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m.ta.olic com.lica.ions of psychotropic m.dica.ions in psychia.ric disorders:Em.rging role of de novo lipogenesis a.d thera.eutic considera.ion

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World Journa. of Psychia.ry 2024年第6期14卷 767-783页

作者： m.ha.0}a. m.khan Za. a.i khan m.hsin a.i khan La.ora.ory of Tra.sla.iona. Neurology a.d m.lecula. Psychia.ry Department of BiotechnologyEra’s Lucknow Medical College and Hospitaland Faculty of ScienceEra UniversityLucknow 226003India Era.s Lucknow m.dica. College a.d Hospita. Era UniversityLucknow 226003India

a.though significa.t a.va.ces ha.e been m.de in understa.ding the pa.hophysiology of psychia.ric disorders(PDs),thera.eutic a.va.ces ha.e not been very *** psychotropic m.dica.ions ca. reduce cla.sica. sym.tom. in pa.ients with PDs,their long-term.use ha. been reported to induce or exa.gera.e va.ious pre-existing m.ta.olic a.norm.lities including dia.etes,obesity a.d non-a.coholic fa.ty liver disea.e(Na.LD).The m.cha.ism.s)underlying these m.ta.olic a.norm.lities is not clea.;however,lipid/fa.ty a.id a.cum.la.ion due to enha.ced de novo lipogenesis(DNL)ha. been shown to reduce m.m.ra.e fluidity,increa.e oxida.ive stress a.d infla.0}a.ion lea.ing to the developm.nt of the a.orem.ntioned m.ta.olic ***,em.rging evidence suggest tha. DNL dysregula.ion a.d fa.ty a.id a.cum.la.ion could be the m.jor m.cha.ism. a.socia.ed with the developm.nt of obesity,dia.etes a.d Na.LD a.ter long-term.trea.m.nt with psychotropic m.dica.ions in pa.ients with *** support of this,severa. a.junctive drugs com.rising of a.ti-oxida.ts a.d a.tiinfla.0}a.ory a.ents,tha. a.e used in trea.ing PDs in com.ina.ion with psychotropic m.dica.ions,ha.e been shown to reduce insulin resista.ce a.d developm.nt of *** conclusion,the a.ove evidence suggests tha. DNL could be a.potentia. pa.hologica. fa.tor a.socia.ed with va.ious m.ta.olic a.norm.lities,a.d a.new a.enue for tra.sla.iona. resea.ch a.d thera.eutic drug designing in PDs.

关键词： Psychotropic m.dica.ions m.ta.olic com.lica.ions De novo lipogenesis Obesity Dia.etes Non-a.coholic fa.ty liver disea.e

Cervica. Ca.cer Prediction Em.owered with Federa.ed m.chine Lea.ning

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Com.uters, m.teria.s & Continua 2024年第4期79卷 963-981页

作者： m.ha.0}a. Um.r Na.ir Om.r Ka.sem.Kha.il Ka.a.0}th a.eeq Ba.sa.0}Sa.eem.lla. a.m.ga.wy m.a.khan khan m.ha.0}a. a.na. Depa.tm.nt of Com.uter Sciences Bahria University Lahore CampusLahore54000Pakistan Fa.ulty of Inform.tion Technology Liwa CollegeAbu Dhabi20009UAE Depa.tm.nt of Com.uting Skyline University CollegeSharjah999041UAE Depa.tm.nt of Com.uter Science Taibah UniversityMedina42315Saudi Arabia Ripha. School of Com.uting a.d Innova.ion Faculty of ComputingRiphah International UniversityLahore54000Pakistan Depa.tm.nt of Softwa.e Faculty of Artificial Intelligence and SoftwareGachon UniversitySeongnam13120Korea

Cervica. ca.cer is a. intrusive ca.cer tha. im.ta.es va.ious wom.n a.ound the world. Cervica. ca.cer ra.ks in thefourth position beca.se of the lea.ing dea.h ca.se in its prem.ture sta.es. The cervix which is the lower end of theva.ina.tha. connects the uterus a.d va.ina.form. a.ca.cerous tum.r very slowly. This pre-m.ture ca.cerous tum.rin the cervix is dea.ly if it ca.not be detected in the ea.ly sta.es. So, in this delinea.ed study, the proposed a.proa.huses federa.ed m.chine lea.ning with num.rous m.chine lea.ning solvers for the prediction of cervica. ca.cer totra.n the weights with va.ying neurons em.owered fuzzed techniques to a.ign the neurons, Internet of m.dica.Things (Iom.) to fetch da.a.a.d blockcha.n technology for da.a.priva.y a.d m.dels protection from.ha.a.dousa.ta.ks. The proposed a.proa.h a.hieves the highest cervica. ca.cer prediction a.cura.y of 99.26% a.d a.0.74%m.sprediction ra.e. So, the proposed a.proa.h shows the best prediction results of cervica. ca.cer in its ea.ly sta.eswith the help of pa.ient clinica. records, a.d a.l m.dica. professiona.s will get beneficia. dia.nosing a.proa.hesfrom.this study a.d detect cervica. ca.cer in its ea.ly sta.es which reduce the overa.l dea.h ra.io of wom.n due tocervica. ca.cer.

关键词： Cervica. ca.cer federa.ed m.chine lea.ning neurons blockcha.n technology

Dorm.ncy studies on India. horse-chestnut (a.sculus indica.Colebr.) under Ka.hm.r conditions

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Forestry Studies in China 2010年第1期12卷 41-44页

作者： m.m.a. m.JEED m. a. khan a.ta.0}sh Ba.HIR a. H. m.GHa. Fa.ulty of Forestry Sher-e-Kashmir University of Agricultural Science & Technology of Kashmir

Studies were ca.ried out in the Fa.ulty of Forestry, Sher-e-Ka.hrnir University of a.ricultura. Sciences ＆ Technology of Ka.hm.r, Sha.im.r of India.during 2006 a.d 2007. The India. horse-chestnut （a.sculus indica.Colebr.）, loca.ly known a. ＂Ha.udun＂, is one of the m.re im.orta.t broa.-lea.ed tree species of the Ka.hm.r va.ley. No deep dorm.ncy wa. observed in m.ture seeds. However, the seeds rem.ined dorm.nt due to unfa.ora.le environm.nta. conditions preva.ling a.ter seed dispersa.. Both trea.m.nts of cold stra.ifica.ion were significa.tly superior to the control conditions, i.e., no stra.ifica.ion which showed no germ.na.ion during the test period of 30 d. The effects of the two trea.m.nts （cold stra.ifica.ion for 15 or 30 d） a.so differed significa.tly. Germ.na.ion wa. found to increa.e with a. increa.e in the tim. of cold stra.ifica.ion. Chilling trea.m.nts of seeds for 30 d showed m.xim.m.ger- m.na.ion of 80%, requiring the shortest tim. for germ.na.ion, i.e., 20.51 d with a.m.xim.m.eva.ua.ed germ.na.ion va.ue of 14.88. The other trea.m.nt with 15 d chilling showed lower germ.na.ion of 60%, requiring a.m.xim.m.num.er of germ.na.ion da.s （27.31 d） with lower germ.na.ion va.ue of 3.26.

关键词： a.sculus indica.Colebr. seeds dorm.ncy stra.ifica.ion germ.na.ion

Correla.ion of tum.r-a.socia.ed m.cropha.e density a.d proportion of m. subtypes with the pa.hologica. sta.e of colorecta. ca.cer

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World Journa. of Ga.trointestina. Oncology 2024年第5期16卷 1878-1889页

作者： Fouzia.Fa.a. m.ha.0}a. a.sa.a. khan Sum.yya.Sha.a.a.Ra.m. Ra.hid m.ha.0}ed m.ba.a. Depa.tm.nt of Pa.hology Jinnah Medical and Dental CollegeKarachi 74800SindhPakistan Depa.tm.nt of Genera. Surgery Sindh Institute of Urology&Transplantation(SIUT)Karachi 74200SindhPakistan Depa.tm.nt of Pa.hology Bahria University of Health SciencesKarachi 74400SindhPakistan Depa.tm.nt of Pa.hology SIUTKarachi 74200SindhPakistan

Ba.KGROUND Colorecta. ca.cer(CRC)is a.preva.ent globa. m.ligna.cy with com.lex prognostic ***-a.socia.ed m.cropha.es(Ta.0})ha.e shown pa.a.oxica. a.socia.ions with CRC surviva.,pa.ticula.ly concerning the m. *** We a.m.d to esta.lish a.sim.lified protocol for qua.tifying m.-like Ta.0} a.d explore their correla.ion with clinicopa.hologica. *** a.cross-sectiona. study included histopa.hologica. a.sessm.nt of pa.a.finem.edded tissue blocks obta.ned from.43 CRC *** CD68 a.d CD163 im.unohistochem.stry,we qua.tified Ta.0} in tum.r strom. a.d front,focusing on m. ***,histopa.hologica.,a.d clinica. pa.a.0}ters were *** Ta.0}density wa. significa.tly higher a. the tum.r front,with the m. proportion three tim.s grea.er in both *** tum.r front ha. a.higher m. proportion,which correla.ed significa.tly with a.va.ced tum.r sta.e(P=0.04),pa.hologica. noda. involvem.nt(P=0.04),a.d lym.hova.cula. inva.ion(LVI,P=0.01).However,no significa.t a.socia.ion wa. found between the m. proportion in the tum.r strom. a.d clinicopa.hologica. *** Our study introduces a.sim.lified protocol for qua.tifying m.-like Ta.0} in CRC tissue *** dem.nstra.ed a.significa.t correla.ion between a. increa.ed m. proportion a. the tum.r front a.d a.va.ced tum.r sta.e,noda. involvem.nt,a.d *** suggests tha. m.-like Ta.0} m.ght serve a. potentia. indica.ors of disea.e progression in CRC,wa.ra.ting further investiga.ion a.d potentia. clinica. a.plica.ion.

关键词： Colorecta. ca.cer m.cropha.es Tum.r strom. m. subset Tum.r front Tum.r sta.e Lym.hova.cula. inva.ion Prognosis Tum.r-a.socia.ed m.cropha.es Im.unohistochem.stry

a.celera.ion of sola. wind pa.ticles due to inertia. a.fvén wa.es

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Com.unica.ions in Theoretica. Physics 2024年第6期76卷 137-141页

作者： Kira. Ba.ool Im.a. a.khan m.Sha.0}r a.dul Ka.ir S a.a. Theoretica. Physics Depa.tm.nt National Centre for PhysicsIslamabad 44000Pakistan Depa.tm.nt of Spa.e Sciences Institute of Space TechnologyIslamabad 44000Pakistan Spa.e a.d a.trophysics Resea.ch La.(Sa.L) National Center of GIS and Space Applications(NCGSA)Islamabad 44000Pakistan Sa.a.0}Cha.r Department of PhysicsGC University LahoreKatchery RoadLahorePunjab 54000Pakistan Depa.tm.nt of Spa.e Science a.d CSPa. University of Alabama in HuntsvilleHuntsvilleAL 35899United States of America

Ga.ning a. understa.ding of the effects a.d dyna.0}cs of the sola. wind is crucia. for the study of spa.e wea.her,Ea.th's m.gnetosphere,spa.ecra.t protection,the dyna.0}cs of the Sola. System.a.d va.ious other *** show tha. a.fvén wa.es effectively tra.sfer energy to resona.t *** study dem.nstra.es how inertia. a.fvén wa.es deliver their energy to resona.t pla.m. pa.ticles in different sola. environm.nts under certa.n *** a.a.ysis shows tha. inertia. a.fvén wa.es experience m.re ra.id da.0}ing with increa.ing pa.a.lel wa.enum.er,a.0}ient m.gnetic field strength,a.d pa.ticle num.er density,coupled with a.decrea.e in *** ra.e of energy tra.sfer to resona.t pa.ticles intensifies with higher tem.era.ures a.d reduced pa.a.lel wa.enum.er a.d pa.ticle num.er *** with higher initia. velocities a.tively pa.ticipa.e in La.da. da.0}ing,especia.ly in regions with a.stronger a.0}ient m.gnetic field.

关键词： sola. wind inertia. a.fven wa.es resona.t pa.ticles

m.ssive Dira. pa.ticles ba.ed on ga.ped gra.hene with Rosen-m.rse potentia. in a.uniform.m.gnetic field

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Chinese Physics B 2024年第8期33卷 170-178页

作者： a.Ka.a.i a.ireza.a.0}ni m.a.Ra.0}a.pour Depa.tm.nt of Physics Ayatollah Amoli BranchIslamic Azad UniversityAmolIran

We explore the ga.ped gra.hene structure in the two-dim.nsiona. pla.e in the presence of the Rosen-m.rse potentia. a.d a. externa. uniform.m.gnetic *** order to describe the corresponding structure,we consider the propa.a.ion of electrons in gra.hene a. rela.ivistic ferm.on qua.i-pa.ticles,a.d a.a.yze it by the wa.e functions of two-com.onent spinors with pseudo-spin sym.etry using the Dira. ***,to solve a.d a.a.yze the Dira. equa.ion,we obta.n the eigenva.ues a.d eigenvectors using the Legendre differentia. *** tha.,we obta.n the bounded sta.es of energy depending on the coefficients of Rosen-m.rse a.d m.gnetic potentia.s in term. of qua.tum.num.ers of principa. n a.d spin-orbit ***,the va.ues of the energy spectrum.for the ground sta.e a.d the first excited sta.e a.e ca.cula.ed,a.d the wa.e functions a.d the corresponding proba.ilities a.e plotted in term. of coordina.es *** wha. follows,we explore the ba.d structure of ga.ped gra.hene by the m.dified dispersion rela.ion a.d write it in term. of the two-dim.nsiona. wa.e vectors K_(x) a.d K_(y).Fina.ly,the energy ba.ds a.e plotted in term. of the wa.e vectors K_(x) a.d K_(y) with a.d without the m.gnetic term.

关键词： m.ssive Dira. equa.ion Rosen–m.rse potentia. Legendre polynom.a. ga.ped gra.hene pseudospin sym.etry

m.cropla.tic Im.a.ts on Greenhouse Ga.es Em.ssions in Terrestria. Ecosystem.

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Open Journa. of Soil Science 2024年第1期14卷 64-80页

作者： Ta.een Fa.im. khan m. m. Gola.0}Ra.ba.i Depa.tm.nt of Soil Water and Environment University of Dhaka Dhaka Bangladesh La.ca.ter Environm.nt Centre University of Lancaster Lancaster UK

m.cropla.tics ca. influence globa. clim.te cha.ge by regula.ing the em.ssions of greenhouse ga.es from.different ecosystem.. The effects of m.cropla.tics in terrestria. ecosystem. a.e still not well studied pa.ticula.ly greenhouse ga.es em.ssions. Thus, we conducted a.la.ora.ory experim.nt over a.period of 90 da.s with two types of m.cropla.tics (differing in their chem.ca. structure), high density polyethylene (HDPE) a.d low density polyethylene (LDPE), which were a.plied to the soil a. a.ra.e of 0% to 0.1% (w/w). The overa.ching a.m.wa. to investiga.e the effects of m.cropla.tic type, m.cropla.tic concentra.ion a.d da.s of exposure on greenhouse ga.es em.ssions. We a.so used origina. a.d a.tificia.ly wea.hered m.cropla.tics (the sa.0} HDPE a.d LDPE) to m.ke a.com.a.ison of greenhouse ga.es em.ssions between the origina. m.cropla.tics trea.ed soils a.d the soils trea.ed with wea.hered m.cropla.tics. Our findings showed tha. HDPE a.d LDPE m.cropla.tics significa.tly increa.ed the em.ssions of greenhouse ga.es from.the soil tha. tha. of the control soils. Em.ssions were increa.ed with the increa.es in the level of m.cropla.tic in the soil. The wea.hered m.cropla.tic em.tted grea.er qua.tity of greenhouse ga.es com.a.ed to tha. of the origina. m.cropla.tics. In contra.t to a.low initia. em.ssion qua.tity, the em.ssions were gra.ua.ly increa.ed a. the term.na.ion of the experim.nt. Our experim.nt on the em.ssions of greenhouse ga.es from.the soil vis-à-vis m.cropla.tic a.ditions indica.ed tha. the m.cropla.tic increa.ed the em.ssions of greenhouse ga.es in terrestria. ecosystem., a.d perva.ive m.cropla.tic im.a.ts m.y ha.e consequences for the globa. clim.te cha.ge. Greenhouse ga.es em.ssions from.the soil not only depend on the type a.d concentra.ion of the m.cropla.tic, but a.so on the da.s of exposure to the m.cropla.tic.

关键词： m.cropla.tic Clim.te Cha.ge Greenhouse Ga. Type Concentra.ion

Enha.cem.nt of coercivity,perm.a.ility,a.d dielectric properties of Co_(0.2)Zn_(0.3)Ni_(0.5)Eu_(x)Fe_(2-x)O_(4) ferrites for m.m.ry a.d high frequency devices

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Journa. of Ra.e Ea.ths 2024年第6期42卷 1128-1135,I0005页

作者： I.Sa.da. m.D.Hossa.n m.S.Sikder m.N.I.khan m.R.Ra.m.n Physics Discipline Khulna UniversityKhulna9208Bangladesh Depa.tm.nt of Physics Khulna University of Engineering&TechnologyKhulna9203Bangladesh Depa.tm.nt ofCom.uter Science a.d Engineering Northern University of Business&Technology KhulnaKhulna9100Bangladesh m.teria. Science Division Atomic Energy CentreDhaka1000Bangladesh

Spinel cubic ferrites ha.e huge a.plica.ions in m. m.ry a.d high frequency *** the im.rovem.nt of these m.dern devices,the m.gnetic coercivity,perm.a.ility,a.d dielectric properties of a.ferrite a.e the im.orta.t *** a.ticle focuses on im.roving the m.gnetic coercivity,m.gnetic perm.a.ility,a.d dielectric properties of Co_(0.2)Zn_(0.3)Ni_(0.5)Eu_(x)Fe_(2-x)O_(4) ferrites,where x=0.00,0.06,a.d *** X-ra. diffra.tion(XRD),Fourier tra.sform.infra.ed spectroscopy(FTIR),field em.ssion sca.ning electron m.croscopy(FESEm.,energy dispersive X-ra.(EDX),vibra.ing sa.0}le m.gnetom.ter(VSm.,a.d a. im.eda.ce a.a.yzer were used to cha.a.terize the structura.,m.gnetic,a.d dielectric properties of the *** XRD pa.terns indica.e the form.tion of spinel cubic structure of the sa.0}les with a.seconda.y pea.(EuFeO_(3))for Eu doped *** densities a.d porosities of the sa.0}les follow a. inverse trend,where the doped sa.0}les’la.tice pa.a.0}ters a.e increa.ed with the increm.nt of ra.e ea.th Eu *** FTIR a.a.ysis a.so proves the spinel cubic pha.e of the *** a.era.e gra.n size of the ferrites is obta.ned via.FESEm.im.ges,a.d it is increa.ed from.121 to 198 *** a.a.ysis confirm. tha. doping of the Eu content a.so cha.ges other hysteresis loop properties of Co_(0.2)Zn_(0.3)Ni_(0.5)Eu_(x)Fe_(2-x)O_(4) ***,the coercivity of the Eu doped sa.0}les is grea.er tha. tha. of the m.ther a.loy(x=0.00).The EDX study shows tha. there is no im.urity conta.0}na.ion in the *** perm.a.ility a.d dielectric m.a.urem.nts show a. im.roved qua.ity fa.tor of the Eu-doped sa.0}les with low m.gnetic a.d dielectric *** dependent resistivity a.d im.eda.ce a.a.ysis a.so show the im.roved *** the observed properties of the sa.0}les,a.l the investiga.ed ferrites m.ght be strong ca.dida.es for potentia. a.plica.ions in m.m.ry devices,m.gnetic sensors,a.d high frequency a.plica.ions.

关键词： Ferrites Ra.ee a.ths Coercivity Perm.a.ility EDX Resistivity

m.turity indices of India. horse-chestnut (a.sculus indica.Colebr.) seeds under tem.era.e Ka.hm.r conditions

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Forestry Studies in China 2010年第1期12卷 45-48页

作者： m.m.a. m.JEED m. a. khan a.ta.0}sh Ba.HIR K. N. Qa.Sa. Fa.ulty of Forestry Sher-e-Kashmir University of Agricultural Science & Technology of Kashmir

Our study on m.turity indices of a.sculus indica.Colebr. seeds wa. conducted under tem.era.e Ka.hm.r conditions in 2006. Seed collection wa. sta.ted from.15 July a.d continued until the m.tura.ion of seeds in Decem.er. The seeds were ha.vested fortnightly from.identified trees a.d on ea.h collection da.e m.turity indices, viz. seed color, seed weight, m.isture content, seed dim.nsion, specific gra.ity a.d germ.na.ion percenta.e were recorded. The study revea.ed tha. a. the tim. of m.turity （Nov.-Dec.） the seed color wa. a.shiny chocola.e brown, with a.m.isture content of 58.37% a.d a.specific gra.ity of 0.82. Germ.na.ion wa. m.xim.m.（80%） a. its m.turity with a.m.xim.m.seed weight of 52.03 g per seed. We recom.end tha. the seeds should be collected before their na.ura. disposa..

关键词： a.sculus indica.Colebr. m.turity indices seed weight seed color specific gra.ity