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Discovery of the New Isotope^(251)Lr

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Imp & HIRFL Annual Report 2022年第1期 38-38页

作者： Huang Tianheng D.Seweryniak B.B.Back p.Bender m.p.carpenter p.Chowdhury R.m.Clark p.Copp X.-T.He R.D.Herzberg D.Ho H.Jayatissa T.L.Khoo F.G.Kondev G.morgan Ch.morse A.Korichi T.Lauritsen C.muller-Gatermann D.potterveld W.Reviol A.Rogers S.Saha G.Savard K.Sharma S.Stolze S.Waniganeththi G.Wilson J.Wu Y.-F.Xu S.Zhu Institute of modern physics Chinese Academy of SciencesLanzhou 730000China Argonne National Laboratory ArgonneIL 60439USA University of massachusetts LowellMA 01854USA Lawrence Berkeley National Laboratory BerkeleyCA 94720USA College of materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016China University of Liverpool LiverpoolUK Louisiana State University Baton RougeLA 70803USA IJCLab IN2P3-CNRSFrance Brookhaven National Laboratory UptonNY 11973USA

The products of the^(203,205)Ti(^(50)Ti,2n)fusion-evaporation reactions were studied by using the recently commissioned Argonne Gas-Filled Analyzer(AGFA)at Argonne National Laboratory.

关键词： 2n Argonne

Geophysical Surveys over Karst Recharge Features,Illinois,USA

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Acta Geologica Sinica(English Edition) 2001年第3期75卷 249-253页

作者： philip J.carpenter Shawkat AHmED Department of Geology and Environmental Geosciences 312 Davis Hall Northern Illinois University DeKalb Illinois USADepartment of Geology and Environmental Geosciences 312 Davis Hall Northern Illinois University DeKalb Illinois USA

Karst aquifers supply a significant fraction of the world's drinking water. These types of aquifers are alsohighly susceptible to pollution from the surface with recharge usually occurring through fractures and solution openings at the bedrock surface. Thickness of the protective soil cover, macropores and openings within the soil cover, and the nature of the weathered bedrock surface all influence infiltration. Recharge openings at the bedrock surface, however, are often covered by unconsolidated sediments, resulting in the inadvertent placement of landfills, unregulated dump sites, tailing piles, waste lagoons and septic systems over recharge zones. In these settings surface geophysical surveys, calibrated by a few soil cores, could be employed to identify these recharge openings, and qualitatively assess the protection afforded by the soil cover. In a test of this hypothesis, geophysical measurements accurately predicted the thickness of unconsolidated deposits overlying karstic dolomite at a site about 100 km south of Chicago, Illinois. Zones of elevated electrical conductivity and high ground-penetrating radar (GpR) attenuation within the sediments coincided with subcropping solutionally-enlarged hydraulically active bedrock fractures. These fractures extend to over 12-m depth, as shown by 2-D inverted resistivity sections and soil coring. Anomalous electromagnetic (Em) conductivity and GpR response may be due to higher soil moisture above these enlarged fractures. An epikarstal conduit at 2.5-m depth was directly identified through a GpR survey. These results suggest that surface geophysical surveys are a viable tool for assessing the susceptibility of shallow karst aquifers to contamination.

关键词： karst geophysics epikarst soil pipes recharge infiltration sinkholes

Nutritional epigenetics education improves diet and attitude of parents of children with autism or attention deficit/hyperactivity disorder

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World Journal of psychiatry 2024年第1期14卷 159-178页

作者： Renee J Dufault Katherine m Adler David O carpenter Steven G Gilbert Raquel A Crider College of Graduate Health Studies A.T.Still UniversityKirksvilleMO 63501United States Department of Research Food Ingredient and Health Research InstituteNaalehuHI 96772United States Department of Health Sciences University of New HavenWest HavenCT 06516United States Institute for Health and the Environment School of Public HealthState University of New YorkAlbanyNY 12222United States Department of Research Institute of Neurotoxicology and Neurological DisordersSeattleWA 98105United States Department of Statistics Food Ingredient and Health Research InstituteNaalehuHI 96772United States

BACKGROUND Unhealthy maternal diet leads to heavy metal exposures from the consumption of ultra-processed foods that may impact gene behavior across generations,creating conditions for the neurodevelopmental disorders known as autism and attention deficit/hyperactivity disorder(ADHD).Children with these disorders have difficulty metabolizing and excreting heavy metals from their bloodstream,and the severity of their symptoms correlates with the heavy metal levels measured in their *** may play a key role in helping parents reduce their ultra-processed food and dietary heavy metal intake by providing access to effective nutritional epigenetics *** To test the efficacy of nutritional epigenetics instruction in reducing parental ultra-processed food *** The study utilized a semi-randomized test and control group pretest-posttest pilot study design with participants recruited from parents having a learning-disabled child with autism or ***-two parents who met the inclusion criteria were randomly selected to serve in the test(n=11)or control(n=11)*** test group participated in the six-week online nutritional epigenetics tutorial,while the control group did *** efficacy of the nutritional epigenetics instruction was determined by measuring changes in parent diet and attitude using data derived from an online diet survey administered to the participants during the pre and post intervention *** intake scores were derived for both ultra-processed and whole/organic *** sample t-tests were conducted to determine any differences in mean diet scores within each *** There was a significant difference in the diet scores of the test group between the pre-and post-intervention *** parents in the test group significantly reduced their intake of ultra-processed foods with a preintervention diet score of 70(mean=5.385,SD=2.534)and a post-intervention diet score of 113(mean=8.692,SD=1.750)and the

关键词： Epigenomics parenteral nutrition Autism Attention deficit/hyperactivity disorder Ultra-processed foods Heavy metals

High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular vesicles that modulate microglia

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Bioactive materials 2024年第7期37卷 153-171页

作者： Andrew m.Larey Thomas m.Spoerer Kanupriya R.Daga maria G.morfin Hannah m.Hynds Jana carpenter Kelly m.Hines Ross A.marklein School of Chemical Materialsand Biomedical EngineeringUniversity of GeorgiaAthensGAUSA Regenerative Bioscience Center University of GeorgiaAthensGAUSA Department of Chemistry University of GeorgiaAthensGAUSA

Due to their immunomodulatory function,mesenchymal stromal cells(mSCs)are a promising therapeutic with the potential to treat neuroinflammation associated with neurodegenerative *** function is mediated by secreted extracellular vesicles(mSC-EVs).Despite established safety,mSC clinical translation has been unsuccessful due to inconsistent clinical outcomes resulting from functional *** approaches to mitigate functional heterogeneity include‘priming’mSCs with inflammatory signals to enhance ***,comprehensive evaluation of priming and its effects on mSC-EV function has not been ***,clinical translation of mSC-EV therapies requires significant manufacturing scale-up,yet few studies have investigated the effects of priming in *** mSC morphology has been shown to predict their immunomodulatory function,we screened mSC morphological response to an array of priming signals and evaluated mSC-EV identity and potency in response to priming in flasks and *** identified unique priming conditions corresponding to distinct *** conditions demonstrated a range of mSC-EV preparation quality and lipidome,allowing us to discover a novel mSC-EV manufacturing condition,as well as gain insight into potential mechanisms of mSC-EV microglia *** novel screening approach and application of priming to mSC-EV bioreactor manufacturing informs refinement of larger-scale manufacturing and enhancement of mSC-EV function.

关键词： mesenchymal stromal cell High throughput screening Extracellular vesicle Bioreactor microglia Lipidomics

Disagreement in middle ear volume estimation between tympanometry and three-dimensional volume reconstruction in the context of tympanic membrane perforation

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Journal of Otology 2017年第2期12卷 74-79页

作者： David J.carpenter Debara L.Tucci David m.Kaylie Dennis O.Frank-Ito Division of Head and Neck Surgery&Communication Sciences Department of SurgeryDuke University Medical CenterDurhamNCUSA Computational Biology&Bioinformatics phD program Duke UniversityDurhamNCUSA Department of mechanical Engineering and materials Science Duke UniversityDurhamNCUSA

Introduction: middle ear volume(mEV) is a clinically relevant parameter across middle ear diseases. mEV values between these techniques have never before been tested for agreement in ears with perforated tympanic membranes(Tms).methods: middle ears were identified from 36 patients ranging 18-89 years of age with Tm perforations who underwent tympanometry and temporal bone computed tomography(CT) between 2005 and 2015. mEVs calculated by both tympanometry and three-dimensional volume reconstruction(3DVR) were analyzed for agreement using Bland Altman plots. The differences between tympanometric and 3DVR mEV values for each given middle ear were characterized across mEV quartiles(1= smallest; 4= largest) and across increasing states of middle ear disease using Kruskale Wallis and Wilcoxon testing with Bonferroni ***: Bland Altman plots demonstrated significant disagreement between mEV measurement techniques. Differences between tympanometric(T) and 3DVR mEV values were significantly greater with increasing average(i.e.(Tt3DVR)/2)) mEV per linear regression(p monstrated between fourth and first average mEV quartiles(p= 0.0024), fourth and second quartiles(p= 0.0024), third and first quartiles(p= 0.0048), and third and second quartiles(p= 0.048). Absolute mEV difference was not significantly different across varying states of middle ear disease(p= 0.44).Conclusion: Statistically and clinically significant disagreement was demonstrated between tympanometric and 3DVR mEV values. Studies that vary in mEV estimation techniques may be expected to demonstrate significantly different results. These preliminary results suggest that clinicians should endeavor to seek further confirmation when interpreting high tympanometric mEV values.

关键词： middle ear volume Tympanometry Three-dimensional volume reconstruction Tympanic membrane perforation

The anatomic determinants of conductive hearing loss secondary to tympanic membrane perforation

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Journal of Otology 2017年第3期12卷 125-131页

作者： David J.carpenter Debara L.Tucci David m.Kaylie Dennis O.Frank-Ito Division of Head and Neck Surgery & Communication Sciences Department of Surgery Duke University Medical Center Durham NC USA Computational Biology & Bioinformatics phD program Duke University Durham NC USA Department of mechanical Engineering and materials Science Duke University Durham NC USA

Objectives: Recent studies have introduced middle ear volume(mEV) as a novel determinant of perforation-induced conductive hearing loss(CHL) in a mechanism driven by trans-tympanic membrane pressure differences. The primary aims of this preliminary report are to: 1) correlate CHL with perforation size; 2) describe the relationship between CHL and mEV; and 3) compare CHL across a range of cholesteatoma ***: A retrospective pilot study was performed in 31 subjects with audiometry indicative of conductive hearing loss, temporal bone CT scans,and no prior middle ear surgery. perforation size and mEV were analyzed with respect to CHL in a cohort of 10 perforated ears with no cholesteatoma. CHLs were compared in 3 groups defined by extent of cholesteatoma ***: Ears with large and small perforations showed mean ABG values of 32.0 ± 15.7 dB and 16.0 ± 16.4 dB, respectively. A direct relationship was observed between mEV and CHL for ears with large perforations across all frequencies, whereas this relationship for small perforations was frequency-dependent. Finally, a statistically significant increase in CHL was found across ears with increasing cholesteatoma involvement at 1000 Hz(X^2(2) = 9.786, p = 0.008),2000 Hz(x^2(2) = 8.455, p = 0.015),and 4000 Hz(x^2(2)= 8.253, p = 0.016).Conclusions: These pilot data suggest that greater perforation-induced conductive hearing losses may be associated with larger perforation sizes and cholesteatoma. The correlation between mEV and CHL may require additional study.

关键词： perforation-induced hearing loss Conductive hearing loss middle ear volume Three-dimensional volume reconstruction

Development of Low Carbon microalloyed High Strength Ultra-Thin Cast Strip products produced by the Castrip~ process With Excellent Strength-Ductility properties

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Journal of Iron and Steel Research International 2011年第S1期18卷 846-850页

作者： C.R. Killmore K.R. carpenter H.R. Kaul D.G. Edelman J.m. Cairney S.p. Ringer J.G. Williams p.C. Campbell W.N. Blejde BlueScope Steel Five Islands Road Pt Kembla 2500 Australia Nucor Steel Indiana 4537 S. Nucor Rd. Crawfordsville IN 47933 USA Australian Centre for microscopy and microanalysis University of Sydney NSW 2006 Australia Castrip LLC1915 Rexford Rd. Charlotte NC 28211 USA

The CASTRIp* process produces a range of high strength Ultra-thin Cast Strip (UCS) products (380-550 mpa) in thicknesses between 0.9 mm and 1.5 mm, which is very challenging to produce via conventional hot and cold rolled processing routes. The twin roll CASTRIp process fully exploits the hardenability and strengthening potential of Nb in a low C-mn-Nb-V microalloyed steel type. Significant microstructural strengthening from solute Nb was obtained, even at low microalloying levels, as well as modest mn additions, through enhancing the hardenability and further strengthening was obtained in coated products by exploiting age hardening during processing on a continuous hot dip galvanising line. Atom probe tomography and TEm determined that Nb was retained in solid solution and subsequent age hardening resulted from the formation of Nb and V rich nanosized particles. Age hardening was achieved without loss of ductility producing galvanised strip with an excellent strength-ductility combination (Y.S. >600 mpa, T.E. >10%).

关键词： strip casting microalloying niobium ntom probe tomography age hardening high strength CASTRIp process

Nature-inspired chiral metasurfaces for circular polarization detection and full-Stokes polarimetric measurements

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Light(Science & Applications) 2019年第1期8卷 494-504页

作者： Ali Basiri Xiahui Chen Jing Bai pouya Amrollahi Joe carpenter Zachary Holman Chao Wang Yu Yao School of Electrical Computer and Energy EngineeringArizona State UniversityTempeAZ 85281USA Centre for photonic Innovation Arizona State UniversityTempeAZ 85281USA Biodesign Centre for molecular Design&Biomimetics Arizona State UniversityTempeAZ 85281USA

The manipulation and characterization of light polarization states are essential for many applications in quantum communication and computing,spectroscopy,bioinspired navigation,and *** metamaterials and metasurfaces facilitate ultracompact devices for circularly polarized light generation,manipulation,and ***,we report bioinspired chiral metasurfaces with both strong chiral optical effects and low insertion *** experimentally demonstrated submicron-thick circularly polarized light filters with peak extinction ratios up to 35 and maximum transmission efficiencies close to 80% at near-infrared wavelengths(the best operational wavelengths can be engineered in the range of 1.3-1.6μm).We also monolithically integrated the microscale circular polarization filters with linear polarization filters to perform full-Stokes polarimetric measurements of light with arbitrary polarization *** the advantages of easy on-chip integration,ultracompact footprints,scalability,and broad wavelength coverage,our designs hold great promise for facilitating chip-integrated polarimeters and polarimetric imaging systems for quantum-based optical computing and information processing,circular dichroism spectroscopy,biomedical diagnosis,and remote sensing applications.

关键词： polarization circular polar

Hydrogen diffusion in clinopyroxene: dehydration experiments

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Science China Earth Sciences 2000年第6期43卷 561-568页

作者：夏群科陈道公 S.carpenter 支霞臣王汝成程昊 Department of Earth and Space Sciences University of Science and Technology of China Hefei 230026 China Department of Geosciences The Pennsylvania State University PA 16082 USA State Key Laboratory of mineral Deposits Nanjing University Nanjing 210093 China

Hydrogen diffusivity of one clinopyroxene megacryst from Nüshan, eastern China parallel to [001]* crystallographic direction was measured by high-temperature sequential dehydration experiments at 950üC and 850üC, which was (6.5ü1.5)×10-12(m2/s) and (1.8×0.7)×10-12(m2/s) respectively. From these results and the previous published data, it seems that the correlation between hydrogen diffusivity and Fe content suggested by Dyar et al. (1996) possibly does not exist. Clinopyroxene megacrysts from alkali basalts appear to be possible reliable samples for the study of the water evolution and hydrogen isotope compositions of the upper mantle.

关键词： clinopyroxene hydrogen diffusion dehydration.