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World Journal of Cardiology 2016年第12期8卷 703-718页

作者： Rajamma mathew Jing huang Joseph m Wu John T Fallon michael h Gewitz Department of Physiology New York Medical College Section of Pediatric Cardiology New York Medical College Department of Biochemistry and molecular Biology New York Medical College Department of Pathology New York Medical College

Pulmonary hypertension(Ph),a serious disorder with a high morbidity and mortality rate,is known to occur in a number of unrelated systemic *** hematological disorders such as sickle cell disease,thalassemia and myeloproliferative diseases develop Ph which worsens the *** oxidant injury and vascular inflammation cause endothelial damage and *** vascular endothelial damage/dysfunction is an early event in Ph resulting in the loss of vascular reactivity,activation of proliferative and antiapoptotic pathways leading to vascular remodeling,elevated pulmonary artery pressure,right ventricular hypertrophy and premature *** observed in hematological disorders leads to free hemoglobin which rapidly scavenges nitric oxide(NO),limiting its bioavailability,and leading to endothelial *** addition,hemolysis releases arginase into the circulation which converts L-arginine to ornithine,thus bypassing NO ***,treatments for hematological disorders such as immunosuppressive therapy,splenectomy,bone marrow transplantation,and radiation have been shown to contribute to the development of *** studies have shown deregulated iron homeostasis in patients with cardiopulmonary diseases including pulmonary arterial hypertension(PAh).Several studies have reported low iron levels in patients with idiopathic PAh,and iron deficiency is an important risk *** article reviews Ph associated with hematological disorders and its mechanism:and iron homeostasis and its relevance to Ph.

关键词： Anemia hemolysis Iron homeostasis myelofibrosis Pulmonary hypertension

Impact Thickness on Structural and Electrical Characterization of Nickel Phthalocyanine Thin Films

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Advances in materials Physics and Chemistry 2019年第7期9卷 123-132页

作者： Eman m. Nasir mohammed T. hussein Addnan h. Al-Aarajiy Department of Physics College of Science University of Baghdad Baghdad Iraq Department of Physics College of Science University of Babylon Babylon Iraq

Thin films of Nickel Phthalocyanine have been prepared by evaporation technique for (50 - 350 nm) of thickness. XRD studies show that the thin films have single crystalline structure for low thicknesses with (100) orientation and the crystallite size increased with increased thickness. Also from the AFm technique for NiPc films, the roughness was determined and the grain size increases with increasing of thickness from except at thickness 350 nm. The studies of electrical properties, morphology and orientations of the crystallites are important to understand and predict the nature of the films and essential for their successful applications in solar cell and sensors. The electrical properties of these films were studied with different thickness, NiPc has three activation energy. Carrier’s concentration and mobility was calculated. hall measurements showed that all the films are p-type.

关键词： Nickel Phthalocyanine Vacuum Evaporation XRD AFm morphology Thin Film Electrical Properties

Novel Optimized Cross-Layer Design with maximum Weighted Capacity Based Resource Allocation for AmC/hARQ Wireless Networks

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Wireless Engineering and Technology 2013年第2期4卷 77-86页

作者： Reham A. El-mayet hesham m. El-Badawy Salwa h. Elramly Electronic and Communication Department Ain Shams University Cairo Egypt National Telecommunication Institute Cairo Egypt

To provide quality-of service (QoS) guarantees for heterogeneous applications, most recent wireless communications technologies and standards combine the error-correcting capability of hybrid automatic repeat request (hARQ) schemes at the data link layer (DLL) with the adaptation ability of the adaptive modulation and coding (AmC) modes at the physical layer (PhY) layer. This paper aims to investigate the aggregated system capacity as well as the breakdown of this capacity for different ACm modes in each hARQ scheme. This investigation was done by using maximum weighted capacity (mWC) resource allocation at the PhY layer in conjunction with a novel packet error rate (PER)-based scheduling at the medium access control (mAC) layer. As a result, the dominant AmC mode corresponding to channel SNR was available.

关键词： AmC Cross-Layer Design hARQ Nakagami-m Fading Channel QoS

Volume Change of the Random Coil to Folded Conformational Transition of <i>Thermomyces</i><i>lanuginosus</i>Xylanase at 24&#176C and ph = 7.0 via Application of the Clausius-Clapeyron Equation

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Journal of Biophysical Chemistry 2014年第4期5卷 134-142页

作者： heather N. h. Wilks Tara m. Arrington Billy mark Britt Department of Chemistry and Biochemistry Texas Woman’s University Denton Texas USA

A partial phase diagram characterizing the conformational change that occurs in Thermomyces lanuginosus xylanase as it is slowly heated in 150 mm sodium phosphate (ph = 7.0) has been con-structed from slow-scan-rate differential scanning calorimetry measurements. The Clausius-Clapeyron equation was applied to determine an associated volume change of -205 L·mol-1 at 24°C, the equilibrium transition temperature at 1.0 atm pressure. This value is in excellent agreement with that predicted using a previously published [1] empirical equation for calculating the hydro-dynamic radius if the transition is regarded as from a random coil to a functional, folded state and with the assumption that the hydrodynamic radius is a good approximation of the true random coil radius. The existence of a low-temperature random coil is confirmed by circular dichroism and dynamic light scattering measurements. Thus, at 24°C and 1.0 atm pressure the enzyme appears to fold from a random coil to a functional, folded form as it is slowly heated.

关键词： Clausius-Clapeyron Conformational Change Slow-Scan-Rate Differential Scanning Calorimetry Thermomyces lanuginosus Xylanase Volume Change

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东干的妇女——利益和命运

西北民族研究 2003年第4期 165-175页

作者： m·h·万斯瓦诺娃何群不详中央民族大学民族学社会学研究院在读博士研究生北京100081

本文作为专著的一章,以整个东干社会为背景,通过对几代东干妇女个人生活史的研究,展示了东干妇女社会生活变迁场景,赞美了她们对民族社会的卓越贡献.

关键词：《东干——人和命运》妇女生活变迁民族文化

Structural Origin and Energy Transfer Processes of 1.8μm Emission in Tm3+ Doped Germanate Glasses

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Structural Origin and Energy Transfer Processes of 1.8μm Em...

ThE EFFECT OF BORON TREATmENT ON ThE hYDROGEN ATTACK BEhAVIOR 0F 1.25Cr-0.5mo STEELS

第七届全国稀土发光材料学术研讨会

作者： Rongrong Xu~(1,2) Lili hu~1 Junjie Zhang~(1*) (1 Key Laboratory of materials for high Power Lasers, Shanghai Institute of Optics and Fine mechanics,Chinese Academy of Sciences,Shanghai 201800, People’s Republic of China) (2 Graduate School of Chinese Academy of Sciences, Beijing 100039,People’s Republic of China)

A detailed characterization of structural analysis and energy transfer(ET) process in Tm doped germanate glasses has been *** thermal stability and Raman spectroscopic analysis of the host glass structure has been *** was observed that replacing GeO by GaO resulted in decreasing of glass transition temperature and largest phonon *** concentration of GaO will decrease the density of cross-linking of the germanate glass *** weaker Ga-0 bonds result in lower phonon *** influence of the concentrations of GaO and the glass structure on the ET has also been *** extended overlap integral method is used to calculate the microparameter of the energy transfer and the critical *** results show that the transference Tm→Tm(h,h→h, h) energy migration is not phonon dependent in the quasiresonant processes,while the cross relaxation Tm→Tm(h,h→F,F) is a multiphonon mechanism dominated by one-phonon creation(～96%).It is demonstrated that the stretching frequencies and the ET processes become lower when increasing the concentration of GaO.

关键词： Tm3+ Germanate glass Emission properties Energy transfer

来源： cnki会议评论

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Acta metallurgica Sinica(English Letters) 1997年第3期10卷 233-238页

作者： X.h Luo T.J. Su C.G Fan Y Y Liand CX Shi(Institute of metal Research, Chinese Academy of Sciences, Shenyang 110015, China)X Chen and A.m Guo (Iron & Steel Research Institute, Wuhan Iron & Steel (Group) Company, Wuhan 430083, China) Inst of metal Research Chinese Acad of Sciences Shenyang China

1.25Cr-0.5mo steels with different Ti-B or Al-B treatment were exposed in 18 mPa hydrogen atmosphere at 480℃ fo f 100, 500 and 1000 h respectively. Tensile and bend properties of steels before and after hydrogen changing were tested. The results show that the different mechanical properties of the steels with different B content have different responses to high temperature high pressure hydrogen charging *** hydrogen changing, more loss of ductility can be found in the steel not treated with B than those in the steels treated with B. metallographic analyses indicated that decarburization occurred in all the steels. Furthermore, many methane bubbles were found by SEm analysis in the surface decarburization layer in the steel without B,while only a few bubbles, the number and size of which decreased with increasing B content, were found in steels with B treatment. In addition, hydrogen determination results manifested that after being exposed in hydrogen atmosphere the steel containing no B had higher hydrogen content than that of steels containing B. All this suggests that B treatment improved the hA resistance of 1.25Cgr-0.5mo steel, and the more B the steel contained the more perceptible the effect.

关键词： boron hydrogen attack Cr-mo steel low alloy steel

长链非编码RNA RmRP通过JAK2/STAT3信号通路增强胶质瘤细胞对替莫唑胺敏感性的机制研究

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中国临床药理学杂志 2018年第19期34卷 2320-2323页

作者：马飞李令兴李琳姜志平高培平泰安市中心医院静脉用药调配中心山东泰安271000 泰安市中心医院心内科山东泰安271000

目的探讨长链非编码RNA RmRP(lncRNA-RmRP)对胶质瘤替莫唑胺(TmZ)耐药的影响,并检测lncRNA-RmRP在胶质瘤细胞系(U87、U118)TmZ耐药细胞株(U87TR、U118TR)和原发胶质瘤组织、复发胶质瘤组织中的表达情况。方法用实时荧光定量聚合酶链式反... 详细信息

目的探讨长链非编码RNA RmRP(lncRNA-RmRP)对胶质瘤替莫唑胺(TmZ)耐药的影响,并检测lncRNA-RmRP在胶质瘤细胞系(U87、U118)TmZ耐药细胞株(U87TR、U118TR)和原发胶质瘤组织、复发胶质瘤组织中的表达情况。方法用实时荧光定量聚合酶链式反应(RT-q PCR)检测lncRNA-RmRP在U87、U87TR、U118、U118TR和胶质瘤组织、复发胶质瘤组织中的表达情况。U87TR、U118TR分别转染lncRNA-RmRP,并分为U87TR-RmRP组、U87TRNC组、U118TR-RmRP组和U118TR-NC组。用CCK-8方法检测400μmol·L^(-1)TmZ处理0,24,48,72,96 h后,U87、U87TR、U118、U118TR细胞的活力。用Western Blotting检测JAK2/STAT3相关蛋白的表达。结果 LncRNARmRP在U87、U87TR中表达量分别为(1.03±0.21)和(0.12±0.07),在U118、U118TR中表达量分别为(1.07±0.32)和(0.43±0.15),在复发胶质瘤组织和原发胶质瘤组织中表达量分别为(1.36±0.78)和(3.41±1.61),差异均有统计学意义(均Pmol·L^(-1),U118和U118TR的IC_(50)分别为(100.00±10.00)和(233.30±15.28)μmol·L^(-1),差异均有统计学意义(均PmRP和U87TR-NC的细胞增殖力分别为(2.18±0.14)和(4.36±0.13),U118TR-RmRP和U118TR-NC的细胞增殖力分别为(3.25±0.21)和(4.29±0.11),差异均有统计学意义(均PmRP组和U87TR-NC组的TmZ IC_(50)分别为(142.30±6.81)和(283.30±15.28)μmol·L^(-1),U118TR-RmRP组和U118TR-NC组的TmZ IC_(50)分别为(189.70±16.01)和(300.30±10.02)μmol·L^(-1),差异均有统计学意义(均PmRP组和U87TR-NC组的p-JAK2分别为(1.02±0.23)和(0.49±0.13),p-STAT3分别为(1.02±0.0.21)和(0.28±0.07),差异均有统计学意义(均PmRP和U87TR-NC组的p-JAK2分别为(1.00±0.13)和(0.29±0.04),p-STAT3分别为(1.09±0.27)和(0.36±0.04),差异均有统计学意义(均PmRP通过JAK2/STAT3信号通路增强胶质瘤细胞对TmZ敏感性。

关键词：替莫唑胺长链非编码RNA RmRP 胶质瘤耐药性

A theoretical study on different cluster configurations of the ~9Be nucleus by using a simple cluster model

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Nuclear Science and Techniques 2017年第6期28卷 179-189页

作者： m.Aygun Z.Aygun Department of Physics Bitlis Eren University Vocational School of Technical Sciences Bitlis Eren University

In this study,a comprehensive investigation on different cluster configurations of the ~9Be nucleus is performed with a simple cluster *** this goal,the elastic scattering angular distributions of ~9Be by ^(27)A1,^(28)Si,^(64)Zn,^(144)Sm,^(208)Pb,and ^(209)Bi target nuclei are reanalyzed for α + α + n,d + ~7Li,~3h + ~6Li,~3he + ~6he and n + ~8Be cluster configurations of the ~9Be projectile within the framework of the optical *** theoretical results are compared with each other as well as the experimental *** results provide an opportunity for a test of different cluster configurations in explaining the elastic scattering of^9Be nucleus.

关键词： Cluster structure Optical model Double folding model Elastic scattering