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Neutron Scattering Studies on Proteasome Component

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Neutron Scattering Studies on Proteasome Component

作者： m.sugiyama Y.morimoto Research Reactor Institute Kyoto University

INTRODUCTION:mammals have defensive systems in their safety *** of typical examples is a proteasome -ubiquitin *** such a system,there are two main protein complexes:20S proteasome,which is known as a degrading factory for intracellular proteins, and its activator *** of foreign substances is a trigger to produce Proteasome Activator 28(PA28) induced by an interferonγ,and then the 20S proteasome makes a complex with two *** target protein is specified by PA28 and degraded by the 20S proteasome.

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Structural Investigation of the 20S Proteasome and Its Related Particles

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Structural Investigation of the 20S Proteasome and Its Relat...

作者： Y.morimoto K.Nishio m.sugiyama Research Reactor Institute Kyoto University

INTRODUCTION:Proteasomes(or multicatalytic protease complexes) are widely distributed in eukaryotes, ranging from human to *** higher eukaryotes,proteasomes are known to act as antigen-processing enzymes responsible for the generation of peptide ligands presented by major histocompatibility complex(mHC) class I *** have molecular masses of approximately 750 kDa and sedimentation coefficients of approximately *** are barrel-like particles formed

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Development of Analyzing method of Small-Angle Scattering for Size Distribution of Segregation Particles in metal Alloy

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Development of Analyzing Method of Small-Angle Scattering fo...

作者： m.sugiyama S.Kawabe K.mori K.Itoh T.Fukunaga Research Reactor Institute Kyoto University Graduate School of Engineering Kyoto University

INTRODUCTION:Small-angle scattering(SAS) is one of very powerful tools to analyze nano-scale structure. However,standard analysis methods,such as Guinier analysis,Ornstein-Zernike analysis and so on,give us average size of particles and/or average length of density fluctuation in an observed *** means that detailed particle shape,size distribution and position distribution are not obtained with the standard analyzing *** overcome the limitations in SAS,we are developing a

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Development of a High-Intensity Neutron monochromator

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Development of a High-Intensity Neutron Monochromator

作者： m.Furusaka N.Ishikawa m.Hino T.Sato Y.Okusawa F.Fujita A.Homma m.sugiyama Faculty of Engineering Hokkaido University

INTRODUCTION:Pyrolytic-Graphite(PG) is widely used as a high-integrated-reflectivity neutron monochromator. It is a very good monochromator material for moderate-resolution ***,applications such as small-angle neutron scattering(SANS) or reflectometer instruments need a wavelength-band of more than a few%,possibly about 10%.In such cases,not only unreasonably high mosaicity of more than 2 degrees is required,but it must also be coupled with incident beam that has extremely high beam-divergence of about

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含有回收材料的GRC的性能

混凝土世界 2008年第Z1期 77-86页

作者： S.NISHIBORI Y.TAKEUCHI m.sugiyama m.KOBAYASHI 刁桂枝日本电气硝子有限公司

由于对环境的关注和废料的处理问题,近些年对工业废料进行了积极的回收。回收废料作为混合材被广泛应用在GRC混凝土中。本文对使用了工业废料混合材的GRC的基本物理性能和耐久性所进行了研究。我们的结论是:粉煤灰、矿渣和硅灰的使用可... 详细信息

由于对环境的关注和废料的处理问题,近些年对工业废料进行了积极的回收。回收废料作为混合材被广泛应用在GRC混凝土中。本文对使用了工业废料混合材的GRC的基本物理性能和耐久性所进行了研究。我们的结论是:粉煤灰、矿渣和硅灰的使用可以提高GRC的耐久性。在这些结论的基础上,提出将耐久性好的GRC配合比与回收废料结合在一起。经加速老化试样的抗折强度相当于暴露在日本室外10年时间的试件的强度,高于最初的强度,等于传统GRC的强度。由于火山灰反应消耗了基体中的Ca(OH)_2,分别通过热分析和X射线衍射分析,在加速老化的含有矿渣和硅灰的砂浆中没有发现Ca(OH)_2。

关键词：生态水泥粉煤灰玻璃纤维粒化高炉矿渣 GRC 火山灰反应回收材料硅灰.

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具有图象放大、偏移和旋转功能的微通道空间光调制器

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应用光学 1990年第2期11卷 27-31,26页

作者： Tsutomu Hara K.Shinoda T.Kato m.sugiyama Y.Suzuki 焦冰(译)

具有写入正、负电荷功能的微通道空间光调制器已经研制出来,它还具有图象放大、偏移和旋转的特殊功能。此器件能实现图象求导和拉普拉斯运算以及图象相加、相减和逻辑运算,从而促进了图形识别技术的进展。

关键词：空间光调制器微通道板图形识别技术旋转功能晶体表面图象处理非相干光聚焦电极擦除操作电荷分布

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5种低渗非离子碘对比剂的急性不良反应有何不同?

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国际医学放射学杂志 2010年第5期 496-496页

作者： T.Gomi m.Nagamoto m.Hasegawa A.Katoh m.sugiyama N.murata 陈柱 Department of Radiology Toho University Ohashi Medical Center

Nonlinear forced vibration in a subcritical regime of a porous functionally graded pipe conveying fluid with a retaining clip

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 101-122页

作者： m.GHOLAmI m.EFTEKHARI Department of mechanical Engineering Shahid Bahonar University of Kerman

This study examines the nonlinear behaviors of a clamped-clamped porous pipe made of a functionally graded material(FGm) that conveys fluids and is equipped with a retaining clip, focusing on primary resonance and subcritical dynamics. The nonlinear governing equations for the FGm pipe are derived by the extended Hamilton's principle, and subsequently discretized through the application of the Galerkin *** direct method of multi-scales is then used to solve the derived equations. A thorough analysis of various parameters, including the clip stiffness, the power-law index, the porosity, and the clip location, is conducted to gain a comprehensive understanding of the system's nonlinear dynamics. Through the analysis of the first natural frequency, the study highlights the influence of the flow velocity and the clip stiffness, while the comparisons with metallic pipes emphasize the role of FGm composition. The examination of the forced response curves reveals saddle-node bifurcations and their dependence on parameters such as the detuning parameter and the power-law index, offering valuable insights into the system's nonlinear resonant behavior. Furthermore, the frequency-response curves illustrate the hardening nonlinearities influenced by factors such as the porosity and the clip stiffness, revealing nuanced effects on the system response and resonance characteristics. This comprehensive analysis enhances the understanding of nonlinear behaviors in FGm porous pipes with a retaining clip, providing key insights for practical engineering applications in system design and optimization.

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Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

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