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中国麻风杂志 1999年第1期15卷 27-31页

作者：蒋娟张国成韦晓宇 TLmI J.m.Watson 中国医学科学院中国协和医科大学皮肤病研究所英国国际麻风救济会

麻风的周围神经损害可引起畸残。畸残预防(POD)是麻风防治不可分割的一部分,最重要的是对神经损害要早期发现、适当治疗。类固醇激素治疗麻风反应和神经功能损害(NFI)效果较好。国内也用标准剂量的类固醇激素治疗近期的 NFI。

关键词：麻风周围神经损害治疗

土星磁层顶的Kelvin-Helmholtz不稳定性和磁流体表面波

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空间科学学报 1984年第2期 105-111页

作者：濮祖荫,m.G.Kivelson 北京大学地球物理系洛杉矶加州大学地球和空间科学系

本文采用可压缩磁流体力学近似并选取Voyager-1的观测数据,讨论了土星磁层顶的Kelvin-Helmholtz不稳定性和磁流体表面波.计算表明,土星磁层随星体自转同磁鞘流之间的速度差,可以在地方时午前、中午和距中午不远的午后磁层顶激发不稳定性... 详细信息

本文采用可压缩磁流体力学近似并选取Voyager-1的观测数据,讨论了土星磁层顶的Kelvin-Helmholtz不稳定性和磁流体表面波.计算表明,土星磁层随星体自转同磁鞘流之间的速度差,可以在地方时午前、中午和距中午不远的午后磁层顶激发不稳定性;午前和午后区有很强的非对称性.计算所得的波的特性与观测一致.

关键词：土星磁层磁鞘磁层 Kelvin-Helmholtz 磁流体力学不稳定性表面波波浪

Bounds on the Number of Light Neutrinos Species, g'1Coupling and Z - Z′mixing Angle in a U(1)B-Lmodel

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Journal of modern Physics 2015年第8期6卷 1077-1084页

作者： A. González-Sánchez A. Gutiérrez-Rodríguez m. A. Hernández-Ruíz Facultad de Fsica Universidad Autónoma de Zacatecas Zacatecas México LERmA CNRS UMR 8112 Observatoire de Paris Paris France Facultad de Ciencias Qumicas Universidad Autónoma de Zacatecas Zacatecas México

The constraints on the number of neutrinos generations, g'1 coupling and Z?- Z′ mixing angle through the invisible width method, and in the framework of a U(1)B-L model are obtained. Based on the experimental value reported by the lep for the rate , we obtained a bound on the g'1 coupling, . In addition, we derive 90% C.L. bounds on the Z?- Z′ mixing angle , improving the existing bounds by one order of magnitude.

关键词： Ordinary Neutrinos Neutral Currents models beyond the Standard model

偏头痛发作时激光诱发电位的地形学和双极分析

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世界核心医学期刊文摘（神经病学分册） 2005年第4期1卷 23-24页

作者： De Tommaso m Guido m. Libro G. 王英鹏 Dept. Neurologic and Psychiat. Sci. University of Bari Bari Italy Dr.

Objective. - The aim of this study was to perform further evaluation of laser- evoked potentials (leps) during miraine attacks using multichannel recording and topographic analysis. Specifically, this study aimed to confirm the pattern previously observed in acute migraine, while also defining the components of leps that are mainly modified during headache, as well as the correlation between features of leps and clinical variables. In addition, we aimed to conduct a dipolar source analysis of the main lep waves in migraine patients to check the variability in the source location of leps during acute migraine. Background. - An amplitude enhancement of leps was previously detected during migraine attack using a single scalp derivation on the vertex; hyperalgesia to heat stimuli was also detected for both the face and hand. methods. - Eighteen patients suffering from migraine without aura were analyzed. The supraorbital zones and the dorsum of the hand were stimulated on both the symptomatic and nonsymptomatic sides in all patients. The leps were recorded via 25 scalp electrodes. Dipolar source analysis of the P2 components was performed using a spherical model in all patients and using a realistic magnetic Resonance model in four patients. Results. - During attacks, the later waves, and particularly the P2 component, were significantly enhanced; the amplitude of the P2 component obtained during the attack by stimulation of the supraorbital zone on the side of the headache was significantly correlated with the intensity of pain and the frequency of headache. In our patients, the P2 wave was generated in the anterior cingulate cortex, with a shift toward its rostrocaudal portion, and was mainly devoted to elaboration of the emotive compound of pain during migraine attack. Conclusions. - Cortical activation by laser stimuli during migraine attack was confirmed. This effect was more pronounced in patients with a higher frequency of migraine attacks. This may be due to a l

关键词：头痛发作诱发电位致偏痛觉过敏头皮电极无症状诱导法热刺激皮层区尾状核

Thin-Plate Spline Analysis of Diversity in Field Populations of Codling moth, Cydia pomonella L. （lep., Tortricidae） in North West of Iran

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Journal of Agricultural Science and Technology 2011年第1期5卷 35-41页

作者： S. Khaghaninia S. A. mohammadi A. m. Sarafrazi K. Haddad Irani Nejad R. Zahiri Department of Plant Protection Faculty of Agriculture University of Tabriz Tabriz 51664 Iran Department of Agronomy ＆ Plant Breeding Faculty of Agriculture University of Tabriz Tabriz 51664 lran Institute of Plant Pests ＆ Diseases Research Tehran 19395 Iran Department of Biology University of Turku Turku 20014 Finland

In order to study morphological diversity of codling moth, Cydia pomonella （L.） using thin-plate spline analysis, nine geographical populations from four north western provinces of Iran namely East Azarbayjan, West Azarbayjan, Ardebil and Zandjan were collected during 2003 and 2004. 575 and 564 images were prepared from fore and hind wings, respectively. Then 15 and 11 landmarks were determined from fore and hind wings, respectively. With transforming of landmark＇s two dimensional coordinate data into partial warp scores, 26 and 18 scores were generated for fore and hind wings, respectively. Cluster analysis based on wing shape variables using Ward＇s algorithm assigned nine geographical populations into two groups. The pattern of grouping based on fore and hind wings was different in both sexes. Principal component analysis revealed discrimination between geographic populations and confirmed the result of cluster analysis. Among environmental parameters, wind speed showed the highest correlation with wing shape variables. Non significant correlation was observed between geographic and morphological distance matrices as revealed by mantel test.

关键词： Geometric morphometrics population variation thin-plate spline analysis codling moth Cydia pomonella (L.)

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基因组学方法研究猪脂肪沉积的遗传机理

国外畜牧学（猪与禽） 2013年第3期33卷 29-31页

作者：许栋王玲玉 m.Switonski 湖南农业大学动物科学技术学院

猪脂肪性状因能影响肉质和育肥效率而占有重要的地位,与此同时,猪被视为研究人类肥胖症和代谢症候群等诸多疾病的模型动物。当前人类,由于脂肪过度沉积而蔓延全球的肥胖症已演变为一个十分严峻的问题,因此,比较基因组学的运用将会为遗... 详细信息

猪脂肪性状因能影响肉质和育肥效率而占有重要的地位,与此同时,猪被视为研究人类肥胖症和代谢症候群等诸多疾病的模型动物。当前人类,由于脂肪过度沉积而蔓延全球的肥胖症已演变为一个十分严峻的问题,因此,比较基因组学的运用将会为遗传上研究脂肪和肥胖带来新的视点。脂肪性状是由多个微效基因控制的数量性状,这些遗传因子的相关系数在0.5左右。对猪全基因组扫描显示有500多个数量性状基因座(Quantitative Trait Locus,QTL)跟脂肪形成有关;进一步研究表明:与之相关的多个候选基因多态性已分析出来,包括基因编码的lep及其受体lepR、IGF2、FABP3、FABP4、mC4R及FTO。在这些因子中,对猪脂肪形成起到关键作用的是IGF2;与人类肥胖症最为密切的是FTO,然而,该基因对猪脂肪形成作用并不是十分明显。随着功能基因组学的发展,逐步揭示出更多跟脂肪沉积和油脂代谢相关的基因。近年来,以RNA干扰为主的表观基因组学被认为是获得与脂肪沉积相关基因的重要途径。总之,就现有研究成果来看,脂肪性状多态性的遗传背景是高度相关的。

关键词：猪基因组学脂肪沉积 QTL 候选基因

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1804例麻风复杂性足底溃疡的综合治疗

中国麻风杂志 1999年第1期15卷 24-26页

作者：严良斌张国成李文忠 J.m Watson 蒋娟韦晓宇中国医学科学院中国协和医科大学皮肤病研究所英国国际麻风救济会

在12个试点地区使用外科手术、石膏管型、支具、更换敷料、休息、防护鞋及改良的鞋垫等综合方法,对1804例麻风患者的2599个复杂性足底溃疡进行了治疗。结果1055例患者的1446个溃疡完全愈合(55%),院内的占70%。治愈者中有172人219个溃疡... 详细信息

在12个试点地区使用外科手术、石膏管型、支具、更换敷料、休息、防护鞋及改良的鞋垫等综合方法,对1804例麻风患者的2599个复杂性足底溃疡进行了治疗。结果1055例患者的1446个溃疡完全愈合(55%),院内的占70%。治愈者中有172人219个溃疡复发(16%),院外的复发数超过18%。综台治疗复杂性足底溃疡愈合率高,复发率低。减轻劳动强度、避免过度行走、加强足的自我保护知识教育、提供劳动救济、经济支持是预防溃疡复发的主要措施。

关键词：麻风复杂性足底溃疡愈合综合治疗治疗

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心脏X综合征患者的异常皮质疼痛过程

世界核心医学期刊文摘（心脏病学分册） 2005年第10期1卷 43-44页

作者： Valeriani m. Sestito A. Le Pera D. G. A. Lanza 滕增辉 Istituto di Cardiologia Universit Cattolica del Sacro Cuore Largo A. Gemelli 8 00168 Roma Italy

Previous studies suggested that an enhanced pain sensitivity is present in patients with cardiac syndrome X(SX). We investigated whether SX patients present abnormalities in the electrical cerebral signals generated by pain stimuli. methods and results: Cortical laser evoked potentials(leps) were recorded in 16 SX patients, in 10 patients with refractory angina due to obstructive coronary artery disease(CAD) and in 13 healthy controls. leps were recorded during stimulation of chest and right hand dorsum. Three sequences of painful stimuli were applied at each site. Subjective pain rating was assessed by a 0- 100 mm visual analogic scale(VAS). Basal leps did not differ among groups and there were no differences for most lep components across the repetitions of stimuli. However, the amplitude of the N2/P2 lep component, specifically reflecting cortical pain processing, decreased across the three sequences of stimuli in controls and CAD patients, but not in SX patients. Compared with the first sequence, the N2/P2 amplitude during the third sequence of stimuli in the three groups was 77± 16, 56± 24, and 99± 34% , respectively, for chest(P=0.001), and 63± 31, 72± 17, and 98± 46% , respectively, for right hand(P=0.03) stimulation. The changes in VAS pain score across the three sequences paralleled those of N2/P2 amplitude. Conclusion: Our data show that in SX patients, central handling of painful stimuli is characterized by inadequate habituation, which might play a role in determining the peculiar clinical characteristics of anginal chest pain of these patients.

关键词：右手背脑电信号视觉模拟诱发电位特异性

Antibacterial activity of leptogium cochleatum and leptogium moluccanum

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Studies in Fungi 2022年第1期7卷 139-142页

作者： Andrea Pauline B.manlapaz mitzi I.mariano Odessa Rona m.Reyes Laureena C.Rodriguez Jaycee Augusto G.Paguirigan Department of Biological Sciences College of ScienceUniversity of Santo TomasManila 1008Philippines Korean Lichen Research Institute Sunchon National University255 Jungang-roSuncheon-siJeollanam-do 57922South Korea

Currently there is an increase in the emergence and re-emergence of bacterial infections,and lichens are potential sources of pharmaceutically important secondary metabolites to halt this *** are unique plant-like organisms which are relatively less explored in the ***,lichen extracts of leptogium cochleatum and leptogium moluccanum were tested against Escherichia coli,Enterobacter agglomerans,Klebsiella pneumoniae,Pseudomonas aeruginosa,and Staphylococcus aureus using paper disk diffusion *** extract of *** led to a 17.14 mm zone of inhibition(ZOI)against ***,while hexane extract of *** led to a 15.28 mm ZOI against *** extracts of *** exhibited a ZOI of 15.86 mm against *** and 14.84 mm ZOI against *** bioactivities exhibited by the lichen extracts may be due to the secondary metabolites detected using thin layer ***,lichen-derived bioactive compounds hold great promise for pharmaceutical applications for the benefit of human life.

关键词： lep tum benefit