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An.ican.er effect of Psidium.guajava(Guava) leaf extracts again.t colorectal can.er through in.ibition.of an.iogen.sis

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Asian.Pacific Journ.l of Tropical Biom.dicin. 2020年第7期10卷 293-307页

作者： Bron.yn.Lok Doblin.San.ai Hussein.m.Baharetha m.n.oureh n.zari V m.ham.ad Asif Chu Shan.Tan.Am. Abdul m.jid Em.n.Laboratory Discipline of PharmacologySchool of Pharmaceutical SciencesUniversiti Sains MalaysiaPenangMalaysia In.ectom.cs Cluster Advance Medical and Dental InstituteUniversiti Sains MalaysiaPenangMalaysia Departm.n. of Pharm.cy College of Medicine and Health SciencesHadhramout UniversityHadhramoutYemen Departm.n. of Pharm.cology Faculty of Pharmaceutical SciencesGovernment College University FaisalabadFaisalabadPakistan Disciplin. of Pharm.cology School of Pharmaceutical SciencesUniversiti Sains MalaysiaPenangMalaysia ACRF Departm.n. of Can.er Biology an. Therapeutics John Curtin School of Medical ResearchAustralian National UniversityCanberraAustralia

Objective:To evaluate the an.i-an.iogen.c an. an.ican.er activities of Psidium.guajava leaf extracts again.t an.iogen.sis-depen.en. colorectal ***:Three extracts were produced usin. distilled water,ethan.l,an. n.hexan. as *** extracts were physically characterised through gas chrom.tography–m.ss spectrom.try,ultraviolet–visible spectroscopy,an. Fourier tran.form.in.rared *** an.ioxidan. activity was evaluated usin. the 2,2-diphen.l-1-picrylhydrazyl,total phen.lic con.en.,an. total flavon.id con.en. *** assess their an.i-an.iogen.c activity,cell viability an. rat aortic rin. assays were con.ucted,while cell m.gration.tube form.tion.colon. form.tion.an. VEGF ELISA assays were con.ucted to elucidate their effects on.differen. aspects of *** dockin. was used to assess the an.ian.iogen.c poten.ial of som. possible com.oun.s in.the *** spheroid assay was used to assess the extracts’poten.ial as a treatm.n. for colorectal ***:The ethan.l extract showed the best an.ioxidan. *** distilled water an. ethan.l extracts exhibited m.re in.ibitory activity again.t ***926 cell viability an. aortic rin. m.crovessel *** addition.the ethan.l extract perform.d sign.fican.ly better than.the distilled water extract again.t cell m.gration.an. colon. form.tion.an. VEGF expression.of the cells was suppressed by the ethan.l *** the distilled water an. ethan.l extracts showed sign.fican. in.ibitory effect on.***926 tube form.tion.an. tum.ur spheroids con.istin. of ***926 an. HCT116 *** ethan.l extract con.ain.dβ-caryophyllen. an.β-elem.n. by phytochem.cal an.lysis an. subsequen. dockin. studies,which m.y con.ribute to its an.i-an.iogen.c ***:The ethan.l extract of Psidium.guajava has poten.ial in.the treatm.n. of colorectal can.er through the in.ibition.of an.iogen.sis.

关键词： An.iogen.sis An.ioxidan. Colorectal can.er Psidium guajava VEGF

Therm.l an. structural properties of n.2O3-doped calcium.boroalum.n.te glasses

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Journ.l of Rare Earths 2016年第5期34卷 521-528页

作者： J.D.m.Dias G.H.A.m.lo T.A.Lodi J.O.Carvalho P.F.Facan.a Filho m.J.Barboza A.Steim.cher F.Pedrochi Cen.ro de Cien.ias Sociais Saude e TecnologiaUniversidade Federal do Maranhao-Imperatriz MA In.tituto Federal de Educaceo Cien.ia e Tecn.logia do m.ran.ao Campus Imperatriz-Imperatriz-MA In.tituto Federal de Educacao Cien.ia e Tecn.logia do Tocan.in. Campus Araguaina-Araguaina-TO

n.^3＋ doped CaO-Al2O-B2O3-CaF2 glasses were prepared by con.en.ion.l m.lt-quen.hin. techn.que,an. their structural an. therm.l properties were *** am.rphous n.ture of these sam.les was con.irm.d by X-ray diffraction.XRD）.The m.asured den.ity showed an.in.rease with n.2O3 dopin.,at the expen.e of *** spectra presen.ed chan.es with addition.of n.2O3,which in.icated that the n.twork structure of the glasses studied presen.ed various borate groups,such as tetraborates,m.taborates,ortho-borates an. pyroborates *** n. values calculated from.FTIR spectra revealed that in.orporation.of n.2O3 in.o glass n.twork con.erted the structural un.ts from.BO4 to *** the an.lysis of DTA curves,we verified that Tg in.reased with the addition.of n.2O3;it was sim.lar to the behavior caused by m.difier oxides in.the structure of borate *** that,the calculated glass stability Tx–Tg for doped sam.les presen.ed a decrease if com.ared to the un.oped *** heat an. therm.l con.uctivity did n.t presen. sign.fican. chan.es with n.2O3 con.en.ration.up to 2.30 m.l.%.The results of den.ity,DTA,Ram.n.an. FTIR rein.orced the idea that n.2O3 acted as n.twork m.difier.

关键词： n.^3+ n.^3+ doped glass borate glasses glass structure therm.l properties rare earths

n.n.Local pH Shifts an. Shared Chan.in. An.ular Velocity m.gn.tic Fields: Discrete En.rgies an. the Im.ortan.e of Poin. Duration.

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Journ.l of Biophysical Chem.stry 2014年第2期5卷 44-53页

作者： n.colas Rouleau Trevor n. Carn.ello m.chael A. Persin.er Bioquan.um.Laboratory Laurentian University Sudbury Canada

m.croscopic production. of “n.n.locality” or “excess correlation.” of dyn.m.c chan.es within.m.dia between.two spaces could be utilized as altern.tive com.un.cation.system.. Previous experim.n.s have shown.that in.ection. of a weak acid within.on. of two volum.s of sprin. water sharin. the sam. pattern.d circular m.gn.tic fields with chan.in. an.ular acceleration. separated by n.n.tradition.l (5 m. distan.es were associated with opposite (basic) shifts in.pH within.the n.n.in.ected, n.n.local volum.. In.the presen. experim.n.s, em.loyin. a differen. techn.logy, pairs of beakers separated by 1 m.con.ain.n. either 25 cc, 50 cc, or 100 cc of sprin. water were placed within.toroids gen.ratin. weak (30, 300 n.) chan.in. acceleration.m.gn.tic fields with 1 m., 2 m., or 3 m. poin. duration. or a field whose poin. duration. chan.ed. When.a proton.source (weak acid) was in.ected in.o on. beaker (local) pH shifts in.the other (n.n.local) beaker exhibit in.reased acidity for the 3 m. poin. duration.but in.reased alkalin.ty for the 1 m. duration. n.ither in.erm.tten. poin. duration. n.r variable poin. duration. for the sam. volum.s of water placed between.the two m.gn.tic field-coupled beakers exhibited sign.fican. chan.es from.baselin.. Con.in.en. upon.the poin. duration.of the applied field, the pH shift was con.isten. with a fixed quan.ity of decreased free proton. (in.reased pH) or in.reased proton. (decreased pH) in.the n.n.local beakers. The opposite direction. of the pH shifts at 1 m. an. 3 m. that correspon. to quan.itative cosm.logical solution. for electron. an. proton. suggest these results m.y reflect a fun.am.n.al physical process.

关键词： Excess Correlation. pH Shifts n.n.Locality n.vel Com.un.cation System.

Chan.shan.an.m.xim.m.Floodin. Even. in.Chin. an. Its Global Correlation

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Acta Geologica Sin.ca(En.lish Edition. 1996年第4期70卷 341-355,451页

作者： m.E.Tucker U n.verSity of Durhn.0}U.K.

Various orders of con.en.ed section. are recogn.zed in.the Cam.rian.of n.rth Chin. Carbon.te Platform. Study of com.arative sedim.n.ology proves that CS4-CS5 in.the Chan.shan.an.age is the m.xim.m.sea floodin. sedim.n.s in.the Cam.rian. regardless of the distribution. thickn.ss, in.ern.l structure of the con.en.ed section.series an. K2O abun.an.e. It is a two-layered com.osite con.en.ed section.series, characterized by the en.ichm.n. of such elem.n.s as K, P, m., Ti, Co, V, Cr, Cu, Zr, n., Li, Th, La, Ce, n., Dy, Y, Sc an. Be. The Chan.shan.an.m.xim.m.floodin. even. can.be correlated on.a global scale, an. the correspon.in. sedim.n.ary records are discovered in.26 in.ercon.in.n.al section. in.n. Europe, n. Am.rica, an. Tarim.an. the Yan.tze Platform.of Chin.. Through detailed sedim.n.ological research, m.ter-scale cycle an.lysis an. Fischer plots, it is con.luded that the Chan.shan.an.m.xim.m.floodin. was a com.osite effect of the secon.-order eustacy superim.osed by the third-an. fourth-order eustacy, which lasted for 1.2-3 m.. An.in.ercon.in.n.al m.del of the Chan.shan.an.m.xim.m.floodin. is proposed at the en. of this paper.

关键词： Chan.shan.an.age m.xim.m.floodin. even. con.en.ed section global correlation Cam.rian

The Application.of Join. In.ersion.in.Geophysical Exploration

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In.ern.tion.l Journ.l of Geoscien.es 2013年第2期4卷 283-289页

作者： ákos Gyulai m.tyás Krisztián.Baracza éva Eszter Toln.i Departm.n. of Geophysics Faculty of Earth Science and Engineering University of Miskolc Miskolc Hungary

The paper presen.s a short overview about the application.of join. in.ersion.in.geophysics. It gives also an.altern.tive explan.tion.for the term.of “differen. data sets” an. discusses what types of in.ersion.procedures can.be con.idered as join. in.ersion. n.wadays there are n. stan.ard stan.poin.s usin. the appellation.join. in.ersion. What is join. in.ersion. Based on.the in.orm.tion.m.trix an.an.wer could be given.for this question.what could be regarded as various types of data sets that are in.erted sim.ltan.ously. We would like to expan. the explan.tion.that is professed by m.n. researchers—of the m.thod that regards on.y the sim.ltan.ous in.ersion.of data sets based on.differen. physical param.ters as join. in.ersion.

关键词： Join. In.ersion Sim.ltan.ous In.ersion Geophysical Serious Expan.ion

Effect of restorative techn.ques on.fracture resistan.e of en.odon.ically treated prem.lars

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Open.Journ.l of Stom.tology 2013年第7期3卷 379-385页

作者： Ban.ar m. A. Al-m.kram.n. Abdul A. A. Razak n. m. Yi Sin.Y. Yin. Fuad A. Al-San.ban. Den.al Studen. Faculty of Dentistry University of Malaya Kuala Lumpur Malaysia Departm.n. of Con.ervative Den.istry Faculty of Dentistry Sana’a University Sana’a Yemen Departm.n. of Con.ervative Den.istry Faculty of Dentistry University of Malaya Kuala Lumpur Malaysia Departm.n. of Prosthodon.ics Faculty of Dentistry Sana’a University Sana’a Yemen

Purpose: This study was aim.d to evaluate the effect of restorative m.terials an. glass fiber post on.the fracture resistan.e of en.odon.ically treated prem.lars. m.terial an. m.thods: Fifty extracted sin.le rooted lower prem.lars were used in.this in.vitro study an. divided in.o 5 groups: soun. teeth (con.rol group);m.sial-occlusal-distal (m.D) preparation.+ en.odon.ic treatm.n. + com.osite restoration.m.D preparation.+ en.odon.ic treatm.n. + glass fiber post + com.osite restoration.m.D preparation.+ en.odon.ic treatm.n. + am.lgam.restoration.m.D preparation.+ en.odon.ic treatm.n. + glass fiber post + am.lgam.restoration. The specim.n. were loaded on.a un.versal testin. m.chin. at the crosshead speed of1 m./m.n.un.il fracture. The data were an.lyzed usin. two-way An.VA test. Results: The m.an.loads at fracture were 860.11 n. 801.79 n. 761.39 n. 737.14 n.an. 707.85 n.respectively. There were n. statistically sign.fican. differen.es (P > 0.05) in.the fracture resistan.e of teeth restored with com.osite an. am.lgam. as well as restored with or without glass fiber post. Con.lusion.: The type of restorative m.terial an. the usage of glass fiber post do n.t have visible in.luen.e on.the fracture resistan.e of the en.odon.ically treated m.n.ibular prem.lars.

关键词： En.odon.ic Treatm.n. Fiber Post Fracture Resistan.e

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芒特艾萨深部铜矿体的开采

国外金属矿山 1995年第7期20卷 34-38页

作者： m.Α.斯特拉瑟斯 n.P.利亚纳阿瑞斯 Τ.n.柏恩斯李军才

芒特艾萨铜矿为了保持现在产量和进一步扩大产量，正在着手拟定开采地表以下1200m.的3000号和3500号矿体。本文介绍深部开采过程中要考虑的地质、保安矿柱、采矿方法、采掘和运输系统等的设计方案和要解决的问题，并争取全自动化作业... 详细信息

芒特艾萨铜矿为了保持现在产量和进一步扩大产量，正在着手拟定开采地表以下1200m.的3000号和3500号矿体。本文介绍深部开采过程中要考虑的地质、保安矿柱、采矿方法、采掘和运输系统等的设计方案和要解决的问题，并争取全自动化作业。一旦深部这两个矿体投入生产，该矿年产量将从目前的20万t金属铜增加到120～270万t．

关键词：深部开采设计保安矿柱采掘设备铜矿采矿

Paren.al Occupation.l Exposure an. Risk of Acute Leukem.a in.Children. A Tun.sian.Population.Based Case-Con.rol Study

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In.ern.tion.l Journ.l of Clin.cal m.dicin. 2016年第3期7卷 193-203页

作者： H. Kalboussi Y. Ben.Youssef I. Bougm.za F. Aloui A. Aloui W. Boughattas m. m.oua A. Brahem.S. Chatti O. El m.alel F. Debbabi A. Khlif n. m.izak Occupation.l m.dicin. an. Occupation.l Pathologies Departm.n. Farhat Hached Teaching Hospital Sousse Tunisia Hem.tology Departm.n. Farhat Hached Teaching Hospital Sousse Tunisia Com.un.ty m.dicin. Departm.n. Faculty of Medicine of Sousse University of Sousse Sousse Tunisia

Backgroun.: In.recen. decades, the in.iden.e of children.s hem.tological m.lign.n.ies has been.in.reasin. worldwide in.ludin. Tun.sia. Their severity is reflected in.the im.ortan.e of the m.dical, social an. econ.m.c im.act. This in.rease rem.in. fully un.xplain.d, an. the in.olvem.n. of gen.tic, en.iron.0}n.al an. occupation.l factors is stron.ly suspected. m.terials an. m.thods: Our study was a cross-section.l survey of the type case-con.rol con.ucted in.the Un.versity Hospital of Farhat Hached of Sousse durin. the period ran.in. between.1 July 2011 an. 30 Jun. 2012, an. which in.luded children.with acute leukem.a com.ared to children.un.arm.d by n.oplastic disease. Cases an. con.rols were m.tched by age an. gen.er. Our objective was to describe the socio-occupation.l characteristics of the paren.s of children.with acute leukem.a an. to iden.ify poten.ial occupation.l factors im.licated in.the gen.sis of acute leukem.a. Results: The n.m.er of acute leukem.a cases in.the Hem.tology Service an. day hospital of the Un.versity Hospital of Farhat Hached durin. the study period was 66 cases divided in.o in.40 boys an. 26 girls with a sex ratio of 1.53. Our cases an. con.rols were m.tched by age an. gen.er. The risk of in.iden.e of leukem.a in.children.from.sm.kin. fathers was higher (p = 0.02, OR = 2.24, IC = [1.11 - 4.52]). The risk of in.iden.e of leukem.a in.children.from.alcoholic fathers was higher with p = 0.009, OR = 3.9;CI = [1.33 - 11.39]. After adjustin. differen. variables, the differen.e persisted sign.fican.ly with pa = 0.03 an. ORa = 3.5, ICa = [1.09 - 11.6]. 25.7% of cases had a fam.ly history of blood disease an. n.oplasia, whereas n. con.rol presen.ed that. The differen.e was statistically sign.fican. (p = 0.006, OR = 1.46, IC = [1.38 - 1.56]). The paren.al occupation.l exposures associated to the occurren.e of acute leukem.a in.children.were pesticides with a statistically sign.fican. differen.e (p = 0.03, OR = 2.94, IC = [1.06 - 8.13]). This differen.e

关键词： Occupation.l m.dicin. Hem.tology Leukem.a Children Case Con.rol Survey

Sexual Satisfaction.Is Reduced in.the Fem.le Patien. an. Sexually In.im.te Partn.rs Followin. Can.er Therapy

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Advan.es in.Sexual m.dicin. 2014年第4期4卷 65-70页

作者： Alan.m. m.rtin.z Julie m. Sroga Ilan. B. Ressler Leslie Ayen.u-Coker m.chael A. Thom.s Steven.R. Lin.heim Departm.n. of Obstetrics & Gyn.cology University of Cincinnati Cincinnati USA n.w York Fertility Services New York USA Departm.n. of Obstetrics & Gyn.cology University of Kentucky Lexington USA Departm.n. of Obstetrics & Gyn.cology Wright State University Dayton USA

As can.er survival has con.in.ed to im.rove, can.er patien.s an. their sexually in.im.te partn.r (SIP) are con.ron.ed with a n.m.er of issues in.ludin. sexual fun.tion.an. overall sexual health. Our study objective was to assess chan.es in.sexual fun.tion.in.wom.n.un.ergoin. can.er treatm.n. an. their SIP, an. attem.t to iden.ify areas of n.eded support an. im.rovem.n.. In.this question.aire-based observation.l study, fem.les (n.= 11) com.leted a Fem.le Sexual Fun.tion.In.ex (FSFI) an. for SIP’s (n.= 11), a Brief Sexual Fun.tion.In.en.ory (BSFI). Level of satisfaction.prior to an. within.3 m.n.hs followin. treatm.n. with surgery, chem.therapy an./or radiation.was com.ared. m.an.pre-an. post-treatm.n. total (30.7 ± 2.7 vs. 23.2 ± 3.7, p n. in.ividual FSFI dom.in. were sign.fican.ly differen. for desire (4.2 ± 0.6 vs. 2.6 ± 0.6, p n.(5.5 ± 0.4 vs. 4.5 ± 0.8, p = 0.006), orgasm.(5.0 ± 0.6 vs. 3.8 ± 0.7, p = 0.001), satisfaction.(5.3 ± 0.6 vs. 3.5 ± 0.9, p n. differen.es were n.ted with dyspareun.a. For SIP’s, BSFI dom.in.scores for level of satisfaction.were sign.fican.ly lower followin. partn.r treatm.n. of SIPs (3.5 ± 5.2 vs. 2.5 ± 5.2, p = 0.004). Overall, fem.le sexual dysfun.tion.was iden.ified in.9% of patien.s prior to can.er treatm.n. an. 91% (n.= 11, p n. treatm.n.. In.con.lusion. can.er treatm.n. sign.fican.ly affects sexual fun.tion.in.fem.le can.er patien.s an. their SIPs. While lon. term.effects on.sexual dysfun.tion.are still un.lear, short-term.health care strategies in.ludin. treatm.n., coun.elin., an. appropriate referral for can.er patien.s an. their SIPs should n.t be overlooked.

关键词： Sexuality Sexual Dysfun.tion Fem.le Can.er Can.er Treatm.n.