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主动固定双极导线长期经静脉临时起搏治疗miller-Fisher综合征患者的重度自主神经功能障碍:病例报道

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世界核心医学期刊文摘(心脏病学分册) 2007年第9期 47-47页

作者： Kordouni m. Jibrini m. siddiqui m.A. 郭俊 Division of Cardiology Mount Sinai Hospital Chicago and Chicago Medical School North Chicago IL United States

对Guillain-Barre综合征(GBS)或其变异类型miller-Fisher综合征(mFS)患者的重度自主神经功能障碍的治疗包括植入永久起搏器。本文报道1例伴有重度心动过缓和心搏停止的mFS患者,最初接受体外永

关键词：自主神经功能障碍经静脉 miller-Fisher 综合征综合病症患者导线重度

应用X Stop棘突间植入物治疗腰椎管狭窄术后一年的疗效

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脊柱外科杂志 2007年第3期5卷 188-188页

作者： siddiqui m Smith FW Wardlaw D 王乃国（译）

本文报道了一项前瞻性观察研究的结果。在该前瞻性研究中，应用XStop植入物治疗有症状的腰椎管狭窄，并定期收集术后患者的临床疗效结果，进行前后比较分析。XStop棘突间撑开装置是一种比较新的棘突间植入物，用以治疗有症状的椎管狭窄... 详细信息

本文报道了一项前瞻性观察研究的结果。在该前瞻性研究中，应用XStop植入物治疗有症状的腰椎管狭窄，并定期收集术后患者的临床疗效结果，进行前后比较分析。XStop棘突间撑开装置是一种比较新的棘突间植入物，用以治疗有症状的椎管狭窄，尤其伴有神经源性间歇性跛行的患者。以前的一项随机研究显示，腰椎管狭窄患者行XStop植入后1年，其症状和躯体功能可以得到75％的改善。

关键词：腰椎管狭窄椎管狭窄术临床疗效植入物治疗棘突神经源性间歇性跛行术后患者

肥厚性幽门狭窄患儿是否需要进行泌尿道超声扫描检查

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世界核心医学期刊文摘（儿科学分册） 2005年第6期1卷 4-4页

作者： Cascio S. siddiqui m. m. F. Barrett A. m. 李开 Department of Paediatric Surgery Royal Victoria Infirmary Newcastle upon Tyne NE1 4LP United Kingdom

Aim: Few retrospective studies have evaluated infants with hypertrophic pyloric stenosis (HPS) for associated urological anomalies. They have led to contradictory conclusions. The aim of this study was to evaluate the incidence of urinary tract anomalies in infants with HPS and to establish the clinical significance of this association. methods: One hundred and twenty-two infants (100 boys) who underwent pyloromyotomy between 1992 and 2002 were prospectively evaluated. Screening ultrasound (Us) of the urinary tract was performed in 107 infants, while 15 did not attend their ultrasound appointment. Results: Renal ultrasound was abnormal in 4 (4%) of 107 screened patients with HPS. Three patients were found to have mild hydronephrosis and, in one patient, a small, normal kidney was detected. Two patients with hydronephrosis had Us follow-up and the third patient underwent Tc-99 mercaptoacetyl triglycine (mAG 3) scan. In all three patients, the hydronephrosis resolved completely on follow-up scan. Conclusion: The incidence of abnormal renal ultrasound in children with HPS is similar to the reported incidence of 3-6%determined with routine ultrasound screening of healthy newborns. The abnormalities detected were not clinically relevant and did not require surgical intervention. We do not recommend screening of the urinary tract in infants with HPS.

关键词：肥厚性幽门狭窄超声扫描超声筛查肾积水健康新生儿追踪随访临床相关性

1例Ehlers-danlos VIA患者赖氨酸羟化酶基因新突变致赖氨酸羟化酶活性下降

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世界核心医学期刊文摘（皮肤病学分册） 2005年第9期1卷 20-20页

作者： Walker L.C. Overstreet m.A. siddiqui A. H.N. Yeowell 阎小宁 Duke University medical Center Box 3135 Durham NC 27710 United States Dr.

The clinical diagnosis of a patient with the phenotype of EhlersDanlos syndrome type VI was confirmed biochemically by the severely diminished level of lysyl hydroxylase (LH) activity in the patient’s skin fibroblasts. A novel homozygous mutation, a single base change of T1360 →G in exon 13 of the LH1 gene, predicted to result in W446G, was identified in the patient’s full-length cDNA. This was confirmed in genomic DNA from both the patient and her parents, who were heterozygous for the mutation. This mutation was introduced into an LH1-pAcGP67 baculoviral construct and expressed, in parallel with normal LH1, in an insect cell system. The loss of LH activity in the mutated recombinant construct confirmed the pathogenicity of this mutation. Although not in the major catalytic site, this mutation occurs in a highly conserved region of the LH1 gene and may contribute to loss of activity by interfering with normal folding of the enzyme.

关键词：赖氨酸羟化酶突变体生化检验保存区纤维母细胞纯合子接触反应重组体临床诊断杆状病毒

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周围声掩蔽对计算机语音识别准确性的影响

国际医学放射学杂志 2009年第6期 573-573页

作者： J.Zwemer A.Lenhart W.Kim K.m.siddiqui E.L.Siegel 申小明 Department of Diagnostic Radiology and Nuclear medicine University of Maryland School of Medicine22 S Greene StBaltimoreMD 21201USA

目的评价数字阅览室内,去除伦巴(Lombard)效应影响后声掩蔽对计算机语音识别的准确度的直接效应。材料与方法本研究符合HIPAA要求,不需要伦理委员会的批准,且获得了知情同意书。10名放射学专家口述20份报告,基线时和系统声掩蔽1～4级时... 详细信息

目的评价数字阅览室内,去除伦巴(Lombard)效应影响后声掩蔽对计算机语音识别的准确度的直接效应。材料与方法本研究符合HIPAA要求,不需要伦理委员会的批准,且获得了知情同意书。10名放射学专家口述20份报告,基线时和系统声掩蔽1～4级时分别进

关键词：声掩蔽基线声性质计算机周围语音识别

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卒中介入治疗培训指南：国际多学会共识文件

国际脑血管病杂志 2017年第5期25卷 396-399页

作者： Lavine SD Cockroft K Hoh B Bambakidis N Khalessi AA Woo H Riina H siddiqui A Hirsch JA Chong W Rice H Wenderoth J mitchell P Coulthard A Signh TJ Phatorous C Khangure m Klurfan P ter Brugge K Iancu D Gunnarsson T Pongpech S Rodesch G Soderman m Taylor A Krings T Orbach D Picard L Suh DC Zheng HQ Jansen O muto m Szikora I Pierot L Brouwer P Gralla J Renowden S Andersson T Fiehler J Turjman F White P Januel AC Spelle L Kulcsar Z Chapot R Biondi A Dima S Taschner C Szajner m Krajina A Sakai N matsumaru Y Yoshknura S Ezura m Fujinaka T Iihara K Ishii A Higashi T Hirohata m Hyodo A Ito Y Kawanishi m Kiyosue H Kobayashi E Kobayashi S Kuwayama N matsumoto Y miyachi S murayama Y Nagata I Nakahara I Nemoto S Niimi Y Oishi H Satomi J Satow T Sugiu K Tanaka m Terada T Yamagami H Diaz O Lylyk P Jayaraman mV Patsalides A Gandhi CD Lee SK Abruzzo T Albani B Ansari SA Arthur AS Baxter BW Bulsara KR Chen m Almandoz JE Fraser JF Heck DV Hetts SW Hussain mS Klucznik RP Leslie-mawzi Tm mack WJ mcTaggart RA meyers Pm mocco J Prestigiacomo CA Pride GL Rasmussen PA Starke Rm Sunenshine PJ Tarr RW Frei DF Pabo m Nogueira RG Zaidat OO Jovin T Linfante I Yavagal D Liebeskind D Novakovic R Pongpech S 许岩孙瑞郭芮兵 From the American Association of Neurological Surgeons/Congress of Neurological Surgeons (AANS/CNS) Rolling Meadows IL USA American Society of Neuroradiology (ASNR) Oak Brook IL USA Asian Australasian Federation of lnterventional and Therapeutic Neuroradiology (AAFITN) Bali Indonesia Australian and New Zealand Society of Neuroradiobgy-Conjomt Committee for Recognition of Training in Interventional Neuroradiology (CCINR) representing the RANZCR (ANZSNR) ANZAN and NSA Sydney Australia Canadian Interventional Neuro Group (CING) Edmonton AB Canada World Federation of Interventional and Therapeutic Neuroradiology (WFITN) Gold Coast Australia European Society of Neuroradiology (ESNR) Milan Italy European Society of minimally Invasive Neurologic Therapy (ESmINT) Nice France Japanese Society for Neuroendovascular therapy (JSNET) Okayama Japan Sociedad Ibero Latino Americana de Neuroradiologica (SILAN) Cartagena Colombia Society of Neurolnterventional Surgery (SNIS) Washington DC USA Society of Vascular and Interventional Neurology (SVIN) Brooklyn NY USA 南京大学医学院附属金陵医院(南京军区南京总医院)神经内科 210002 解放军第一0一医院(无锡太湖医院)神经内科无锡214004

1背景缺血性卒中是全球人口死亡和残疾的首要原因。很多急性大血管闭塞（emergent large vesselocclusion，ELVO）患者都会遗留长期残疾。事实上，这些颅内大动脉闭塞经常会导致大面积脑损伤，进而造成患者死亡或严重致残。

关键词：缺血性卒中培训指南介入治疗文件学会国际血管闭塞动脉闭塞