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Nanofibrous ε-polycaprolactone scaffolds containing Ag-doped magnetite nanoparticles: Physicochemical characterization and biological testing for wound dressing applications in vitro and in vivo

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Bioactive materials 2021年第7期6卷 2070-2088页

作者： m.K.Ahmed m.a.zayed S.I.El-dek mayssa Abdel Hady Doaa H.El Sherbiny Vuk Uskokovic Faculty of Nanotechnology for Postgraduate studies Cairo UniversityEl-Sheikh Zayed 12588Egypt Department of Physics Faculty of ScienceSuez UniversitySuez 43518Egypt Chemistry Department Faculty of ScienceCairo University12613GizaEgypt materials Science and Nanotechnology Department Faculty of Postgraduate Studies for Advanced SciencesBeni-Suef UniversityBeni SuefEgypt Pharmaceutical Technology Department National Research CentreDokiiGizaEgypt Advanced materials and Nanobiotechnology Laboratory TardigradeNano LLCIrvineCA92604USA Department of Biochemistry Faculty of DentistryModern University for Technology and InformationMokattamCairoEgypt

Skin wounds can lead to numerous complications with dangerous health *** this work,magnetite nanoparticles were doped with different concentrations of antimicrobial silver(Ag)ions and incorporated into the electrospun nanofibrous ε-polycaprolactone(PCL)*** and scaffolds with various Ag contents were characterized using a range of physicochemical *** entered magnetite as cations and preferentially positioned at tetrahedral sites,introducing lattice distortions and topographic *** of the structure due to accommodation of Ag expanded the lattice in the bulk and contracted it on the surface,where broadened distribution of Fe-O coordinations was *** spin canting and diminishing the double exchange interaction through altered distribution of ferric and ferrous ions,Ag softened the magnetism of *** making the nanoparticle structure more defective,Ag modified the interface with the polymer and promoted the protrusion of the nanoparticles from the surface of the polymeric nanofibers,thus increasing their roughness and hydrophilicity,with positive repercussions on cell adhesion and *** the viability of human melanocytes and the antibacterial activity against *** and *** increased with the concentration of Ag in the magnetite phase of the *** wound healing rate in rats also increased in direct proportion with the concentration of Ag in the magnetite phase,and no abnormalities in the dermal and epidermal tissues were visible on day 10 in the treatment *** results imply an excellent potential of these composite nanofibrous scaffolds for use as wound dressings and in other reconstructive skin therapies.

关键词： Tissue engineering Wound healing Skin magnetic nanoparticles Nanofiber

Novel Spectrophotometric method for Determination of macro-paracetamol via Reaction with Bromine

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分析测试学报 1999年第1期 32-35页

作者： F.A.Nour el Dien, m.a.zayed, G.G.mohamed(Chemistry Department, Faculty of Science, Cairo University, Giza A.R.Egypt )

ｎｔｒｏｄｕｃｔｉｏｎｐ＿ＡＡＰｉｓｏｎｅｏｆｔｈｅｍｏｓｔｉｍｐｏｒｔａｎｔ，ｓａｆｅ，ａｎｄｅｆｅｃｔｉｖｅｎｏｎ＿ｓａｌｉｃｙｌａｎａｌｇｅｓｉｃａｎｄａｎｔｉｐｙｒｅｔｉｃａｇｅｎｔｓ．Ｉｔｉｓｔｈｅｂｉｏｄ... 详细信息

ｎｔｒｏｄｕｃｔｉｏｎｐ＿ＡＡＰｉｓｏｎｅｏｆｔｈｅｍｏｓｔｉｍｐｏｒｔａｎｔ，ｓａｆｅ，ａｎｄｅｆｅｃｔｉｖｅｎｏｎ＿ｓａｌｉｃｙｌａｎａｌｇｅｓｉｃａｎｄａｎｔｉｐｙｒｅｔｉｃａｇｅｎｔｓ．Ｉｔｉｓｔｈｅｂｉｏｄｅｇｒａｄａｔｉｏｎｐｒｏｄｕｃｔ...

关键词： p_AAP Determination Bromine Spectrophotometric method

糖尿病足的区域骨骼肌灌注分布可鉴别短期愈合与未愈合的溃疡

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国际医学放射学杂志 2023年第4期 489-489页

作者： J.Zheng R.Li E.E.Dickey Y.Yan m.a.zayed J.A.Zellers 谢俊诗

摘要目的利用mRI技术描述糖尿病病人（伴或不伴有足部溃疡）的足部灌注分布，并确定区域灌注测量识别溃疡愈合状态的能力。方法招募3组参与者（15名/组）：对照

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The 3D Inverse Problem of the Wave Equation for a General multi-connected Vibrating membrane with a Finite Number of Piecewise Smooth Boundary Conditions

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Acta mathematica Sinica,English Series 2005年第4期21卷 733-752页

作者： E.m.E.zayed mathematics Department Faculty of ScienceZagazig UniversityZagazig.Egypt

The trace of the wave kernel μ（t） =∑ω=1^∞ exp（-itEω^1/2）, where {Eω}ω^∞=1 are the eigenvalues of the negative Laplacian -△↓2 = -∑k^3=1 （δ/δxk）^2 in the （x^1, x^2, x^3）-space, is studied for a variety of bounded domains, where -∞ 〈 t 〈 ∞ and i= √-1. The dependence of μ （t） on the connectivity of bounded domains and the Dirichlet, Neumann and Robin boundary conditions are analyzed. Particular attention is given for a multi-connected vibrating membrane Ω in Ra surrounded by simply connected bounded domains Ω j with smooth bounding surfaces S j （j = 1,……, n）, where a finite number of piecewise smooth Dirichlet, Neumann and Robin boundary conditions on the piecewise smooth components Si^＊（i = 1 ＋ kj-1,……, kj） of the bounding surfaces S j are considered, such that S j = Ui-1＋kj-1^kj Si^＊, where k0=0. The basic problem is to extract information on the geometry Ω by using the wave equation approach from a complete knowledge of its eigenvalues. Some geometrical quantities of Ω （e.g. the volume, the surface area, the mean curvuture and the Gaussian curvature） are determined from the asymptotic expansion ofexpansion of μ（t） for small │t│.

关键词： Inverse problem Wave kernal Eigenvalues Greens function multi-connected vibrating membrane Negative Laplacian Heat kernel

Asymptotic Expansions of the Heat Kernel of the Laplacian for General Annular Bounded Domains with Robin Boundary Conditions：Further Results

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Acta mathematica Sinica,English Series 2003年第4期19卷 679-694页

作者： E.m.E.zayed Departmentofmathematics FacultyofScienceZagazigUniversityZagazigEgypt

The asymptotic expansions of the trace of the heat kernel Θ(t) = Σ_(v =1)~∞exp(-tλ_v) for small positive t, where {λ_v} are the eigenvalues of the negative Laplacian-△_n = -Σ_(i = 1)~n(partial deriv/(partial deriv)x^i)~2 in R^n (n = 2 or 3), are studied for ageneral annular bounded domain Ω with a smooth inner boundary (partial deriv)Ω_1 and a smoothouter boundary (partial deriv)Ω_2, where a finite number of piecewise smooth Robin boundaryconditions (partial deriv/(partial deriv)n_j + γ_j)φ = 0 on the components Γ_j(j = 1, …, k) of(partial deriv)Ω_1 and on the components Γ_j(j = k + 1, …, m) of (partial deriv)Ω_2 areconsidered such that (partial deriv)Ω_1 = ∪_(j = 1)~kΓ_j and (partial deriv)Ω_2 = ∪_(j = k +1)~mΓ_j and where the coefficients γ_j(j = 1, …, m) are piecewise smooth positive functions. Someapplications of Θ(t) for an ideal gas enclosed in the general annular bounded domain Ω are *** results are also obtained.

关键词： inverse problem heat kernel eigenvalues Robin boundary conditions classical ideal gas

INVERSE PROBLEmS FOR A GENERAL mULTI-CONNECTED BOUNDED DRUm WITH APPLICATIONS IN PHYSICS

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Acta mathematica Scientia 2003年第1期23卷 104-116页

作者： E.m.E.zayed mathematics Department Faculty of Science Zagazig University Zagazig Egypt

This paper studies the influence of a finite container on an ideal *** trace of the heat kernel (t) =exp, where are the eigenvalues of the negative Laplacian -in Rn(n = 2 or 3), is studied for a general multi-connected bounded drum ft which is surrounded by simply connected bounded domains Ωi with smooth boundaries Ωi(i = 1,… ,m) where the Dirichlet, Neumann and Robin boundary conditions on Ωi(i = 1,…,m) are considered. Some geometrical properties of Ω are determined. The thermodynamic quantities for an ideal gas enclosed in Ω are examined by using the asymptotic expansions of (t) for short-time t. It is shown that the ideal gas can not feel the shape of its container Ω, although it can feel some geometrical properties of it.

关键词： Inverse problem heat kernel eigenvalues an ideal gas multi-connected bounded domain

The Asymptotics of the Two-Dimensional Wave Equation for a General multi-Connected Vibrating membrane with Piecewise Smooth Robin Boundary Conditions

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Acta mathematica Sinica,English Series 2004年第2期20卷 209-222页

作者： E.m.E.zayed Department of mathematics Faculty of ScienceZagazig UniversityZagazigEgypt

The asymptotic expansion for small |t| of the trace of the wave kernel , where and are the eigenvalues of the negative Laplacian in the (x 2,x 2)-plane, is studied for a multi-connected vibrating membrane ? in R 2 surrounded by simply connected bounded domains ? j with smooth boundaries ?? j (j = 1, ..., n), where a finite number of piecewise smooth Robin boundary conditions on the piecewise smooth components Γ i (i = 1+k j?1, ..., k j ) of the boundaries ?? j are considered, such that and k 0 = 0. The basic problem is to extract information on the geometry of ? using the wave equation approach. Some geometric quantities of ? (e. g. the area of ?, the total lengths of its boundary, the curvature of its boundary, the number of the holes of ?, etc.) are determined from the asymptotic expansion of the trace of the wave kernel for small |t|.

关键词： Inverse problem Wave kernel Eigenvalues Robin boundary conditions Vibrating membrane Hearing the shape of a drum

DNA Dynamics Studied Using the Homogeneous Balance method

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Chinese Physics Letters 2012年第8期29卷 9-11页

作者： E.m.E.zayed A.H.Arnous mathematics Department Faculty of ScienceZagazig UniversityP.O.Box 44519ZagazigEgypt

We employ the homogeneous balance method to construct the traveling waves of the nonlinear vibrational dynamics modeling of *** new explicit forms of traveling waves are *** is shown that this method provides us with a powerful mathematical tool for solving nonlinear evolution equations in mathematical *** and weaknesses of the proposed method are discussed.

关键词： traveling nonlinear method

The Asymptotics of the Heat Semigroup for a General Bounded Domain with mixed Boundary Conditions

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Acta mathematica Sinica,English Series 2000年第4期16卷 627-636页

作者： E. m. E. zayed mathematics Department. Faculty of Science. Zagazig University. Zagazig. Egypt

Small-time asymptotics of the trace of the heat semigroup θ（t）=Σv=1x exp（-tμv）. where {μv} are the eigenvalues of the uegative Laplacian -Δ= -Σβ=12（/xβ）2 in the （x1, x2）-plane. is studied for a general bounded domain Ω with a smooth boundary Ω. where a finite number of Dirichlet. Neumann and Robin boundary conditions, on the piecewise smooth parts Γi（i=1, ..., n） of )Ω such that)Ω=∪i=1nΓ are considered. Some geometrical properties associated with Ω are determined

关键词： Heat semigroup Inverse problem mixed boundary conditions Eigenvalues