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Nephritis Syndrom..tubulo-Intertitial and Uveitis (tinu Syndrom..: About 2 Cases

Open Journal of Nephrology 2021年第1期11卷 21-33页

作者： Hiba El Oury fatim.Zahra Jabrane kenza Bouyad Université m..am..d VI des sciences de la santé Casablanca Maroc Université Hassan II faculté de médecine et de pharmacie Casablanca Maroc

Introduction: tubular and interstitial nephropathy syndrom..with uveitis or tINU syndrom..is a rare association. Patients and m..hods: We have listed cases in which the clinical-biological picture and histology were c... 详细信息

trong>Introduction:trong> tubular and interstitial nephropathy syndrom..with uveitis or tINU syndrom..is a rare association. trong>Patients and m..hods:trong> We have listed cases in which the clinical-biological picture and histology were consistent with this syndrom.. trong>Results:trong> two cases were retained: these were two fem..e patients whose m..n age at diagnosis was 16 years. the inaugural sym..om..were bilateral anterior uveitis in two cases. the tim..to onset of renal signs: was 4 to 2 weeks m..ths. Acute kidney failure was reported in both cases with a m..n creatinine of 36.4 m..l. An average proteinuria of 1.1 g/24 h associated with aseptic leukocyturia in one case/2 and glycosuria norm..lycem.. in 1 case/2. Non inflam..tory syndrom..specific with inflam..tory anem.. is reported in both cases. kidney puncture biopsy confirm.. the diagnosis with nephropathy diffuse polym..phic tubulointerstitial and im..nofluorescence negative in both cases. Oral corticosteroid therapy (1 m..kg per day) was started for 4 to 6 m..ths. Both patients received initial local corticosteroid therapy for uveitis. the outcom..was favorable under treatm..t with rem..sion com..ete. kidney function recovered after 6 m..ths with an average serum..reatinine of 6 m..l. trong>Discussion:trong> the incidence of tINU syndrom..appears to be underestim..ed in the literature. It is believed to be an autoim..ne disease. the positive diagnosis is based on clinical, biological and histological. An etiological investigation in search of disease system.. is necessary before m..ing the diagnosis. there is no codified treatm..t. the prognosis is favorable in the m..ority of cases. trong>Conclusion:trong> Investigation of renal function is necessary for any patient.

关键词： Nephritis Syndrom..tubulo-Intertitial Uveitis tinu Syndrome

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A Severe COVID-19 Infection in Neonates: A Case Report

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Journal of Biosciences and m..icines 2021年第12期9卷 118-123页

作者： Idrissa Dem.. Ba m..am..h m..dj fatim.tall Serigne t. Ndiaye Safietou Dieye m..ham.. Fattah Am..ou Sow Ndeye F. Sow Awa kane Aita Seck Am..ata m..ye Alioune m..Coundoul khadim..op Pape S. Sow Am..ou L. Fall Papa m..Faye Ousm..e Ndiaye Albert Royer National Children Hospital Dakar Senegal Cheikh Anta DIOP University Dakar Senegal Abass Ndao Hospital Center Dakar Senegal

Coronavirus disease (COVID-19) is a highly contagious infectious disease. First case was reported at the end of 2019 in China. Children and neonate population appears to be relatively free of the virus. We reported a severe and fatal neonate case of COVID-19 in a 22 days old neonate fem..e due to the delta variant strain during the third wave outbreak. She presented with fever, cough, grunting and diarrhea started 5 days before adm..sion. Physical exam.. revealed severe respiratory distress, hypoxia and bilateral pulm..ary condensation. PCR test for COVID-19 was positive. Chest X-ray found bilateral infiltrates. Chest Ct showed diffuse ground glass im..es with 75% of lung parenchym.. involvem..t. She was treated with antibiotics, corticostoid, respiratory support (CPAP and oxygen). Death occurred after 15 days of hospitalization in the context of m..tiple organ failure and pulm..ary hypertension.

关键词： COVID-19 Hypoxia Newborn Variant Delta Senegal

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