerinoMCItaly Physiology and Biochemistry Laboratory Department of BiologyScience FacultySelcuk UniversityCampus42103KonyaTurkey

Coffee arabica *** an economical crop cultivated in many countries including *** present study evaluated the phytochemical contents of the methanolic extracts,prepared by maceration,of six Yemeni green coffee beans varieties namely Esmaeli,hamadi,Harazi,mattari,Odaini and ***(phosphomolybdenum,antiradical,reducing power and ferrous chelating),and enzyme inhibition activity of the extracts against acetylcholinesterase butyrylcholinesterase,tyrosinase,α-glucosidase,andα-amylase were also *** of total phenols revealed that all green beans varieties were richer in their total polyphenolic(63.77-110.98 mg gallic acid equivalent per g of extract)content than their flavonoids one(2.86-5.57 mg rutin equivalent per g of extract).HPLC-mS/mS analysis of 30 selected bioactive compounds showed that all varieties had the same types of phytoconstituents with differences in their relative ***(1613.89-2466.38μg/g)followed by 5-caffeoylquinic acid(1017.63-1313.39μg/g)were the dominant compounds in all varieties with caffeine more abundant in Esmaeli variety while 5-caffeoylquinic acid in Odaini *** varieties displayed a pronounced antioxidant property in all the in vitro assays with Odaini variety significantly(ped the highest anti-DPPH radicals(253.96 mg Trolox equivalent(TE)/g),metal chelating(19.73 mg Disodium edetate equivalents/g),Cu^(2+)(441.11 mg TE/g)and Fe3+(221.04 mg TE/g)reducing ***,the majority of green coffee beans varieties showed comparable enzyme inhibition property with highest activity recorded against tyrosinase(39.35-46.96 mg kojic acid equivalents/g)and acetylcholinesterase(1.80-2.17 mg galanthamine equivalents/g)*** conclusion,all Yemeni green coffee beans varieties have proven to be rich source of biochemicals with beneficial impact on human health and could be of significant applications in food,pharmaceutical and cosmetics industry.

关键词： Yemeni coffee Phytoconstituents Green coffee HPLC-mS/mS Antioxidants Enzyme inhibitory properties

multi-redox phenazine/non-oxidized graphene/cellulose nanohybrids as ultrathick cathodes for high-energy organic batteries

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2021年第5期14卷 1382-1389页

作者： Youngjin ham Vitalii Ri Jin Kim Yeoheung Yoon Jinho Lee Kisuk Kang Ki-Seok An Chunjoong Kim Seokwoo Jeon Department of materials Science and Engineering Advanced Battery CenterKorea Advanced Institute of Science and Technology(KAIST)Daejeon34141Republic of Korea Department of materials Science and Engineering Chungnam National UniversityDaejeon34134Republic of Korea Thin Film materials Research Center Korea Research Institute of Chemical Technology(KRICT)Daejeon34114Republic of Korea Department of materials Science and Engineering Seoul National UniversitySeoul08826Republic of Korea

Various redox-active organic molecules can serve as ideal electrode materials to realize sustainable energy storage systems. Yet, to be more appropriate for practical use, considerable architectural engineering of an ultrathick, high-loaded organic electrode with reliable electrochemical performance is of crucial importance. Here, by utilizing the synergetic effect of the non-covalent functionalization of highly conductive non-oxidized graphene flakes (NOGFs) and introduction of mechanically robust cellulose nanofiber (CNF)-intermingled structure, a very thick (≈ 1 mm), freestanding organic nanohybrid electrode which ensures the superiority in cycle stability and areal capacity is reported. The well-developed ion/electron pathways throughout the entire thickness and the enhanced kinetics of electrochemical reactions in the ultrathick 5,10-dihydro-5,10-dimethylphenazine/NOGF/CNF (DmPZ-NC) cathodes lead to the high areal energy of 9.4 mWh·cm−2 (= 864 Wh·kg−1 at 158 W·kg−1). This novel ultrathick electrode architecture provides a general platform for the development of the high-performance organic battery electrodes.

关键词： energy storage organic electrodes batteries graphene cellulose nanofibers

Crop Discrimination Using Field Hyper Spectral Remotely Sensed Data

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Advances in Remote Sensing 2013年第2期2卷 63-70页

作者： Sayed m. Arafat mohamed A. Aboelghar eslam.F. Ahmed Agriculture Applications Department National Authority for Remote Sensing and Space Sciences (NARSS)Cairo Egypt

Crop discrimination through satellite imagery is still problematic. Accuracy of crop classification for high spatial resolution satellite imagery in the intensively cultivated lands of the Egyptian Nile delta is still low. Therefore, the main objective of this research is to determine the optimal hyperspectral wavebands in the spectral range of (400 - 2500 nm) to discriminate between two winter crops (Wheat and Clover) and two summer crops (maize and Rice). This is considered as a first step to improve crop classification through satellite imagery in the intensively cultivated areas in Egypt. Hyperspectral ground measurements of ASD field Spec3 spectroradiometer was used to monitor the spectral reflectance profile during the period of the maximum growth stage of the four crops. 1-nm-wide was aggregated to 10-nm-wide bandwidths. After accounting for atmospheric windows and/or areas of significant noise, a total of 2150 narrow bands in 400 - 2500 nm were used in the analysis. Spectral reflectance was divided into six spectral zones: blue, green, red, near-infrared, shortwave infrared-I and shortwave infrared-II. One Way ANOVA and Tukey’s HSD post hoc analysis was performed to choose the optimal spectral zone that could be used to differentiate the different crops. Then, linear regression discrimination (LDA) was used to identify the specific optimal wavebands in the spectral zones in which each crop could be spectrally identified. The results of Tukey’s HSD showed that blue, NIR, SWIR-1 and SWIR-2 spectral zones are more sufficient in the discrimination between wheat and clover than green and red spectral zones. At the same time, all spectral zones were quite sufficient to discriminate between rice and maize. The results of (LDA) showed that the wavelength zone (727:1299 nm) was the optimal to identify clover crop while three zones (350:712, 1451:1562, 1951:2349 nm) could be used to identify wheat crop. The spectral zone (730:1299 nm) was the optimal to identify maize

关键词： Hyper Spectral Data Crop Discrimination

mechanism of frost heave by film water migration under temperature gradient

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Science Bulletin 1997年第15期42卷 1290-1294页

作者： Xu, XZ Wang, JC Zhang, LX Deng, YS Chuvilin, Em Yershov, ed Ishizaki, T Fukuda, m State Key Laboratory of Frozen Soil Engineering Lanzhou Institute of Glaciology and Geocryology Chinese Academy of Sciences Lanzhou China Geological Faculty of moscow University Russia Institute of Low Temperature Science Hokkaido University Japan

IT is well known that there exists unfrozen film water in frozen soils due to the action of sur-face energy among soil particles and frost heave occurs by water migration under the tempera-ture gradient. The problem is how to determine the amount of frost heave quantitatively. The amount of frost heave induced by ice segregation can be calculated by the following e-quations:

关键词： temperature gradient film water frost heave.

维普期刊数据库

Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2454-2463页

作者： Victoria Jiménez Carretero IrisÁlvarez-merz Jorge Hernández-Campano Sergei A.Kirov Jesús m.Hernández-Guijo Department of Pharmacology and Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ramón y Cajal Institute for Health Research(IRYCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain Institute of Neurobiology Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neuroscience and Regenerative medicine&Department of Neurosurgery Medical College of Georgia at Augusta UniversityAugustaGAUSA

The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is ***,the role of non-excitatory amino acids in brain damage following a stroke or brain trauma remains largely *** release of amino acids by necrotic cells in the ischemic core may contribute to the expansion of the *** findings indicated that the reversible loss of field excitato ry postsynaptic potentials caused by transient hypoxia became irreversible when exposed to a mixture of just four non-excitatory amino acids(L-alanine,glycine,L-glutamine,and L-serine)at their plasma *** amino acids induce swelling in the somas of neurons and astrocytes during hypoxia,along with permanent dendritic damage mediated by N-methyl-D-aspartate *** N-methyl-D-aspartate receptors prevented neuronal damage in the presence of these amino acids during *** is likely that astroglial swelling caused by the accumulation of these amino acids via the alanine-serine-cysteine transporter 2 exchanger and system N transporters activates volume-regulated anion channels,leading to the release of excitotoxins and subsequent neuronal damage through N-methyl-D-aspartate receptor ***,previously unrecognized mechanisms involving non-excitatory amino acids may contribute to the progression and expansion of brain injury in neurological emergencies such as stroke and traumatic brain *** these pathways co uld highlight new therapeutic targets to mitigate brain injury.

关键词： cell swelling N-methyl-D-aspartate receptor non-excitatory amino acids stroke synaptic transmission

维普期刊数据库

Your Life Is a mirror

在线全文

学校读者我要写书评

暂无评论

英语通（高三版） 2004年第6期 46-48,62页

作者： m．ed Bymyriammaytorena

一个人要善于调节自己，要对自己充满自信。无论何时何地，都要心态平和，内视自省，修身养性，勇于承担责任。还要记住：Walk in the light but do not fear the darkness.

关键词：高中英语阅读训练参考答案阅读理解题

microalgae-based wastewater treatment:mechanisms,challenges,recent advances,and future prospects

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Environmental Science and Ecotechnology 2023年第1期13卷 5-22页

作者： Abdallah Abdelfattah Sameh Samir Ali Hassan Ramadan eslam.Ibrahim El-Aswar Reham Eltawab Shih-Hsin Ho Tamer Elsamahy Shengnan Li mostafa m.El-Sheekh michael Schagerl michael Kornaros Jianzhong Sun School of Environment and Safety Engineering Jiangsu UniversityZhenjiang212013PR China Department of Public Works Engineering Faculty of EngineeringTanta UniversityTanta31511Egypt Biofuels Institute School of the Environment and Safety EngineeringJiangsu UniversityZhenjiang212013PR China Botany Department Faculty of ScienceTanta UniversityTanta31527Egypt Central Laboratories for Environmental Quality monitoring(CLEQm) National Water Research Center(NWRC)El-Kanater13621QalyubiyahEgypt State Key Laboratory of Urban Water Resource and Environment School of EnvironmentHarbin Institute of TechnologyHarbin150090PR China Department of Functional and Evolutionary Ecology University of ViennaDjerassiplatz 1A-1030 ViennaAustria Laboratory of Biochemical Engineering&Environmental Technology(LBEET) Department of Chemical EngineeringUniversity of Patras1 Karatheodori Str.University Campus26504PatrasGreece

The rapid expansion of both the global economy and the human population has led to a shortage of water resources suitable for direct human *** a result,water remediation will inexorably become the primary focus on a global *** can be grown in various types of wastewaters(WW).They have a high potential to remove contaminants from the effluents of industries and urban *** review focuses on recent advances on WW remediation through microalgae *** has already been paid to microalgae-based wastewater treatment(WWT)due to its low energy requirements,the strong ability of microalgae to thrive under diverse environmental conditions,and the potential to transform WW nutrients into high-value *** turned out that microalgae-based WWT is an economical and sustainable ***,different types of toxins are removed by microalgae through biosorption,bioaccumulation,and biodegradation *** are toxins from agricultural runoffs and textile and pharmaceutical industrial *** have the potential to mitigate carbon dioxide and make use of the micronutrients that are present in the *** review paper highlights the application of microalgae in WW remediation and the remediation of diverse types of pollutants commonly present in WW through different mechanisms,simultaneous resource recovery,and efficient microalgae-based co-culturing systems along with bottlenecks and prospects.

关键词： Bioremediation Wastewater treatment Environmental applications microalgae Co-culturing

Fundamental principles and development of proximity-field nanopatterning toward advanced 3D nanofabrication

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2021年第9期14卷 2965-2980页

作者： Sang-Hyeon Nam Gayea Hyun Donghwi Cho Seonggon Han Gwangmin Bae Haomin Chen Kisun Kim Youngjin ham Junyong Park Seokwoo Jeon Department of materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Department of mechanical and Aerospace Engineering The Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina School of materials Science and Engineering Kumoh National Institute of TechnologyGumiGyeongbuk 39177Republic of Korea Department of Energy Engineering Convergence Kumoh National Institute of TechnologyGumiGyeongbuk 39177Republic of Korea KAIST Institute for NanoCentury(KINC) KAISTDaejeon 34141Republic of Korea

Three-dimensional(3D)nanoarchitectures have offered unprecedented material performances in diverse applications like energy storages,catalysts,electronic,mechanical,and photonic *** outstanding performances are attributed to unusual material properties at the nanoscale,enormous surface areas,a geometrical uniqueness,and comparable feature sizes with optical *** the practical use of the unusual nanoscale properties,there have been developments for macroscale fabrications of the 3D nanoarchitectures with process areas over centimeter *** the many fabrication methods for 3D structures at the nanoscale,proximity-field nanopatterning(PnP)is one of the promising techniques that generates 3D optical holographic images and transforms them into material structures through a lithographic *** conformal and transparent phase masks as a key factor,the PnP process has advantages in terms of stability,uniformity,and reproducibility for 3D nanostructures with periods from 300 nm to several *** merits of realizing precise 3D features with sub-100 nm and rapid processes are attributed to the interference of coherent light diffracted by phase *** this review,to report the overall progress of PnP from 2003,we present a comprehensive understanding of PnP,including its brief history,the fundamental principles,symmetry control of 3D nanoarchitectures,material issues for the phase masks,and the process area expansion to the wafer-scale for the target ***,technical challenges and prospects are discussed for further development and practical applications of the PnP technique.

关键词： proximity-field nanopatterning three-dimensional(3D)nanostructures phase mask interference lithography