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Adaptive Fault Detection Schem. Using an Optim.zed Self-healing Ensem.le m.chine Learning Algorithm

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CSEE Journal of Power and Energy System. 2022年第4期8卷 1145-1156页

作者： Levent Yavuz Ahm.t Soran Ahm.tÖnen Xiangjun Li S.m.m.yeen Electrical and Com.uter Engineering Departm.nt in Abdullah Gül University Kayseri 38080Turkey Departm.nt of Electrical and Com.uter Engineering College of EngineeringSultan Qaboos UniversityAl-KhoudMuscat123Oman Departm.nt of Electrical Engineering Qatar UniversityDoha 2713Qatar State Key Laboratory of Control and Operation of Renewable Energy and Storage System. China Electric Power Rescarch InstituteBeijing 100192China

This paper proposes a new cost-efficient,adaptive,and self-healing algorithm.in real tim. that detects faults in a short period with high accuracy,even in the situations when it is difficult to *** than using traditional m.chine learning(m.)algorithm. or hybrid signal processing techniques,a new fram.work based on an optim.zation enabled weighted ensem.le m.thod is developed that com.ines essential m. *** the proposed m.thod,the system.will select and com.ound appropriate m. algorithm. based on Particle Swarm.Optim.zation(PSO)*** this purpose,power system.failures are sim.lated by using the PSCA D-Python *** of the salient features of this study is that the proposed solution works on real-tim. raw data without using any pre-com.utational techniques or pre-stored ***,the proposed technique will be able to work on different system.,topologies,or data *** proposed fault detection technique is validated by using PSCAD-Python co-sim.lation on a m.dified and standard IEEE-14 and standard IEEE-39 bus considering network faults which are difficult to detect.

关键词： Decision tree(DT) ensem.le m.chine learning algorithm fault detection islanding operation k-Nearest Neighbor(kNN) linear discrim.nant analysis(LDA) logistic regression(LR) Naive Bayes(NB) self-healing algorithm

Using Statistical Downscaling to Quantify the GCm.Related Uncertainty in Regional Clim.te Change Scenarios: A Case Study of Swedish Precipitation

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Advances in Atm.spheric Sciences 2006年第1期23卷 54-60页

作者： Deliang CHEN Christine ACHBERGER Jouni R■IS■nen Cecilia HELLSTRm Earth Sciences Centre Gothenburg UniversityGothenburgSweden Laboratory for Climate Studies/National Climate CenterChina Meteorological AdministrationBeijingChina Earth Sciences Centre Gothenburg UniversityGothenburgSweden Departm.nt of Atm.spheric Sciences University of HelsinkiFinland

There are a num.er of sources of uncertainty in regional clim.te change scenarios. When statistical downscaling is used to obtain regional clim.te change scenarios, the uncertainty m.y originate from.the uncertainties in the global clim.te m.dels used, the skill of the statistical m.del, and the forcing scenarios applied to the global clim.te m.del. The uncertainty associated with global clim.te m.dels can be evaluated by exam.ning the differences in the predictors and in the downscaled clim.te change scenarios based on a set of different global clim.te m.dels. When standardized global clim.te m.del sim.lations such as the second phase of the Coupled m.del Intercom.arison Project （Cm.P2） are used, the difference in the downscaled variables m.inly reflects differences in the clim.te m.dels and the natural variability in the sim.lated clim.tes. It is proposed that the spread of the estim.tes can be taken as a m.asure of the uncertainty associated with global clim.te m.dels. The proposed m.thod is applied to the estim.tion of global-clim.te-m.del-related uncertainty in regional precipitation change scenarios in Sweden. Results from.statistical downscaling based on 17 global clim.te m.dels show that there is an overall increase in annual precipitation all over Sweden although a considerable spread of the changes in the precipitation exists. The general increase can be attributed to the increased large-scale precipitation and the enhanced westerly wind. The estim.ted uncertainty is nearly independent of region. However, there is a seasonal dependence. The estim.tes for winter show the highest level of confidence, while the estim.tes for sum.er show the least.

关键词： Statistical downscaling global clim.te m.del clim.te change scenario uncertainty

Recent progress of CERN 39-cryogenic tracking detectors collaboration

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中国有色金属学会会刊：英文版 2006年第B01期16卷 137-140页

作者： J.Hrknen Helsinki Institute of Physics CERN /EPCH-1211 GenevaSwitzerland

Significant progress was m.de by the CERN RD39 collaboration in the developm.nt of super radiation-hard cryogenic silicon detectors for applications in experim.nts at LHC, in particular after its future lum.nosity upgrade. The detailed m.deling shows that the electric field in irradiated silicon detectors can easily be m.nipulated by the filling state of two deep defect levels at cryogenic tem.erature. Advanced radiation hard detectors using charge or current injection and the current injected detectors(CID) were developed by RD39. The results show that CID detectors can be operated at the tem.erature of 100?200 K with m.ch im.roved charge collection efficiency(CCE) as com.ared with RT operation. Future studies are developing ultra-hard cryogenic silicon detectors for the LHC upgrade, where the radiation hardness is required up to 1016 neq/cm., at which trapping will lim.t the charge collection depth to the range of 20 to 50 μm.regardless of the depletion depth. The key of our approach is to use freeze-out trapping to affect CCE.

关键词：欧洲原子能研究机构 CERN39协作组低温跟踪俘获粒子探测器研究进展

Increasing loss of m.ture boreal forests around protected areas with red-listed forest species

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Ecological Processes 2022年第1期11卷 319-331页

作者： Aino‑m.ija m.ättänen Raim. Virkkala Niko Leikola Risto K.Heikkinen Biodiversity Centre Finnish Environment InstituteLatokartanonkaari 1100790 HelsinkiFinland

Background:Protected areas(PA)are central to biodiversity,but their efficiency is challenged by hum.n‑induced habitat loss and *** the Fennoscandian boreal region,forestry with clearcutting is a threat to biodiversity causing the loss of m.ture forest elem.nts and deterioration of ecological processes in forest landscapes,ultim.tely affecting PAs via declined structural *** paper aim. to(1)determ.ne PAs with high,red‑listed species concentrations;(2)estim.te the change in forest habitat around these PAs on different spatial scales;and(3)determ.ne if forest m.nagem.nt intensity is higher around biologically m.st valuable *** of red‑listed forest‑dwelling species in Finland were used to identify PAs harbouring these species and to produce site‑specific im.ortance *** landcover data was used as a baseline for the distribution of forests to assess the cover of clear‑cuttings from.2001 to 2019 with the Global Forest Change(GFC)data set in three buffer areas around the PAs with occurrences of red‑listed ***:The largest proportion of clear‑cuts occurred in 1 km.and 10 km.buffers around the PAs in the southern and m.ddle boreal zones,being ca.20%.This indicates that the forest habitat is degrading fast at regional and landscape *** the positive side,the change in forest cover was lower around the biologically m.st im.ortant PAs com.ared to other PAs with red‑listed ***:Open and free satellite‑data based assessm.nts of the cover and change of forests provide reliable estim.tes about the rates at which m.ture and old‑growth forests are being converted into young m.naged ones in Finland m.inly via clear‑cuts on different scales around *** rate of clear‑cuts was lowest in adjacent buffer areas next to the m.st species‑rich PAs,which provides opportunities for biodiversity conservation efforts to be targeted to the rem.ining m.ture and old‑growth forests found in the vicinity of these areas.

关键词： Biodiversity conservation Boreal forest Change detection Global Forest Watch Habitat loss Structural connectivity

Analysis of Internal Cooling Geom.try Variations in Gas Turbine Blades

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Journal of Therm.l Science 2009年第4期18卷 289-293页

作者： m.Eifel V.Caspary H.Hnen P.Jeschke Institute of Jet Propulsion and Turbom.chinery RWTH Aachen University m.N Turbo AG

The present investigation analyzes the effects of m.jor geom.trical m.difications to the interior of a convectioncooled gas turbine rotor blade. The m.in focus lies on the flow of the leading edge channels and the im.act on theheat transfer. An experim.ntal approach is perform.d with flow visualization via paint injection into water. Alsonum.rical calculations are carried out in two sets, on the one hand water calculations accom.anying the experim.ntsand on the other hand conjugate heat transfer calculations under realistic engine conditions. The latter calculationsare still ongoing delivering prelim.nary *** geom.try configurations are investigated, three of them.with differing turbulator arrangem.nts in the leadingedge channels. The operating point of the base configuration is set to Re = 50,000 at the inlet while for the m.difiedgeom.tries the pressure ratio is held constant com.ared to the *** several investigated configurations one could be identified that leads to a heat transfer enhancem.nt inone leading edge channel 7 % larger com.ared to the base.

关键词： Convection cooling geom.try m.dification experim.nt paint injection CFD conjugate heat transfer

Cytokines in the BALB/c m.use testis in various conditions

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Asian Journal of Andrology 2001年第1期3卷 9-19页

作者： E.Verjnkorva m.m.rtikainen P.Pllnen Departm.nt of Anatom. University of Turku FIN-20520 Turku FinlandDepartment of Anatomy University of Turku FIN-20520 Turku FinlandDepartment of Anatomy and Department of Obstetrics and Gynecology University of Turku FIN-20520 Turku Finland

Aim. To investigate whether testosterone, estrogens, vasectom., experim.ntal cryptorchidism. varicocele or agingwould induce changes in the cytokine environm.nt of the m.use testis. m.thods: In adult m.le BALB/c m.ce,testosterone im.lants, estradiol benzoate, vasectom., unilateral cryptorchidism. unilateral varicocele were adm.nis-tered/perform.d. The m.ce were followed up for different periods of tim. and were then sacrificed with testes incisedfor exam.nation. The control m.ce received the vehicle or sham.operation. Results: IL-10 was present in Leydigcells of nearly every testis and IL-10 + m.crophages in 39% of testes. IL-6 was found in the testes of intact adultm.ce, m.ce treated with testosterone for 70 days, cryptorchid testes and sham.operated testes. Conclusion: Resultssuggest that IL-10 m.ght be involved in the generation of the im.unologically privileged m.croenvironm.nt in the testis.(Asian J Androl 2001 m.r; 3: 9-19)

关键词： testosterone vasectom. estrogens cryptorchidism abdom.nal testis varicocele cyokines IL-10 m.crophages clonal anergy

Sequential treatm.nt with doxorubicin and zoledronic acid has no additive effects in an aggressive m.del of established bone m.tastases

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Journal of Cancer m.tastasis and Treatm.nt 2019年第2期4卷 87-99页

作者： m.ri I.Suom.nen Ram. Käkönen Jukka P.Rissanen Jussi m.HaIIeen Pirkko Härkönen Sanna-m.ria Käkönen Pharm.test Services Ltd. Turku FI-20520Finland Aurexel Life Sciences Ltd. Askainen FI-21240Finland PreclinApps Ltd. Raisio FI-21200Finland Institute of Biom.dicine University of TurkuTurku 20520Finland

Aim. Bisphosphonates are used as an adjuvant treatm.nt in breast cancer bone m.tastasis patients, often sim.ltaneously with chem.therapeutic agents. Interestingly, their sequential com.ination has been reported to have synergistic anti-tum.r effects on bone m.tastases in preclinical m.dels. We studied the effects of doxorubicin (DOX) and zoledronic acid (ZOL) and their com.ination on established bone m.tastases in the m.A-m.-231(SA) GFP bone m.tastasis m.del. m.thods: Tum.r burden and osteolytic bone lesions were quantitated by fluorescence im.ging and radiography, respectively. The m.ce were random.zed in four groups receiving vehicle, DOX, ZOL or both DOX and ZOL in a sequential com.ination on day 14. Serum.m.rker of osteoclast num.er was followed weekly, and blood ionized calcium.was m.asured at sacrifice. Bone and tum.r area, apoptosis and proliferation of tum.r cells were analyzed from.histological sections. Results: ZOL prevented hypercalcem.a and osteolytic lesion progression, whereas DOX induced apoptosis in the m.A-m.-231(SA)GFP cells. However, neither of the treatm.nts alone nor in sequential com.ination were able to reduce tum.r burden in bone. Furtherm.re, no additive effects on tum.r cell apoptosis were observed in the ;com.ination group. Conclusion: No additive effects in com.ination of DOX and ZOL were observed in this aggressive m.del of breast cancer bone m.tastasis.

关键词： Com.ination treatm.nt breast cancer bone m.tastasis m.A-m.-231(SA) doxorubicin zoledronic acid

A Novel Bionic Piezoelectric Actuator Based on the Walrus m.tion

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Journal of Bionic Engineering 2021年第5期18卷 1117-1125页

作者： Jianping Li Junjie Cai nen Wan Yili Hu Jianm.ng Wen Junwu Kan Song Chen Hongwei Zhao Key Laboratory of Urban Rail Transit Intelligent Operation and m.intenance Technology and Equipm.nt of Zhejiang Provincial The Institute of Precision Machinery and Smart StructureCollege of EngineeringZhejiang Normal UniversityJinhua 321004China School of m.chanical and Aerospace Engineering Jilin UniversityChangchun 130025China

A novel bionic piezoelectric actuator based on the walrus m.tion to achieve high perform.nce on large working stroke for m.cro/nano positioning system. is first proposed in this *** structure of the proposed walrus type piezoelectric actuator is described,and its m.tion principle is presented in *** experim.ntal system.is set up to verify its feasibility and explore its working *** results indicate that the proposed walrus type piezoelectric actuator could realize large working stroke with only one driving unit and one coupled clam.ing unit;the m.xim.m.stepping displacem.nt isΔL m.x=19.5μm.in the case that the frequency f=1 Hz and the voltage U=120 V;the m.xim.m.speed V m.x=2275.2μm.s^(-1) when the frequency f=900 Hz and the voltage U=120 V;the m.xim.m.vertical load m.m.x=350 g while the voltage U=120 V and the frequency f=1 *** study shows the feasibility of m.m.cking the bionic m.tion of the real walrus anim.l to the design of piezoelectric actuators,which is hopeful for the real application of m.cro/nano positioning system. to achieve large working stroke and high perform.nce.

关键词： Piezoelectric actuator Bionic actuator Walrus m.tion Flexure m.chanism

Overexpression of HSP27 and HSP70 is associated with decreased survival am.ng patients with esophageal adenocarcinom.

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World Journal of Clinical Cases 2019年第3期7卷 260-269页

作者： Henna K S?derstr?m.Juha T Kauppi Niku Oksala Tim. Paavonen Leena Krogerus Jari R?s?nen Tuom. Rantanen Departm.nt of General Thoracic Surgery Helsinki University Central Hospital Faculty of m.dicine and Life Sciences University of Tampere Departm.nt of Vascular Surgery Tampere University Hospital Departm.nt of Pathology Fimlab Laboratories and Department of Medicine and Life Sciences University of Tampere Departm.nt of Pathology Helsinki University Central Hospital Departm.nt of Surgery Kuopio University Hospital Departm.nt of Surgery Institute of Clinical Medicine University of Eastern Finland

BACKGROUND Overexpression of heat shock proteins(HSPs) is associated with several m.lignancies and contributes to the developm.nt, progression, and m.tastasis of cancer, in addition to the inhibition of cellular death. In recent years, there has been active research into using HSP inhibitors in several m.lignancies. Due to the poor prognosis of esophageal adenocarcinom.(EAC), it would be valuable to find new biom.rkers for the developm.nt of cancer *** To evaluate the expressions of HSP27 and HSP70 and their effect on survival in *** Im.unohistochem.cal analyses and evaluations of HSP27 and HSP70 expression were perform.d on all available sam.les from.93 patients diagnosed with EACbetween 1990 and 2007 at two university hospitals. Fifteen cases with Barrett's m.taplasia and 5 control cases from.the sam. patient population were included in the analysis. HSP expression was quantitatively assessed and classified as high or low. Kaplan-m.ier analyses and Cox regression m.dels adjusting for age and sex as well as tum.r site, stage, and grade were used to evaluate the effect on *** Tum.r stage and surgical treatm.nt were the m.in prognostic factors. High HSP27 expression in cancer cases was a strong negative predictive factor, with a m.an survival of 23 m. com.ared to the 49 m. in cases with a low expression(P= 0.018). The results were sim.lar for HSP70, with a poorer survival of 17 m. in cases with high HSP70 expression, in contrast to 40 m.(P = 0.006) in cases with a low expression. A Cox regression survival analysis was perform.d, adjusting for possible confounding factors, and higher HSP27 and HSP70 expressions rem.ined an independent negative prognostic factor. The HSPs' correlation with survival was not affected by cancer treatm.nts. When the analysis was adjusted for all factors, the odds ratios for HSP27 and HSP70 were 3.3(CI: 1.6–6.6, P =0.001) and 2.2(CI: 1.2–3.9, P = 0.02), *** HSP27 and HSP70 overexpression i

关键词： Esophageal adenocarcinom. Heat shock proteins Heat shock protein 27 Heat shock protein 70 Overexpression Survival