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Challenges and improvement strategies in the hospitalization of chronic multimorbid patients

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World Journal of Clinical Cases 2025年第3期13卷 35-41页

作者： Andres Fontalba-Navas Francisco Pozo muñoz Rogelio garcia Cisneros maria Jose garcia Larrosa maria del mar Callejon Gil Ignacio garcia Delgado maria Belen Jimenez martinez Antequera Hospital Northern Málaga Integrated Healthcare AreaAntequera 29200AndalusiaSpain Department of Public Health and Psychiatry University of MálagaMálaga 29010Spain Antequera Hospital Northern Málaga Antequera Integrated Healthcare AreaAntequera 29200MálagaSpain

BACKGROUND Addressing the growing challenge of hospitalizing chronic multimorbid patients,this study examines the strain these conditions impose on healthcare systems at a local level,focusing on a pilot *** diseases and complex patients require comprehensive management strategies to reduce healthcare burdens and improve patient *** proven effective,this pilot model has the potential to be replicated in other healthcare settings to enhance the management of chronic multimorbid *** To evaluate the effectiveness of the high complexity unit(HCU)in managing chronic multimorbid patients through a multidisciplinary care model and to compare it with standard hospital *** The study employed a descriptive longitudinal approach,analyzing data from the Basic minimum Data Set(BmDS)to compare hospitalization variables among the HCU,the Internal medicine Service,and other services at Antequera Hospital throughout *** HCU,designed for patients with complex chronic conditions,integrates a patient-centered model emphasizing multidisciplinary care and continuity *** The study employed a descriptive longitudinal approach,analyzing data from the BmDS to compare hospitalization variables among the HCU,the Internal medicine Service,and other services at Antequera Hospital throughout *** HCU,designed for patients with complex chronic conditions,integrates a patient-centered model emphasizing multidisciplinary care and continuity *** This study demonstrates the effectiveness of the HCU in managing patients with complex chronic diseases through a multidisciplinary *** coordinated care provided by the HCU results in improved patient outcomes,reduced unnecessary hospitalizations,and better management of patient *** superiority of the HCU compared to standard care is evident in key outcomes such as fewer readmissions and higher patient satisfaction,reinforcing its value as a model of ca

关键词： High complexity unit Chronic multimorbidity Patient-centered care Integrated care Healthcare management

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用于高温无损检测的超声换能器

声学技术 1992年第4期11卷 39-40页

作者： m.a.garcia-Olias 高玉

A new strategy for corrosion protection of porous stainless steel using polypyrrole films

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Journal of materials Science & Technology 2020年第2期37卷 85-95页

作者： C.garcia-Cabezon C.garcia-Hernandez m.L.Rodriguez-mendez F.martin-Pedrosa materials Engineering E.I.I.Universidad de Valladolid47011 ValladolidSpain UVASENS E.I.I.Universidad de Valladolid47011 ValladolidSpain

In this work,a method to improve the protection against corrosion of porous sintered stainless steel is *** is based on the electrodeposition of polypyrrole(PPy)layers doped with a large size counterion such as dodecylbenzenesulphonic acid(DBSA),a conducting polymer with high corrosion resistance and good *** efficacy of PPy coating depends on the adequate adhesion between the metal substrate and the coating *** protection against corrosion has been tested using 316 L stainless steel(SS)powder sintered at different conditions to evaluate the effect of the sintering atmosphere(nitrogen and vacuum)and cooling rates(furnace and water)on corrosion resistance,while wrought 316 L SS has been used as reference *** addition,two electrochemical deposition techniques have been tested to select the most *** circuit potential evolution,anodic polarization measurements and electrochemical impedance spectra have been used to evaluate corrosion protection in phosphate buffer saline *** has been evidenced that a more homogeneous and stable coating was obtained in the case of porous stainless *** corrosion potential shifted to nobler values and the anodic polarization branch became more *** porous samples have a good passivation performance with a lower stable passive current density and a higher breakdown *** transfer electronic resistance and the impedance module increase more than one order of ***,the porosity of sintered stainless steel is seen as an advantage for the improvement of the adherence of the PPy *** best corrosion protection is found for samples sintered in nitrogen and water-cooled.

关键词： Stainless steel Powder metallurgy Protection corrosion Electrodeposited films Polymer coatings

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内源植物生长素与克力迈丁红桔生育的关系

浙江柑橘 1986年第2期 47-48页

作者： m.a.garcia—papi ,徐崇敬

一般认为,座果与果实发育是受内源植物生长素控制的。'monreal'克力迈丁（有籽）和'Fino'克力迈丁（单性结实）显示出极不相同的生产习性。在中胚轴生物测定肘具活性的物质,用带有异丙醇:NH3:水的纸层析,在柑桔的甲醇提取物酸性馏分... 详细信息

一般认为,座果与果实发育是受内源植物生长素控制的。'monreal'克力迈丁（有籽）和'Fino'克力迈丁（单性结实）显示出极不相同的生产习性。在中胚轴生物测定肘具活性的物质,用带有异丙醇:NH3:水的纸层析,在柑桔的甲醇提取物酸性馏分测得两种活性组分(组

关键词：植物生长素座果中胚轴生物测定提取物甲醇馏分酸性一元醇化工单元操作赤霉素脱落酸红桔观果树木内源

On SIR epidemic models with generally distributed infectious periods： Number of secondary cases and probability of infection

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International Journal of Biomathematics 2017年第2期10卷 157-169页

作者： A. Gomez-Corral m. Lopez-garcia Instituto de Ciencias matemdticas CSIC- UAM- UC3M- UCM Calle Nicolds Cabrera 13-15 Madrid 28049 Spain Department of Applied mathematics School of Mathematics University of Leeds Leeds LS29JT UK

Recently, Clancy [SIR epidemic models with general infectious period distribution, Statist. Prob. Left. 85 （2014） 1-5] has shown how SIR epidemics in which individuals＇ infection periods are not necessarily exponentially distributed may be modeled in terms of a piecewise-deterministic markov process （PDmP）. In this paper, we present a more detailed description of the underlying PDmP, from which we analyze the population transmission number and the infection probability of a certain susceptible individual.

关键词： Number of secondary cases piecewise-deterministic markov process proba-bility of infection SIR epidemic model.

A Single JAZ Repressor Controls the Jasmonate Pathway in marchantia polymorpha

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molecular Plant 2019年第2期12卷 185-198页

作者： Isabel monte Jose m. Franco-Zorrilla Gloria garcia-Casado Angel m. Zamarreno Jose m. garcia-mina Ryuichi Nishihama Takayuki Kohchi Roberto Solano Department of Plant molecular Genetics Centro Nacional de Biotecnologia Consejo Superior de Investigaciones Cientificas (CNB-CSIC) 28049 Madrid Spain Genomics Unit Centro Nacional de Biotecnologia Consejo Superior de Investigaciones Cientificas (CNB-CSIC) 28049 Madrid Spain Environmental Biology Department University of Navarra Navarre Spain Graduate School of Biostudies Kyoto University Kyoto 606-8502 Japan

JAZ proteins are negative regulators of jasm onate responses,acting both as repressors of transcription factors and as co-receptors of JA-lle. The high redundancy of JAZ genes in angiosperms has hindered the characterization of a complete depletion of JAZ function. moreover, the recent discovery that dn- OPDA is the jasmonate ligand in marchantia polymorpha demonstrates that JA-lle is not the sole COI1/ JAZ ligand in land plants and highlights the importance of studying JAZ co-receptors in bryophytes? Here, we have exploited the low gene redundancy of the liverwort m. polymorpha to characterize the single mpJ4Z in this early diverging plant lineage. We clarify the phylogenetic history of the TIFY family, demonstrate that mpJAZ is the ortholog of AtJAZ with a conserved function, and characterize its repressor activity of dn-OPDA resp on ses. Our results show that, con sistent with previous findings in Arabidopsis, mpJAZ represses jasmonates biosynthesis, senescence, and plant defenses, and promotes cell growth and reproductive fitness, highlighting the power of studies in marchantia.

关键词： Jasmonate repressors marchantia Hormone signaling evolution gene redundancy

Bioleaching of zinc from gold ores using Acidithiobacillus ferrooxidans

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International Journal of minerals,metallurgy and materials 2009年第4期16卷 368-374页

作者： Pakawadee Kaewkannetra Francisco Jose garcia-garcia Tze Yen Chiu Department of Biotechnology Faculty of TechnologyKhon Kaen University Corrosion and Protection Centre School of MaterialsThe University of Manchester Centre of Water Science Cranfield University

The present work investigated microbial leaching of zinc from ore using Acidithiobacillus ferrooxidans （ATCC 14859）. The ore samples, consisted of 13wt% zinc, were obtained from a gold mine in north-eastern Thailand. A shake flask study was performed on the ore samples using a rotary shaker under the following fixed conditions （250 r·min^-1, 30℃ for 16 d）. The influence of various conditions, namely medium type （with and without iron）, particle ore size （〈20, 20-40, 40-60, 60-100, and 〉100 mesh）, ore density （20 kg·m^-3, 50 kg·m^-3, and 100 kg·m^-3）, and pH of the medium （2, 2.5, 2.8, and 3）, were investigated. The microbial leaching was assessed by determining the concentration of zinc in the medium and compared with the initial sample concentration. The results show that Acidithiobacillus ferrooxidans can successfully leach zinc by as much as 6 times compared with the control experiment （without Acidithiobacillus ferrooxidans ferrooxidans）. The maximum efficiency （92.3%） for microbial leaching is obtained in iron-containing medium, 20-40 mesh ore sizes, 20 kg·m^-3 ore density at pH 2.8, and the zinc content is found in the medium at about 120 mg·m^-1.

关键词： bioleaching Acidithiobacillusferrooxidans gold ores gold mine

A pathophysiology-based approach to the management ot early priapism

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Asian Journal of Andrology 2013年第1期15卷 20-26页

作者： Jason R Kovac Siu K mak maurice m garcia Tom FLue Scott Department of Urology Baylor College of Medicine Houston TX 77030 USA The Chinese University of Hong Kong Department of Surgery Prince of Wales HosPital Hong Kong China Department of Urology University of California San Francisco CA 94143 USA

Priapism is a rare condition that involves persistent penile erection for greater than 4 h. Distinct variants exist, each with unique characteristics. Ischemic priapism is a painful medical emergency that may occur as a result of veno-occlusion leading to hypoxia and tissue death. Recurrent bouts of ischemic priapism, or stuttering priapism, require treatment for individual attacks as well as long-term prevention. Non-ischemic priapism is associated with trauma and may be managed conservatively. Recent advances into the pathophysiology of priapism have allowed the development of treatment algorithms that specifically target the mechanisms involved. In this review, we outline the basics of smooth muscle contraction and describe how derangement of these pathways results in priapism. A pathophysiological approach to the treatment of priapism is proposed with duration-based algorithms presented to assist in management.

关键词： algorithm ischemic management priapism T-shunt tunneling

Geodesic Vulnerability Approach for Identification of Critical Buses in Power Systems

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Journal of modern Power Systems and Clean Energy 2021年第1期9卷 37-45页

作者： Jesus Beyza Eduardo garcia-Paricio Hector F.Ruiz Jose m.Yusta Instituto Tecnologico de morelia Avenida Tecnologico 1500Lomas de Santiaguito58120Mexico the Department of Electrical Engineering University of ZaragozaC/Maria de Luna 350018Spain

One of the most critical issues in the evaluation of power systems is the identification of critical buses. For this purpose, this paper proposes a new methodology that evaluates the substitution of the power flow technique by the geodesic vulnerability index to identify critical nodes in power *** methods are applied comparatively to demonstrate the scope of the proposed approach. The applicability of the methodology is illustrated using the IEEE 118-bus test system as a case study. To identify the critical components, a node is initially disconnected, and the performance of the resulting topology is evaluated in the face of simulations for multiple cascading faults. Cascading events are simulated by randomly removing assets on a system that continually changes its structure with the elimination of each component. Thus, the classification of the critical nodes is determined by evaluating the resulting performance of 118 different topologies and calculating the damaged area for each of the disintegration curves of cascading failures. In summary, the feasibility and suitability of complex network theory are justified to identify critical nodes in power systems.

关键词： Power system critical node complex network theory cascading failure load flow