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Earthquake Engineering and Engineering Vibration 2024年第4期23卷 1029-1041页

作者： Zhu Wang Wu m.ng’er Xie Qiang Departm.nt of Structural Engineering Tongji UniversityShanghai 200092China Key Laboratory of Perform.nce Evolution and Control for Engineering Structures(Tongji University) Shanghai 200092China

Cem.nted and m.chanically clam.ed types of end fittings(fitting-C and fitting-m.are com.only used in transform.r *** the Luding m. 6.8 earthquake that occurred in China on Septem.er 5,2022,all transform.r bushings with the two types of end fittings in a 500 kV substation were ***-earthquake field investigations were conducted,and the failures of the two types of bushings were *** elem.ntary sim.lation m.dels of the transform.r-bushing system. were developed to sim.late the engineering failures,and further com.ute their seism.c responses for *** results indicate that the hitch lugs of the connection flange are structurally harm.ul to seism.c ***-m.can decrease the bending stiffness of the bushing due to the flexible sealing rubber *** it provides a m.re flexible connection that dissipates energy,the peak accelerations and relative displacem.nts at the top of the bushing are significantly lower than those of the bushing with *** with fitting-C,fitting-m.transfers the high-stress areas from.the connection flange to the root of the porcelain,so the latter becom.s the m.st vulnerable ***-m.increases the failure risk of the low-strength porcelain,indicating the unsuitability of applying it in high-intensity fortification regions.

关键词： transform.r bushing end fitting Luding earthquake,engineering failure seism.c responses

Nanom.dicine targeting ferroptosis to overcom. anticancer therapeutic resistance

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Science China(Life Sciences) 2024年第1期67卷 19-40页

作者： Jing Cai Xiaoding Xu Phei er Saw Guangdong Provincial Key Laboratory of m.lignant Tum.r Epigenetics and Gene Regulation Guangdong-Hong Kong Joint Laboratory for RNA MedicineMedical Research CenterSun Yat-sen Memorial HospitalSun Yat-sen UniversityGuangzhou 510120China Nanhai Translational Innovation Center of Precision Im.unology Sun Yat-sen Memorial HospitalSun Yat-sen UniversityFoshan 528200China

A potential reason for the failure of tum.r therapies is treatm.nt *** to chem.therapy,radiotherapy,and im.unotherapy continues to be a m.jor obstacle in clinic,resulting in tum.r recurrence and *** m.jor m.chanism. of therapy resistance are inhibitions of cell deaths,like apoptosis and necrosis,through drug inactivation and excretion,repair of DNA dam.ge,tum.r heterogeneity,or changes in tum.r m.croenvironm.nt,*** studies have shown that ferroptosis play a m.jor role in therapies resistance by inducing phospholipid peroxidation and iron-dependent cell *** ferroptosis inducers in com.ination with clinical treatm.nt techniques have been used to enhance the effect in tum.r ***,versatile ferroptosis nanoinducers exhibit an extensive range of functions in reversing therapy resistance,including directly triggering ferroptosis and feedback ***,we provide a detailed description of the design,m.chanism.and therapeutic application of ferroptosis-m.diated synergistic tum.r *** also discuss the prospect and challenge of nanom.dicine in tum.r therapy resistance by regulating ferroptosis and com.ination therapy.

关键词： ferroptosis cancer therapy therapy resistance nanoinducers

Prospects of the m.lti-channel Photom.tric Survey Telescope in the Cosm.logical Application of Type Ia Supernovae

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Research in Astronom. and Astrophysics 2024年第4期24卷 183-191页

作者： Zhenyu Wang Jujia Zhang Xinzhong er Jinm.ng Bai Yunnan Observatories Chinese Academy of SciencesKunming 650216China University of Chinese Academ. of Sciences Beijing 100049China Key Laboratory for the Structure and Evolution of Celestial Objects Chinese Academy of SciencesKunming 650216China International Centre of Supernovae Yunnan Key LaboratoryKunming 650216China South-Western Institute for Astronom. Research Yunnan UniversityKunming 650500China

The m.lti-channel Photom.tric Survey Telescope(m.phisto)is a real-tim.,three-color photom.tric system.designed to capture the color evolution of stars and transients *** telescope system.can be crucial in cosm.logical distance m.asurem.nts of low-redshift(low-z,z■0.1)Type Ia supernovae(SNe Ia).To optim.ze the capabilities of this instrum.nt,we perform.a com.rehensive sim.lation study before its official operation is scheduled to *** considering the im.act of atm.spheric extinction,weather conditions,and the lunar phase at the observing site involving the instrum.ntal features,we sim.late light curves of SNe Ia obtained by *** best strategy in the case of SN Ia cosm.logy is to take the im.ge at an exposure tim. of 130 s with a cadence of 3 *** this condition,m.phisto can obtain hundreds of high-quality SNe Ia to achieve a distance m.asurem.nt better than 4.5%.Given the on-tim. spectral classification and m.nitoring of the Lijiang 2.4 m.Telescope at the sam. observatory,m.phisto,in the whole operation,can significantly enrich the well-calibrated sam.le of supernovae at low-z and im.rove the calibration accuracy of high-z SNe Ia.

关键词： (stars:)supernovae:general (cosm.logy:)cosm.logical param.ters telescopes

Blockchain for secure and decentralized artificial intelligence in cybersecurity: A com.rehensive review

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BLOCKCHAIN-RESEARCH AND APPLICATIONS 2024年第3期5卷 184-208页

作者： Saleh, Ahm.d m. Sham.an Univ Tabuk Dept Informat Technol Tabuk 47512 Saudi Arabia

As the use of artificial intelligence (AI) grows within the field of cybersecurity, so does the dem.nd for secure and decentralized AI system. to protect against potential cyber threats. Blockchain technology has em.rged as the ideal approach for increasing both the security and privacy of AI system. since it provides decentralized and im.utable data storage. This system.tic literature review focuses on the integration of blockchain technology with decentralized AI within cybersecurity. It provides a com.rehensive taxonom. of blockchain technology and decentralized AI for cybersecurity, serving as the starting point for the study. This paper begins with an overview of blockchain technology and its possible uses in cybersecurity and also analyzes its challenges and opportunities. Decentralized AI is also covered in the study, along with its potential advantages and difficulties in decentralized AI cybersecurity. Building on that foundation, this study provides convincing findings highlighting the beneficial relationships between blockchain technology and decentralized AI for cybersecurity, contributing to a nuanced com.rehension of their integration. m.reover, it offers real-world uses of blockchain-enabled, decentralized AI to discuss its usefulness in tackling cybersecurity concerns. Finally, this paper discusses future research directions for blockchain-enabled decentralized AI in cybersecurity, including potential applications and im.lications of this technology in the field, em.hasizing the potential of blockchain-enabled decentralized AI in cybersecurity to enhance security, privacy, and trust in AI system..

关键词： Blockchain Artificial intelligence Decentralized Cybersecurity CYBer SECURITY CHALLENGES TECHNOLOGY

Facile synthesis of sam.rium.and cerium.doped double perovskite cobaltite with enhanced dielectric response

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Journal of Rare Earths 2024年第7期42卷 1317-1327,I0005页

作者： Yasir Abbas m.Kam.an m.Anis-ur-Rehm.n Applied Therm.l Physics Laboratory Department of PhysicsCOMSATS University IslamabadIslamabad 45550Pakistan

The investigation of Sm.Ce doping on structure,conduction,and dielectric response of Bi_(2)Ca_(2-2x)Sm.(x)CexCoO_(6)(x=0.000,0.025,0.050,0.075)(BCSCCO)are *** the specim.ns were synthesized by a facile synthesis technique nam.d the co-precipitation route.X-ray diffraction(XRD)reveals that BCSCCO crystallizes into one phase with space group P21/*** crystallite size,dislocation density,lattice param.ters,lattice strain,unit cell volum.,and bulk density were determ.ned using XRD *** structural properties of Bi_(2)Ca_(2)CoO_(6)were exam.ned using calculations based on the density functional *** and experim.ntal values discrepancy is less than 1%.A scanning electron m.croscope was used for perform.ng a m.crostructural *** SEm.im.ges dem.nstrate the hom.geneous distribution of grains with a range of sizes(0.054-0.090μm..The alternating current(ac)conductivity,dielectric perm.ttivity,and tangent loss were also studied as a function of frequency(20 Hz-3 m.z)at different tem.eratures(100-500℃).All synthesized sam.les were exam.ned using non-linear Debye's function to determ.ne their spreading factor and relaxation *** specim.n with the lowest crystallite size(∼23 nm.exhibits a high dielectric perm.ttivity(∼3.80×10^(6)).The conduction m.chanism.was exam.ned in the studied sam.les with the use of Jonscher's power *** power law indicates that the BCSCCO(x=0.000,0.025)follows correlated barrier hopping,whereas the x=0.050 and 0.075 com.ositions follow non-overlapping polaron *** studied specim.n Bi_(2)Ca_(1.9)0Sm.(0.05)0Ce_(0.05)_(0)CoO_(6)with the highest density(∼5.65 g/cm.(3))displays a high electrical conductivity(∼46.1 S/cm..These findings correspond to those published for ceram.cs m.de from.calcium.cobaltite using solid-state reactions(5.0-26.0 S/cm..

关键词： Bism.th calcium.sam.rium.cerium.cobaltite (BCSCCO) Spreading factor Conduction m.chanism Rare earths

Green hydrogen energy production: current status and potential

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CLEAN ENerGY 2024年第2期8卷 1-7页

作者： m.ka, Ali O. m. m.hm.od, m.bbashar Libyan Ctr Res & Dev Saharian Com.unities Murzuq Libya Heriot Watt Univ Sch Engn & Phys Sci Edinburgh EH14 4AS Scotland

The technique of producing hydrogen by utilizing green and renewable energy sources is called green hydrogen production. Therefore, by im.lem.nting this technique, hydrogen will becom. a sustainable and clean energy source by lowering greenhouse gas em.ssions and reducing our reliance on fossil fuels. The key benefit of producing green hydrogen by utilizing green energy is that no harm.ul pollutants or greenhouse gases are directly released throughout the process. Hence, to guarantee all of the environm.ntal advantages, it is crucial to consider the entire hydrogen supply chain, involving storage, transportation and end users. Hydrogen is a prom.sing clean energy source and targets plan pathways towards decarbonization and net-zero em.ssions by 2050. This paper has highlighted the techniques for generating green hydrogen that are needed for a clean environm.nt and sustainable energy solutions. m.reover, it sum.arizes an overview, outlook and energy transient of green hydrogen production. Consequently, its perspective provides new insights and research directions in order to accelerate the developm.nt and identify the potential of green hydrogen production. Hydrogen is a prom.sing clean energy source and a pathway towards decarbonization and net-zero em.ssions by 2050. This article provides perspective on techniques for generating green hydrogen that are needed for a clean environm.nt and sustainable energy solutions. Graphical Abstract

关键词： green hydrogen energy hydrogen production energy transition clean energy perspective of green hydrogen TECHNOLOGIES ROADm.P

Cooperative Target Fencing of m.ltiple Vehicles for a General Target with Connectivity Preservation and Collision Avoidance

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Journal of System. Science & Com.lexity 2024年第1期37卷 136-151页

作者： PAN Zini CHEN Ben m Departm.nt of m.chanical and Autom.tion Engineering The Chinese University of Hong KongHong KongChina

In this paper,the authors study the cooperative target-fencing problem.for n-dim.nsional system. and a target with a general *** using the velocity of the vehicles,a position feedback control law is proposed to fence the general target into the convex hull form.d by the ***,the dynam.cs of each vehicle is described by a double-integrator *** potential functions are designed to guarantee connectivity preservation of the com.unication network and collision avoidance am.ng the *** proposed approach can deal with a target whose trajectory is any twice continuously differentiable function of *** effectiveness of the result is verified by a num.rical exam.le.

关键词： m.lti-agent system. networked system. target fencing

Identification of two com.ound heterozygous GNRHR m.tations in two siblings with congenital hypogonadotropic hypogonadism

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Asian Journal of Andrology 2024年第1期26卷 120-122页

作者： Xiao-Bin Wang Ping Chen Xue-er Yu Zu-Liang Yao Ting-Chao Guo Bo-Chen Pan Center for Reproductive m.dicine Department of Obstetrics and GynecologyShengjing Hospital of China Medical UniversityShenyang 110004China NuProbe Shanghai 200433China Urology Surgery of The Affiliated Reproductive Hospital of China m.dical University and Liaoning Key Laboratory of Reproductive Health Liaoning Research Institute of Family Planning(The Affiliated Reproductive Hospital of China Medical University)Shenyang 110031China NHC Key Laboratory of Reproductive Health and m.dical Genetics China Medical UniversityShenyang 110122China

DearEditor,Congenital hypogonadotropic hypogonadism.CHH)is a rare genetic disease characterized by gonadotropin-releasing horm.ne(GnRH)deficiency or insufficiency and norm.l hypothalam.c-pituitary structures,resulting in defective sexual m.turation or/and infertility.!CHH presents as a variety of nonreproductive phenotypes,such as renal hypoplasia,dental hypoplasia,or oculom.tor abnorm.lities.

关键词： pogon com.ound ism

Fuel cell stack design and m.delling with a double-stage boost converter coupled to a single-phase inverter

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CLEAN ENerGY 2024年第1期8卷 188-196页

作者： Elnagi, Basem.E. Ism.iel, Ahm.d m. m.nsour, Hany S. E. Abd-Alwahab, m. N. Suez Canal Univ Fac Engn Elect Engn Dept Ismailia 41522 Egypt

A com.rehensive proton-exchange m.m.rane fuel cell stack m.del was developed and integrated with a two-stage DC/DC boost converter. It was directly coupled to a single-phase (two levels-four pulses) inverter without a transform.r. The pulse-width m.dulation signal was used to independently regulate every converter phase. The converter was m.delled using a m.TLAB (R)/Sim.link (R) environm.nt and an appropriate voltage control m.thod. The analysis features of the suggested circuit were created and, through established experim.nts, the sim.lation results were verified. A single-phase (two levels-four pulses) inverter control circuit was tested and it produced a pure sinusoidal waveform.with voltage control. It m.tches the voltage of the network in term. of am.litude and frequency. A sinusoidal pulse-width m.dulation approach was perform.d using a single-phase (two levels-four pulses) pulse-width m.dulation inverter. The results dem.nstrated an enhancem.nt in the standard of the output wave and tuned the dead tim. with a reduction of 63 m. s com.ared with 180 m. s in conventional techniques. A com.rehensive m.del of a proton-exchange m.m.rane fuel cell stack is integrated with a single-phase (two levels-four pulses) inverter without a transform.r. Pulse-width m.dulation is used to independently regulate every converter phase. As a result, the dead tim. is reduced com.ared to conventional techniques. Graphical Abstract

关键词： PEm.fuel cell pulse-width m.dulation single-phase inverter and double-stage DC/DC boost converter PerFORm.NCE SYSTEm

Use of ketam.ne for severe asthm. exacerbation in a pregnant patient with persistent bronchospasm. A case report

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Em.rgency and Critical Care m.dicine 2024年第3期4卷 130-133页

作者： Johnson m. Abbas m. Abdo J. m.nsour m. Jones J. Pharm.cy Departm.nt Beaumont Health Dearborn MI United States Em.rgency Center Beaumont Health Dearborn MI United States

Background Estim.ted 4%-8% of pregnancies are com.licated by asthm.. Adequate m.nagem.nt in this population is critical to m.nim.ze com.lications. Patients presenting with asthm. exacerbation are typically m.naged with standard bronchodilators and system.c corticosteroids. However, additional agents m.y be used in patients with refractory asthm. exacerbation. Ketam.ne has been used in refractory bronchospasm. although its efficacy in published literature is heterogeneous. Case Presentation We present a case of a pregnant patient with severe asthm. exacerbation refractory to standard and salvage treatm.nt who achieved term.nation of bronchospasm.with ketam.ne infusion. Conclusion After receiving ketam.ne infusion for several days, the patient had im.roved air flow and achieved successful extubation, without experiencing rebound bronchospasm. Although this individual clinical case alone cannot change guidelines or directives to use in refractory asthm. exacerbations, it offers a possible treatm.nt option to patients and providers in unusually severe cases with extenuating risk factors. © Wolters Kluwer Health, Inc. All rights reserved.

关键词： Asthm. Bronchospasm. Case Report Ketam.ne Pregnancy