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Thermal stresses in infinite circular cylinder subjected to rotation

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Applied mathematics and mechanics(English Edition) 2012年第8期33卷 1059-1078页

作者： A.m.ABD-alla G.A.YAHYA Department of mathematics Faculty of ScienceTaif UniversitySaudi Arabia Department of Physics Faculty of ScienceTaif UniversitySaudi Arabia Department of Physics Faculty of ScienceAswan UniversityAswan 81528AswanEgypt

The present investigation is concerned with the effect of rotation on an infi- nite circular cylinder subjected to certain boundary conditions. An analytical procedure for evaluation of thermal stresses, displacements, and temperature in rotating cylinder subjected to thermal load along the radius is presented. The dynamic thermal stresses in an infinite elastic cylinder of radius a due to a constant temperature applied to a variable portion of the curved surface while the rest of surface is maintained at zero temperature are discussed. Such situation can arise due to melting of insulating material deposited on the surface cylinder. A solution and numerical results are obtained for the stress components, displacement components, and temperature. The results obtained from the present semi-analytical method are in good agreement with those obtained by using the previously developed methods.

关键词： wave propagation thermoelasticity isotropic material rotating cylinder Lam’e potential thermal stress

Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

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Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

Effects of rotation and gravity on an electro-magneto-thermoelastic medium with diffusion and voids by using the Lord-Shulman and dual-phase-lag models

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Applied mathematics and mechanics(English Edition) 2019年第8期40卷 1135-1154页

作者： S.m.ABO-DAHAB A.m.ABD-alla A.A.KILANY Department of mathematics Faculty of SciencesTaif UniversityTaif 888Saudi Arabia Department of mathematics Faculty of ScienceSouth Valley UniversityQena 83523Egypt Department of mathematics Faculty of ScienceSohag UniversitySohag 82524Egypt

The effects of rotation and gravity on an electro-magneto-thermoelastic medium with diffusion and voids in a generalized thermoplastic half-space are studied by using the Lord-Shulman (L-S) model and the dual-phase-lag (DPL) model. The analytical solutions for the displacements, stresses, temperature, diffusion concentration, and volume fraction field with different values of the magnetic field, the rotation, the gravity, and the initial stress are obtained and portrayed graphically. The results indicate that the effects of gravity, rotation, voids, diffusion, initial stress, and electromagnetic field are very pronounced on the physical properties of the material.

关键词： electromagnetic field gravity field rotation initial stress voids diffusion normal mode analysis Lord-Shulman (L-S) model dual-phase-lag (DPL) model

Effect of rotation on the surface wave propagation in magneto-thermoelastic materials with voids

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Journal of Ocean Engineering and Science 2018年第4期3卷 334-342页

作者： A.m.Farhan A.m.Abd-alla Physics Department Faculty of ScienceJazan UniversitySaudi Arabia Physics Department Faculty of ScienceZagzig UniversityEgypt mathematics Department Faculty of ScienceSohag UniversityEgypt

The present investigation is focused on studying the surface wave propagation in a generalized magneto-thermoelastic materials taking(Green Lindsay)model with *** general surface wave speed is derived to study the effects of magnetic field and rotation on surface wave in the presence of *** addition the present study can be comprehensively applied to the magneto-thermoelastic medium with *** possible non-dimensional frequency of surface wave propagation has been obtained as the solution of an algebraic equation involving a determinant whose elements contain the material parameters,the direction of applied magnetic field and rotation of surface wave *** comparisons for the physical quantities are established numerically and represented graphically in different cases with respect to the used effects.

关键词： Green Lindsay theory Thermoelasticity Surface waves.

Effect of magnetic field on poroelastic bone model for internal remodeling

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Applied mathematics and mechanics(English Edition) 2013年第7期34卷 889-906页

作者： A.m.ABD-alla S.m.ABO-DAHAB Department of mathematics Faculty of Sciences Taif University Department of mathematics Faculty of Science Sohag University Department of mathematics Faculty of Science South Valley University

This paper studies the effects of the magnetic field and the porosity on a poroelastic bone model for internal remodeling. The solution of the internal bone remodeling process induced by a magnetic field is presented. The bone is treated as a poroelastic material by Biot＇s formulation. Based on the theory of small strain adaptive elasticity, a theoretical approach for the internal remodeling is proposed. The components of the stresses, the displacements, and the rate of internal remodeling are obtained in analytical forms, and the numerical results are represented graphically. The results indicate that the effects of the magnetic field and the porosity on the rate of internal remodeling in bone are very pronounced.

关键词： wave propagation poroelastic wet bone internal remodeling magnetic field

Plane Vibrations in a Transversely Isotropic Infinite Hollow Cylinder Under Effect of the Rotation and magnetic Field

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Computer modeling in Engineering & Sciences 2017年第2期113卷 151-170页

作者： F.S.Bayones A.m.Abd-alla math.Dept. Faculty of ScienceTaif UniversitySaudi Arabia mathematics Department Faculty of ScienceSohagEgypt

The aim of this paper is to study the effects of rotation and magnetic field on the plane vibrations in a transversely isotropic material of an infinite hollow *** natural frequency of the plane vibrations in the case of harmonic vibrations has been *** natural frequencies are calculated numerically and the effects of rotation and magnetic field are *** numerical results obtained have been illustrated graphically to understand the behavior of frequency equation with different values of frequencyωunder effects the rotation and magnetic *** was made with the results obtained in the presence and absence of the rotation and magnetic *** results indicate that the effect of rotation and magnetic field are very pronounced.

关键词： Plane transversely isotropic rotating magnetic field homogeneous transversely isotropic Natural frequencies

Influence of magnetic field on free vibrations in elastodynamic problem of orthotropic hollow sphere

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Applied mathematics and mechanics(English Edition) 2014年第8期35卷 1051-1066页

作者： S.R.mAHmOUD A.m.ABD-alla Department of mathematics Science FacultyKing Abdulaziz UniversityJeddah 21589Saudi Arabia Department of mathematics Science FacultySohag UniversitySohag 82524Egypt

The effect of magnetic field on the plane vibrations for an elastodynamic orthotropic sphere is studied. Equations of elastodynamic problems of the orthotropic hollow sphere in terms of displacement are solved. The numerical results of the frequency equations in the presence of magnetic field are discussed and shown graphically. Compar-isons are made with the result in the presence and absence of magnetic field in the case of orthotropic sphere. The results show that the effect of magnetic field is very pronounced.

关键词： magnetic field elastodynamic orthotropic free vibration hollow sphere

On thermoelastic problem based on four theories with the efficiency of the magnetic field and gravity

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Journal of Ocean Engineering and Science 2024年第4期9卷 338-347页

作者： A.A.Kilany A.N.Abd-alla A.m.Abd-alla S.m.Abo-Dahab Department of mathematics Faculty of ScienceSohag UniversitySohag 82524 Egypt Department of Computer Science Faculty of Computers and InformationLuxor UniversityEgypt Department of mathematics Faculty of ScienceSouth Valley UniversityQena 83523Egypt

The fundamental objective of this paper is to study the effectiveness of magnetic field and gravity on an isotropic homogeneous thermoelastic structure based on four theories of generalized *** another meaning,the models of coupled dynamic theory(CDT),Lord-Shulman(LS),Green-Lindsay(GL)as well as Green-Naghdi(GN II)will be taken in the ***,applying the harmonic method(normal mode technique),the solution of the governing equations and the expressions for the components of the displacement,temperature and(mechanical and maxwell’s)stresses is taken into account and calculated *** impacts of the gravity and magnetic field are illustrated graphically which are pronounced on the different physical ***,the results of some research that others have previously obtained may be found some or all of them as special cases from this study.

关键词： Generalized thermoelasticity Gravity magnetic field Green and Naghdi TheoryⅡ Normal mode approach

SBL-JP-0004:A promising dual inhibitor of JAK2 and PI3KCD against gastric cancer

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Oncology Research 2025年第1期33卷 235-243页

作者： HASSAN m.OTIFI Department of Pathology College of MedicineKing Khalid UniversityAbha62521Saudi Arabia

Background:Gastric cancer(GC)remains a global health burden and is often characterized by heterogeneous molecular profiles and resistance to conventional *** phosphoinositide 3-kinase and PI3K and Janus kinase(JAK)signal transducer and activator of transcription(JAK-STAT)pathways play pivotal roles in GC progression,making them attractive targets for therapeutic ***:This study applied a computational and molecular dynamics simulation approach to identify and characterize SBL-JP-0004 as a potential dual inhibitor of JAK2 and PI3KCD *** and SNU-5 GC cells were used for in vitro ***:SBL-JP-0004 exhibited a robust binding affinity for JAK2 and PI3KCD kinases,as evidenced by molecular docking scores and molecular dynamics *** interactions and Gibbs binding free energy estimates confirmed stable and favorable interactions with target ***-JP-0004 displayed an half-maximal inhibitory concentration(IC_(50))value of 118.9 nm against JAK2 kinase and 200.9 nm against PI3KCD ***-JP-0004 exhibited potent inhibition of cell proliferation in KATOIII and SNU-5 cells,with half-maximal growth inhibitory concentration(GI50)values of 250.8 and 516.3 nm,respectively.A significant elevation in the early phase apoptosis(28.53%in KATOIII cells and 26.85%in SNU-5 cells)and late phase apoptosis(17.37%in KATOIII cells and 10.05%in SNU-5 cells)were observed with SBL-JP-0004 treatment compared to 2.1%and 2.83%in their respective ***:The results highlight SBL-JP-0004 as a promising dual inhibitor targeting JAK2 and PI3KCD kinases for treating GC and warrant further preclinical and clinical investigations to validate its utility in clinical settings.

关键词： Gastric cancer(GC) Dual inhibition JAK2 PI3KCD SBL-JP-0004 molecular docking molecular dynamics simulation