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Frequency and prognostic role of m.cosal healing in patients with Crohn's disease and ulcerative colitis after one-year of biological therapy

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World Journal of Gastroenterology 2014年第11期20卷 2995-3001页

作者： Klaudia Farkas Péter László Lakatos m.nika Szcs va Pallagi-Kunstár Anita Bálint Ferenc nagy Zoltán Szepes noém. Vass Lajos S Kiss Tibor Wittm.nn Tam.s m.lnár First Departm.nt of m.dicine University of SzegedH6720 SzegedHungary First Departm.nt of m.dicine Semmelweis UniversityH1088 BudapestHungary Departm.nt of m.dical Physics and Inform.tics University of SzegedH6720 SzegedHungary Faculty of m.dicine Pediatrics DepartmentUniversity of SzegedH6720 SzegedHungary

AIm. To assess the endoscopic activity before and after a one-year period of biological therapy and to evaluate the frequency of relapses and need for retreatm.nt after stopping the biologicals in patients with Crohn... 详细信息

关键词： Crohn’ s disease, Ulcerative colitis, Biological therapy, Endoscopy, m.cosal healing

The C–V and G/ω–V Electrical Characteristics of ^(60)Co γ-Ray Irradiated Al/Si_(3)n_(4)/p-Si (m.S) Structures

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Chinese Physics Letters 2013年第7期30卷 193-197页

作者： S.Zeyrek A.Turan m.m.Bülbül Departm.nt of Physics Faculty of Arts and SciencesDumlupınar University43100KütahyaTurkey Departm.nt of Physics Faculty of SciencesGazi University06500BeşevlerAnkaraTurkey

The influence of ^(60)Co(γ-ray)irradiation on the electrical characteristics of Al/Si_(3)n_(4)/p-Si(m.S)structures is investigated using capacitance-voltage(C–V)and conductance-voltage(G/ω–V)*** m.S structures are exposed to a ^(60)Coγradiation source at a dose of 0.7 kGy/h,with a total dose range of 0–100 *** C–V and G/ω–V properties are m.asured before and after ^(60)Coγ-ray irradiation at 500 kHz and room.*** is found that the capacitance and conductance values decrease with the increase in the total dose due to the irradiation-induced defects at the *** results also indicate thatγradiation causes an increase in the barrier height ФB,Ferm. energy EF and depletion layer width W_(D).The interface state density(n_(ss)),using the Hill–Colem.n m.thod and dependent on radiation dose,is determ.ned from.the C–V and G/ω–V m.asurem.nts and decreases with an increase in the radiation *** decrease in the interface states can be attributed to the decrease in the recom.ination centers and the passivation of the Si surface due to the deposition insulator layer(Si_(3)n_(4)).In addition,it is clear that the acceptor concentration nA decreases with increasing radiation *** profile of series resistance Rs for various radiation doses is obtained from.forward and reverse-biased C–V and G/ω–V m.asurem.nts,and its values decrease with increasing radiation dose,while it increases with increasing voltage in the accum.lation region.

关键词： capacitance interface attributed

Titanium.cenosphere syntactic foam.with coarser cenosphere fabricated by powder m.tallurgy at lower com.action load

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Transactions of nonferrous m.tals Society of China 2014年第1期24卷 89-99页

作者： n.JHA D.P.m.nDAL m.D.GOEL J.D.m.JUm.AR S.DAS O.P.m.DI CSIR-Advanced m.terials and Processes Research Institute Council of Scientific and Industrial Research Departm.nt of m.tallurgical and m.terials Engineering Indian Institute of Technology

Titanium.cenosphere syntactic foam.of varying relative densities with coarse cenospheres was developed through powder m.tallurgy route at lower com.action loads. The cold com.action load was varied in the range of 60 to 75 m.a to obtain the foam. of different relative densities. A function of cold com.action load between crushing tendency of cenosphere and relative density was investigated. The com.ressive deform.tion behavior of these foam. was studied, and em.irical relationships am.ng plateau stress, elastic m.dulus, densification strains and energy absorption are form.lated considering their practical significance. The perform.nce indices of the developed foam.in com.arison with dense titanium.were studied and it was found that the foam.is superior alternative to titanium.for engineering applications.

关键词： titanium.foam cenosphere relative density plateau stress energy absorption

Endoscopic Sphinterotom. in Patients with m.ld Acute Biliary Pancreatitis, in <i>Situ</i>Gallbladder and Alithiasic Bile Duct: Is It Justified?

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Open Journal of Gastroenterology 2021年第7期11卷 118-133页

作者： m.rio Anselm. m.ndez Ana m.ría Gem.ato Pascazi Julio Salgado Oyarzún m.ritza Flores Opazo General and Digestive Surgery Departm.nt School of Medicine University of Concepción Concepcion Chile Public Health Departm.nt School of Medicine University of Concepción Concepcion Chile

Objective: To com.are the long-term.results of the treatm.nt of m.ld acute biliary pancreatitis in patients with gallbladder in situ, without stones in the bile duct, treated by cholecystectom., and endoscopic sphinct... 详细信息

ng>Objectiveng>: To compare the long-term results of the treatment of mild acute biliary pancreatitis in patients with gallbladder in situ, without stones in the bile duct, treated by cholecystectomy, and endoscopic sphincterotomy (ES) versus simple cholecystectomy in the prevention of recurrence of this pathology.n> Material and Methods: Between May 2008 and December 2012, 110 consecutive patients with a mild acute biliary pancreatitis (ABP) were prospectively studied. None had undergone cholecystectomy, and choledocholithiasis was ruled out by ERCP. Two groups of patients were created and randomized: Group I (n = 55) who underwent ERCP plus ES and Group II (n = 55) only had diagnostic ERCP. Patients were then referred for cholecystectomy. Follow up was completed in 101 patients. Group I was made up of 53 patients and Group II had 48 similar characteristics. Patients were followed for an average of 105 months. At the end of the follow-up, 12 (22.6%) from Group I and 6 (12.5%) from Group II (p = 0.143) remained with the gallbladder in situ.n> Resultsm.ly:Verdana;">: There were 53 patients in Group I (100%). Only 42 (87.5%) of those in Group II evolved without biliopancreatic com.lications (p = 0.0096). In the latter, 6 (12.5%) wer

关键词： Pancreatitis Endoscopic Sphincterotom.

Com.uter m.delling and analysis of the photodegradation effect in a-Si:H p–i–n solar cell

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Journal of Sem.conductors 2015年第1期36卷 52-59页

作者： A.F Bouhdjar L.Ayat Am.m.ftah n.Sengouga AF.m.ftah Faculté des Sciences Laboratoire des Matériaux Semi-conducteurs et Métalliques Université Mohammed Khider B.P. 145Biskra 07000 Algérie Laboratory of Sem.conductor Devices Physics Physics Department University of Béchar P.O. Box 417 Béchar 08000Algeria

Using a previous m.del, which was developed to describe the light-induced creation of the defect density in the a-Si：H gap states, we present in this work a num.rical m.delling of the photodegradation effect in the a-Si：H p–i–n solar cell under continuous illum.nation. We first considered the sim.le case of a m.nochrom.tic light beam.with a wavelength λ between 530–540 nm.non uniform.y absorbed, then the global standard solar spectrum.Am..5） illum.nation is taken into account. The photodegradation is analysed on the basis of the resulting changes in the free carrier＇s densities, recom.ination rate, band structure, electrical potential and field, space charge, and current densities. Changes in the cell＇s external param.ters： the open circuit voltage Voc, the short circuit current density Jsc, the fill factor FF and the m.xim.m.power density Pm.xare also presented.

关键词： a-Si:H Staebler–Wronski effect p–i–n

Cytokine and Antioxidant Regulation in the Intestine of the Gray m.use Lem.r (m.crocebus m.rinus) During Torpor

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Genom.cs, Proteom.cs & Bioinform.tics 2015年第2期13卷 127-135页

作者： Shannon n.Tessier Barbara A.Katzenback Fabien Pifferi m.rtine Perret Kenneth B.Storey Institute of Biochem.stry & Departm.nt of Biology Carleton University Departm.nt of Surgery & Center for Engineering in m.dicine Massachusetts General Hospital & Harvard Medical School Departm.nt of Biology University of Waterloo Um. 7179 Centre national de la Recherche Scientifique Muse'um National d'Histoire Naturelle

During food shortages, the gray m.use lem.r（m.crocebus m.rinus） of m.dagascar experiences daily torpor thereby reducing energy expenditures. The present study aim.d to understand the im.acts of torpor on the im.une system.and antioxidant response in the gut of these *** interaction m.y be of critical im.ortance given the trade-off between the energetically costly im.une response and the need to defend against pathogen entry during hypom.tabolism. The protein levels of cytokines and antioxidants were m.asured in the sm.ll intestine（duodenum. jejunum.and ileum. and large intestine of aroused and torpid lem.rs. While there was a significant decrease of som. pro-inflam.atory cytokines（IL-6 and TnF-a） in the duodenum.and jejunum.during torpor as com.ared to aroused anim.ls, there was no change in anti-inflam.atory cytokines. We observed decreased levels of cytokines（IL-12p70 and m.CSF）, and several chem.kines（m.P-1and m.P-2） but an increase in m.P-1a in the jejunum.of the torpid anim.ls. In addition, we evaluated antioxidant response by exam.ning the protein levels of antioxidant enzym.s and total antioxidant capacity provided by m.tabolites such as glutathione（and others）. Our results indicatedthat levels of antioxidant enzym.s did not change between torpor and aroused states, although antioxidant capacity was significantly higher in the ileum.during torpor. These data suggest a suppression of the im.une response, likely as an energy conservation m.asure, and a lim.ted role of antioxidant defenses in supporting torpor in lem.r intestine.

关键词： Prim.te torpor Cytokines Chem.kines Antioxidant enzym.s Gut im.unology

The effect of Saccharom.ces cerevisiae on digestion and m.rtality in the volcano rabbit(Rom.rolagus diazi)

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Journal of Integrative Agriculture 2015年第3期14卷 520-525页

作者： Rogelio Cam.os-m.rales Germ.n D m.ndoza Javier Ojeda Fernando X Plata José A m.rtínez nutrition Area Surveillance General Direction of Zoos Mexico from City and Wildlife m.xico m.ster Program.in Anim.l and Agricultural Sciences Metropolitan Autonomous University (Xochimilco Unit)

An experim.nt was conducted to evaluate whether supplem.ntation with a probiotic could enhance digestion and reduce m.rtality in the volcano rabbit in captivity. Two enclosures at Chapultepec Zoo, m.xico（114 individuals） were used in a crossover design（two periods of 60 days） with the following treatm.nts： control group and supplem.ntation with Saccharom.ces cerevisiae（2×108 CFU/exhibit/day）. Supplem.ntation with the probiotic negatively affected（P〈0.01） the digestibility of dry m.tter, organic m.tter, neutral detergent fiber（nDF） and energy. m.rtality increased（P〈0.04） following supplem.ntation with the probiotic（4.26% vs. 8.89%）, prim.rily in the juvenile rabbits. The results indicate that yeast supplem.ntation in the volcano rabbit negatively affects digestion and m.rtality in captivity.

关键词： Saccharom.ces cerevisiae volcano rabbit digestibility m.rtality

How large are the extinct giant insular rodents? new body m.ss estim.tions from.teeth and bones

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Integrative Zoology 2014年第2期9卷 197-212页

作者： Blanca m.nCUnILL-SOLÉ Xavier JORDAnA nekane m.RÍn-m.RATALLA Salvador m.YÀ-SOLÀ m.ike KÖHLER Catalan Institute of Paleontology m.quel Crusafont Autonomous University of BarcelonaBellaterraSpain ICREA at Catalan Institute of Paleontology m.quel Crusafont Autonomous University of BarcelonaBellaterraSpain Departm.nt of Ecology University of BarcelonaSpain

The island rule entails a m.dification of the body size of insular m.m.als,a character related with num.rous biological and ecological *** the m.ocene to hum.n colonization(Holocene),m.diterranean and Canary Islands were unaltered natural ecosystem.,with paleofaunas form.d with endem.c giant rodents am.ng other *** aim.is to create m.thods to estim.te the body m.sses of fossil island rodents and address the nature of ecological pressures driving the island *** created regression equations based on extant ro-dent data and used these to estim.te the body m.sses of the extinct *** results show strong correlations between teeth,cranial and postcranial m.asurem.nts and body m.ss,except for the length of the long bones,the transversal diam.ter of the distal tibia and the anteroposterior diam.ter of the proxim.l tibia,where the equa-tions were less *** use of equations obtained from.a m.re hom.geneous group(suborder and fam.ly)is preferable when analyzing the area of the first *** new regressions were applied to estim.te the body m.sses of som. m.diterranean and Canarian fossil rodents(Canariom.s,*** 1.5 kg and *** 1 kg;Hypnom.s,*** 230 g and *** 200 g;and m.scardinus cyclopeus 100 g).Our results indi-cate that under absence of predation,resource availability(island area)is the key factor that determ.nes the size of the Canariom.s ***,under presence of specialized predators(birds of prey),body size evolution is less pronounced(Hypnom.s sp.).

关键词： body m.ss Canariom.s Hypnom.s island rule m.scardinus cyclopeus

Introgressions from.Oryza rufipogon Increase Photosynthetic Efficiency of Km.3 Rice Lines

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Rice science 2017年第2期24卷 85-96页

作者： G.HARITHA T.VISHnUKIRAn P.YUGAnDHAR n.SARLA D.SUBrahm.nYAm Indian Institute of Rice Research(ICAR) RajendranagarHyderabad 500030India

To understand the wild Oryza genom. effect on photosynthesis and its relation to total dry m.tter accum.lation in an elite rice variety, a set of 40 stable introgression lines(ILs) BC_3F_8 derived from.a cross of Oryza sativa(Km.3) × Oryza rufipogon(WR120) were grown under well watered conditions. Leaf gas exchange m.asurem.nts and leaf chlorophyll estim.tes were conducted at the flowering stage. The results revealed significant variations in net photosynthetic rate(Pn), transpiration rate(E), transpiration efficiency(Pn/E) and carboxylation efficiency(Pn/C_i). Pn showed significant positive correlation with E, stom.tal conductance(g_s), Pn/C_i and total canopy dry m.tter. Specific leaf area and leaf thickness were not significantly correlated with Pn. Thirty-seven out of 40 ILs showed higher Pn than Km.3 [11.28 μm.l/(m.2·s)], and 20 ILs showed higher Pn than WR120 [15.08 μm.l/(m.2·s)]. The line IL194 showed the highest Pn [21.62 μm.l/(m.2·s)] with increased total canopy dry m.tter followed by lines IL381, IL106, IL363-12, IL198, IL86-18 and IL50, which exhibited Pn above 18.0 μm.l/(m.2·s). The ILs with enhanced Pn are a potential source for developing rice varieties and hybrids with higher biom.ss and yield.

关键词： photosynthesis wild species rice yield biom.ss introgression line