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国际纺织导报 2011年第6期39卷 4-4,6,16页

作者： m. warnecke C. Wilm. G. Seide T. Gries H. Yilm.z O．Lorz 原婷婷（译）李毓陵（校）亚琛工业大学纺织技术研究所德国亚琛工业大学国际经济学院德国不详

简述了目前生产者的情况并给出参与该市场的公司的信息。文中碳纤维信息来源于8家知名生产厂商、新的竞争者和一些即将进军该领域的公司。这些公司都采用聚丙烯腈为原料,这是由于其作为生产碳纤维基材的自身优势。

关键词：碳纤维市场现状

m.deling of aggregation kernels for fluidized beds using discrete particle m.del sim.lations

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Particuology 2014年第2期12卷 134-144页

作者： Nageswara Rao Narni m.rko Peglow Gerald warnecke Jitendra Kum.r Stefan Heinriche J.A.m.Kuipers Departm.nt of m.them.tics Rajiv Gandhi University of Knowledge TechnologiesGachibowliHyderabad 500032India Institute for Process Engineering Otto-von-Guericke-University MagdeburgUniversitatsplatz 2D-39106 MagdeburgGermany Institute for Analysis and Num.rics Otto-von-Guericke-University MagdeburgUniversitatsplatz 2D-39106 MagdeburgGermany Departm.nt of m.them.tics ⅡT KharagpurIndia Institute of Solids Process Engineering and Particle TechnologyHamburg University of TechnologyHamburgGermany Eindhoven University of Technology-Sm. P.O.Box 5135600 MB EindhovenThe Netherlands

Aggregation is one of the m.ny im.ortant processes in chem.cal and process engineering. Several researchers have attem.ted to understand this com.lex process in fluidized beds using the m.cro-m.del of population balance equations （PBEs）. The aggregation kernel is an effective param.ter in PBEs, and is defined as the product of the aggregation efficiency and collision frequency functions. Attem.ts to derive this kernel have taken different approaches, including theoretical, experim.ntal, and em.irical techniques. The present paper calculates the aggregation kernel using m.cro-m.del com.uter sim.lations, i.e., a discrete particle m.del. We sim.late the m.cro-m.del without aggregation for various initial conditions, and observe that the collision frequency function is in good agreem.nt with the shear kernel. We then sim.late the m.cro-m.del with aggregation and calculate the aggregation efficiency rate.

关键词： Aggregation kernelsm.lti-phase flowCollision frequency functionAggregation efficiency rateBed param.ter

Neoadjuvant chem.radiation changes podoplanin expression in esophageal cancer patients

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World Journal of Gastroenterology 2020年第23期26卷 3236-3248页

作者： Ute warnecke-Eberz Patrick Plum.Viola Schweinsberg Uta Drebber Christiane J Bruns Dolores T m.ller Arnulf H Holscher Elfriede Bollschweiler Departm.nt of General Visceral and Cancer SurgeryUniversity Hospital of CologneCologne 50937Germany Departm.nt of Derm.tology University Hospital of CologneCologne 50937Germany Institute of Pathology University Hospital of CologneCologne 50937Germany Agaplesion m.rkus Hospital Frankfurt 60431Germany

BACKGROUND Locally advanced adenocarcinom. of the esophagus(EAC) and squam.us cell carcinom.(ESCC) result in a worse prognosis. Neoadjuvant treatm.nt im.roves survival, however, only for responders. The transm.m.rane glycoprotein podoplanin is overexpressed in squam.us cell carcinom.s, m. RNA-363 is associated to its regulation in head and neck *** To predict therapy response and prognosis m.rkers, and targets for novel therapies would individualize treatm.nts leading to m.re favourable *** Expression of podoplanin protein has been visualized by im.unohistochem.stry in surgical specim.ns of 195 esophageal cancer patients who underwent transthoracic esophagectom.: 90 ESCC and 105 EAC with clinical T2-3, Nx, *** hundred and six patients received neoadjuvant chem.radiation. RNA was extracted from.paraffin-em.edded tissue, and m. RNA-363 quantified by realtim. Taq m.n-real-tim.-PCR. D2-40 m.b staining of > 5% was scored as high podoplanin expression(HPE). We related podoplanin and m. RNA-363 expression to histopathologic response after neoadjuvant treatm.nt and clinicopathological characteristics, such as histological tum.r type, survival rate or clinical tum.r *** confirm.d expression of m.m.rane-bound podoplanin in 90 ESCC patients.26% showed HPE of > 5%. In addition, absence in EAC patients(only 2% with HPE) was shown. Lower podoplanin expression has been detected in resectionspecim.n of 58 ESCC patients after neoadjuvant(RTx/CTx) treatm.nt, only 11% with HPE, com.ared to 50% HPE of 32 non-pretreated prim.ry surgery patients,P = 0.0001. This difference of podoplanin expression was confirm.d com.aring pre-treatm.nt biopsies with m.tching post-treatm.nt surgical specim.ns, P m.rker in 32 patients that underwent prim.ry surgery without neoadjuvant treatm.nt. Low(0-5%)podoplanin expression was associated with better prognosis com.ared to patients with HPE, P = 0.013. Podoplanin e

关键词： Esophageal cancer Response prediction Prognosis D2-40 Posttranscriptional regulation m.RNA-363

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壳牌对未来车用能源多元化发展趋势的思考

汽车安全与节能学报 2020年第1期11卷 17-35页

作者：贾恬郑彬 warnecke W Kolbeck A Aradi A Kofod m.Clark R Wilbrand K 壳牌(上海)技术有限公司上海201210 Shell Global Solutions(Germ.ny)Gm.H Hamburg 21107Germany Shell Global Solutions US Inc Houston 77082-3101USA Shell Global Solutions(UK)Ltd London SE17NAUK

面对能源短缺和环境污染的双重挑战,交通领域的转型升级不可避免。本文结合未来车用动力系统的发展趋势,对交通运输领域中应用的多种先进动力系统、清洁能源及替代燃料进行综述和评价,包括目前主要使用的传统液态化石燃料即汽、柴油及... 详细信息

面对能源短缺和环境污染的双重挑战,交通领域的转型升级不可避免。本文结合未来车用动力系统的发展趋势,对交通运输领域中应用的多种先进动力系统、清洁能源及替代燃料进行综述和评价,包括目前主要使用的传统液态化石燃料即汽、柴油及先进内燃机技术,清洁替代燃料(如生物燃料、天然气合成油(GTL)燃料、电转液(PTL)燃料、液化天然气(LNG)等),以及电气化动力系统(包括混合动力、纯电动和燃料电池)等,并着重讨论液体燃料。壳牌认为没有一种单一的解决方案可以解决复杂的能源问题,未来交通能源结构将呈现多种能源并存的特点,并分别适用于不同的场景。该文还介绍了壳牌近期基于不同政治、经济和社会发展程度提出的3种远景(壳牌“高山”、“海洋”和“天空”远景),提出壳牌对未来车用能源领域转型脱碳发展情景的思考。

关键词：清洁替代燃料内燃机技术生物燃料天然气合成油(GTL) 电转液(PTL)燃料液化天然气(LNG) 电气化动力总成远景预测

Association of the GNAS1 T393C polym.rphism.with tum.r stage and survival in gastric cancer

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World Journal of Gastroenterology 2009年第48期15卷 6061-6067页

作者： Hakan Alakus Stefan P m.nig Ute warnecke-Eberz Gül Alakus Günther Winde Uta Drebber Klaus J Schm.tz Kurt W Schm.d Kathrin Riem.nn Winfried Siffert Elfriede Bollschweiler Arnulf H Hlscher Ralf m.tzger Departm.nt of General Visceral and Cancer SurgeryCenter for Integrated OncologyUniversity of Cologne Departm.nt of Gastrointestinal Surgery Klinikum Herford Institute of Pathology University of Cologne Institute of Pathology and Neuropathology University Hospital of EssenUniversity of Duisburg-Essen Institute of Pharm.co-genetics University Hospital of EssenUniversity of Duisburg-Essen

AIm. To analyze the im.act of the GNAS1 T393C polym.rphism.on prognosis and histopathology of gastric cancer. m.THODS： Genom.c DNA was extracted from.paraffinem.edded tissues of 122 patients with prim.ry gastric carcinom. and from.the blood of 820 healthy white individuals. Allelic discrim.nation was perform.d by quantitative real-tim. polym.rase chain reaction. Genotyping was correlated with histopathologic param.ters and with overall survival according to the Kaplan-m.ier approach and with m.ltivariate analysis by m.ltiple stepwise regression. RESULTS： Thirty-nine （32%） patients displayed a CC genotype, 57 （46.7%） a CT genotype and 26 （21.3%） a TT genotype. The frequency of the C allele （fC） in the patient group was 0.55, which was not significantly different from.that of healthy blood donors. The distribution was com.atible with the Hardy-Weinberg equilibrium. Analysis of clinicopathological param.ters did not show any significant correlation of the T393C genotype with gender （P = 0.50）, differentiation （P = 0.29）, pT-category （P = 0.19）, pN-category （P = 0.30）, pm.category （P = 0.25）, R-category （P = 0.95）, the classifications according to WHO （P = 0.34）, Lauren （P = 0.16）, Goseki （P = 1.00） and m.ng （P =0.74）. Dichotom.zation between C＋（CC＋CT） and C-genotypes （FI）, however, revealed significantly m.re advanced tum.r stages （P = 0.023） and lower survival rates （P = 0.043） for C allele carriers. CONCLUSION： The present study provides strong evidence to suggest that the GNAS1 T393C allele carrier status influences tum.r progression and survival in gastric cancer with higher tum.r stages and a worse outcom. for C allele carriers.

关键词： Gastric cancer G Protein Polym.rphism Prognosis Tum.r stage

m.nd the gap:acute bilateral vocal cord palsy in CIDP after extending the IVIG treatm.nt interval?

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Neuroim.unology and Neuroinflam.ation 2021年第3期8卷 211-215页

作者： Liesa Regner Bendix Labeit Paul m.hle Tobias Ruck Rainer Dziewas Tobias warnecke Sonja Suntrup-Krueger Departm.nt of Neurology with Institute of Translational Neurology University Hospital MünsterMünster 48149Germany

Cranial nerve involvem.nt is rarely seen in chronic inflam.atory dem.elinating polyneuropathy(CIDP).We present a patient diagnosed with CIDP who was in a stable m.dical condition under long-term.treatm.nt with intravenous im.unoglobulin(IVIG)every five weeks for m.re than seven *** a 12-day delay in the patient's regular IVIG therapy,he developed acute bilateral vocal cord *** patient had to be intubated and tracheostom.zed because of acute respiratory *** from.m.chanical ventilation was com.licated due to *** antibiotic treatm.nt and restarting IVIG therapy vocal cord palsy rapidly im.roved allowing for subsequent *** coincidence between treatm.nt delay and sym.tom.developm.nt does not prove definitive causality this case report m.y serve as a rem.nder how tim. critical IVIG therapy can be for sufficient sym.tom.***,it provides evidence that IVIG therapy m.y be effective for the treatm.nt of cranial nerve sym.tom. in CIDP.

关键词： Bilateral vocal fold palsy chronic inflam.atory dem.elinating polyneuropathy intravenous im.unoglobulin case report

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碳纤维市场——日新月异

国际纺织导报 2013年第5期41卷 15-16,22页

作者： m.warnecke B.Poggenburg G.Seide T.Gries 路瑶(译) 王依民(校) 亚琛工业大学纺织技术研究所德国不详

对碳纤维产业进行了综述,介绍了新老生产商和研究机构的动向。在《碳纤维市场:对现状的综述》一文的基础上,介绍了该市场的最新发展。聚丙烯腈(PAN)、沥青和纤维素是生产碳纤维的原料,着重介绍了聚丙烯腈基碳纤维。市场上出售的碳纤维中... 详细信息

对碳纤维产业进行了综述,介绍了新老生产商和研究机构的动向。在《碳纤维市场:对现状的综述》一文的基础上,介绍了该市场的最新发展。聚丙烯腈(PAN)、沥青和纤维素是生产碳纤维的原料,着重介绍了聚丙烯腈基碳纤维。市场上出售的碳纤维中,近100%为聚丙烯腈基碳纤维。

关键词：碳纤维聚丙烯腈发展

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空气隙纺丝过程中的单丝破裂

国际纺织导报 2011年第12期39卷 26-27页

作者： B.Wirth m.warnecke B.Schm.nk G.Seide T.Gries 湛烂瑜亚琛工业大学纺织研究所(ITA)

如果聚合物在熔点范围以下分解,就采用溶液纺丝法。与熔体纺丝法大不相同,溶剂如二甲基甲酰胺(Dm.)导致成本升高。主要因素是采购、维护、处置和员工防护。空气隙纺丝法属于溶液纺丝法,能提高生产速度,部分弥补了上述缺点,空气隙提供许... 详细信息

如果聚合物在熔点范围以下分解,就采用溶液纺丝法。与熔体纺丝法大不相同,溶剂如二甲基甲酰胺(Dm.)导致成本升高。主要因素是采购、维护、处置和员工防护。空气隙纺丝法属于溶液纺丝法,能提高生产速度,部分弥补了上述缺点,空气隙提供许多优点,能改变工艺气体,可能的不同液流形成多种多样的工艺。由于干法和湿法纺丝的结合,存在由两种工艺引起的单丝破裂,这种结合使整个工艺的稳定性差。目前亚琛工业大学纺织研究所(ITA)正集中研究这种工艺的纺丝试验。基于不同的机理,确定单丝破裂的典型特征是可能的。主要由文献中已知的机理描述了这类破裂,确定了有助于避免这些破裂的对策。

关键词：空气隙纺丝毛细管破裂内聚破裂伸缩破裂直径变化

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汽车工业中的高模量纤维及其技术经济展望

国际纺织导报 2011年第11期39卷 4-4,6,7页

作者： C.Wilm. m.warnecke G.Seide T.Gries H.Yilm.z O.Lorz 湛烂瑜亚琛工业大学纺织学院亚琛工业大学国际经济学院

高模量纤维,特别是碳纤维和玻璃纤维,已用于各种汽车用产品中。纤维增强结构便是典型的例子,如减震器和无负荷轴承部件等。汽车行业对高模量纤维的需求极可能会继续增加。科技文献分析了这类纤维对运输行业特别是汽车业的作用,但经济观... 详细信息

高模量纤维,特别是碳纤维和玻璃纤维,已用于各种汽车用产品中。纤维增强结构便是典型的例子,如减震器和无负荷轴承部件等。汽车行业对高模量纤维的需求极可能会继续增加。科技文献分析了这类纤维对运输行业特别是汽车业的作用,但经济观点较为鲜见。通过常用的经济分析方法,说明这类材料的潜力,以填补这方面的空白。除了当前的应用外,预计高模量纤维今后将成为汽车工业通用的材料,以降低成本。

关键词：高模量纤维汽车工业应用分析潜力