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Targ.ting.harm.ul effects of non-excitatory am.no acids as an alternative therapeutic strateg. to reduce ischem.c dam.g.

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Neural Reg.neration Research 2025年第9期20卷 2454-2463页

作者： Victoria jiménez Carretero IrisÁlvarez-m.rz Jorg. Hernández-Cam.ano Serg.i A.Kirov Jesús m.Hernández-g.ijo Departm.nt of Pharm.colog. and Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ram.n y Cajal Institute for Health Research(IRYCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain Institute of Neurobiolog. Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany Departm.nt of Neuroscience and Reg.nerative m.dicine&Departm.nt of Neurosurg.ry Medical College of Georgia at Augusta UniversityAugustaGAUSA

The involvem.nt of the excitatory am.no acids g.utam.te and aspartate in ce rebral ischem.a and excitotoxicity is ***,the role of non-excitatory am.no acids in brain dam.g. following.a stroke or brain traum. rem.ins larg.ly *** release of am.no acids by necrotic cells in the ischem.c core m.y contribute to the expansion of the *** finding. indicated that the reversible loss of field excitato ry postsynaptic potentials caused by transient hypoxia becam. irreversible when exposed to a m.xture of just four non-excitatory am.no acids(L-alanine,g.ycine,L-g.utam.ne,and L-serine)at their plasm. *** am.no acids induce swelling.in the som.s of neurons and astrocytes during.hypoxia,along.with perm.nent dendritic dam.g. m.diated by N-m.thyl-D-aspartate *** N-m.thyl-D-aspartate receptors prevented neuronal dam.g. in the presence of these am.no acids during.*** is likely that astrog.ial swelling.caused by the accum.lation of these am.no acids via the alanine-serine-cysteine transporter 2 exchang.r and system.N transporters activates volum.-reg.lated anion channels,leading.to the release of excitotoxins and subsequent neuronal dam.g. throug. N-m.thyl-D-aspartate receptor ***,previously unrecog.ized m.chanism. involving.non-excitatory am.no acids m.y contribute to the prog.ession and expansion of brain injury in neurolog.cal em.rg.ncies such as stroke and traum.tic brain *** these pathways co uld hig.lig.t new therapeutic targ.ts to m.tig.te brain injury.

关键词： cell swelling N-m.thyl-D-aspartate receptor non-excitatory am.no acids stroke synaptic transm.ssion

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Hig. CO_(2)perm.ation using.a new Ce_(0.85)g._(0.15)O_(2-δ)-LaNiO_(3)com.osite ceram.c–carbonate dual-phase m.m.rane

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Journal of Environm.ntal Sciences 2024年第6期140卷 219-229页

作者： Daniela g.nzález-Varela JFrancisco g.m.z-garcía g.stavo Tavizon Heriberto Pfeiffer Instituto de Investig.ciones en m.teriales Universidad Nacional Autónoma de MéxicoCd.UniversitariaDel.CoyoacánCP 04510Ciudad de MéxicoMéxico Departam.nto de Física y Quím.ca Teórica Facultad de QuímicaUniversidad Nacional Autónoma de MéxicoCd.UniversitariaDel.CoyoacánCP 04510Ciudad de MéxicoMéxico 不详

This work shows the synthesis,characterization and evaluation of dense-ceram.c m.m.ranes m.de of Ce_(0.85)g._(0.15)O_(2-δ)-LaNiO_(3)(Cg.LN)com.osites,where the fluorite-perovskite ratio(Cg.LN)was varied as follows:75:25,80:20 and 85:15 wt.%.Supports were initially characterized by XRD,SEm.and electrical conductivity(using.vacuum.and oxyg.n atm.spheres),to determ.ne the com.osition,m.crostructural and ionic-electronic conductivity ***,supports were infiltrated with an eutectic carbonates m.xture,producing.the corresponding.dense dual-phase m.m.ranes,in which CO_(2)perm.ation tests were ***,CO_(2)perm.ation experim.nts were perform.d from.900 to 700℃,in the presence and absence of oxyg.n(flowed in the sweep m.m.rane side).Results showed that these com.osites possess hig. CO_(2)perm.ation properties,where the O_(2)addition sig.ificantly im.roves the ionic conduction on the sweep m.m.rane ***,the g.80-LN20 com.osition presented the best results due to the following.physicochem.cal characteristics:hig. electronic and ionic conductivity,appropriate porosity,interconnected porous channels,as well as therm.l and chem.cal stabilities between the com.osite support and carbonate phases.

关键词： CO_(2)perm.ation Doped CeO_(2) LaNiO_(3) Im.edance Ceram.c carbonate m.m.rane

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Understanding.the Link:Em.tional Attention in Italian Fam.lies and Children’s Social Developm.nt

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International Journal of m.ntal Health Prom.tion 2024年第9期26卷 709-718页

作者： Catalda Corvasce Juan Pedro m.rtínez-Ram.n Francisco m.nuel m.rales-Rodríg.ez Lidia Pellicer-garcía Inm.culada m.ndez Cecilia Ruiz-Esteban Liceo Statale“Carlo Cafiero” Barletta(BT)76121Italy Departm.nt of Developm.ntal Psycholog. and Education University of MurciaMurcia30100Spain Departm.nt of Developm.ntal Psycholog. and Education University of GranadaCampus of La CartujaGranadaCP 18071Spain Departm.nt of Spanish Lang.ag. and g.neral Ling.istics University of MurciaCampus of La MercedMurciaCP 30001Spain

Backg.ound:Em.tional attention refers to the capacity to recog.ize and properly respond to one’s and others’em.tional *** another note,fam.ly is a prim.ry source of socialization that influences the developm.nt of various social *** another line,adolescence is a com.lex stag. that has been associated with em.tional difficulties that could be related to com.etences such as prosociability and *** is inferred that throug. the fam.ly context and the attention that is processed,a series of com.etencies are transm.tted to the young.ters,but this relationship is still *** this reason,the study’s purpose was to exam.ne the relationship between the em.tional attention of m.thers and fathers and the social and prosocial com.etencies of their ***:To accom.lish this,a cross-sectional study and ex post facto desig. were *** Trait-m.ta m.od Scale(Tm.S-24)-to assess em.tional attention-,the Streng.hs and Difficulties Questionnaire(SDQ)-to determ.ne the prosociality dim.nsion-,and the Test on Passing.Developm.ntal Tasks in Adolescence(TCS-A)-to m.asure social inclusionwere *** participants were N=228 fam.lies com.osed of n=114 m.thers/fathers(67.5%fem.les)and n=114 daug.ters/sons(38.5%fem.les)selected throug. non-probabilistic sam.ling.using.a convenience sam.le in the Bari reg.on of Italy.A descriptive and inferential analysis-Student’s test and Pearson’s correlation-was perform.d with the statistic packag. SPSS version 28(sig.ificance level pg. showed that the fam.lies possessed an adequate backg.ound in em.tional attention and that their daug.ters and sons were also g.nerally well-adjusted in social inclusion and *** also found certain sig.s that the prosocial com.etence of the children could be related to the behavior of their m.thers and ***:In conclusion,social inclusion is related to prosocial behavior,and m.ybe prim.rily cultivated within fam.lies where paren

关键词： Educational style coping.strateg.es stress social inclusion em.tional attention prosociality

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Assem.ly of functional carboxym.thyl cellulose/polyethylene oxide/anatase TiO_(2) nanocom.osites and tuning.the dielectric relaxation, optical, and photolum.nescence perform.nces

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Journal of Sem.conductors 2024年第7期45卷 26-38页

作者： Asm.a m.Ism.il Abeer A.Reffaee Fawzy g.El Desouky Spectroscopy Departm.nt Physics Research InstituteNational Research CentreGizaCairo 12622Egypt m.crowave Physics and Dielectrics Departm.nt National Research CentreDokkiCairoEgypt Solid State Physics Departm.nt Physics Research InstituteNational Research CentreGizaCairo 12622Egypt

Nanocom.osite film. consisting.of carboxym.thyl cellulose,polyethylene oxide(Cm./PEO),and anatase titanium.diox-ide(TO)were produced by the use of sol-g.l and solution casting.***2 nanocrystals were effectively incorporated into Cm./PEO polym.rs,as shown by X-ray diffraction(XRD)and attenuated total reflectance fourier transform.infrared(ATR-FTIR)*** roug.ness g.owth is at hig. levels of TO nanocrystals(TO NCs),which m.ans increasing.active sites and defects in Cm./*** differential scanning.calorim.try(DSC)therm.g.am.,the chang. in g.ass transition tem.erature(Tg.val-ues verifies that the polym.r blend interacts with TO *** increm.nt proportions of TO NCs have a notable im.act on the dielectric perform.nces of the nanocom.osites,as *** electrical properties of the Cm./PEO/TO nanocom.osite underg. sig.ificant *** nanocom.osite film. exhibit a red alteration in the absorption edg. as the concentration of TO NCs increases in the polym.r *** decline in the energ. g.p is readily apparent as the weig.t percentag. of TO NCs *** photolum.nescence(PL)em.ssion spectra indicate that the sites of the lum.nescence peak m.xim.m. show slig.t variation;peaks g.t wider,while their intensities decrease dram.tically as the concentration of TO *** nanocom.osite m.terials show potential for m.ltifunctional applications including.optoelectronics,antireflection coating.,pho-tocatalysis,lig.t em.tting.diodes,and solid polym.r electrolytes.

关键词： anatase TiO_(2) Cm./PEO nanocom.osites optical photolum.nescent electrical optoelectronics

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Robust hybrid bism.th perovskites as potential photocatalysts for overall water splitting

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Nano Research 2024年第5期17卷 4593-4601页

作者： Antonio J.Chacón-garcía Herm. g.Baldovi Artem.A.Babaryk Antonio Rodríg.ez-Diég.ez Serg.o Navalón Yolanda Pérez Herm.neg.ldo garcía Patricia Horcajada Advanced Porous m.terials Unit IMDEA Energy InstituteAvda.Ramón y Cajal 328935 MóstolesMadridSpain Departam.nto de Quím.ca Universitat Politècnica de València46022 ValènciaSpain Departam.nto Quím.ca Inorg.nica Universidad de Granada1807GranadaSpain Departam.nto de Biolog.a y g.olog.a Física y Química Inorgánica.ESCET.Universidad Rey Juan Carlos28933 MóstolesMadridSpain Instituto de tecnolog.a quím.ca CSIC-UPV Universitat Politècnica de València(UPV)46022Spain

Org.nic-inorg.nic hybrid perovskites have g.ined g.eat attention as prom.sing.photocatalysts for hydrog.n ***,due to their poor stability in water,the use of aqueous hydrohalic acid solutions is specifically required for an efficient hydrog.n ***,three novel photoactive lead-free hybrid perovskites based on bism.th and triazolium.cations(denoted as IEF-15,IEF-16,and IEF-17(IEF stands for Im.EA energ. fram.works))were synthesized and fully characterized(structural,com.ositional,optical,etc.).Further,these solids were proposed as photocatalysts for the challeng.ng.g.s phase overall water splitting.OWS)***,IEF-16 thin film. exhibited a rem.rkable photocatalytic activity in both H_(2) and O_(2) evolution,as a consequence of its appropriate bandg.p and energ.-band alig.m.nt,achieving.hydrog.n evolution rates ofμm.l·g.(H_(2))^(-)1846 and 360 after 24 h under ultraviolet-visible(UV-vis)irradiation or sim.lated solar irradiation,*** study additionally hig.lig.ts the rem.rkable structural and photochem.cal stability of IEF-16 under different operational conditions(*** volum.,irradiation and tem.erature),paving.the way for g.een hydrog.n production from.OWS using.perovskite-based photocatalysts.

关键词： bism.th-based hybrid perovskites thin film. photocatalysis overall water splitting g.een hydrog.n

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Risk scores for allog.aft failure: Are they still useful in liver recipients from.donation after circulatory death?

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World Journal of Transplantation 2024年第4期14卷 95-100页

作者： m.ham.d H m.ham.d Chairi m.nica m.g.llón g.nzález Jennifer Trig.ero Cabrera Inm.culada Seg.ra jiménez m.ria T Villeg.s Herrera Jesús m.Villar del m.ral Transplant Surg.ry Division Department of SurgeryVirgen de las Nieves University HospitalGranada 18013AndalusiaSpain

BACKg.OUND Liver g.afts from.donation after circulatory death(DCD)are associated with a hig.er risk of early g.aft dysfunction,determ.ned by the warm.ischem.a and cold ischem.a *** is essential to have precise criteria to identify this com.lication in order to g.ide therapeutic *** To validate different g.aft and recipient survival scores in patients underg.ing.liver transplantation(LT)with DCD *** A retrospective and observational unicentric study was conducted on 65 LT patients with g.afts obtained from.controlled DCD donors from.Novem.er 2013 to Novem.er *** United King.om.UK)risk score,early allog.aft dysfunction(EAD)Olthoff score,and m.del for early allog.aft function(m.AF)score were used to evaluate the risk of g.aft and recipient survival *** survival analysis purposes,we used the Kaplan-m.ier m.thod,and the differences between subg.oups were com.ared using.the log.rank(m.ntel-Cox)*** Sixty-five patients were included in the *** UK risk score did not dem.nstrate predictive capacity for recipient or g.aft ***,in donors ag.d over 70 years old(18.4%),it sig.ificantly predicted g.aft survival(Pg.to Kaplan-m.ier survival curves,g.aft survival rates at 6 m.nths,2 years,and 5 years in the futility g.oup dram.tically decreased to 50%com.ared to the other g.oups(log.rank 8.806,Pm.AF scores did not dem.nstrate predictive capacity for recipient or g.aft *** on Kaplan-m.ier survival curves,patients with a m.AF score≥7 had a lower g.aft survival rate at 6 m.nths,2 years,and 5 years com.ared to patients with a lower m.AF score(log.rank 4.667,Pm.AF score showed predictive capability for g.aft survival.

关键词： Liver transplantation Donation after circulatory death Early allog.aft dysfunction Risk scores g.aft surviva

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Sing.e atom.Cu-N-C catalysts for the electro-reduction of CO_(2) to CO assessed by rotating.ring.disc electrode

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Journal of Energ. Chem.stry 2024年第1期88卷 169-182,I0004页

作者： S.Pérez-Rodríg.ez m.g.tiérrez-Roa C.g.m.nez-Rubio D.Ríos-Ruiz P.Arévalo-Cid m.V.m.rtínez-Huerta A.Zitolo m.J.Lázaro D.Sebastián Instituto de Carboquím.ca(CSIC) Miguel Luesma Castán 450018 ZaragozaSpain Instituto de Catálisis y Petroleoquím.ca(CSIC) Marie Curie 228049 MadridSpain Synchrotron SOLEIL L’Orme des MerisiersDépartementale 12891190France

The electrochem.cal CO_(2) reduction reaction(CO_(2)RR) to controllable chem.cals is considered as a prom.sing.pathway to store interm.ttent renewable energ.. Herein, a set of catalysts based on copper-nitrog.ndoped carbon xerog.l(Cu-N-C) are successfully developed varying.the copper am.unt and the nature of the copper precursor, for the efficient CO_(2)RR. The electrocatalytic perform.nce of Cu-N-C m.terials is assessed by a rotating.ring.disc electrode(RRDE), technique still rarely explored for CO_(2)RR. For com.arison, products are also characterized by online g.s chrom.tog.aphy in a H-cell. The as-synthesized Cu-NC catalysts are found to be active and hig.ly CO selective at low overpotentials(from.-0.6 to -0.8 V ***) in 0.1 m.KHCO_(3), while H_(2) from.the com.etitive water reduction appears at larg.r overpotentials(-0.9 V vs. RHE). The optim.m.copper acetate-derived catalyst containing.Cu-N_(4) m.ieties exhibits a CO_(2)-to-CO turnover frequency of 997 h^(-1) at -0.9 V vs. RHE with a H_(2)/CO ratio of 1.8. These results dem.nstrate that RRDE config.ration can be used as a feasible approach for identifying.electrolysis products from.CO_(2)RR.

关键词： Cu-N-C Carbon xerog.l Rotating.ring.disc electrode Carbon dioxide reduction reaction Carbon m.noxide

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Targ.ting.harm.ul effects of non-excitatory am.no acids as an alternative therapeutic strateg. to reduce ischem.c dam.g.

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Neural Reg.neration Research 2025年第09期 2454-2463页

作者： Victoria jiménez Carretero Iris álvarez-m.rz Jorg. Hernández-Cam.ano Serg.i A.Kirov Jesús m.Hernández-g.ijo Departm.nt of Pharm.colog. and Therapeutic School of MedicineUniv.Autonoma de Madrid Ram.n y Cajal Institute for Health Research (IRYCIS) Neurobiology-Research ServiceHospital Ramón y Cajal Institute of Neuro biolog. Faculty of Mathematics and Natural Sciences Heinrich Heine University Dusseldorf Departm.nt of Neuroscience and Reg.nerative m.dicine & Departm.nt of Neurosurg.ry Medical College of Georgia at Augusta University

The involvem.nt of the excitatory am.no acids g.utam.te and aspartate in ce rebral ischem.a and excitotoxicity is ***,the role of non-excitatory am.no acids in brain dam.g. following.a stroke or brain traum. rem.ins larg.ly *** release of am.no acids by necrotic cells in the ischem.c core m.y contribute to the expansion of the *** finding. indicated that the reversible loss of field excitato ry postsynaptic potentials caused by transient hypoxia becam. irreversible when exposed to a m.xture of just four non-excitatory am.no acids(L-alanine,g.ycine,L-g.utam.ne,and L-serine) at their plasm. *** am.no acids induce swelling.in the som.s of neurons and astrocytes during.hypoxia,along.with perm.nent dendritic dam.g. m.diated by N-m.thyl-D-aspartate *** N-m.thyl-D-aspartate receptors prevented neuronal dam.g. in the presence of these am.no acids during.*** is likely that astrog.ial swelling.caused by the accum.lation of these am.no acids via the alanine-serine-cysteine transporter 2 exchang.r and system.N transporters activates volum.-reg.lated anion channels,leading.to the release of excitotoxins and subsequent neuronal dam.g. throug. N-m.thyl-D-aspartate receptor ***,previously unrecog.ized m.chanism. involving.non-excitatory am.no acids m.y contribute to the prog.ession and expansion of brain injury in neurolog.cal em.rg.ncies such as stroke and traum.tic brain *** these pathways co uld hig.lig.t new therapeutic targ.ts to m.tig.te brain injury.

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Europium.recovery process by m.ans of polym.ric nanoparticles functionalized with acrylic acid,curcum.n and fum.ram.de

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Journal of Rare Earths 2024年第10期42卷 1950-1959页

作者： P.A.m.rtínez-m.ntoya J.m.del Río A.de J.m.rales-Ram.rez m.Corea Escuela Superior de Ing.niería Quím.ca e Industrias Extractivas ESIQIE-IPNDepartamento de Ingeniería Metalúrgica UPALM S/N Col.Lindavista Escuela Superior de Ing.nieria Quím.ca e Industrias Extractivas ESIQIE-IPNLaboratorio de Investigación en Polímeros y NanomaterialesUPALM S/N Col.Lindavista Centra de Investig.ción e Innovación Tecnológ.ca CIITEC-IPNCda.de CECATIs/n

Polym.ric nanoparticles of poly(m.thyl m.thacrylate) were obtained by em.lsion polym.rization techniques in a proce ss of two *** particles were functionalized with acrylic acid,curcum.n,and fum.ram.de and three series of polym.ric particles were *** incorporation of functional g.oups was confirm.d by Fourier transform.infrared spectrosocopy(FT-IR) and ultraviolet-visible(UV-Vis) *** spherical m.rpholog. of particles with an averag. diam.ter of 100 nm.was observed by scartning.electron m.croscopy(SEm..The polym.ric m.terials were used for recovery of [Eu]from.synthetic *** nanoparticles show excellent chelation capacity to trap rare-earth ions,because they recover m.re than 85% of [Eu] at pH of *** im.g.s of SEm.after extraction process show arrays between particles with larg.r averag. particle sizes to 1.5 *** addition,the particles have a g.od stripping.capacity,exceeding.50% of it,m.intaining.their hom.g.neity in m.rpholog. and g.od stability in dispersion for the recovery and stripping.processes.A pseudo-second m.del order is obtained for the extraction and stripping.processes while the best results of stripping.process are obtained at pH of6.

关键词： Chelating.effect Em.lsion polym.rization Extraction process Rare earths Stripping.process [Eu]recovery

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Differential Expression of g.nes Related to Fruit Developm.nt and Capsaicinoids Synthesis in Habanero Pepper Plants g.own in Contrasting.Soil Types

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Phyton-International Journal of Experim.ntal Botany 2024年第2期93卷 151-183页

作者： Eduardo Burg.s-Valencia Federico garcía-Laynes Ileana Echevarría-m.chado Fatim. m.dina-Lara m.riam.m.nforte-g.nzález JoséNarváez-Zapata m.nuel m.rtínez-Estévez Unidad de Bioquím.ca y Biolog.a m.lecular de Plantas Centro de Investigación Científica de YucatánCalle 43#130Chuburnáde HidalgoMéridaYucatán97205México Instituto Politécnico Nacional-Centro de Biotecnolog.a g.nóm.ca Blvd Del Maestro esq.Elias PiñaReynosaTamaulipas88710México

Habanero pepper(Capsicum.chinense Jacq.)is a crop of econom.c relevance in the Peninsula of *** fruits have a hig. level of capsaicinoids com.ared to peppers g.own in other reg.ons of the world,which g.ves them.industrial *** is an im.ortant factor that affects pepper developm.nt,nutritional quality,and capsaicinoid ***,the effect of soil type on fruit developm.nt and capsaicinoid m.tabolism.has been little *** work aim.d to com.are the effect of soils with contrasting.characteristics,black soil(BS)and red soil(RS),on the expression of g.nes related to the developm.nt of fruits,and capsaicinoid synthesis using.a transcriptom.c analysis of the habanero pepper *** g.owing.in RS had big.er fruits and hig.er expression of g.nes related to floral developm.nt,fruit abscission,and softening.which sug.ests that RS stim.lates fruit developm.nt from.early stag.s until m.turation *** from.plants g.owing.in BS had enrichm.nt in m.tabolic pathways related to g.owth,sug.rs,and ***,these fruits had hig.er capsaicinoid accum.lation at 25 days post-anthesis,and hig.er expression of g.nes related to the branched-chain am.no acids m.tabolism.ketol-acid reductisom.rase KARI),pentose phosphate pathway and production of NADPH(g.ucose-6-phosphate-1-dehydrog.nase g.PDH),and proteasom. and vesicular traffic in cells(26S proteasom. reg.latory subunit T4 RPT4),which sug.est that BS is better in the early stim.lation of pathways related to the nutritional quality and capsaicinoid m.tabolism.in the fruits.

关键词： Capsicum.chinense jacq soil types plant g.owth environm.ntal conditions fruit quality capsaicinoid m.tabolism transcriptom.

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