检索结果-南通市图书馆

Dendritic cell deficiencies persist seven months after SARS-CoV-2 infection

在线全文

学校读者我要写书评

暂无评论

Cellular & molecular Immunology 2021年第9期18卷 2128-2139页

作者： Alberto Pérez-Gómez Joana Vitallé Carmen Gasca-Capote Alicia Gutierrez-Valencia maría Trujillo-Rodriguez Ana Serna-Gallego Esperanza muñoz-muela maría de los Reyes Jiménez-Leon mohamed Rafii-El-Idrissi Benhnia Inmaculada Rivas-Jeremias Cesar Sotomayor Cristina Roca-Oporto Nuria Espinosa Carmen Infante-Domínguez Juan Carlos Crespo-Rivas Alberto Fernández-Villar Alexandre Pérez-González Luis Fernando López-Cortés Eva Poveda Ezequiel Ruiz-mateos Josémiguel Cisneros Sonsoles Salto-Alejandre Judith Berastegui-Cabrera Pedro Camacho-martínez Carmen Infante-Domínguez marta Carretero-Ledesma Juan Carlos Crespo-Rivas Eduardo márquez Josémanuel Lomas Claudio Bueno Rosario Amaya JoséAntonio Lepe Jerónimo Pachón Elisa Cordero Javier Sánchez-Céspedes manuela Aguilar-Guisado Almudena Aguilera Clara Aguilera Teresa Aldabo-Pallas Verónica Alfaro-Lara Cristina Amodeo Javier Ampuero maría Dolores Avilés maribel Asensio Bosco Barón-Franco Lydia Barrera-Pulido Rafael Bellido-Alba máximo bernabeu-wittel Candela Caballero-Eraso macarena Cabrera Enrique Calderón Jesús Carbajal-Guerrero manuela Cid-Cumplido Yael Corcia-Palomo Juan Delgado Antonio Domínguez-Petit Alejandro Deniz Reginal Dusseck-Brutus Ana Escoresca-Ortega Fátima Espinosa Nuria Espinosa michelle Espinoza Carmen Ferrándiz-millón marta Ferrer Teresa Ferrer Ignacio Gallego-Texeira Rosa Gámez-mancera Emilio García Horacio García-Delgado manuel García-Gutiérrez maría Luisa Gascón-Castillo Aurora González-Estrada Demetrio González Carmen Gómez-González Rocío González-León Carmen Grande-Cabrerizo Sonia Gutiérrez Carlos Hernández-Quiles Inmaculada Concepción Herrera-melero marta Herrero-Romero Luis Jara Carlos Jiménez-Juan Silvia Jiménez-Jorge mercedes Jiménez-Sánchez Julia Lanseros-Tenllado Carmina López Isabel López Álvaro López-Barrios Luis F.López-Cortés Rafael Luque-márquez Daniel macías-García Guillermo martín-Gutiérrez Luis martín-Villén Josémolina Aurora morillo maría Dolores Navarro-Amuedo Dolores Nieto-martín Francisco Ortega maría Paniagua-García Amelia Peña-Rodríguez E Clinical Unit of Infectious Diseases Microbiology and Preventive MedicineInstitute of Biomedicine of Seville(IBiS)Virgen del Rocío University HospitalCSICUniversity of SevilleSevilleSpain Department of medical Biochemistry Molecular Biologyand ImmunologySchool of MedicineUniversity of SevilleSevilleSpain Pneumology Service Galicia Sur Health Research Instituto(IIS Galicia Sur)SERGAS-UVigoVigoSpain Infectious Diseases Unit Department of Internal MedicineComplexo HospitalarioUniversitario de VigoIIS Galicia SurSERGAS-UVigoVigoSpain Group of Virology and Pathogenesis Galicia Sur Health Research Institute(IIS Galicia Sur)-Complexo Hospitalario Universitario de VigoSERGAS-UVigoVigoSpain Unit of Infectious Diseases Microbiologyand Preventive MedicineVirgen del Rocío University HospitalSevilleSpain Institute of Biomedicine of Seville(IBiS) Virgen del Rocío University Hospital/CSIC/University of SevilleSevilleSpain medico-Surgical Unit of Respiratory Diseases Virgen del Rocío University HospitalSevilleSpain Unit of Emergencies Virgen del Rocío University HospitalSevilleSpain Intensive Care Unit Virgen del Rocío University HospitalSevilleSpain Department of medicine University of SevilleSevilleSpain Cardiology and Cardiovascular Surgery Unit Virgen del Rocío University HospitalSevilleSpain Rheumatology Unit Virgen del Rocío University HospitalSevilleSpain Internal medicine Unit Virgen del Rocío University HospitalSevilleSpain Digestive and Hepatobiliary Unit Virgen del Rocío University HospitalSevilleSpain Neurology and Clinical Neurophysiology Unit Virgen del Rocío University HospitalSevilleSpain Endocrinology and Nutrition Unit Virgen del Rocío University HospitalSevilleSpain Urology and Nephrology Unit Virgen del Rocío University HospitalSevilleSpain Unit of Clinical Investigation and Clinical Trials Virgen del Rocío University HospitalSevilleSpain

Severe Acute Respiratory Syndrome Coronavirus(SARS-CoV)-2 infection induces an exacerbated inflammation driven by innate immunity *** cells(DCs)play a key role in the defense against viral infections,for instance plasmacytoid DCs(pDCs),have the capacity to produce vast amounts of interferon-alpha(IFN-α).In COVID-19 there is a deficit in DC numbers and IFN-αproduction,which has been associated with disease *** this work,we described that in addition to the DC deficiency,several DC activation and homing markers were altered in acute COVID-19 patients,which were associated with multiple inflammatory ***,previously hospitalized and nonhospitalized patients remained with decreased numbers of CD1c+myeloid DCs and pDCs seven months after SARS-CoV-2 ***,the expression of DC markers such as CD86 and CD4 were only restored in previously nonhospitalized patients,while no restoration of integrinβ7 and indoleamine 2,3-dyoxigenase(IDO)levels were *** findings contribute to a better understanding of the immunological sequelae of COVID-19.

关键词： SARS-CoV-2 COVID-19 Dendritic cell Long-COVID

measure of Segments which Intersect a Convex Body from Rotational Formulae

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Acta mathematica Sinica,English Series 2015年第2期31卷 345-352页

作者： ximo GUAL-ARNAU Silena HEROLD-GARCA Departament de matemàtiques-INIT Universitat Jaume I. 12071-CastellSpain Departamento de Computacin Universidad de Oriente. 90900-Santiago de CubaCuba

Classical problems in integral geometry and geometric probability involve the kinematic measure of congruent segments of fixed length within a convex body in R3. We give this measure from rotational formulae; that is, from isotropic plane sections through a fixed point. From this result we also obtain a new rotational formula for the volume of a convex body; which is proved to be equivalent to the wedge formula for the volume.

关键词： Convex body flower integral geometry stereology rotational formulae segment supportset

maize forage aptitude: Combining ability of inbred lines and stability of hybrids

在线全文

学校读者我要写书评

暂无评论

The Crop Journal 2014年第6期2卷 407-418页

作者： Luis máximo Bertoia mónica Beatriz Aulicino Department of Plant Production Faculty of Agrosciences National University of Lomas de Zamora Camino de Cintura km 21832 Lomas de Zamora Buenos Aires Argentina Department of Genetics Faculty of Agrosciences National University of Lomas de Zamora Camino de Cintura km 2 1832 Lomas de ZamoraBuenos Aires Argentina Santa Catalina Plant Breeding Institute National University of La Plata CC 4 1836 Llavallol Buenos Aires Argentina

Breeding of forage maize should combine improvement achieved for grain with the specific needs of forage hybrids. Production stability is important when maize is used for silage if the planting area is not in the ideal agronomic environment. The objectives of the present research were:(i) to quantify environmental and genetic and their interaction effects on maize silage traits;(ii) to identify possible heterotic groups for forage aptitude and suggest the formation of potential heterotic patterns, and(iii) to identify suitable inbred line combinations for producing hybrids with forage aptitude. Forty-five hybrids derived from diallelic crosses(without reciprocals) among ten inbred lines of maize were evaluated in this study. Combined ANOVA over environments showed differences between genotypes(G), environments(E), and their interactions(GEI). Heritability(H2), and genotypic and phenotypic correlations were estimated to evaluate the variation in and relationships between forage traits. Postdictive and predictive AmmI models were fitted to determine the importance of each source of variation, G, E, and GEI, and to select genotypes simultaneously on yield, quality and stability. A predominance of additive effects was found in the evaluated traits. The heterotic pattern Reid-BSSS × Argentine flint was confirmed for ear yield(EY) and harvest index(HI). High and broad genetic variation was found for stover and whole plant traits. Some inbred lines had genes with differential breeding aptitude for ear and stover. Stover and ear yield should be the main breeding objectives in maize forage breeding.

关键词： Zea mays L. Forage maize Combining ability GEI interaction Stover and ear digestibility

Nonlinear forced vibration in a subcritical regime of a porous functionally graded pipe conveying fluid with a retaining clip

在线全文

学校读者我要写书评

暂无评论

Applied mathematics and mechanics(English Edition) 2025年第1期46卷 101-122页

作者： m.GHOLAmI m.EFTEKHARI Department of mechanical Engineering Shahid Bahonar University of Kerman

This study examines the nonlinear behaviors of a clamped-clamped porous pipe made of a functionally graded material(FGm) that conveys fluids and is equipped with a retaining clip, focusing on primary resonance and subcritical dynamics. The nonlinear governing equations for the FGm pipe are derived by the extended Hamilton's principle, and subsequently discretized through the application of the Galerkin *** direct method of multi-scales is then used to solve the derived equations. A thorough analysis of various parameters, including the clip stiffness, the power-law index, the porosity, and the clip location, is conducted to gain a comprehensive understanding of the system's nonlinear dynamics. Through the analysis of the first natural frequency, the study highlights the influence of the flow velocity and the clip stiffness, while the comparisons with metallic pipes emphasize the role of FGm composition. The examination of the forced response curves reveals saddle-node bifurcations and their dependence on parameters such as the detuning parameter and the power-law index, offering valuable insights into the system's nonlinear resonant behavior. Furthermore, the frequency-response curves illustrate the hardening nonlinearities influenced by factors such as the porosity and the clip stiffness, revealing nuanced effects on the system response and resonance characteristics. This comprehensive analysis enhances the understanding of nonlinear behaviors in FGm porous pipes with a retaining clip, providing key insights for practical engineering applications in system design and optimization.

关键词：

Transmission FTIR derivative spectroscopy for estimation of furosemide in raw material and tablet dosage form

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Acta Pharmaceutica Sinica B 2014年第5期4卷 376-383页

作者： máximo Gallignani Rebeca A.Rondón JoséF.Ovalles maría R.Brunetto Laboratorio de Espectroscopia molecular Departamento de QuímicaFacultad de CienciasUniversidad de Los AndesMérida 5101-AVenezuela Departamento de Análisis y Control Facultad de Farmacia y BioanálisisUniversidad de Los AndesMérida 5101-AVenezuela

A Fourier transform infrared derivative spectroscopy(FTIR-DS)method has been developed for determining furosemide(FUR)in pharmaceutical solid dosage *** method involves the extraction of FUR from tablets with N,N-dimethylformamide by sonication and direct measurement in liquid phase mode using a reduced path length *** general,the spectra were measured in transmission mode and the equipment was configured to collect a spectrum at 4 cm^(-1) resolution and a 13 s collection time(10 scans co-added).The spectra were collected between 1400 cm^(-1) and 450 cm^(-1).Derivative spectroscopy was used for data processing and quantitative measurement using the peak area of the second order spectrum of the major spectral band found at 1165 cm^(-1)(SO_(2) stretching of FUR)with baseline *** method fulfilled most validation requirements in the 2 mg/mL and 20 mg/mL range,with a 0.9998 coefficient of determination obtained by simple calibration model,and a general coefficient of variation mean recovery for the proposed assay method resulted within the(100±3)%over the 80%–120% range of the target *** results agree with a pharmacopoeial method and,therefore,could be considered interchangeable.

关键词： FTIR Derivative spectroscopy Furosemide Frusemide Pharmaceutical analysis

Neurogenesis dynamics in the olfactory bulb:deciphering circuitry organization, function, and adaptive plasticity

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第6期20卷 1565-1581页

作者： moawiah m.Naffaa Department of Psychology and Neuroscience Duke UniversityDurhamNCUSA Department of Cell Biology Duke University School of MedicineDurhamNCUSA

Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons. The generation of these new neurons in the olfactory bulb supports both structural and functional plasticity, aiding in circuit remodeling triggered by memory and learning processes. However, the presence of these neurons, coupled with the cellular diversity within the olfactory bulb, presents an ongoing challenge in understanding its network organization and function. moreover,the continuous integration of new neurons in the olfactory bulb plays a pivotal role in regulating olfactory information processing. This adaptive process responds to changes in epithelial composition and contributes to the formation of olfactory memories by modulating cellular connectivity within the olfactory bulb and interacting intricately with higher-order brain regions. The role of adult neurogenesis in olfactory bulb functions remains a topic of debate. Nevertheless, the functionality of the olfactory bulb is intricately linked to the organization of granule cells around mitral and tufted cells. This organizational pattern significantly impacts output, network behavior, and synaptic plasticity, which are crucial for olfactory perception and memory. Additionally, this organization is further shaped by axon terminals originating from cortical and subcortical regions. Despite the crucial role of olfactory bulb in brain functions and behaviors related to olfaction, these complex and highly interconnected processes have not been comprehensively studied as a whole. Therefore, this manuscript aims to discuss our current understanding and explore how neural plasticity and olfactory neurogenesis contribute to enhancing the adaptability of the olfactory system. These mechanisms are thought to support olfactory learning and memory, potentially through increased

关键词： network adaptability neurogenesis neuronal communication olfactory bulb olfactory learning olfactory memory synaptic plasticity

metal-modulated epitaxy of mg-doped Al_(0.80)In_(0.20)N-based layer for application as the electron blocking layer in deep ultraviolet light-emitting diodes

在线全文

学校读者我要写书评

暂无评论

Journal of Semiconductors 2024年第5期45卷 80-89页

作者： Horacio Irán Solís-Cisneros Carlos Alberto Hernández-Gutiérrez Enrique Campos-González máximo López-López Optomechatronics Group Tecnológico Nacional de México Campus Tuxtla Gutiérrezcarretera Panamericana 1080C.P.29050Tuxtla GutiérrezChiapasMéxico Departamento de Física Instituto Nacional de Investigaciones NuclearesCarretera México-Toluca s/nC.P.52750La Marquesa OcoyoacacMéxico Departamento de Física Centro de Investigación y estudios Avanzados del Instituto Politécnico NacionalAv.Instituto Politécnico Nacional 2508San Pedro ZacatencoGustavo A.Madero07360 Ciudad de MéxicoCDMXMéxico

This work reports the growth and characterization of p-AlInN layers doped with mg by plasma-assisted molecular beam epitaxy(PAmBE).AlInN was grown with an Al molar fraction of 0.80 by metal-modulated epitaxy(mmE)with a thickness of 180 nm on Si(111)substrates using AlN as buffer *** substrate temperatures were used to enhance the incorporation of indium atoms into the alloy without clustering,as confirmed by X-ray diffraction(XRD).Cathodoluminescence measurements revealed ultraviolet(UV)range ***,Hall effect measurements indicated a maximum hole mobility of 146 cm^(2)/(V∙s),corresponding to a free hole concentration of 1.23×10^(19)cm^(−3).The samples were analyzed by X-ray photoelectron spectroscopy(XPS)estimating the alloy composition and extracting the Fermi level by valence band ***-doped AlInN layers were studied for use as the electron-blocking layer(EBL)in LED *** varied the Al composition in the EBL from 0.84 to 0.96 molar fraction to assess its theoretical effects on electroluminescence,carrier concentration,and electric field,using SILVACO *** results from this study highlight the importance and capability of producing high-quality mg-doped p-AlInN layers through *** simulations suggest that an Al content of 0.86 is optimal for achieving desired outcomes in electroluminescence,carrier concentration,and electric field.

关键词： metal-modulated epitaxy AlInN DUV-LED EBL simulation

A core-satellite self-assembled SERS aptasensor containing a“biological-silent region”Raman tag for the accurate and ultrasensitive detection of histamine

在线全文

学校读者我要写书评

暂无评论

Food Science and Human Wellness 2024年第2期13卷 1029-1039页

作者： Chen Chen Yingfang Zhang ximo Wang Xuguang Qiao Geoffrey I.N.Waterhouse Zhixiang Xu Key Laboratory of Food Processing Technology and Quality Control in Shandong Province College of Food Science and EngineeringShandong Agricultural UniversityTai’an 271018China School of Chemical Sciences The University of AucklandAuckland 1142New Zealand

Herein,a novel interference-free surface-enhanced Raman spectroscopy(SERS)strategy based on magnetic nanoparticles(mNPs)and aptamer-driven assemblies was proposed for the ultrasensitive detection of histamine.A core-satellite SERS aptasensor was constructed by combining aptamer-decorated Fe_(3)O_(4)@Au mNPs(as the recognize probe for histamine)and complementary DNA-modified silver nanoparticles carrying 4-mercaptobenzonitrile(4-mBN)(Ag@4-mBN@Ag-c-DNA)as the SERS signal probe for the indirect detection of *** an applied magnetic field in the absence of histamine,the assembly gave an intense Raman signal at“Raman biological-silent”region due to *** the presence of histamine,the Ag@4-mBN@Ag-c-DNA SERS-tag was released from the Fe_(3)O_(4)@Au mNPs,thus decreasing the SERS *** optimal conditions,an ultra-low limit of detection of 0.65×10^(-3)ng/mL and a linear range 10^(-2)-10^5 ng/mL on the SERS aptasensor were *** histamine content in four food samples were analyzed using the SERS aptasensor,with the results consistent with those determined by high performance liquid *** present work highlights the merits of indirect strategies for the ultrasensitive and highly selective SERS detection of small biological molecules in complex matrices.

关键词： Surface-enhanced Raman spectroscopy Raman biological-silent region Aptamer Histamine detection Universal SERS-tag

NiWO4 powders prepared via polymeric precursor method for application as ceramic luminescent pigments

在线全文

学校读者我要写书评

暂无评论

Journal of Advanced Ceramics 2020年第1期9卷 55-63页

作者： Naiara A.LImA Lorena D.S.ALENCAR máximo SIU-LI Carlos A.C.FEITOSA Alexandre mESQUITA Jean-Claude m’PEKO maria I.B.BERNARDI Instituto de Física de Sao Carlos Universidade de Sao Paulo13560-970 Sao CarlosSPBrazil Instituto Federal de mato Grosso do Sul IFMS79200-000 AquidauanaMSBrazil Departamento de Física Centro de Ciências Exatas e TecnologiaUniversidade Federal do MaranhaoUFMA65080-805Sao LuisMABrazil Instituto de Geociências e Ciências Exatas Departamento de FísicaUniversidade Estadual Paulista13506-900Rio ClaroSPBrazil

Ni WO4 was prepared using the polymeric precursor method and studied in terms of physical and chemical properties to verify its stability for industrial applications as *** characterization was accomplished using thermal analyses,X-ray diffraction(XRD),scanning electron microscopy(SEm),photoluminescence(PL)and UV–Vis spectroscopies,colorimetric coordinates,and Raman *** the temperature,successive exothermic reactions were observed and they are related with thermal decomposition of the organic *** stability was reached at^700℃.The material is verified to become completely free of second phase at^800℃.The end Ni WO4 powders showed an intense charge transfer(CT)-related tail centered in the ultraviolet region,resulting in a yellow *** addition,the powders exhibited broad excitation band and broad deep blue–green emission band,which were enhanced with increasing powders’crystallinity.

关键词： nickel tungstate yellow pigment colorimetric coordinate optical property structural characterization