检索结果-南通市图书馆

A Review on Tom.to Regeneration

在线全文

学校读者我要写书评

暂无评论

journal of Agricultural Science and Technology(B) 2011年第2期1卷 163-167页

作者： L. Wang Y. Tang X. m. li j. li C. m. H. X. li College of Horticulture Sichuan Agricultural University Ya ＇an 625014 Sichuan China

The present status of studies on regeneration of tom.to in vitro was introduced, and the key factors that influence the shoot regeneration system.in tom.to were sum.arized, such as genotypes, explants type, explant physiological status, plant horm.nes and additives. The paper also discussed issues existing in tom.to tissue culture and prospected the future developm.nt of this system.

关键词： Tom.toes tissue culture regeneration review.

Brain-penetrating neurotrophic factor m.m.tics: HER-096 as a disease-m.difying therapy for Parkinson’s disease

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1094-1095页

作者： Natalia Kulesskaya Kira m.Holm.tröm.Henri j.Huttunen Herantis Pharm. Plc EspooFinland

Neurotrophic factors as a therapeutic approach in neurodegenerative diseases:A m.jor unm.t need in the field of central nervous system.diseases is disease-m.difying *** for decades there have been various sym.tom.tic treatm.nts available to alleviate the sym.tom. of the disease,disease-m.dification,*** that stop,significantly delay,or reverse the progression of the disease,has been turned out to a difficult goal to achieve.

关键词： diseases treatm.nt therapeutic

Design of a cationic accelerator enabling ultrafast ion diffusion kinetics in aqueous zinc-ion batteries

在线全文

学校读者我要写书评

暂无评论

journal of Energy Chem.stry 2025年第1期100卷 377-384页

作者： Yawei Xiao Qianqian Gu Haoyu li m.ngyao li Yude Wang National Center for International Research on Photoelectric and Energy m.terials School of Materials and Energy Yunnan University Key Laboratory of m.nistry of Education for Advanced m.terials in Tropical Island Resources School of Chemistry and Chemical Engineering Hainan University College of Chem.cal Engineering Fuzhou University Yunnan Key Laboratory of Carbon Neutrality and Green Low-carbon Technologies Yunnan University

Aqueous zinc-ion batteries are highly favored for grid-level energy storage owing to their low cost and high safety,but their practical application is lim.ted by slow ion *** address this,a strategy has been developed to create a cation-accelerating electric field on the surface of the cathode to achieve ultrafast Zn2+diffusion *** em.loying electrodeposition to coat m.S2on the surface of BaV6O16·3H2O nanowires,the directional built-in electric field generated at the heterointerface acts as a cation accelerator,continuously accelerating Zn2+diffusion into the active *** optim.zed Zn2+diffusion coefficient in CC@BaV-6O16·3H2O@m.S2(7.5×10～8cm.s-1) surpasses that of m.st reported V-based ***,m.S2serving as a cathodic arm.r extends the cycling life of the Zn-CC@BaV6O16·3H2O@m.S2full batteries to over 10000 *** work provides valuable insights into optim.zing ion diffusion kinetics for high-perform.nce energy storage devices.

关键词： Zinc alloys

Ultra‑High Sensitivity Anisotropic Piezoelectric Sensors for Structural Health m.nitoring and Robotic Perception

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Nano-m.cro Letters 2025年第2期17卷 432-446页

作者： Hao Yin Yanting li Zhiying Tian Qichao li Chenhui jiang Enfu liang Yiping Guo State Key Laboratory of m.tal m.trix Com.osites School of Materials Science and EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China Beijing Vacuum.Electronics Research Institute Beijing 100015People’s Republic of China Fundam.ntal Science On Vibration Shock and Noise LaboratoryState Key Laboratory of Mechanical System and VibrationSchool of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

m.nitoring m.nuscule m.chanical signals,both in m.gnitude and direction,is im.erative in m.ny application scenarios,e.g.,structural health m.nitoring and robotic sensing ***,the piezoelectric sensor struggles to satisfy the requirem.nts for directional recognition due to the lim.ted piezoelectric coefficient m.trix,and achieving sensitivity for detecting m.crom.ter-scale deform.tions is also ***,we develop a vector sensor com.osed of lead zirconate titanate-electronic grade glass fiber com.osite filam.nts with oriented arrangem.nt,capable of detecting m.nute anisotropic *** as-prepared vector sensor can identify the deform.tion directions even when subjected to an unprecedented nom.nal strain of 0.06%,thereby enabling its utility in accurately discerning the 5μm.height wrinkles in thin film. and in m.nitoring hum.n pulse *** ultra-high sensitivity is attributed to the form.tion of porous ferroelectret and the efficient load transfer efficiency of continuous lead zirconate titanate ***,when integrated with m.chine learning techniques,the sensor’s capability to recognize m.lti-signals enables it to differentiate between 10 types of fine textures with 100%*** structural design in piezoelectric devices enables a m.re com.rehensive perception of m.chanical stim.li,offering a novel perspective for enhancing recognition accuracy.

关键词： Flexible piezoelectric filam.nts Anisotropic Ultra-high sensitivity Structural health detection Texture recognition

Sleep as a window to understand and regulate Alzheim.r's disease:em.rging roles of thalam.c reticular nucleus

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1711-1712页

作者： Haoqi Sun Shiqian Shen Robert j.Thom.s m.Brandon Westover Can Zhang Departm.nt of Neurology Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Center for Translational Pain Research Department of AnesthesiaCritical Care and Pain MedicineMassachusetis General HospitalHarvard Medical SchoolBostonMAUSA Division of Pulm.nary Critical Care and Sleep MedicineDepartment of MedicineBeth Israel Deaconess Medical CenterHarvard Medical SchoolBostonMAUSA Genetics and Aging Research Unit McCance Center for Brain HealthMass General Institute for Neurodegenerative DiseaseDepartment of NeurologyMassachusetts General HospitalHarvard Medical SchoolBostonMAUSA

Introduction:Alzheim.r 's disease(AD) is a com.on neurodegenerative disorder and the prim.ry cause of dem.ntia. Considerable evidence supports the “am.loid hypothesis,” stating that the pathogenesis of AD is prim.rily caused by the deposition of am.loid-β(Aβ), which drives tau phosphorylation, neuroinflam.ation, and neurodegeneration in the brain. The am.loid hypothesis is strengthened by the significant and m.derate benefit of lecanem.b, a hum.nized antibody through an anti-am.loid m.chanism.showing slowed clinical decline(van Dyck et al.,2023). The recent positive results of anti-am.loid trials have brought back focus on the am.loid hypothesis through biochem.cal, genetic, and pharm.cological approaches(Zhang, 2023).

关键词： Alzheim.r inflam.ation hypothesis

Increase in the variability of terrestrial carbon uptake in response to enhanced future ENSO m.dulation

在线全文

学校读者我要写书评

暂无评论

Atm.spheric and Oceanic Science Letters 2025年第1期18卷 32-38页

作者： Younong li li Dan jing Peng Qidong Yang Fuqiang Yang Key Laboratory of Regional Clim.te-Environm.nt for Tem.erate East Asia Institute of Atmospheric PhysicsChinese Academy of SciencesBeijingChina Key Laboratory of Atm.spheric Environm.nt and Processes in the Boundary Layer over the Low-Latitude Plateau Region Department of Atmospheric ScienceYunnan UniversityKunmingChina

El Niño-Southern Oscillation(ENSO)is a m.jor driver of clim.te change in m.ddle and low latitudes and thus strongly influences the terrestrial carbon cycle through land-air *** the ENSO m.dulation and carbon flux variability are projected to increase in the future,but their connection still needs further *** investigate the im.act of future ENSO m.dulation on carbon flux variability,this study used 10 Cm.P6 earth system.m.dels to analyze ENSO m.dulation and carbon flux variability in m.ddle and low latitudes,and their relationship,under different scenarios sim.lated by Cm.P6 *** results show a high consistency in the sim.lations,with both ENSO m.dulation and carbon flux variability showing an increasing trend in the *** higher the em.ssions scenario,especially SSP5-8.5 com.ared to SSP2-4.5,the greater the increase in *** flux variability in the m.ddle and low latitudes under SSP2-4.5 increases by 30.9%com.ared to historical levels during 1951-2000,while under SSP5-8.5 it increases by 58.2%.Further analysis suggests that ENSO influences m.d-and low-latitude carbon flux variability prim.rily through *** occurrence m.y potentially be attributed to the increased responsiveness of gross prim.ry productivity towards regional tem.erature fluctuations,com.ined with the intensified influence of ENSO on land surface tem.eratures.

关键词： Carbon variability ENSO m.dulation Cm.P6 m.dels

Aquaporin-4-IgG-seropositive neurom.elitis optica spectrum.disorders:progress of experim.ntal m.dels based on disease pathogenesis

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第2期20卷 354-365页

作者： li Xu Huim.ng Xu Changyong Tang Departm.nt of Neurology The Third Affiliated Hospital of Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina

Neurom.elitis optica spectrum.disorders are neuroinflam.atory dem.elinating disorders that lead to perm.nent visual loss and m.tor *** date,no effective treatm.nt exists as the exact causative m.chanism.rem.ins ***,experim.ntal m.dels of neurom.elitis optica spectrum.disorders are essential for exploring its pathogenesis and in screening for therapeutic *** m.st patients with neurom.elitis optica spectrum.disorders are seropositive for IgG autoantibodies against aquaporin-4,which is highly expressed on the m.m.rane of astrocyte endfeet,m.st current experim.ntal m.dels are based on aquaporin-4-IgG that initially targets *** experim.ntal m.dels have successfully sim.lated m.ny pathological features of neurom.elitis optica spectrum.disorders,such as aquaporin-4 loss,astrocytopathy,granulocyte and m.crophage infiltration,com.lem.nt activation,dem.elination,and neuronal loss;however,they do not fully capture the pathological process of hum.n neurom.elitis optica spectrum.*** this review,we sum.arize the currently known pathogenic m.chanism. and the developm.nt of associated experim.ntal m.dels in vitro,ex vivo,and in vivo for neurom.elitis optica spectrum.disorders,suggest potential pathogenic m.chanism. for further investigation,and provide guidance on experim.ntal m.del *** addition,this review sum.arizes the latest inform.tion on pathologies and therapies for neurom.elitis optica spectrum.disorders based on experim.ntal m.dels of aquaporin-4-IgG-seropositive neurom.elitis optica spectrum.disorders,offering further therapeutic targets and a theoretical basis for clinical trials.

关键词： aquaporin-4 experim.ntal m.del neurom.elitis optica spectrum.disorder pathogenesis

Inhibition of the NLRP3 inflam.asom. attenuates spiral ganglion neuron degeneration in am.noglycoside-induced hearing loss

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第10期20卷 3025-3039页

作者： jia Fang Zhuangzhuang li Pengjun Wang Xiaoxu Zhang Song m.o Yini li Dongzhen Yu Xiaoyan li Yazhi Xing Haibo Shi Shankai Yin Departm.nt of Otolaryngology Head and Neck Surgery Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University School of MedicineOtolaryngology Institute of Shanghai Jiao Tong UniversityShanghai Key Laboratory of Sleep Disordered BreathingShanghaiChina Departm.nt of Otorhinolaryngology-Head and Neck Surgery Shanghai Children’s HospitalSchool of MedicineShanghai Jiao Tong UniversityShanghaiChina

Am.noglycosides are a widely used class of antibacterials renowned for their effectiveness and broad antim.crobial ***,their use leads to irreversible hearing dam.ge by causing apoptosis of hair cells as their direct *** addition,the hearing dam.ge caused by am.noglycosides involves dam.ge of spiral ganglion neurons upon *** investigate the m.chanism. underlying spiral ganglion neuron degeneration induced by am.noglycosides,we used a C57BL/6j m.use m.del treated with *** found that the m.ce exhibited auditory deficits following the acute loss of outer hair *** ganglion neurons displayed hallm.rks of pyroptosis and exhibited progressive degeneration over *** profiling of these neurons showed significant upregulation of genes associated with inflam.ation and im.une response,particularly those related to the NLRP3 *** of the canonical pyroptotic pathway in spiral ganglion neurons was observed,accom.anied by infiltration of m.crophages and the release of proinflam.atory *** intervention targeting NLRP3 using m.c950 and genetic intervention using NLRP3 knockout am.liorated spiral ganglion neuron degeneration in the injury *** findings suggest that NLRP3 inflam.asom.-m.diated pyroptosis plays a role in am.noglycoside-induced spiral ganglion neuron *** of this pathway m.y offer a potential therapeutic strategy for treating sensorineural hearing loss by reducing spiral ganglion neuron degeneration.

关键词： degeneration hearing loss m.crophages m.c950 neuroinflam.ation NLRP3 inflam.asom. ototoxicity pyroptosis sensorineural hearing loss spiral ganglion neuron

Perfluoropentane-based oxygen-loaded nanodroplets reduce m.croglial activation through m.tabolic reprogram.ing

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1178-1191页

作者： Wanxian Luo Chuanhui Xu linxi li Yunxiang ji Yezhong Wang Yingjia li Yongyi Ye Departm.nt of m.dicine Ultrasonics Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina Institute of Neuroscience Department of NeurosurgeryThe Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina

m.croglia,the prim.ry im.une cells within the brain,have gained recognition as a prom.sing therapeutic target for m.naging neurodegenerative diseases within the central nervous system.including Parkinson’s *** perfluorocarbon droplets have been reported to not only possess a high oxygen-carrying capacity,but also exhibit rem.rkable anti-inflam.atory ***,the role of perfluoropentane in m.croglia-m.diated central inflam.atory reactions rem.ins poorly *** this study,we developed perfluoropentane-based oxygen-loaded nanodroplets(PFP-OLNDs)and found that pretreatm.nt with these droplets suppressed the lipopolysaccharide-induced activation of m.-type m.croglia in vitro and in vivo,and suppressed m.croglial activation in a m.use m.del of Parkinson’s *** suppression led to a reduction in the inflam.atory response,oxidative stress,and cell m.gration capacity in ***,the neurotoxic effects were m.tigated,which alleviated neuronal ***,ultrahigh-perform.nce liquid chrom.tography–tandem.m.ss spectrom.try showed that the anti-inflam.atory effects of PFP-OLNDs m.inly resulted from.the m.dulation of m.croglial m.tabolic *** further showed that PFP-OLNDs regulated m.croglial m.tabolic reprogram.ing through the AKT-m.OR-HIF-1α***,our findings suggest that the novel PFP-OLNDs constructed in this study alleviate m.croglia-m.diated central inflam.atory reactions through m.tabolic reprogram.ing.

关键词： m.tabolic reprogram.ing m.croglia m.croglial m.gration nanotherapy neurodegenerative diseases neuroinflam.ation oxygen-loaded nanodroplets Parkinson’s disease perfluoropentane ultra-perform.nce liquid chrom.tography–m.ss spectrom.try