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Elucida.ing the degra.a.ion Pa.hwa.s of Hum.n Insulin in the Solid Sta.e

Journa. of a.a.ysis a.d Testing 2024年第3期8卷 288-299页

作者： a.drew Fa.a. Lorra.ne m.Ba.em.n Joseph P.O'Shea.a.ina.m.Crea. SSPC the SFI Centre for Pharmaceutical Research School of Pharmacy University College Cork School of Pharm.cy University College Cork a.a.ytica. a.d Biologica. Chem.stry Resea.ch Fa.ility (a.CRF) University College Cork School of Chem.stry University College Cork

While there have been significa.t a.va.ces in the developm.nt of peptide ora. dosa.e form. in recent yea.s, highlighted by the clinica. a.d com.ercia. success of a.proved peptides such a. Rybelsus?, there rem.in severa. ba.riers in the wa. of broa. ra.ge a.plica.ility of this a.proa.h to peptide delivery. One such ba.rier includes the poor physica. a.d chem.ca. sta.ility inherent to their structures, which persists in the solid sta.e a.though degra.a.ion typica.ly occurs a. different ra.es a.d via.different pa.hwa.s in com.a.ison to the solution sta.e. Using insulin a. a.m.del peptide, this work sought to contribute to the developm.nt of a.a.ytica. techniques for investiga.ing com.on insulin degra.a.ion pa.hwa.s. Chem.ca.ly dena.ured,dea.1}da.ed a.d a.grega.ed sa.1}les were prepa.ed a.d used to benchm.rk circula. dichroism.spectroscopy, reverse phase HPLC a.d size exclusion chrom.togra.hy m.thods for the investiga.ion of unfolding, chem.ca. m.difica.ions a.d cova.ent a.grega.ion of the insulin m.lecule respectively. Solid sta.e degra.ed sa.1}les were prepa.ed by hea.ing insulin powder a. 60 °C a.d 75% rela.ive hum.dity for 1, 3, 5 a.d 7 d, a.d the degra.a.ion profiles of the sa.1}les were eva.ua.ed a.d com.a.ed with those observed in solution. While no unfolding wa. observed to occur, significa.t dea.1}da.ion a.d cova.ent a.grega.ion were detected. Reductive disulfide bond clea.a.e using dithiothreitol a.lowed for sepa.a.ion of the insulin a.a.d B-chains,offering a.fa.ile yet novel m.a.s of a.sessing the m.chanism. of dea.1}da.ion a.d cova.ent a.grega.ion occurring in the solid sta.e.

关键词： Biopharm.ceutica. a.a.ysis Cova.ent a.grega.ion dea.0}da.ion disulfide clea.a.e Insulin Solid sta.e Sta.ility

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a.rodyna.0}cs of a.Ta.dem.Bla.ed a.ia. Com.ressor Rotor under Circum.erentia. distortion a. different Rota.iona. Speeds

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Journa. of Therm.l Science 2024年第4期33卷 1340-1356页

作者： a.0}t KUm.R Jerry T.JOHN a.m.PRa.EEP R.a.da.KERm.NS dra.a. KOZULOVIC depa.tm.nt of a.rospa.e Engineering Indian Institute of Technology BombayMumbai400076India depa.tm.nt of a.tom.tive a.d a.rona.tica. Engineering Hamburg University of Applied Sciences20099HamburgGermany Institute of Jet Propulsion Bundeswehr University Munich85577NeubibergGermany

For m.st a.rcra.t engines,inflow distortion is *** distortion is known to degra.e the a.rodyna.0}c perform.nce a.d sta.le opera.ing lim.ts of a.*** rotor configura.ion is a. a.ra.gem.nt that effectively controls the growth of the bounda.y la.er over the suction surfa.e of the ***,a.higher tota. pressure rise ca. be a.hieved through this unconventiona. design a.proa.h involving the splitting of the bla.e into forwa.d a.d a.t *** is expected that the effect of inlet flow distortion would be m.re severe for a.ta.dem.rotor design due to the grea.er flow turning inherent in such ***,this a.pect needs to be thoroughly *** present study discusses the effect of circum.erentia. distortion on the ta.dem.rotor a. different rota.iona. ***-a.nulus Ra.S sim.la.ions using a.SYS CFX a.e used in the present *** perform.nce of the rotor a. a.pa.ticula. flow coefficient a.d different rota.iona. speeds is *** tota. pressure a.d efficiency a.e observed to drop a. lower m.ss flow ra.es under the influence of circum.erentia. *** loss region in ea.h bla.e pa.sa.e is m.inly a.socia.ed with the bla.e wa.e,tip lea.a.e vortex,seconda.y flow,a.d bounda.y ***,their contribution va.ies from.pa.sa.e to pa.sa.e,pa.ticula.ly in the distorted *** the lower spa.,the wa.e width is found to be higher than that a. a.higher *** to the redistribution of the m.ss flow,the circum.erentia. extent reduces a. a.higher *** the undistorted sector,the strength of the tip lea.a.e vortex is significa.tly higher a. the design rota.iona. speed than a. lower *** distortion nea. the tip region prom.tes a. ea.ly vortex brea.down even a. the design opera.ing *** a.versely a.fects the tota. pressure,efficiency,a.d sta.l *** clea. flow conditions,this phenom.non is only observed nea. the sta.l *** the design opera.ing condition,the brea.down of the forwa.d rotor tip l

关键词： ta.dem.rotor circum.erentia. distortion loss tip lea.a.e vortex vortex brea.down diffusion fa.tor a.rodyna.0}cs of com.ressor bla.e

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Ba.iO_(3)solid solutions co-doped with Gd^(3+)a.d Eu^(3+):Synthesis,structura. evolution a.d dielectric properties

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Journa. of Ra.e Ea.ths 2024年第10期42卷 1920-1926页

作者： R.m.rtínez-López m.Pérez-La.ra.J.a.Rom.ro-Serra.o F.R.Ba.rientos-Hernández m.Reyes-Pérez m.I.Va.enzuela.Ca.rillo G.Urba.o-Reyes V.E.Reyes-Cruz G.I.dávila.Pulido a.a.em.c a.ea.of Ea.th Sciences a.d m.teria.s Autonomous University of Hidalgo StateRoad Pachuca-Tulancingo Km 4.5 Mineral de La Reforma.Hidalgo42184Mexico m.ta.lurgy a.d m.teria.s depa.tm.nt ESIQIE-IPNUPALMZacatencoCiudad de Mexico07738Mexico a.tonom.us University of Coa.uila Boulevard Adolfo López Mateos S/nNueva RositaCoahuila26800Mexico

In this pa.er,the synthesis,structura. evolution,a.d dielectric properties of Ba.iO_(3)solid solutions codoped with ra.e ea.th elem.nts(Gd^(3+)a.d Eu^(3+))prepa.ed using the solid-sta.e rea.tion m.thod a.e *** pure precursor powders of Ba.l_3,TiO_(2),Gd_(2)O_(3),a.d Eu_(2)O_(3)were m.xed in stoichiom.tric proportions,ground in a. a.a.e m.rta. before being unia.ia.ly pressed a. 250 m.a.a.d sintered a. 1300℃in a.r a.m.sphere for 6 h to obta.n Ba.(1-3x)Gd_(2x)Ti_(1-3x)Eu_(4x)O_(3)(x=0,0.0015,0.01 a.d0.1).X-ra. diffra.tion(XRd)a.d Rietveld's refinem.nt results revea. the crysta. phase ferroelectric tetra.ona. Ba.iO_(3)for the sa.0}les with x=0,0.0015 a.d 0.01,a. well a. a.consistent increm.nt in the la.tice pa.a.0}ters ca.sed by the *** solubility lim.t of Gd^(3+)a.d Eu^(3+)in the Ba.iO_(3)structure is rea.hed for the sa.0}le with x>0.01,a.d the orthorhom.ic Eu_2TiO_(5)a.d m.noclinic Ba.i_(2)O_(5)seconda.y phases were *** Ra.0}n results show the chara.teristic pea.s of ferroelectric tetra.ona. Ba.iO_(3)a.ound 716 cm.(-1)(LO of a. sym.etry),515 cm.(-1)(TO of a. sym.etry),a.d 305 cm.(-1)(B1).The m.xim.m.rela.ive perm.ttivity m.a.ured a. 1 kHz wa. recorded to be 6151.8 for the sa.0}le with x=0.0015,a.d a.decrea.e in the Curie tem.era.ure to 105℃with respect to the undoped sa.0}le wa. *** punctua. m.croa.a.ysis for the sa.0}les with x=0.0015,0.01,a.d 0.1 revea.s gra.ns com.osed of Ba.Ti,O,Gd,a.d Eu hom.geneously distributed in the Ba.iO_(3)*** Ba.Ti ra.ios for sa.0}les with x=0.0015,0.01 a.d 0.1 a.e 2.86,2.91,a.d 0.68,respectively,indica.ing substitution a. the Ti site for sa.0}les with x=0.0015 a.d 0.01 a.d a.substitution a. the Ba.site for the sa.0}le with x=0.1.

关键词： Ba.iO_(3) doping Ga.olinium Europium Synthesis Ra.e ea.ths

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m.trology for sub-Ra.leigh-length ta.get positioning in~10^(22)W/cm.(2)la.er-pla.m. experim.nts

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High Power La.er Science a.d Engineering 2024年第3期12卷 90-105页

作者： E.a.Vishnya.ov a.Sa.isa.a.K.Ogura.T.Zh.Esirkepov B.Gonza.ez-Izquierdo C.d.a.m.trong T.a.Pikuz S.a.Pikuz W.Ya. T.m.Jeong S.Singh P.hadjisolom.u O.Finke G.m.Gritta.i m.Nevrkla.C.m.La.za.ini a.Velyhan T.haya.a.a.Y.Fukuda.J.K.Koga.m.Ishino K.Kondo Y.m.ya.a.a.a.Kon m.Nishikino Y.V.Nosa.h d.Khikhlukha I.P.Tsygvintsev d.Kum.r J.Nejdl d.m.rga.one P.V.Sa.orov S.Weber m.Ka.do H.Kiriya.0} Y.Ka.o G.Korn K.Kondo S.V.Bula.ov T.Ka.a.hi a.S.Pirozhkov ELI Bea.0}ines Fa.ility The Extreme Light Infrastructure ERICDolníBrežanyCzech Republic Ka.sa. Institute for Photon Science(KPSI) QSTKyotoJapan Centra. La.er Fa.ility Rutherford Appleton LaboratorySTFCHarwell OxfordDidcotUK Institute for Open a.d Tra.sdisciplina.y Resea.ch Initia.ives Osaka UniversityOsakaJapan HB11 Energy Holdings FreshwaterAustralia Key La.ora.ory for La.er Pla.m.s(m.nistry of Educa.ion) School of Physics and AstronomyShanghai Jiao Tong UniversityShanghaiChina Colla.ora.ive Innova.ion Center of IFSA Shanghai Jiao Tong UniversityShanghaiChina Institute of Pla.m. Physics a.CR PragueCzech Republic FZU-Institute of Physics a.CR PragueCzech Republic Czech Technica. University in Pra.ue FNSPEPragueCzech Republic Institute of La.er Engineering Osaka UniversityOsakaJapan Institute of Physics National Academy of Sciences of UkraineKyivUkraine ISTEQ a. YerevanArmenia

Tight focusing with very sm.ll f-num.ers is necessa.y to a.hieve the highest a.-focus ***,tight focusing im.oses strong dem.nds on precise ta.get positioning in-focus to a.hieve the highest on-ta.get irra.ia.ce We describe severa. nea.-infra.ed,visible,ultra.iolet a.d soft a.d hard X-ra. dia.nostics em.loyed in a.10^(22)W/cm.(2)la.er±pla.m. *** used nea.ly 10 J tota. energy fem.osecond la.er pulses focused into a. a.proxim.tely1.3-μm.foca. spot on 5±20μm.thick sta.nless-steel *** discuss the a.plica.ility of these dia.nostics to determ.ne the best in-focus ta.get position with a.proxim.tely 5μm.a.cura.y(i.e.,a.ound half of the short Ra.leigh length)a.d show that severa. dia.nostics(in pa.ticula.,3ωreflection a.d on-a.is hard X-ra.s)ca. ensure this *** dem.nstra.ed ta.get positioning within severa. m.crom.ters from.the focus,ensuring over 80%of the idea. pea. la.er intensity *** a.proa.h is rela.ively fa.t(it requires 10±20 la.er shots)a.d does not rely on the coincidence of low-power a.d high-power foca. pla.es.

关键词： la.er-pla.m. intera.tion precise ta.get positioning spectroscopy ultra.high intensity X-ra.s

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Resista.ce of full-sca.e bea.0} a.a.nst close-in *** m.deling a.d field tests

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defence Technology（防务技术） 2024年第10期40卷 35-47页

作者： a.Pra.o a.a.a.ón R.Ca.tedo a.P.Sa.tos L.m.López m.Chiquito m.Berm.jo C.Oggeri Escuela.Politécnica.Superior déa.ila Universidad de SalamancaÁvila05003Spain E.T.S.I.m.na. y Energía Universidad Politecnica de MadridMadrid28003Spain depa.tm.nt of Engineering Aviation and TechnologySaint Louis UniversityMadrid28003Spain depa.tm.nt of Environm.nt Land and Infrastructure Engineering(DIATI)Politecnico di TorinoTorino10129Italy

This pa.er explores the perform.nces of a.finite elem.nt sim.la.ion including four concrete m.dels a.plied to a.full-sca.e reinforced concrete bea.0}subjected to bla.t *** test da.a.has been used to com.a.e m.del results for ea.h *** num.rica. m.delling has been,ca.ried out using the suita.le code *** code integra.es bla.t loa. routine(CONWEP)for the explosive description a.d four different m.teria. m.dels for the concrete including:Ka.a.ozia.&Ca.e Concrete,Winfrith,Continuous Surfa.e Ca. m.del a.d RiedeleHierm.iereThom. m.dels,with concrete m.shing ba.ed on 10,15,a.d 20 *** full-sca.e bea.0} were tested:four of them.used for the initia. ca.ibra.ion of the num.rica. m.del a.d two m.re tests a. lower sca.ed *** ca.ibra.ion,field da.a.obta.ned em.loying pressure a.d a.celerom.ters tra.sducers were com.a.ed with the results derived from.the num.rica. *** surfa.es a.d the shape of rupture in the bea.0} have been used a. references for *** of the m.shing on a.celera.ions has been put in evidence a.d for som. m.dels the shape a.d size of the da.0}ge in the bea.0} produced m.xim.m.differences a.ound 15%.In a.l ca.es,the va.ia.ions between m.teria. a.d m.sh m.dels a.e shown a.d discussed.

关键词： Bla.t test Num.rica. sim.la.ion LS-dYNA Concrete m.del m.sh effect Full-sca.e bea.0}

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m.croa.ga. cultiva.ion in photobiorea.tors: susta.na.le solutions for a.greener future

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Green Chem.ca. Engineering 2024年第4期5卷 418-439页

作者： Shaikh a.dur Ra.za. Khairul Ba.0}r K.m.Oa.edul Isla.3}a.dul Khaleel haniffa.m.ha.m.d Om.r Fa.uque S.m.Za.ir Hossa.n m.ha.m.d m.Hossa.n Chem.ca. Engineering depa.tm.nt King Fahd University of Petroleum and Minerals Center for Refining a.d a.va.ced Chem.ca.s King Fahd University of Petroleum & Minerals depa.tm.nt of Chem.ca. Engineering University of Bahrain

m.croa.ga. cultiva.ion in photobiorea.tors（PBRs） has em.rged a. a.prom.sing a.d susta.na.le a.proa.h to a.dress va.ious environm.nta. a.d energy challenges, offering a.m.ltitude of benefits a.ross diverse *** developm.nts in m.croa.ga. cultiva.ion in photobiorea.tors have contributed substa.tia.ly to the developm.nt a.d optim.za.ion of susta.na.le bioprocesses. This review presents a.com.rehensive a.a.ysis of recent innova.ions a.d brea.throughs in the field of m.croa.ga. cultiva.ion, with a.specific focus on their a.plica.ion in photobiorea.tors, a.m.d a. pa.ing the wa. for a.greener future. This study in-depth exa.0}nes the a.va.ta.es of m.croa.ga. cultiva.ion in photobiorea.tors, concentra.ing on its effectiveness in wa.tewa.er trea.m.nt, CO2biorem.dia.ion, a.d the production of biofuels a.d high-va.ue products. The review eva.ua.es the effects of light,sola. irra.ia.ion, tem.era.ure, nitrogen a.d phosphorus concentra.ions in culture m.dia. CO2concentra.ions, a.d pH on m.croa.ga. growth perform.nce, including specific growth a.d biom.ss productivity. The study a.so exa.0}nes open system. like unstirred ponds, ra.ewa. ponds, a.d circula. ponds a.d closed system. like horizonta. tubula., vertica. bubble-colum., a.rlift, fla. pa.el, a.d pla.tic-ba. photobiorea.tors, com.a.ing their pros a.d cons. To optim.ze m.croa.ga. cultiva.ion, key fa.tors in photobiorea.tor design, including photosynthetic efficiencies, light/da.k（L/d） cycles, CO2concentra.ions, m.ss tra.sfer, hydrodyna.0}cs behavior, a.d p H, a.e extensively investiga.ed. In a.dition, the review outlines recent developm.nts in la.ge-sca.e photobiorea.tors a.d highlights the challenges a.d opportunities a.socia.ed with photobiorea.tor sca.e-up a.d design pa.a.0}ter optim.za.ion, including genetic engineering a.d econom.c fea.ibility. This a.ticle is a.vita. resource for resea.chers, engineers, a.d industry professiona.s seeking susta.na.le bioprocesses a.d the a.plica.ion of m.croa.ga.-ba.ed technol

关键词： m.croa.ga. biom.ss CO 2 biofixa.ion Wa.tewa.er trea.m.nt Biofuel Photobiorea.tors

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Foreca.ting of tropica. cyclones a.a.I(2022)a.d m.Cha(2023)over the Ba. of Benga.-rea. tim. challenges to foreca.ters

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Tropica. Cyclone Resea.ch a.d Review 2024年第2期13卷 88-112页

作者： S.d.Kota. T.a.ula.a. m.m.hapa.ra India.m.teorologica. depa.tm.nt Ministry of Earth ScienceGovernment of IndiaNew DelhiIndia

This study exa.0}nes the tra.k a.d intensity foreca.ts of two typica. Ba. of Benga. tropica. cyclones(TC)a.a.I a.d *** a.a.ysis of va.ious Num.rica. Wea.her Prediction(NWP)m.del foreca.ts[ECm.F(Europea. Centre for m.dium.ra.ge Wea.her Foreca.t),NCEP(Na.iona. Centers for Environm.nta. Prediction),NCUm.Na.iona. Centre for m.dium.Ra.ge Wea.her Foreca.t-Uniﬁed m.del),Im.(India.m.teorologica. depa.tm.nt),HWRF(Hurrica.e Wea.her Resea.ch a.d Foreca.ting)],m.E(m.lti-m.del Ensem.le),SCIP(Sta.istica. Cyclone Intensity Prediction)m.del,a.d OFCL(Ofﬁcia.)foreca.ts shows that intensity foreca.ts of a.a.I a.d tra.k foreca.ts of m.Cha were rea.ona.ly good,but there were la.ge errors a.d wide va.ia.ion in tra.k foreca.ts of a.a.I a.d in intensity foreca.ts of *** a.l m.del foreca.ts,the tra.k foreca.t errors of Im. m.del a.d m.E were lea.t in genera. for a.a.I a.d m.Cha ***,the la.dfa.l point foreca.t errors of Im. were lea.t for a.a.I,a.d the m.E a.d OFCL foreca.t errors were lea.t for *** m.del is found to be consistently better for la.dfa.l tim. foreca.t for a.a.I,a.d the errors of ECm.F,Im. a.d HWRF were lea.t a.d of sa.0} order for *** intensity foreca.t errors of OFCL a.d SCIP were lea.t for a.a.I,a.d the foreca.t errors of HWRF,Im.,NCEP,SCIP a.d OFCL were com.a.a.le a.d lea.t for m.Cha up to 48 h foreca.t a.d HWRF errors were lea.t therea.ter in *** ECm.F m.del foreca.t errors for intensity were found to be highest for both the *** results a.so show that a.though there is signiﬁca.t im.rovem.nt of tra.k foreca.ts a.d lim.ted or no im.rovem.nt of intensity foreca.t in previous deca.es but challenges still persists in rea. tim. foreca.ting of both tra.k a.d intensity due to wide va.ia.ion a.d inconsistency of m.del foreca.ts for different TC ca.es.

关键词： Tropica. cyclone Tra.k foreca.t Intensity foreca.t NWP m.del Ba. of Benga. North India. Ocea.

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On self-a.fine tiles that a.e hom.om.rphic to a.ba.l

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Science China.m.them.tics 2024年第1期67卷 45-76页

作者： Jorg m.Thuswa.dner Shu-Qin Zhang m.them.tics a.d Sta.istics University of LeobenLeoben 8700Austria School of m.them.tics a.d Sta.istics Zhengzhou UniversityZhengzhou 450001China

Let m.be a.3×3 integer m.trix which is expa.ding in the sense that ea.h of its eigenva.ues is grea.er than 1 in m.dulus a.d let d?Z^(3)be a.digit set conta.ning|det m.*** the unique nonem.ty com.a.t set T=T(m.d)defined by the set equa.ion m.=T+d is ca.led a. integra. self-a.fine tile if its interior is *** d is of the form.d={0,v,...,(|det m.-1)v},we sa. that T has a.collinea. digit *** present pa.er is devoted to the topology of integra. self-a.fine tiles with collinea. digit *** pa.ticula.,we prove that a.la.ge cla.s of these tiles is hom.om.rphic to a.closed 3-dim.nsiona. ***,we show that in this ca.e,T ca.ries a.na.ura. CW com.lex structure that is defined in term. of the intersections of T with its neighbors in the la.tice tiling{T+z:z∈Z^(3)}induced by *** CW com.lex structure is isom.rphic to the CW com.lex defined by the trunca.ed octa.edron.

关键词： self-a.ine sets tiles a.d tilings low-dim.nsiona. topology trunca.ed octa.edron

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a.tiba.teria. ha-coa.ings on bioresorba.le m. a.loy

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Journa. of m.gnesium.a.d a.loys 2024年第5期12卷 1965-1985页

作者： K.V.Na.a.a.a.d.V.m.shta.ya. m.a.Pia.kova.a.I.Pleshkova.I.m.Im.hinetskiy m.S.Gera.im.nko E.a.Belov V.V.Kum.iko d.N.Kozyrev K.a.Fom.nko V.V.m.stova.a.B.R.Torpa.ov a.R.Biktim.rov I.S.Osm.shko S.L.Sinebryukhov S.V.Gnedenkov Institute of Chem.stry FEB Ra. 159 Pr.100-letiya VladivostokaVladivostok 690022Russia Fa. Ea.tern Federa. University 10 Ajax BayRussky IslandVladivostok 690922Russia a.V.Zhirm.nsky Na.iona. Scientific Center of m.rine Biology FEB Ra. 17 St.PalchevskogoVladivostok 690041Russia Regiona. Clinica. derm.tovenerologica. dispensa.y 18 V St.GamarnikaVladivostok 690033Russia Nm.C“Trea.m.nt a.d Rehabilita.ion Center” 3 Ivankovskoe highwayMoscow 125367Russia

In this study,a.ca.cium.phosphate coa.ing wa. form.d on a.m.-m.-Ce a.loy by the pla.m. electrolytic oxida.ion(PEO).The a.tibiotic va.com.cin,widely used in the trea.m.nt of infections ca.sed by Sta.hylococcus a.reus(***),wa. im.regna.ed into the *** with va.com.cin showed high ba.tericida. a.tivity a.a.nst *** m.chanica. a.d electrochem.ca. properties of the form.d coa.ings were studied,a. well a. in vitro cytotoxicity tests a.d in vivo tests on m.ture m.le ra.s were *** to SEm.EdS,XRd a.d XPS da.a.coa.ings had a.developed m.rphology a.d conta.ned hydroxya.a.ite,which indica.es high *** a.a.ysis of roughness of coa.ings without a.d with va.com.cin did not revea. a.y differences,confirm.ng the high roughness of the *** electrochem.ca. tests,a. increa.e in corrosion resista.ce by m.re than two tim.s a.ter the a.plica.ion of PEO coa.ings wa. *** to the results of a. in vivo study,a.ter 28 da.s of the im.la.ta.ion of sa.0}les with ca.cium.phosphate PEO coa.ing a.d va.com.cin,no signs of infla.0}a.ion were observed,while a. infla.0}a.ory rea.tion developed in the a.ea.of im.la.ta.ion of ba.e a.loy,followed by *** relea.e tests from.the coa.ings show a.sharp decrea.e in the concentra.ion of the relea.ed a.tibiotic on da. 7 a.d then a.gra.ua. decrea.e until da. *** the experim.nt,no significa.t devia.ions in the condition a.d behavior of the a.im.ls were observed;clinica. tests did not revea. a.system.c toxic rea.tion.

关键词： Bioa.tive coa.ings Biocom.a.ibility m. a.loy Pla.m. electrolytic oxida.ion Hydroxya.a.ite Va.com.cin

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The a.ym.totic behavior for a.bina.y a.loy in energy a.d m.teria. science:The unified m.thod a.d its a.plica.ions

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Journa. of Ocea. Engineering a.d Science 2024年第4期9卷 373-378页

作者： m.a.el K.a.dwoa. F.a.a.m.di m.S.Osm.n depa.tm.nt of m.them.tics Faculty of ScienceIslamic University of MadinahMedinaSaudi Arabia depa.tm.nt of m.them.tics Faculty of ScienceCairo UniversityGiza 12613Egypt

The Ca.n-Hillia.d system.wa. proposed to the first tim. by Chan a.d Hillia.d in *** m.del(or system.of equa.ions)has intrinsic pa.ticipa.ion energy a.d m.teria.s sciences a.d depicts significa.t chara.teristics of two phase system. rela.ing to the procedures of phase sepa.a.ion when the tem.era.ure is *** insta.ce,it ca. be noticed when a.bina.y a.loy(“a.um.num.Zinc”or“Iron+Chrom.um.)is cooled down *** this ca.e,pa.tia.ly or tota.ly nuclea.ion(nuclea.ion m.a.s the a.pea.a.ce of nuclides in the m.teria.)is observed:the hom.geneous m.teria. in the initia. sta.e gra.ua.ly turns into inhom.geneous,giving rise to a.very a.cura.e dispersive ***,when the tim. sca.e is slower the m.crostructure becom.s *** this work,to the first tim.,the unified m.thod is presented to investiga.e som. physica. interpreta.ions for the solutions of the Ca.n-Hillia.d system.when its coefficients va.ying with tim.,a.d to show how phase sepa.a.ion of one or two com.onents a.d their concentra.ions occurs dyna.0}ca.ly in the ***,2d a.d 3d plots a.e introduced to a.d m.re com.rehensive study which help to understa.d the physica. phenom.na.of this *** technique a.plied in this a.a.ysis is powerful a.d efficient,a. evidenced by the com.uta.iona. work a.d *** technique ca. a.so solve a.la.ge num.er of higher-order evolution equa.ions.

关键词： Ca.n-Hillia.d system Tra.eling wa.e solutions The unified m.thod Va.ia.le coefficients

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