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Surface texture evaluation of additively manufactured metallic cellular scaffolds for acetabular implants using *** computed tomography

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Bio-Design and manufacturing 2019年第2期2卷 55-64页

作者： Shan Lou Luca pagani Wenhan Zeng muhammad U.Ghori Xiangqian Jiang Paul J.Scott EPSRC Future metrology Hub University of HuddersfieldQueensgateHuddersfield HD1 3DHUK Department of Pharmacy University of HuddersfieldQueensgateHuddersfield HD1 3DHUK

The surface topography of acetabular implants plays a key role in providing cell attachment and *** measurement and characterisation of the surface texture of the cellular scaffold layer on the acetabular cup are very difficult due to the 3D nature of scaffold *** is proposed to use X-ray computed tomography(XCT)to measure the surface texture of an electron beam melting-produced titanium acetabular *** surface texture of its cellular scaffold is evaluated using the newly developed 3D surface texture parameters,which allows surface characterisation on 3D triangular mesh *** commonly used height parameters,*** arithmetical mean height Sa,the root mean square height Sq,the skewness Ssk and the kurtosis Sku,are calculated from surface patches extracted from the XCT scanned triangular mesh *** addition,the surface peak density and pit density,which are more related to cell communication and proliferation,are estimated based on the 3D watershed *** Wolf pruning with an empirical threshold 12μm is used to control the over-segmentation.

关键词： Additive manufacturing Cellular scaffold Surface texture X-ray computed tomography

The CCD instrument background of the SmILE SXI

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Earth and Planetary Physics 2024年第1期8卷 15-24页

作者： m.W.J.Hubbard O.Hetherington D.J.Hall T.W.Buggey S.Parsons T.Arnold A.Holland C.pagani S.Sembay Centre for Electronic Imaging The Open UniversityMilton KeynesMK76AAUK X-ray and Observational Astronomy Group Department of Physics&AstronomyUniversity of LeicesterLE17RHUK

The ESA and CAS SmILE mission orbit is highly elliptical and will pass through multiple radiation *** Soft X-ray Imager(SXI)instrument aboard has a radiation shutter door designed to close when the surrounding radiation flux is *** shutter door will close when passing below an altitude threshold to protect against trapped particles in the Earth’s Van Allen ***,two radiation environments can be approximated based on the shutter door position:open and *** instrument background for the CCDs(Charge-Coupled Devices)that form the focal plane array of the SXI were evaluated for the two *** to the correlation of the space environment with the solar cycle,the solar minima and maxima,the background was also evaluated at these two *** results demonstrated that the highest instrument background will occur during solar minima due to the main contributing source being Galactic Cosmic Rays(GCRs).It was also found that the open background was highest for solar minima and that the closed background was highest during solar *** is due to the radiation shutter door acting as a scattering centre and the changes in the energy flux distribution of the GCRs between the two solar extremes.

关键词： instrument background X-ray astronomy space radiation

Top quark pair production at complete NLO accuracy with NNLO+NNLL′corrections in QCD

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Chinese Physics C 2020年第8期44卷 40-45页

作者： michałCzakon Andrea Ferroglia Alexander mitov Davide pagani Andrew S.Papanastasiou Benjamin D.Pecjak Darren J.Scott Ioannis Tsinikos Xing Wang Li Lin Yang marco Zaro Institut für Theoretische Teilchenphysik und Kosmologie RWTH Aachen UniversityD-52056 AachenGermany New York City College of Technology BrooklynNY 11201USA The Graduate School and University Center The City University of New YorkNew YorkNY 10016 USA Cavendish Laboratory University of CambridgeCB30HE CambridgeUK Technische Universität münchen James-Franck-Str.1D-85748 GarchingGermany Theory Group Deutsches Elektronen-Synchrotron(DESY)D-22607 HamburgGermany Institute for Particle Physics Phenomenology University of DurhamDH13LE DurhamUK Institute for Theoretical Physics University of AmsterdamScience Park 9041098 XH AmsterdamThe Netherlands Nikhef Theory GroupScience Park 1051098 XGAmsterdamThe Netherlands Theoretical Particle Physics Department of Astronomy and Theoretical PhysicsLund UniversitySölvegatan 14ASE-22362 LundSweden PRISmA+Cluster of Excellence Johannes Gutenberg UniversityD-55128 MainzGermany Zhejiang Institute of modern Physics Department of PhysicsZhejiang UniversityHangzhou 310027China INFN Sezione di MilanoVia Celoria 1620133 MilanoItaly

We describe predictions for top quark pair differential distributions at hadron colliders,by combining the next-to-next-to-leading order quantum chromodynamics calculations and next-to-leading order electroweak corrections with double resummation at the next-to-next-to-leading logarithmic accuracy of threshold logarithms and small-mass *** the best of our knowledge,this is the first study to present such a combination,which incorporates all known perturbative *** results are presented for the invariant-mass distribution,transverse-momentum distribution,and rapidity distributions.

关键词： top quark production QCD electroweak

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交感神经系统对充血性心力衰竭的作用

国外医学.心血管疾病分册 1983年第6期 331-332页

作者： malliani A pagani m 颜和昌

充血性心力衰竭似乎能够显著地影响控制心血管功能的神经机能,表现为副交感神经作用的减退和交感神经张力的亢进.文献记载,充血性心力衰竭者不论在休息或活动情况下,血浆中去甲肾上腺素的含量都有大幅度增高,而心脏本身组织却缺乏儿茶酚... 详细信息

充血性心力衰竭似乎能够显著地影响控制心血管功能的神经机能,表现为副交感神经作用的减退和交感神经张力的亢进.文献记载,充血性心力衰竭者不论在休息或活动情况下,血浆中去甲肾上腺素的含量都有大幅度增高,而心脏本身组织却缺乏儿茶酚胺.从人类和充血性心力衰竭的动物模型中也发现心肌细胞内的儿茶酚胺含量降低,而且交感神经所支配的血管反应性增高.与此相反,心脏迷走神经的传出冲动却减弱,由加压刺激所应有的反射性心率减慢作用明显降低.

关键词：充血性心力衰竭心脏副交感神经交感神经张力迷走神经传入纤维交感神经兴奋压力感受器血管舒缩神经系统

The Soft X-ray Imager(SXI)on the SmILE mission

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Earth and Planetary Physics 2024年第1期8卷 5-14页

作者： S.Sembay A.L.Alme D.Agnolon T.Arnold A.Beardmore A.Belén Balado margeli C.Bicknell C.Bouldin G.Branduardi-Raymont T.Crawford J.P.Breuer T.Buggey G.Butcher R.Canchal J.A.Carter A.Cheney Y.Collado-Vega H.Connor T.Crawford N.Eaton C.Feldman C.Forsyth T.Frantzen G.Galgóczi J.Garcia G.Y.Genov C.Gordillo H-P.Gröbelbauer m.Guedel Y.Guo m.Hailey D.Hall R.Hampson J.Hasiba O.Hetherington A.Holland S-Y.Hsieh m.W.J.Hubbard H.Jeszenszky m.Jones T.Kennedy K.Koch-mehrin S.Kögl S.Krucker K.D.Kuntz C.Lakin G.Laky O.Lylund A.martindale J.miguel mas Hesse R.Nakamura K.Oksavik N.Østgaard H.Ottacher R.Ottensamer C.pagani S.Parsons P.Patel J.Pearson G.Peikert F.S.Porter T.Pouliantis B.H.Qureshi W.Raab G.Randal A.m.Read N.m.m.Roque m.E.Rostad C.Runciman S.Sachdev A.Samsonov m.Soman D.Sibeck S.Smit J.Søndergaard R.Speight S.Stavland m.Steller TianRan Sun J.Thornhill W.Thomas K.Ullaland B.Walsh D.Walton C.Wang S.Yang School of Physics and Astronomy University of LeicesterLeicesterLE17RHUK Space Park Leicester University of LeicesterLeicesterLE17RHUK mullard Space Science Laboratory University College LondonDorkingRH56NTUK Centre for Electronic Imaging Open UniversityMilton KeynesMK76 AAUK Birkeland Centre for Space Science Department of Physics and TechnologyUniv.of BergenN-5007 BergenNorway University of Vienna A-1010 ViennaAustria Space Research Institute Austrian Academy of SciencesA-8042 GrazAustria National Institute of Aerospace Technology MadridSpain ESTEC European Space Agency2201 AZ NoordwijkNetherlands State Key Laboratory of Space Weather National Space Science CentreBeijing 100190China University of Applied Sciences and Arts Northwestern Switzerland CH-5210 WindischSwitzerland Koegl Space GmbH CH-8157 DielsdorfSwitzerland Space Acoustics GmbH CH-8157 DielsdorfSwitzerland Zurich University of Applied Sciences 8400 WinterhurSwitzerland Genov Solutions N-5172 LoddefjordNorway STm Engineering N-5165 LaksevagNorway John Hopkins University Applied Physics Laboratory MD 20723USA NASA/Goddard Space Flight Centre MD 20771USA Center for Space Physics Boston UniversityBostonMA 02215USA Department of Theoretical Physics and Astrophysics Masaryk University60177 BrnoCzech Republic Institute of Physics E¨otvo¨s Lor´and University1053 BudapestHungary Aerospace Information Research Institute Chinese Academy of SciencesBeijing 100045China Centro de Astrobiologia(CAB) CSIC-INTAMadridSpain

The Soft X-ray Imager(SXI)is part of the scientific payload of the Solar wind magnetosphere Ionosphere Link Explorer(SmILE)*** is a joint science mission between the European Space Agency(ESA)and the Chinese Academy of Sciences(CAS)and is due for launch in *** is a compact X-ray telescope with a wide field-of-view(FOV)capable of encompassing large portions of Earth’s magnetosphere from the vantage point of the SmILE *** is sensitive to the soft X-rays produced by the Solar Wind Charge eXchange(SWCX)process produced when heavy ions of solar wind origin interact with neutral particles in Earth’s *** provides a mechanism for boundary detection within the magnetosphere,such as the position of Earth’s magnetopause,because the solar wind heavy ions have a very low density in regions of closed magnetic field *** sensitivity of the SXI is such that it can potentially track movements of the magnetopause on timescales of a few minutes and the orbit of SmILE will enable such movements to be tracked for segments lasting many *** is led by the University of Leicester in the United Kingdom(UK)with collaborating organisations on hardware,software and science support within the UK,Europe,China and the United States.

关键词： Soft X-ray Imaging micropore optics large area CCD

慢性直立耐受不良患者压力反射及自主神经对下肢负压吸引的反应均发生改变

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世界核心医学期刊文摘（心脏病学分册） 2005年第2期1卷 62-62页

作者： Lucini D. Furlan R. Villa P. m. pagani 杜媛 medicina I Ospedale’L. Sacco’ Universitàdi Milano Via G. B. Grassi 74 20157 Milano Italy Dr.

Background: Chronic orthostatic intolerance(COI) is a common and disabling aut onomic syndrome of unclear pathophysiology. We tested the hypothesis that barore flex and autonomic responses to graded lower body suction (LBNP, up to 40mmHg) could be altered in COI patients. methods: Electrocardiogram (ECG), non invasi ve arterial blood pressure and respiratory activity were measured during progres sive LBNP (seven patients and seven volunteers). Lumped arterial barore flex se nsitivity (a index), and its arterial and cardiopulmonary components,were assess ed by multivariate closed loop analysis of RR interval and systolic arterial pr essure(SAP) spontaneous variabilities and respiration. monovariate spectral anal ysis of RR interval and SAP variability provided markers of autonomic regulation of the sinoatrial(SA) node and of vascular sympathetic modulation. Results: Sim ilar reductions in overall and cardiopulmonary baroreflex gain were observed in both groups in response to graded LBNP. In contrast, only controls demonstrated a selective increase in arterial baroreflex sensitivity, at low grade LBNP. Cle ar increases in the low frequency component of RR interval variability (LFRR) [ and decreases in the high frequency component of RR interval variability (HFRR) , both in normalized units]were observed in controls with graded LBNP, while in s ignificant changes occurred in COI patients, who showed, conversely, exaggerated sympathetic vasomotor responses [as assessed by the low frequency component of SAP variability(LFSAP)]. Conclusions: Patients with chronic orthostatic intoler a nce show distinct signs of altered baroreflex and autonomic regulation of the SA node and of the vasculature in response to graded LBNP.

关键词：下肢负压压力反射动脉收缩压血压测量变异度窦房结功能失常病理生理学血管反应多变量

区域性而不是全脑性脑损伤导致多发性硬化的疲劳

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国际医学放射学杂志 2015年第1期 68-68页

作者： m.A.Rocca L.Parisi E.pagani m.Copetti m.Rodegher m.Filippi Neuroimaging Research Unit CERMACSan Raffaele Scientific InstituteVita-Salute San Raffaele University

目的使用mR成像和先进的分析评估正常白质(NAWm)和灰质(Gm)损伤、全脑与区域性损伤、萎缩与微结构异常病变在多发性硬化(mS)疲劳发病机制中的作用。材

关键词：多发性硬化灰质全脑异常病变发病机制扩散张量白质髓质脑损伤区域性

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多发硬化病人的丘脑损伤和长期残障进展

国际医学放射学杂志 2011年第1期34卷 75-页

作者： m.A.Rocca S.mesaros E.pagani m.P.Sormani G.Comi m.Filippi 李睿 Neuroimaging Research Unit Institute of Experimental NeurologyDivision of NeuroscienceScientific Institute and University Hospital San Raffaele

目的评估磁化转移(mT)mR成像所显示初期丘脑萎缩和异常及其后12个月的变化,以预测一组相对大样本的间断发作型多发硬化(mS)

关键词：多发硬化 mS 丘脑萎缩病人残障

多发性硬化:认知康复效应在结构功能mRI上的测量的探索性研究

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国际医学放射学杂志 2012年第3期 274-274页

作者： m.Filippi G.Riccitelli F.mattioli R.Capra C.Stampatori E.pagani 李金芳 Neuroimaging Research Unit Institute of Experimental NeurologyDepartment of NeurologyDivision of Neuroscienceand Scientific Institute and Vita-Salute UniversityHospital San RaffaeleVia Olgettina 6020132 MilanItaly

目的应用神经心理学评估方法和结构及功能mRI技术评价临床稳定的复发缓解(relapsing-remitting,RR)型多发性硬化(multiple sclerosis,mS)病人认知康复后的脑变化。材料与方法本研究通过机构审查委员会的许可。每例病人签署知情同意书。... 详细信息

目的应用神经心理学评估方法和结构及功能mRI技术评价临床稳定的复发缓解(relapsing-remitting,RR)型多发性硬化(multiple sclerosis,mS)病人认知康复后的脑变化。材料与方法本研究通过机构审查委员会的许可。每例病人签署知情同意书。将20例具有认知缺陷的RRmS病人随

关键词：认知康复病人 mS RR 神经心理学 mRI