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Impact of Zika virus non-structural protein mutations on hippocampal damage

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Neural Regeneration Research 2025年第8期20卷 2307-2308页

作者： Larissa m.G.Cassiano Roney S.Coimbra Neurogenômica/Imunopatologia Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunologia Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIkV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurological effects,notably microcephaly in newborns,first reported during the 2015 epidemic in ***,its impact goes beyond fetal and neonatal abnormalities,also affecting the central nervous system(CNS)in both children and adults,leading to enduring cognitive and behavioral impairments.

关键词： damage fetal neonatal

40Ar/39Ar and Rb-Sr Geochronology of the Qingyang Batholith,Anhui Province,China

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Acta Geochimica 1985年第3期4卷 220-235页

作者：陈江峰周泰禧 k.a. FOLAND Geochemical Division University of Science and Technology of China Geochemical Division University of Science and Technology of China Department of Geology and mineralogy The Ohio State University Columbus Ohio 43210 USA

The geochronology and genesis of the Qingyang batholith were investigated using40Ar/39Arand Rb-Sr isotopic *** Qingyang is a composite batholith consisting of two majorrock types granodiorite and granite in the Yangtze fold belt.40Ar/39Ar spectra for biotite andamphibole separates are internally *** concordance of the minerals and spectra indi-cate no thermal disturbance of the ages,and rapid cooling of the *** granodiorite hasan age of 137.6±1.4 *** the granite 122.7±1.2 ***-rock Rb-Sr analysis yieldsages consistent with the40Ar/39Ar ***,the Qingyang batholith was formed in two ma-jor stages in the late Jurassic and early *** batholith is not Triassic as was pre-viously ***40Ar/39Ar analysis of two granodiorite samples has preciseIy documented a 1.0 *** age difference between these *** factors could account for this difference,but different emplacement times seem most *** granodiorite and granite show lit-de variation in initial87Sr/86Sr ratio（about 0.7085）.The high initial Sr ratios suggest that themagmas were formed by anatexis of older crustal materials.

关键词： Ar and Rb-Sr Geochronology of the Qingyang Batholith,Anhui Province,China Ar Sr Rb

On plane Λ-fractional linear elasticity theory

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Theoretical & Applied mechanics Letters 2020年第4期10卷 270-275页

作者： k.a.Lazopoulos A.k.Lazopoulos 14 Theatrou Str. Rafina19009 Greece mathematical Sciences Department Hellenic Army Academy Vari16673 Greece

Non-local plane elasticity problems are discussed in the context of Λ-fractional linear elasticity theory. Adapting the Λ-fractional derivative along with the Λ-fractional space, where geometry and mechanics are valid in the conventional way, non-local plane elasticity problems are solved with the help of biharmonic functions. Then, the results are transferred into the initial *** are presented to homogeneous and the fractional beam bending problem.

关键词： Plane elasticity problems Λ-fractional linear elasticity theory Λ-fractional derivative Λ-fractional space Biharmonic function Fractional beam bending

Arctic sea-ice extent: No record minimum in 2023 or recent years

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Atmospheric and Oceanic Science Letters 2025年第1期18卷 52-55页

作者： Ola m.Johannessen Tor I.Olaussen Nansen Scientific Society BergenNorway Nansen Environmental and Remote Sensing Center BergenNorway

Arctic sea-ice extent reaches its minimum each year in September. On 11 September 2023 the minimum was 4.969 million square kilometers(***^(2)). This was not a record low, which occurred in 2012, when the minimum was 4.175 ***^(2), 0.794 ***^(2) less than the minimum in 2023. However, the ice extent had decreased by 0.432 ***^(2) compared with 2022. Nevertheless, the summer melting in 2023 was remarkably less than expected when considering the strong heat waves in the atmosphere and ocean, with record temperatures set around the world. In general, there is a high correlation between the long-term decrease in sea-ice extent and the increasing CO_(2) in the atmosphere, where the increase of CO_(2) in recent decades explains about 80% of the decrease in sea ice in September, while the remainder is caused by natural variability.

关键词： Sea ice Arctic minimum ice Climate

Insights from an academic endeavor into central nervous system drug discovery

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Neural Regeneration Research 2025年第6期20卷 1717-1718页

作者： Lieve van Veggel An m.Voets Tim Vanmierlo Rudy Schreiber BIOmED Biomedical Research Institute Faculty of Medicine and Life SciencesHasselt UniversityHasseltBelgium Department of Psychiatry and Neuropsychology Division of Translational NeuroscienceEuropean Graduate School of NeuroscienceSchool for Mental Health and NeuroscienceMaastricht UniversityMaastrichtThe Netherlands Section of Psychopharmacology Neuropsychology and PsychopharmacologyFaculty of Psychology and NeuroscienceMaastricht UniversityMaastrichtThe Netherlands University mS Center(UmSC) Hasselt-PeltBelgium

Historically,"big pharma"did most central nervous system drug discovery R&D ***,in modern times their"management reductionism"resulted in disappointing pipelines and pharma resided to(late)development,regulatory approval,and marketing(Thong,2015).This had significant consequences for financing and executing research,resulting in a larger role for funding by governments and patient-organizations and a shift of research to academia(mazzucato,2013).

关键词： academic approval consequences

Neurocircuit regeneration by extracellular matrix reprogramming

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Neural Regeneration Research 2025年第8期20卷 2300-2301页

作者： Shengzhang Su Ian N.Levasseur kimberly m.Alonge Department of medicinal Chemistry University of WashingtonSeattleWAUSA Department of Chemistry University of WashingtonSeattleWAUSA Department of medicine University of Washington Medicine Diabetes InstituteSeattleWAUSA

The brain's extracellular matrix(ECm),which is comprised of protein and glycosaminoglycan(GAG)scaffolds,constitutes 20%-40% of the human brain and is considered one of the largest influencers on brain cell functioning(Soles et al.,2023).Synthesized by neural and glial cells,the brain's ECm regulates a myriad of homeostatic cellular processes,including neuronal plasticity and firing(miyata et al.,2012),cation buffering(moraws ki et al.,2015),and glia-neuron interactions(Anderson et al.,2016).Considering the diversity of functions,dynamic remodeling of the brain's ECm indicates that this understudied medium is an active participant in both normal physiology and neurological diseases.

关键词： matrix programming

Transport mechanism in chemically reactive hybrid nanofluid flow containing gyrotactic micro-organisms over a curved oscillatory surface

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Applied mathematics and mechanics(English Edition) 2025年第1期46卷 177-192页

作者： m.NAVEED m.ImRAN T.ASGHAR Z.ABBAS Department of mathematics Division of Science and TechnologyUniversity of Education Department of mathematics The Islamia University of Bahawalpur

This paper examines the transport analysis, including both heat transfer and mass transfer, in hybrid nanofluid flow containing gyrotactic microorganisms towards a curved oscillatory surface. The influence of magnetic fields is also inspected in terms of their physical characteristics. To depict the phenomena of transport, modified versions of both Fick's and Fourier's laws are used. Additionally, the characteristics of both heterogeneous and homogeneous chemical reactions are also incorporated. Utilizing a curvilinear coordinate system, the flow problem is formulated as partial differential equations(PDEs)for momentum, concentration, microorganism field, and energy. An analytical solution to the obtained flow equations is achieved utilizing the homotopy analysis method(HAm).The effects of significant flow parameters on the pressure and microorganism fields, velocity, oscillation velocity, concentration, and temperature distributions are shown via graphs. Furthermore, the variations in skin friction, mass transfer rate, heat transfer rate, and local motile number due to different involved parameters are presented in tables and are analyzed in detail. Graphical results indicate that the curves of velocity and temperature fields are enhanced as the values of the solid volume fraction variables *** is also verified that the concentration rate field decreases as the values of the homogeneous reaction strength parameter and the radius of curvature parameter increase, and it increases with the Schmidt number and the heterogeneous reaction strength *** outcomes show a favorable response of the motile number to advanced values of the Peclet number, the Schmidt number, the microorganism difference parameter, and the bio-convective Lewis number.

关键词： Peclet number

Dissipative dynamics of an entangled three-qubit system via non-Hermitian Hamiltonian: Its correspondence with markovian and non-markovian regimes

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Chinese Physics B 2021年第3期30卷 283-292页

作者： m Rastegarzadeh m k Tavassoly Laser and Optics Group Faculty of PhysicsYazd UniversityYazd 89195-741Iran

We investigate an entangled three-qubit system in which only one of the qubits experiences the decoherence effect by considering a non-Hermitian Hamiltonian,while the other two qubits are isolated,i.e.,do not interact with environment,***,the time evolution of the density matrix(for the pure as well as mixed initial density matrix)and the corresponding reduced density matrices are obtained,by which we are able to utilize the dissipative non-Hermitian Hamiltonian model with markovian and non-markovian regimes via adjusting the strange of the non-Hermitian term of the total Hamiltonian of the under-considered system.

关键词： non-Hermitian Hamiltonian entanglement concurrence measure markovian and non-markovian regimes

Predicting maximum Lifespan Limits at mean menopausal Age

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Journal of mathematical Research with Applications 2025年第1期 133-142页

作者： m.SUmATHI S.ANTONY CARLA Department of mathematics N.M.S.S.Vellaichamy Nadar College Research Scholar (Part-time) Madurai Kamaraj University

The age at which a woman enters natural menopause has also been associated to death from any cause. menopause is a natural component of aging that happens between the ages of 45 and 55, with the average menopausal age being 51. Previous research has revealed the age at which women reach menopause, but there is no evidence to support the link between menopause and longevity. We made a study in assessing the limits of maximum lifespan at menopausal age in our previous article. In this paper, we aim to predict the maximum lifespan of women at mean menopausal age.

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