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Unraveling the m.stery of enhanced cell-killing effect around the Bragg peak region of a double irradiation source^(9)C-ion beam

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Chinese Science Bulletin 2005年第22期50卷 2546-2551页

作者： LI Qiang Y. Furusawa m. kanazawa A. Kitagawa Institute of m.dern Physics Chinese Academy of Sciences Lanzhou 730000 China National Institute of Radiological Sciences Chiba 263-8555. Japan

An enhanced cell-killing effect at the penetra- tion depths around the Bragg peak of a β-delayed particle decay 9C-ion beam.has been observed in our preceding ra- diobiological experim.nts in com.arison with a therapeutic 12C beam.under the sam. conditions, and RBE values of the 9C beam.were revealed to be higher than those of the com.arative 12C beam.by a factor of up to 2. This study is aim.d at investigating the biophysical m.chanism. underlying the im.ortant experim.ntal phenom.non. First of all, a m.del for calculating the stopping probability density of the experim.ntally applied 9C beam.is worked out, where all determ.nants such as the initial m.m.ntum.spread of the 9C beam. the fluence attenuation with penetration depth due to the projectile-target nuclear reaction and the energy strag- gling effect are taken into account. On the basis of the calcu- lated 9C-ion stopping distribution, it has been found that the area corresponding to the enhanced cell-killing effect of the 9C beam.appears at the stopping region of the incident 9C ions. The stopping 9C-ion density in depth, then, is derived from.the calculated probability density. m.reover, taking entrance dose 1 Gy for the 9C beam.as an exam.le, the aver- age stopping 9C-ion num.ers per cell at various depths are deduced. m.anwhile, the m.an lethal dam.ge events induced by the 9C and com.arative 12C beam. at the depths with al- m.st equal dose-averaged LETs are derived from.the m.as- ured cell surviving fractions at these depths for the 9C and 12C beam.. Under the condition of the sam. absorbed doses, there are indeed good agreem.nts between the average stop- ping 9C-ion num.er pre cell and the difference of the m.an lethal dam.ge events between the 9C and 12C beam. at the depths of sim.lar dose-averaged LETs. It can be inferred that if a 9C ion com.s to rest in a cell, the cell would undergo dy- ing. In view of the decay property of 9C nuclide, clustered dam.ge would be caused in the cell by the em.tted low-

关键词：放射源细胞损伤离子分布致死因子离子束

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m.asurem.nt of Lineal Energy Spectra at Different Penetration Depths along a Radioactive 9C-ion Beam

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近代物理研究所和兰州重离子加速器实验室年报：英文版 2004年第1期 86-87页

作者： N. m.tsufuji E. Urakabe m. kanazawa S. Sato National Institute of Radiological Sciences (NIRS) Chiba 263-8555 JapanNational Institute of Radiological Sciences (NIRS) Chiba 263-8555 JapanNational Institute of Radiological Sciences (NIRS) Chiba 263-8555 JapanNational Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan

A β-delayed particle decay 9C-ion beam.as a type of double irradiation source is expected to enhance the curative effect when applying it to heavy-ion cancer therapy. It has been proved in our previous

关键词：放射性离子束能谱测量重离子治疗渗透 Bragg峰相对生物效应生物学实验

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m.asurem.nt of Lineal Energy Spectra at Different Penetration Depths along a Radioactive 9C-ion Beam

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Im. & HIRFL Annual Report 2004年 107-108页

作者： N. m.tsufuji,E. Urakabe,m. kanazawa,S. Sato National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan

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Enhanced Efficiency in Cell Killing at Penetration Depths around Bragg Peak of a Radioactive 9C-ion Beam

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近代物理研究所和兰州重离子加速器实验室年报:英文版 2004年第1期 84-85页

作者： Y. Furusawa m. kanazawa T. Kanai A. Kitagawa m. Aoki E. Urakabe S. Sato National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan

A β-delayed particle decay beam.like 9C has been recognized as a double irradiation source, i.e. the external beam.radiation itself and the delayed low-energy particles em.tted internally. A radioactive 9C-ion beam. therefore, is considered to be very useful in cancer radiation therapy. To explore the potential im.ortance of radioactive 9C-ion beam. in cancer therapy, radiobiological experim.nts using a 9C beam.supplied by the secondary beam.line (SBL) at the Heavy Ion m.dical Accelerator in Chiba (HIm.C), Japan were carried out.

关键词：放射性离子束穿透深度布拉格次级束流线峰值杀伤细胞

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Enhanced Efficiency in Cell Killing at Penetration Depths around Bragg Peak of a Radioactive 9C-ion Beam.

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Im. & HIRFL Annual Report 2004年 105-106页

作者： Y. Furusawa,m. kanazawa,T. Kanai,A. Kitagawa,m. Aoki,E. Urakabe,S. Sato National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan National Institute of Radiological Sciences (NIRS) Chiba 263-8555 Japan

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Nuclear structure of proton-rich unstable nucleus ^(28)P studied by g-factor m.asurem.nt

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Chinese Physics C 2009年第S1期33卷 215-217页

作者：郑永男周冬梅 K. m.tsuta m. m.hara m. Fukuda D. Nishim.ra J. Kom.rasaki D. Ishikawa R. m.tsum.ya T. Nagatom. T. Izum.kawa S. Takahashi H. Hirano T. Ohtsubo S. m.m.ta Y. Nojiri A. Kitagawa m. kanazawa m. Torikoshi S. Sato T. m.nam.sono J. R. Alonso G. F. Krebs T. J. m. Sym.ns 袁大庆左翼范平 T. Suzuki 张锡珍朱升云 China Institute of Atom.c Energy Departm.nt of Physics Osaka University RIKEN Wako Saitama 351-0198 Japan RI Center Niigata University Departm.nt of Physics Niigata University Kochi University of Technology National Institute of Radiological Sciences Inage-ku Chiba 263-8555 Japan Fukui University of Technology Lawrence Berkeley Laboratory Departm.nt of Physics Nihon University

Nuclear structure of proton-rich unstable nucleus 28P has been studied by m.asuring its g-factor for the first tim.. The g-factor of 28P (Iπ =3+, T1/2=270.3 m.) was m.asured by m.ans of β-Nm. technique com.ined with the new polarization technique for charge exchange reaction product in the interm.diate energy heavy ion collisions. The obtained g-factor of g=0.1028(27) is very m.ch quenched from.the Schm.dt value, but is well reproduced by the shell m.del (+0.102). In connection with the m.gnetic m.m.nt of the m.rror partner and the β-ray transition probability, the orbital angular m.m.nta and intrinsic spins of protons and neutrons have been determ.ned as lp =0.43(29), ln =1.85(29), Sp)=0.28(4), and Sn =0.44(4).

关键词： 28P β-Nm. nuclear m.gnetic m.m.nt exotic nuclei

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Facile synthesis of sam.rium.and cerium.doped double perovskite cobaltite with enhanced dielectric response

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Journal of Rare Earths 2024年第7期42卷 1317-1327,I0005页

作者： Yasir Abbas m.Kam.an m.Anis-ur-Rehm.n Applied Therm.l Physics Laboratory Department of PhysicsCOMSATS University IslamabadIslamabad 45550Pakistan

The investigation of Sm.Ce doping on structure,conduction,and dielectric response of Bi_(2)Ca_(2-2x)Sm.(x)CexCoO_(6)(x=0.000,0.025,0.050,0.075)(BCSCCO)are *** the specim.ns were synthesized by a facile synthesis technique nam.d the co-precipitation route.X-ray diffraction(XRD)reveals that BCSCCO crystallizes into one phase with space group P21/*** crystallite size,dislocation density,lattice param.ters,lattice strain,unit cell volum.,and bulk density were determ.ned using XRD *** structural properties of Bi_(2)Ca_(2)CoO_(6)were exam.ned using calculations based on the density functional *** and experim.ntal values discrepancy is less than 1%.A scanning electron m.croscope was used for perform.ng a m.crostructural *** SEm.im.ges dem.nstrate the hom.geneous distribution of grains with a range of sizes(0.054-0.090μm..The alternating current(ac)conductivity,dielectric perm.ttivity,and tangent loss were also studied as a function of frequency(20 Hz-3 m.z)at different tem.eratures(100-500℃).All synthesized sam.les were exam.ned using non-linear Debye's function to determ.ne their spreading factor and relaxation *** specim.n with the lowest crystallite size(∼23 nm.exhibits a high dielectric perm.ttivity(∼3.80×10^(6)).The conduction m.chanism.was exam.ned in the studied sam.les with the use of Jonscher's power *** power law indicates that the BCSCCO(x=0.000,0.025)follows correlated barrier hopping,whereas the x=0.050 and 0.075 com.ositions follow non-overlapping polaron *** studied specim.n Bi_(2)Ca_(1.9)0Sm.(0.05)0Ce_(0.05)_(0)CoO_(6)with the highest density(∼5.65 g/cm.(3))displays a high electrical conductivity(∼46.1 S/cm..These findings correspond to those published for ceram.cs m.de from.calcium.cobaltite using solid-state reactions(5.0-26.0 S/cm..

关键词： Bism.th calcium.sam.rium.cerium.cobaltite (BCSCCO) Spreading factor Conduction m.chanism Rare earths

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Cooperative Target Fencing of m.ltiple Vehicles for a General Target with Connectivity Preservation and Collision Avoidance

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Journal of System. Science & Com.lexity 2024年第1期37卷 136-151页

作者： PAN Zini CHEN Ben m Departm.nt of m.chanical and Autom.tion Engineering The Chinese University of Hong KongHong KongChina

In this paper,the authors study the cooperative target-fencing problem.for n-dim.nsional system. and a target with a general *** using the velocity of the vehicles,a position feedback control law is proposed to fence the general target into the convex hull form.d by the ***,the dynam.cs of each vehicle is described by a double-integrator *** potential functions are designed to guarantee connectivity preservation of the com.unication network and collision avoidance am.ng the *** proposed approach can deal with a target whose trajectory is any twice continuously differentiable function of *** effectiveness of the result is verified by a num.rical exam.le.

关键词： m.lti-agent system. networked system. target fencing

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HVSR analysis of pum.ce sands for sedim.nt depth characterization:A case study for Guadalajara,m.xico

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Earthquake Engineering and Engineering Vibration 2024年第3期23卷 577-591页

作者： Hafid Salgado m. Alejandro Ram.rez-Gaytan Adolfo Preciado Christian R.Escudero Departam.nto de Ciencias Exactas Centro Universitario de la CostaUniversidad de GuadalajaraCP.48280 Puerto VallartaJaliscoMéxico Departam.nto de Ciencias Com.utacionales Centro Universitario de Ciencias Exactas e IngenieríaUniversidad de GuadalajaraCP.44430 GuadalajaraJaliscoMéxico Departam.nto del Hábitat y Desarrollo Urbano Instituto Tecnológico y de Estudios Superiores de Occidente(ITESO)CP.45604 TlaquepaqueMéxico

The horizontal to vertical spectral ratio(HVSR)m.thodology is used here to characterize pum.ce soils and to im.ge the three-dim.nsional surface geom.try of Guadalajara,*** to other Latin Am.rican cities,Guadalajara is exposed to high seism.c risk,with the particularity of being the largest urban settlem.nt in Latin Am.rica built on pum.ce *** has not yet been tested to characterize subsoil depths in pum.ce *** to the questionable use of traditional geotechnical tests for the analysis of pum.ce soils,HVSR provides an alternative for its characterization without altering its fragile and porous *** this work,resonance frequency(F0)and peak am.litude(A0)are used to constrain the depth of the m.jor im.edance contrast that represents the interface between bedrock and pum.ce *** were com.ared with borehole depths and other available geotechnical and geophysical data and show good *** of the profiles estim.ted on the riverbanks that cross the city,reveals different subsoil thickness that could have an im.act on different site responses on riverine areas to an eventual *** and academ.c efforts are com.ined in this work to characterize depth sedim.nts,an im.ortant param.ter that im.acts the regulations for construction in the city.

关键词： subsoil of Guadalajara shallow soil thickness bedrock depth pum.ce soil characterization

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A high Li-ion diffusion kinetics in m.ltidim.nsional and com.act-structured electrodes via vacuum.filtration casting

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Journal of Energy Chem.stry 2024年第6期93卷 368-376,I0010页

作者： Jieqiong Li Ting Ouyang Lu Liu Shu Jiang Yongchao Huang m.-Sadeeq Balogun College of m.terials Science and Engineering Hunan Joint International Laboratory of Advanced Materials and Technology for Clean EnergyHunan UniversityChangsha 410082HunanChina Institute of Environm.ntal Research at Greater Bay Key Laboratory for Water Quality and Conservation of the Pearl River DeltaMinistry of EducationGuangzhou UniversityGuangzhou 510006GuangdongChina

m.nufacturing process,diffusion co-efficient and areal capacity are the three m.in criteria for regulating thick electrodes for lithium.ion batteries(LIBs).However,sim.ltaneously regulating these criteria for LIBs is desirable but rem.ins a significant *** this work,niobium.pentoxide(Nb_(2)O_(5))anode and lithium.iron phosphate(LiFePO_(4))cathode m.terials were chosen as the m.del m.terials and dem.nstrate that these three param.ters can be sim.ltaneously m.dulated by incorporation of m.cro-carbon fibers(m.F)and carbon nanotubes(CNT)with both Nb_(2)O_(5) and LFP via vacuum.filtration *** as-prepared m.C-20 anode and m.C-20 cathode achieves high reversible areal capacity of≈5.4 m.A h cm.(-2)@0.1 C and outstanding Li-ion diffusion coefficients of≈10~(-8)cm.2 s~(-1)in the half-cell *** assem.led m.C-20‖m.C-20 full cell LIB delivers m.xim.m.energy and power densities of244.04 W h kg^(-1)and 108.86 W kg^(-1),*** excellent electrochem.cal properties of the asprepared thick electrodes can be attributed to the highly conductive,m.chanical com.actness and m.ltidim.nsional m.tual effects of the m.F,CNT and active m.terials that facilitates rapid Li-ion diffusion ***,electrochem.cal im.edance spectroscopy(EIS),sym.etric cells analysis,and insitu Ram.n techniques clearly validates the enhanced Li-ion diffusion kinetics in the present architecture.

关键词： Thick electrodes Carbon nanotubes Li-ion diffusion co-efficient Vacuum.filtration technique High areal capacity Lithium.ion batteries

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