检索结果-南通市图书馆

Enhancing Pneum.nia Detection in Pediatric Chest X-Rays Using CGAN-Augm.nted Datasets and Lightw.ight Deep Transfer Learning m.dels

引用

Journal of Data Analysis and Inform.tion Processing 2024年第1期12卷 1-23页

作者： Coulibaly m.ham.d Ronald w.w.ru m.angi John m. Kihoro Departm.nt of m.them.tics Pan African University Institute for Basic Sciences Technology and Innovation (PAUSTI) Nairobi Kenya Departm.nt of Com.uting Jomo Kenyatta University of Agriculture and Technology Nairobi Kenya School of Com.uting and m.them.tics The Cooperative University of Kenya Nairobi Kenya

Pneum.nia ranks as a leading cause of m.rtality, particularly in children aged five and under. Detecting this disease typically requires radiologists to exam.ne chest X-rays and report their findings to physicians, a task susceptible to hum.n error. The application of Deep Transfer Learning (DTL) for the identification of pneum.nia through chest X-rays is hindered by a shortage of available im.ges, w.ich has led to less than optim.l DTL perform.nce and issues w.th overfitting. Overfitting is characterized by a m.del’s learning that is too closely fitted to the training data, reducing its effectiveness on unseen data. The problem.of overfitting is especially prevalent in m.dical im.ge processing due to the high costs and extensive tim. required for im.ge annotation, as w.ll as the challenge of collecting substantial datasets that also respect patient privacy concerning infectious diseases such as pneum.nia. To m.tigate these challenges, this paper introduces the use of conditional generative adversarial netw.rks (CGAN) to enrich the pneum.nia dataset w.th 2690 synthesized X-ray im.ges of the m.nority class, aim.ng to even out the dataset distribution for im.roved diagnostic perform.nce. Subsequently, w. applied four m.dified lightw.ight deep transfer learning m.dels such as Xception, m.bileNetV2, m.bileNet, and EfficientNetB0. These m.dels have been fine-tuned and evaluated, dem.nstrating rem.rkable detection accuracies of 99.26%, 98.23%, 97.06%, and 94.55%, respectively, across fifty epochs. The experim.ntal results validate that the m.dels w. have proposed achieve high detection accuracy rates, w.th the best m.del reaching up to 99.26% effectiveness, outperform.ng other m.dels in the diagnosis of pneum.nia from.X-ray im.ges.

关键词： Pneum.nia Detection Pediatric Radiology CGAN (Conditional Generative Adversarial Netw.rks) Deep Transfer Learning m.dical Im.ge Analysis

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The Protective Effect of m.ringa oleifera Leaves Extract on Paracetam.l Hepatotoxicity in m.le Rats

引用

Journal of Biom.dical Science and Engineering 2024年第3期17卷 72-82页

作者： Reham.m. Al-Sultan Noorah Saleh Al-Sow.yan Departm.nt of Biology College of Science Qassim University Buraydah Saudi Arabia

In recent years, there has been an increase in concern regarding the effects of paracetam.l poisoning on liver tissues, particularly w.en consum.d in large am.unts. Som. studies have estim.ted that paracetam.l is involved in 56% of acute liver diseases, w.ereas 0.4% of paracetam.l overdose cases result in fatal-ity. In this study, the effects of m.ringa oleifera on paracetam.l toxicity in the liver w.re explored. It has been dem.nstrated that m.ringa oleifera is highly nu-tritious, contains bioactive m.lecules, and is therapeutically beneficial. m.ny studies have show. that m.ringa oleifera leaves possess a w.de range of biologi-cal properties, including antioxidant, tissue protection, analgesic, antihyperten-sive, and im.unom.dulatory activities. This study highlights the protective role of m.ringa oleifera on handling possible paracetam.l hepatotoxicity in m.le rats. .

关键词： m.ringa oleifera Paracetam.l Hepatotoxicity Oxidative Stress

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Analysis and Review.of Dow.regulated Actin Cytoskeletal Proteins in Non-Sm.ll Cell Lung Cancer

引用

Journal of Biosciences and m.dicines 2024年第4期12卷 89-115页

作者： Hala m. Abdel m.geed Praveen Sahu Raji Sundararajan School of Engineering Technology Purdue University West Lafayette USA National Institute of Standards Al Haram Egypt

Actin, a highly conserved protein, plays a dom.nant role in Non-sm.ll cell lung cancer (NSCLC). Late diagnosis and the aggressive nature of NSCLC pose a significant threat. Studying the clinic pathological properties of NSCLC proteins is a potential alternative for developing treatm.nt strategies. Tow.rds this, 35 dow.regulated actin cytoskeletal proteins on NSCLC prognosis and treatm.nt w.re studied by exam.ning their protein-protein interactions, gene ontology enrichm.nt term., and signaling pathw.ys. Using Pubm.d, various proteins in NSCLC w.re identified. The protein-protein interactions and functional associations of these proteins w.re exam.ned using the STRING database. The focal adhesion signaling pathw.y w.s selected from.all available KEGG and w.ki pathw.ys because of its role in regulating gene expression, facilitating cell m.vem.nt and reproduction, and significantly im.acting NSCLC. The protein-protein interaction netw.rk of the 35 dow.regulated actin cytoskeleton proteins revealed that ACTG1, ACTR2, ACTR3, ANXA2, ARPC4, FLNA, TLN1, CALD1, m.L6, m.H9, m.H10, TPm., TPm., TPm., PFN1, IQGAP1, m.N, and ZXY exhibited the highest num.er of interactions. w.ereas HSPB1, CTNNA1, KRT17, KRT7, FLNB, SEPT2, and TUBA1B displayed m.dium.interactions, w.ile UTRN, TUBA1B, and DUSP23 had relatively few.r interactions. It w.s discovered that focal adhesions are critical in connecting m.m.rane receptors w.th the actin cytoskeleton. In addition, protein kinases, phosphatases, and adapter proteins w.re identified as key signaling m.lecules in this process, greatly influencing cell shape, m.tility, and gene expression. Our analysis show. that the focal adhesion pathw.y plays a crucial role in NSCLC and is essential for developing effective treatm.nt strategies and im.roving patient outcom.s.

关键词： Non-Sm.ll Cell Lung Cancer NSCLC Actin Actin Cytoskeletal Proteins Focal Adhesion KEEG Pathw.y

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A Study of Radiation-Induced Telom.re Instability Using m.ltiplex Ligation-Dependent Probe Am.lification (m.PA)

引用

Advances in Biological Chem.stry 2024年第3期14卷 73-85页

作者： Alan Chant Ahm.d Chaudary Christina m. Kraem.r-Chant Departm.nt of m.crobiology and m.lecular Genetics University of Vermont Burlington VT USA Departm.nt of Public and Allied Health Bowling Green State University Bowling Green OH USA Departm.nt of Chem.stry Saint Michaels College Colchester VT USA

The integrity of the chrom.som.s for tw. w.L2-derived lym.hoblastoid cell lines (TK6 and w.K1) in the presence and absence of ionizing radiation w.s analyzed by m.ltiplex Ligation-Dependent Probe Am.lification (m.PA). The TK6 cell line has the native p53 tum.r-suppressor gene, w.ereas w.K1 cells contain a p53 m.tation. Each cell line w.s isolated pre- and post-irradiation (2 and 3 Gy) and analyzed by m.PA. The im.act of irradiation on these tw. cell lines w.s investigated using probes that target specific regions on chrom.som.s associated w.th subtelom.ric regions. Results indicate that w.K1 and TK6 are im.acted differently after irradiation, and that each cell line presents its ow. unique m.PA profile. The m.st notable differences are the appearance of a num.er of probes in the post-irradiated m.PA profile that are not present in the controls, and tw. unique probe signals only seen in w.K1 cells. These results build on our previous studies that indicate how.different hum.n cell lines can be affected by radiation in significantly different w.ys depending on the presence or absence of w.ld type p53.

关键词： Ionizing Radiation m.ltiplex Ligation-Dependent Probe Am.lification (m.PA) p53 Tum.r Suppressor Telom.re Instability

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Strategic Planning Practices of Hotels in Kenya

引用

Journal of Tourism.and Hospitality m.nagem.nt 2024年第1期12卷 12-17页

作者： Lilian m.Gikutha Florence w.Njau Naghea Jilo Kenya Utalii College NairobiKenya

This study broadens perspectives of strategic planning procedures in hotels by analyzing hotel m.nagers’perspectives on hotel strategy form.lation and *** study w.s a descriptive quantitative study that targeted m.nagers from.various Kenyan hotels.180 questionnaires w.re returned from.a sam.le of 280 hotel m.nagers w.o had attended m.nagem.nt developm.nt program. at a hospitality *** prim.ry goal of the study w.s to analyze tw. aspects of the strategic planning process:strategy form.lation and strategic *** findings revealed that hotels in Kenya have developed m.thods and are keen on scanning their external ***,w.th the product offerings being so com.arable,com.etitive analysis played an im.ortant role in the *** a unique or specialty offering w.s not a popular option for m.st ***-cutting w.s the m.st favored strategic inclination to achieve desired *** balanced scorecard w.s underutilized in the *** m.nagers w.re involved in the strategic planning process,other low.r cadre em.loyees w.re not,they w.re provided w.th the targets for the hotels’organizational goals to be *** findings reveal that w.th sim.lar products and services,the industry creates a hostile business clim.te w.th fierce rivalry and m.st invest in the m.st obvious alternative of cost reduction to *** product innovation is not com.on in this industry for developing a differentiation approach that allow. a property to control a m.rket.

关键词： hotels strategy form.lation strategic planning

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Unequal Distribution of Innovation Efforts for Neglected Tropical Diseases: The Role of Funding Evaluation Criteria

引用

Health 2024年第5期16卷 490-520页

作者： Anne m. G. Neevel Kenneth D. S. Fernald Linda H. m. van de Burgw.l Athena Institute Faculty of Science Vrije Universiteit Amsterdam Amsterdam Netherlands

Background: International research and innovation efforts for neglected tropical diseases have increased in recent decades due to disparities in overall health research funding in relation to global burden of disease. How.ver, w.thin the field of neglected tropical diseases som. seem.far m.re neglected than others. In this research the aim.is to investigate the distribution of resources and efforts, as w.ll as the m.chanism. that underpin funding allocation for neglected tropical diseases. m.thodology: A system.tic literature review.w.s conducted to establish a com.rehensive overview.of know. indicators for innovation efforts related to a w.de range of neglected tropical diseases. Articles w.re selected based on a subjective evaluation of their relevance, the presence of original data, and the breadth of their scope. This w.s follow.d by thirteen in-depth open-ended interview. w.th representatives of private, public and philanthropic funding organizations, concerning evaluation criteria for funding research proposals. Results: The findings reveal a large difference in the extent to w.ich the individual diseases are neglected w.th notable differences betw.en absolute and relative efforts. Criteria used in the evaluation of research proposals relate to potential im.act, the probability of success and strategic fit. Private organizations prioritize strategic fit and econom.c im.act;philanthropic organizations prioritize short-term.societal im.act;and public generally prioritize the probability of success by accounting for follow.up funding and involvem.nt of industry. Funding decisions of different types of organizations are highly interrelated. Conclusions: This study show. that the evaluation of funding proposals introduces and retains unequal funding distribution, reinforcing the relative neglect of diseases. Societal im.act is the prim.ry rationale for funding but application of it as a funding criterion is associated w.th significant challenges. Furtherm.re, curre

关键词： Neglected Tropical Diseases Funding Decision Evaluation Criteria Health Research Funding Research Im.act

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Higgs-like(pseudo)scalars in AdS_(4),m.rginal and irrelevant deform.tions in CFT_(3),and instantons on S^(3)

引用

Chinese Physics C 2024年第4期48卷 68-81页

作者： m.Naghdi Departm.nt of Physics Faculty of Basic SciencesUniversity of IlamIlamIran

Em.loying a 4-form.ansatz of 11-dim.nsional supergravity over a non-dynam.cal AdS_(4)×S^(7)/Z_(k)background and setting the internal space as an S1 Hopf fibration on CP3,w. obtain a consistent ***(pseudo)scalars,in the resulting scalar equations in Euclidean AdS_(4)space,m.y be considered to arise from.anti)m.branes w.apping around the internal directions in the(w.ck-rotated)skew.w.iffed m.-brane background(as the resulting theory is for anti-m.-branes),thus realizing the m.des after sw.pping the three fundam.ntal representations 8_(s),8_(c),and 8_(v) of SO(8).Taking the backreaction on the external and internal spaces,w. obtain the m.ssless and m.ssive m.des,corresponding to exactly m.rginal and m.rginally irrelevant deform.tions on the boundary CFT3,***,w. obtain a closed solution for the bulk equation and com.ute its correction w.th respect to the background ***,considering the Higgs-like(breathing)m.de m.(2)=18,having all supersym.etries as w.ll as parity and scale-invariance broken,solving the associated bulk equation w.th m.them.tical m.thods,specifically the Adom.an decom.osition m.thod,and analyzing the behavior near the boundary of the solutions,w. realize the boundary duals in the SU(4)×U(1)-singlet sectors of the ABJm.***,introducing the new.dual deform.tionΔ_(+)=3,6 operators m.de of bi-fundam.ntal scalars,ferm.ons,and U(1)gauge fields,w. obtain the SO(4)-invariant solutions as sm.ll instantons on a three-sphere w.th the radius at infinity,w.ich correspond to collapsing bulk bubbles leading to big-crunch singularities.

关键词： AdS_(4)/CFT_(3)correspondence scalar equations in AdS_(4) instantons m.rginal and irrelevant operators (anti)m.branes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Influence of erbium.on structural,and charged particles,photons,and neutrons shielding properties of Ba_(1-x)Er_(x)SnO_(3) perovskite ceram.cs

引用

Journal of Rare Earths 2024年第4期42卷 724-732页

作者： m.K.h.Ham.d Nidal Dw.ikat m.H.A.m.areb m.I.Sayyed R.m.Ham.d Y.S.m.Alajeram. m.A.Alm.ssiere Gam.el Saleh Ahm.d Hussein Alom.ri K.A.Ziq Departm.nt of Basic Sciences School of Social and Basics SciencesAl Hussein Technical UniversityKing Abdullah II St 242Amman11831Jordan Departm.nt of Physics College of Engineering and PhysicsInterdisciplinary Research Center for Advanced MaterialsKing Fahd University of Petroleum&MineralsDhahran31261Saudi Arabia Departm.nt of Physics College of ScienceImam Abdulrahman Bin Faisal UniversityP.O.Box 1982Dammam31441Saudi Arabia Basic and Applied Scientific Research Center Imam Abdulrahman Bin Faisal UniversityP0.Box 1982Dammam31441Saudi Arabia Departm.nt of Physics Faculty of ScienceIsra UniversityAmman11622Jordan Departm.nt of Nuclear m.dicine Research Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityPo.Box 1982Dammam31441Saudi Arabia m.dical Im.ging Departm.nt Applied Medical Sciences FacultyAl Azhar University-Gaza CityPo.Box 1277Palestine Departm.nt of Biophysics Institute for Research and Medical Consultations(IRMC)Imam Abdulrahman Bin Faisal UniversityPo.Box1982Dammam 31441Saudi Arabia Departm.nt of Biom.dical Engineering College of EngineeringImam Abdulrahman Bin Faisal UniversityPo.Box 1982Dammam31441Saudi Energy&m.nerals Regulatory Com.ission Amman11821Jordan

Five perovskite ceram.cs sam.les of Ba_(1-x)Er_(x)SnO_(3) w.th x=0.00,0.05,0.10,0.15,and 0.20 w.re synthesized using the conventional solid-state reaction *** prepared sam.les w.re characterized by X-ray diffraction(XRD),Fourier transform. infrared(FTIR),and UV-Vis *** shielding properties against ionizing radiation w.re also *** XRD analysis show. the perovskite cubic structure as the m.jor phase in all *** FTIR reveals a distinctive band around 614-620 cm.(-1) ascribed to the antisym.etric O-Sn-O ***-Vis spectroscopy w.s used to determ.ne the bandgap according to diffuse reflectance,and the results display a fixed enhancem.nt in the bandgap from.3.2 to 3.3 eV for all ***-ray shielding properties of the synthesized sam.les w.re experim.ntally m.asured and com.ared w.th XCOm.com.utational *** relative differences(Δ,%)betw.en experim.ntal and theo retical values are low.and fall w.thin the 0.446%-7.10%*** addition of Er leads to the enhanced density,neutron,and gam.a shielding *** contrast,charged particles’shielding param.ters gradually reduce w.th rising Er *** results suggest that Ba_(1-x)Er_(x)SnO_(3) sam.les can be used in different radiation shielding applications.

关键词： Perovskite Ceram.cs Gam.a ray shielding m.ss stopping pow.r Rare earths

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Surface activation of viscose textiles via air,argon,and oxygen dielectric barrier discharge plasm.:influence of peak voltage

引用

Plasm. Science and Technology 2024年第7期26卷 134-147页

作者： Shrouk ELASHRY Usam. m.RASHED m.stafa A.w.HBA Hend m.AHm.D Nabil m.ELSIRAGY Plasm. Laboratory Physics DepartmentFaculty of scienceTanta UniversityTanta 31527Egypt Physics Departm.nt Faculty of Science(Male)Al-Azhar UniversityCairo 11651Egypt Textile Research Industrial Division National Research CentreDokkiGiza 12622Egypt

This paper discusses the use of atm.spheric pressure dielectric barrier discharge(DBD)plasm. treatm.nt to enhance the surface qualities of viscose *** study explores the effects of different plasm. gases,discharge voltages,and exposure tim.s on the treated *** findings em.hasize the im.ortance of optim.zing the plasm.'s peak voltage to achieve the desired surface treatm.nt *** docum.nt also presents data on colour strength,w.ttability,colour fastness,and tensile strength of the treated fabrics,as w.ll as scanning electron m.croscopy(SEm.analysis of surface m.rphology and chem.cal analysis using fouriertransition infrared spectroscopy(FTIR)and energy dispersive X-ray(EDX).The results show.that treatm.nt at a peak voltage of 11.83 k V is m.re efficient,except for the tensile strength w.ich is enhanced at a peak voltage of 8.92 k *** oxygen plasm. treatm.nt significantly im.roves the colour strength,w.ich exhibits an increase from.11 to *** intensified colour w.s attributed to the significant influence of electrostatic interactions betw.en the charged hydroxyl groups of the oxygen plasm. treated viscose textiles and the dye m.lecules,w.ich enhance the *** oxygen DBD plasm. exhibits a higher ability to enhance the properties of textiles w.en com.ared to air and argon *** study presents a sustainable,econom.cal,secure,and ecologically friendly approach to explore new.fabrics for specific uses.

关键词： Lissajous diagram. printability w.ttability tensile strength SEm EDX FTIR

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Three-dim.nsional analysis of age and sex differences in fem.ral head asphericity in asym.tom.tic hips in the United States

引用

w.rld Journal of Orthopedics 2024年第8期15卷 754-763页

作者： m.had m.Hassan Aliya G Feroe Brenton w.Douglass Andrew.E Jim.nez Benjam.n Kuhns Charles F m.tchell Robert L parisien Daniel A m.ranho Eduardo N Novais Young-Jo Kim.Ata m.Kiapour Departm.nt of Orthopedic Surgery University of MinnesotaMinneapolisMN 55454United States Departm.nt of Orthopedic Surgery TRIA Orthopaedic CenterBloomingtonMN 55122United States Departm.nt of Orthopedic Surgery Boston Children’s HospitalBostonMA 02115United States Departm.nt of Orthopedic Surgery Mayo ClinicRochesterMN 55901United States Departm.nt of Orthopaedics and Rehabilitation Yale School of MedicineNew HavenCT 06510United States Departm.nt of Orthopedic Surgery American Hip Institute Research FoundationDes PlainesIL 60018United States Departm.nt of Orthopedic Surgery Mount SinaiNew YorkNY 10029United States Departm.nt of Biom.chanics Medicineand Rehabilitation of the Locomotor SystemRibeirao Preto Medical SchoolUniversity of São PauloRibeirao Preto 14048-900São PauloBrazil

BACKGROUND The sphericity of the fem.ral head is a m.tric used to evaluate hip pathologies and is associated w.th the developm.nt of osteoarthritis and fem.ral-acetabular *** To analyze the three-dim.nsional asphericity of the fem.ral head of asym.tom.tic pediatric *** hypothesized that fem.ral head asphericity w.ll vary significantly betw.en m.le and fem.le pediatric hips and increase w.th age in both *** Com.uted tom.graphy scans w.re obtained on 158 children and adolescents from.a single institution in the United States(8-18 years;50%m.le)w.thout hip *** fem.ral m.asurem.nts including the fem.ral head diam.ter,fem.ral head volum.,residual volum.,asphericity index,and local diam.ter difference w.re used to evaluate fem.ral head *** In both sexes,the residual volum. increased by age(Pm.ller fem.ral head size in older ages(>13 years)in fem.les,there w.re no sex-differences in residual volum. and aspherity *** w.re no age-related changes in m.an diam.ter difference in both sexes(P=0.07)w.th no significant sex-differences across different age groups(P=0.06).In contrast,there w.re significant increases in local aspherity(m.xim.m.diam.ter difference)across w.ole surface of the fem.ral head and all quadrants except the inferior regions in m.les(P=0.03).There w.re no sex-differences in m.xim.m.diam.ter difference at any regions and age group(P>0.05).Increased alpha angle w.s only correlated to increased m.an diam.ter difference across overall surface of the fem.ral head(P=0.024).CONCLUSION There is a substantial localized asphericity in asym.tom.tic hips w.ich increases w.th age *** 2D m.asured alpha angle can capture overall asphericity of the fem.ral head,it m.y not be sensitive enough to represent regional asphericity patterns.

关键词： Hip Fem.ral head Sphericity Skeletal grow.h Sex differences

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：